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Resting state brain default network in patients with motor aphasia resulting from cerebral infarction

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Chinese Science Bulletin 2014年第31期59卷 4069-4076页

作者： Xin wang Meihao wang weizhuo wang Huiru Liu Jiejie Tao Chuang Yang Jiance Li Department of Radiology First Affiliated Hospital of Wenzhou Medical University Department of Radiology Nankai Hospital of Tianjin Department of Psychiatry First Affiliated Hospital of Wenzhou Medical University

To explore the brain default mode network(DMN)in patients with motor aphasia resulting from cerebral infarction,we used resting state functional magnetic resonance imaging(fMRI)to investigate the possible neural *** patients with motor aphasia resulting from cerebral infarction and ten matched controls were selected in this *** subjects were examined using resting state *** chose the posterior cingulate cortex as the region of interest and then used functional connectivity analysis to calculate the DMN functional connectivity and analyze differences in the functional connectivity between the two *** with normal controls,aphasia patient group showed a significantly decreased functional connectivity in bilateral medial frontal gyrus,superior frontal gyrus,middle frontal gyrus,middle temporal gyrus,precuneus and *** aphasia patient group showed increased functional connectivity mainly in bilateral medial frontal gyrus,middle frontal gyrus,inferior frontal gyrus,precentral gyrus,*** DMN in cerebral infarction motor aphasia patients showed significantly decreased functional connectivity in the resting *** DMN most likely plays an important role in motor aphasia resulting from cerebral ***,functional connectivity in the brain regions surrounding the left and right Broca’s areas was significantly enhanced due to compensatory *** may be helpful for the recovery of language function in cerebral infarction patients with motor aphasia.

关键词：运动性患者大脑状态静息网络功能磁共振成像显示功能

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Science China(Life Sciences) 2012年第12期55卷 1057-1063页

作者： LI ChunYan wang weizhuo GUO Xlong ZHANG Feng MA WeiJuan ZHANG YinGang LI YouFen BAI YiDong LAMMI Mikko J Faculty of Public Health Medical College of Xi'an Jiaotong University Key Laboratory of Environment and Gene Related Diseases of Min- istry of Education Key Laboratory of Trace elements and Endemic Diseases of Ministry of Health Xi'an 710061 China 1nstitute of Health Education of Xi'an Xi'an 710004 China Department of Orthopedics Surgery Second Hospital Xi'an Jiaotong University Xi'an 710004 China Department of Orthopedics Surgery First Hospital Xi'an Jiaotong University Xi'an 710061 China School of Life Science and Technology Xi'an Jiaotong University Xi'an 710049 China Department of Cellular and Structural Biology University of Texas Health Sciences Center at San Antonio San Antonio Texas 78229 USA Department of Anatomy Institute of Biomedicine University of Kuopio Kuopio F1N-70211 Finland

In this paper, we present the first evidence of differences in the mitochondria-related gene expression profiles of adult articular cartilage derived from patients with Kashin-Beck disease and normal controls. The expression of 705 mitochondria-related genes was analyzed by mitochondria-related gene expression analysis and ingenuity pathways analysis. Mitochondria-related gene expression analysis identified 9 up-regulated genes in Kashin-Beck disease based on their average expression ratio. Three canonical pathways involved in oxidative phosphorylation, apoptosis signaling and pyruvate metabolism were identified, which indicate the involvement of mitochondrial dysfunction in the pathogenesis of Kashin-Beck disease.

关键词： Kashin-Beck disease microarray mitochondrial dysfunction IPA analysis

Damage Identification of Wind Turbine Blades–A Brief Review

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Journal of Dynamics, Monitoring and Diagnostics 2023年第3期2卷 198-206页

作者： Amna Algolfat weizhuo wang Alhussein Albarbar Department of Engineering Manchester Metropolitan UniversityManchesterM15GDUK

The increasing size of these blades of wind turbines emphasizes the need for reliable monitoring and *** brief review explores the detection and analysis of damage in wind turbine *** study highlights various techniques,including acoustic emission analysis,strain signal monitoring,and vibration analysis,as effective approaches for damage *** analysis,in particular,shows promise for fault identification by analyzing changes in dynamic *** indices based on modal properties,such as natural frequencies,mode shapes,and curvature,are discussed.

关键词： damage modeling digital twin vibration-based indices wind turbine blade

Dynamic Response Analysis of A 5 MW NREL Wind Turbine Blade under Flap-Wise and Edge-Wise Vibrations

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Journal of Dynamics, Monitoring and Diagnostics 2022年第4期1卷 208-222页

作者： Amna Algolfat weizhuo wang Alhussein Albarbar Infrastructure and Industry Research Group Department of EngineeringManchester Metropolitan UniversityManchesterM15GDUK

A wind turbine is subjected to a regime of varying *** example,each rotor revolution causes a complete gravity stress reversal in the low-speed shaft,and there are varying stresses from the out-of-plane loading cycle due to fluctuating wind ***,wind turbine blade design is governed by fatigue rather than ultimate load *** studies have adopted many different beam theories,using different techniques and codes,to model the National Renewable Energy Laboratory(NREL)5MWoffshore wind turbine *** are differences,from study to study,in the free vibration results and the dynamic *** contribution of this study is to apply the code written by the authors to the different beam theories used with the aim of comparing the different beam theories presented in the literature and that developed by the *** paper reports the investigation of the effects of deformation parameters on the dynamic characteristics of the NREL 5 MW offshore wind turbine blades predicted by the different beam *** investigation of free vibrations is a fundamental step in the analysis of structural dynamics,and this study compares different computational structural methods and investigates their effect on the predicted dynamic *** modal characteristics of every model examined have been combined with strip theory to determine the dynamic response of the blade.

关键词： blade dynamic response edge-wise vibration free vibration analysis flap-wise vibration wind turbine vibration

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干眼动物模型与干眼药物研发

中华实验眼科杂志 2018年第12期36卷 956-961页

作者：王未琢(综述) 陈苗程凌云(审校) 温州医科大学眼科药物研究所 325027 美国加州大学圣地亚哥分校医学院 Shiley眼科研究所加利福尼亚92093

干眼是目前常见的慢性眼表疾病,主要表现为眼表的慢性炎症并严重威胁视力。尽管干眼发病普遍,但特效的治疗药物却很少。这与干眼的多样性和相应动物干眼模型的匮乏有关。在药物开发过程中,临床前期的动物模型是评估在研药物安全性和治... 详细信息

干眼是目前常见的慢性眼表疾病,主要表现为眼表的慢性炎症并严重威胁视力。尽管干眼发病普遍,但特效的治疗药物却很少。这与干眼的多样性和相应动物干眼模型的匮乏有关。在药物开发过程中,临床前期的动物模型是评估在研药物安全性和治疗效果的重要环节。目前干眼研究中常见的造模方法有手术摘除泪腺、全身或局部药物诱导、人为介导自身免疫反应及基因工程介导的干眼,本文就近年来用于药物研发的干眼动物模型及其特点进行综述,为开发新的治疗药物提供参考.

关键词：干眼动物模型药物筛选药物试验疗效评估

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端基对固态电解质离子传输和传热性能的影响

工程热物理学报 2024年第5期45卷 1464-1469页

作者：王家歧樊林浩李伟卓焦魁杜青天津大学内燃机燃烧学国家重点实验室天津300350

本文研究了不同端基聚合物下聚环氧乙烷(PEO)和双(三氟甲磺酰亚胺)锂盐(LiTFSI)固体聚合物电解质的离子扩散系数和热导率,并对其结构性质进行了分析,以研究离子输运和热传导机理。结果表明,以端甲氧基聚环氧乙烷为基体电解质具有较好的... 详细信息

本文研究了不同端基聚合物下聚环氧乙烷(PEO)和双(三氟甲磺酰亚胺)锂盐(LiTFSI)固体聚合物电解质的离子扩散系数和热导率,并对其结构性质进行了分析,以研究离子输运和热传导机理。结果表明,以端甲氧基聚环氧乙烷为基体电解质具有较好的离子传输性能,因为更多的自由锂离子能够传输。然而,其导热性质更差,因为声子谱转移到更高的频率,这表明高频声子散射的增强导致热导率降低。这些结论对PEO-LiTFSI电解质设计有着很好的指导意义。

关键词：固体聚合物电解质分子动力学离子传输热导率

纳洛酮与氨茶碱联合治疗小儿急性呼吸衰竭的临床疗效观察

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菏泽医学专科学校学报 2015年第4期27卷 26-27,82页

作者：王卫卓张婵菏泽医学专科学校山东菏泽274000

目的探讨纳洛酮与氨茶碱联合治疗急性呼吸衰竭的效果。方法急性呼吸衰竭患儿50例,随机分为两组,对照组患儿采取常规治疗,观察组患儿采取纳洛酮与氨茶碱联合治疗。结果治疗组有效率为92.0%,对照组有效率为80.0%,两组比较有显著性差异。... 详细信息

目的探讨纳洛酮与氨茶碱联合治疗急性呼吸衰竭的效果。方法急性呼吸衰竭患儿50例,随机分为两组,对照组患儿采取常规治疗,观察组患儿采取纳洛酮与氨茶碱联合治疗。结果治疗组有效率为92.0%,对照组有效率为80.0%,两组比较有显著性差异。结论采用纳洛酮与氨茶碱联合治疗小儿急性呼吸衰竭效果显著,值得推广。

关键词：小儿急性呼吸衰竭/治疗纳洛酮/治疗应用氨茶碱/治疗应用

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基于OneNET云平台的室内环境监测系统

科技资讯 2023年第11期21卷 18-21页

作者：薛鸿民王炜卓陕西学前师范学院信息工程学院陕西西安710100

随着物联网、区块链、大数据和人工智能的发展,环境监测行业迅猛发展,但目前很多环境基础设施依旧存在简陋、陈旧,且缺乏现代化的缺憾。为了更加高效、精准地获取当前室内环境的各类信息,实现环境信息精准监测,笔者设计了一种基于OneNE... 详细信息

随着物联网、区块链、大数据和人工智能的发展,环境监测行业迅猛发展,但目前很多环境基础设施依旧存在简陋、陈旧,且缺乏现代化的缺憾。为了更加高效、精准地获取当前室内环境的各类信息,实现环境信息精准监测,笔者设计了一种基于OneNET云平台的室内环境监测系统。该系统采用ZigBee开发板,以CC2530芯片作为数据处理的核心,实现数据的无线传输,并通过智能感知、存储以及计算与室内环境的多维度数据融合技术,实现了基于多源感知节点的室内环境智能监测与自动控制等功能。

关键词：物联网室内环境监测 OneNET云平台 ZigBee无线通信

基于ZigBee和云平台的智慧养殖环境监测系统设计

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现代信息科技 2022年第5期6卷 164-167,171页

作者：薛鸿民王炜卓陕西学前师范学院信息工程学院陕西西安710100

畜牧业是我国经济发展的基础产业,传统的养殖场主要采用人工养殖,实行粗放式管理,不仅浪费人力物力,也不能实时有效地监管养殖场环境。为此,设计出一种基于ZigBee和云平台的智慧养殖环境监测系统,借助ZigBee模块采集养殖环境中的各项信... 详细信息

畜牧业是我国经济发展的基础产业,传统的养殖场主要采用人工养殖,实行粗放式管理,不仅浪费人力物力,也不能实时有效地监管养殖场环境。为此,设计出一种基于ZigBee和云平台的智慧养殖环境监测系统,借助ZigBee模块采集养殖环境中的各项信息,并通过Wi-Fi模块发送至OneNET云平台,实现对数据的实时监测与管理。测试结果表明,该系统扩展性强,节点数目易于改变,具有很强的实用价值。

关键词：物联网智慧养殖 ZigBee OneNET云平台