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Timing of antiviral therapy in patients with hepatitis B virus related hepatocellular carcinoma undergoing hepatectomy

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World Journal of Clinical Oncology 2024年第9期15卷 1251-1255页

作者： Dong-ling wan Li-Qi Sun Department of Gastroenterology Changhai HospitalNaval Medical UniversityShanghai 200433China Department of Gastroenterology 72th Group Army HospitalHuzhou 313000Zhejiang ProvinceChina

Globally,hepatocellular carcinoma(HCC)is among the most prevalent and deadly *** B virus(HBV)infection is an important etiology and disease progression factor for *** is a widely accepted curative treatment for HCC,but the long-term survival rate is still unsatisfactory due to the high recurrence rate after *** or postoperative antiviral therapy plays an important role in improving the prognosis for HBV-related HCC patients who underwent ***,many patients miss out on the chance to receive long-term preoperative antiviral medication because their HBV and HCC infections are discovered concurrently,necessitating the start of remedial antiviral therapy in the perioperative ***,it is of great value to know when antiviral therapy is more appropriate and whether perioperative rescue antiviral therapy can achieve the effect of preoperative long-term antiviral therapy.

关键词： Hepatocellular carcinoma Hepatitis B virus Hepatectomy Antiviral therapy Hepatitis B virus-DNA Hepatitis B virus-DNA

High-resolution ARPES endstation for in situ electronic structure investigations at SSRF

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Nuclear Science and Techniques 2021年第3期32卷 94-106页

作者： Yi-Chen Yang Zheng-Tai Liu Ji-Shan Liu Zhong-Hao Liu wan-ling Liu Xiang-Le Lu Hong-Ping Mei Ang Li Mao Ye Shan Qiao Da-Wei Shen State Key Laboratory of Functional Materials for Informatics Shanghai Institute of Microsystem and Information TechnologyChinese Academy of SciencesShanghai 200050China University of Chinese Academy of Sciences Beijing 100049China

Angle-resolved photoemission spectroscopy(ARPES)is one of the most powerful experimental techniques in condensed matter *** ARPES,which uses photons with high flux and continuously tunable energy,has become particularly ***,an excellent synchrotron ARPES system must have features such as a small beam spot,super-high energy resolution,and a user-friendly operation interface.A synchrotron beamline and an endstation(BL03 U)were designed and constructed at the Shanghai Synchrotron Radiation *** beam spot size at the sample position is 7.5(V)μm×67(H)μm,and the fundamental photon range is 7-165 eV;the ARPES system enables photoemission with an energy resolution of 2.67 meV at21.2 *** addition,the ARPES system of this endstation is equipped with a six-axis cryogenic sample manipulator(the lowest temperature is 7 K)and is integrated with an oxide molecular beam epitaxy system and a scanning tunneling microscope,which can provide an advanced platform for in situ characterization of the fine electronic structure of condensed matter.

关键词： Synchrotron ARPES In situ VUV laser Quantum materials

Surfactant-Enhanced Phytoremediation of Soils Contaminated with Hydrophobic Organic Contaminants:Potential and Assessment

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Pedosphere 2007年第4期17卷 409-418页

作者： GAO Yan-Zheng ling wan-Ting ZHU Li-Zhong ZHAO Bao-Wei ZHENG Qing-Song College of Resource and Environmental Sciences Nanjing Agricultural University Nanjing 210095 College of Environmental and Resource Sciences Zhejiang University Hangzhou 310028 （China） School of Environmental and Municipal Engineering Lanzhou Jiaotong University Lanzhou 730070 （China）

Phytoremediation is becoming a cost-effective technology for the in-situ clean up of sites polluted with hydrophobic organic contaminants （HOCs）. The major factors limiting phytoremediation are the mass transfer, rate of plant uptake, and microbial biodegradation of HOCs. This article discusses the potential of surfactants to enhance desorption, plant uptake, and biodegradation of HOCs in the contaminated sites. Positive effects of surfactants on phytoremediation have been recently observed in greenhouse studies. The presence of some nonionic surfactants including polyoxyethylene sorbltan monooleate （Tween 80） and polyoxyethylene（23）dodecanol （Brij35） at relatively low concentrations resulted in significant positive effects on phytoremediation for pyrene-contaminated soil. However, the anionic surfactant （sodium dodecyl sulfate, SDS） and the cationic surfactant （cetyltrimethylammonium bromide, CTMAB） were not useful because of their phytotoxicity or low efficiency for surfactant-enhanced phytoremediation （SEPR）. The mechanisms of SEPR for HOC-contaminated sites were evaluated by considering experimental observations. In view of concerns about the cost effectiveness and toxicity of surfactants to plants, more research is needed to enhance the use of SEPR technology.

关键词： hydrophobic organic contaminant remediation SEPR soil surfaztant

Suppression mechanisms on proliferation of glioma U251 cells by FePt nanoparticles through intracellular oxidative stress

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Rare Metals 2022年第4期41卷 1202-1209页

作者： Yao-Min Li Li-Hui Meng Yan-Ru Hu Tian-Tian Zhang Zheng-Nan Su Zhi-Yuan Ouyang Wen-Chao Li Jiang-ling wan Qing-Zhi Wu State Key Laboratory of Advanced Technology for Materials Synthesis and Processing and Biomedical Materials and Engineering CentreWuhan University of TechnologyWuhan 430070China National Engineering Research Centre for Nanomedicine College of Life Science and TechnologyHuazhong University of Science and TechnologyWuhan 430074China

FePt nanoparticles(NPs)have attracted a great deal of attention in biomedical applications due to their excellent superparamagnetic property and anticancer activity,which display promising potential as the MRI/CT contrast imag-ing agent for cancer detection and *** this study,the suppression mechanism induced by FePt NPs on U251 cells is *** U251 cells are co-cultured with FePt NPs at different concentrations,and the intra-cellular oxidative stress was studied by detecting the activities of various redox enzymes and expression of several apoptosis-related *** cell viability assay shows that the highest suppression on the proliferation of glioma U251 cells is 10.5%±5.6%after treatment with 5μg·ml^(-1)FePt NPs for 24 *** this case,the LDH release remarkably *** cytometry and fluorescence assay show that FePt NPs promote the apoptosis and G0/G1 phase arrest of U251 cells.

关键词： nanoparticles U251 stress

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电子文档长期存取的跨媒体开放文件格式

中国图书馆学报 2007年第3期33卷 60-63页

作者：宛玲河北大学管理学院

PDF/A和ODF是采用与平台和设备无关的开放文件格式标准,有利于低成本高质量进行电子文档的长期存取。作为新出台的国际标准,它们在电子文档长期存取方面具有重要作用,可以实现异构系统的互操作,降低维护长期存取活动的成本,消除对特定... 详细信息

PDF/A和ODF是采用与平台和设备无关的开放文件格式标准,有利于低成本高质量进行电子文档的长期存取。作为新出台的国际标准,它们在电子文档长期存取方面具有重要作用,可以实现异构系统的互操作,降低维护长期存取活动的成本,消除对特定软件厂商的过度依赖并促进办公软件的发展,在后续的发展上具有很好的透明性和可靠性。但二者在应用中仍然存在较大的差异,开放性也有一定的局限。参考文献12。

关键词： PD//A ODF 文件格式国际标准电子文档文档存取

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数字资源长期存取权益管理技术策略

情报理论与实践 2006年第1期29卷 57-59页

作者：宛玲河北大学管理学院河北071002

数字资源长期存取权益管理技术策略主要包括存储管理、访问控制管理、使用控制管理、信息交互管理和付费管理等。本文从权益角度,对这些策略进行了分析。

关键词：信息资源信息存取/数字权益管理

Effects of Recombinant Human Growth Hormone on Corneal Healing, Epithelial Nerve Regeneration and Tear Inflammatory Factors in Rabbits

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Chinese Journal of Biomedical Engineering(English Edition) 2023年第2期32卷 55-64页

作者： CHEN wan-ling ZHANG Cheng-yuan LIU Hai-hua Longyan First Affiliated Hospital of Fujian Medical University Fujian Longyan 364400China

Objective:The goal of this study is to investigate the effects of recombinant human growth hormone(rh GH)on corneal healing,epithelial nerve regeneration and tear inflammatory factor levels in ***:After corneal epithelial injury models were established,fifty adult clean New Zealand white rabbits were randomly divided into two groups,normal saline was administered to the control group,while recombinant human growth hormone was administered to the observation *** healing rate of corneal epithelial injury,the regeneration ability of corneal epithelial nerve and the level of inflammatory factors in tears were observed and compared between the two groups of rabbits before and 24,48,72 and 96 h after ***:There were significant differences in corneal epithelial healing rate,time and interaction between the two groups(Pling rate of corneal epithelium at 24,48,72,and 96 h compared to the control group(Pling and at 24,72 and 96 h after modeling(P>0.05),whereas the experimental group exhibited a higher central corneal sensitivity compared to the control group at 48 h after modeling(Pling(Pling(P<0.05),and the level of TNF-αin the experimental group was significantly lower than that of the control group

关键词： recombinant human growth hormone rabbits corneal epithelial injury epithelial nerve regeneration inflammatory factors

Multiorgan dysfunction syndrome due to high-dose cantharidin poisoning:A case report

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World Journal of Clinical Cases 2024年第12期12卷 2074-2078页

作者： wan-ling Xu Wen-Jing Tang Wei-Ying Yang Li-Chao Sun Ze-Qun Zhang Wei Li Xiu-Xian Zang Department of Emergency Medicine First Hospital of Jilin UniversityChangchun 130021Jilin ProvinceChina Department of Chinese Traditional Medicine First Hospital of Jilin UniversityChangchun 130021Jilin ProvinceChina

BACKGROUND This report delves into the diagnostic and therapeutic journey undertaken by a patient with high-dose cantharidin poisoning and multiorgan dysfunction syndrome(MODS).Particular emphasis is placed on the comprehensive elucidation of the clinical manifestations of high-dose cantharidin poisoning,the intricate path to diagnosis,and the exploration of potential underlying *** SUMMARY A patient taking 10 g of cantharidin powder orally subsequently developed *** patient was treated with supportive care,fluid hydration and antibiotics,and hemoperfusion and hemofiltration therapy for 24 h and successfully recovered 8 d after hospital *** poisoning can cause lifethreatening MODS and is rare *** case underscores the challenge in diagnosis and highlights the need for early clinical differentiation to facilitate accurate assessment and prompt *** This article has reported and analyzed the clinical data,diagnosis,treatment,and prognosis of a case of high-dose cantharidin poisoning resulting in MODS and reviewed the relevant literature to improve the clinical understanding of this rare condition.

关键词： Cantharidin Poisoning Multiorgan dysfunction syndrome Clinical treatment and management Case report

One-stage revision arthroplasty in a patient with ochronotic arthropathy accompanied by joint infection:A case report

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World Journal of Clinical Cases 2022年第25期10卷 9036-9043页

作者： Xiao-Chao wang Xiao-Min Zhang wan-ling Cai Zhen Li Chao Ma Yi-Hai Liu Qi-Lian He Tian-Sheng Yan Xue-Wei Cao The Second Clinical Medical College Guangzhou University of Chinese MedicineGuangzhou 510000Guangdong ProvinceChina Department of Orthopaedics Xi’an International Medical Center HospitalXi’an 710100Shaanxi ProvinceChina Department of Surgery Baoji Hospital of Traditional Chinese MedicineBaoji 721000Shaanxi ProvinceChina Department of Orthopaedic Surgery Guangdong Provincial Hospital of Traditional Chinese MedicineGuangzhou 510120Guangdong ProvinceChina

BACKGROUND Ochronotic arthropathy(OcA)is a rare disease,which is caused by the accumulation of homogentisic acid in the *** with OcA have obvious joint pain and the disease progresses rapidly,eventually resulting in *** is an efficacious treatment in patients with ***,when OcA patients have joint infection,is joint replacement an option?In the present report,we performed total knee arthroplasty in a patient with OcA and knee infection under the guidance of one-stage revision *** SUMMARY A 64-year-old male was referred to our hospital due to severe left knee pain with limited mobility for 2 *** physical examination,the patient was found to have dark brown pigmentation of the sclera and *** test results showed elevations in C-reactive protein level(65.79 mg/L)and erythrocyte sedimentation rate(90.00 mm/h).The patient underwent debridement of the left knee joint,during which the cartilage surface of the knee joint was found to be black-brown in *** culture of synovial fluid revealed Achromobacter *** then carried out arthroplasty under the guidance of the theory of one-stage *** surgery,the patient’s left knee joint pain disappeared and function recovered without joint *** OcA accompanied by joint infection is ***-stage revision arthroplasty may be a treatment option for this disease.

关键词： Ochronotic arthropathy Arthroplasty One-stage revision Alkaptonuria Homogentisic acid Case report