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molecular and Serological Epidemiology of Foot-and-mouth Disease Virus in North Region of Cameroon

Advances in microbiology 2022年第10期12卷 579-595页

作者： Simon Jumbo Dickmu Julius Awah-Ndukum Niba Tatanja Aziwo Silas Lendzele Sevidzem mohamed moctar mouliom mouiche Carla Bravo de Rueda Labib Bakkali Kassimi Abel wade Rebecca Garabed Abdul-Dahiru El-Yuguda Luis Rodriguez Saka Saheed Baba Laboratoire National Vétérinaire LANAVET Garoua Cameroon Department of Animal Production Technology College of Technology The University of Bamenda Bamenda Cameroon Institute of Research in Tropical Ecology (IRET) Libreville Gabon Ecole des Sciences et de médecine Vétérinaire Université de Ngaoundéré Ngaoundere Cameroon Foreign Animal Disease Research Unit United States Department of Agriculture Agricultural Research Service Plum Island Animal Disease Centre Greenport USA Agence Nationale de Sécurité Sanitaire de l’Alimentation de l’Environnement et du Travail Pierre et Marie Curie Maisons-Alfort France Department of Veterinary Preventive medicine The Ohio State University Columbus USA Department of Veterinary microbiology and Parasitology Faculty of Veterinary Medicine University of Maiduguri Maiduguri Nigeria

The serological prevalence of foot and mouth disease virus (FmDV) among the cattle population in the North region of Cameroon was determined using ELISA (Enzyme Linked Immunosorbent Assays) serological tests for structural as well as non-structural proteins. In these cattle, FmDV RNA was identified, amplified, sequenced and the sequences were used to construct a phylogenetic tree. A sedentary cattle population randomly selected from six veterinary centres in the North region was sampled twice, six months apart. High prevalence of FmDV antibody was recorded in the first (402/466 (85.84%)) and second (358/411 (86.90%)) sampling periods. There was no significant difference (P > 0.05) in prevalence of FmDV antibody between the two sampling periods. Goudali and Peulh breeds of cattle and animals of three to five years old were the most infected with FmDV and mostly in the months of may and August. A seroprevalence of 100% (n = 14) of FmDV against serotypes A and O was observed in sera from convalescent animals in the study area. FmDV antigen detection ELISA showed a prevalence of 18/37 (48.65%) for serotypes SAT1 (8.1%), SAT2 (35.1%), A (10.8%) and O (2.7%) among the clinically infected animals. There was no significant difference (P > 0.05) in prevalence of FmDV RNA between the sampling periods. A prevalence of FmDV RNA (17.5% (n = 120) and 16.7% (n = 240)) was observed among the sedentary animals that were sampled four to five months apart. FmDV RNA prevalence of 28/37 (75.6%) among clinically infected animals was also observed, thus confirming all the 12 outbreaks investigated. Sequence analysis of VP1 coding gene of the SAT2 serotype showed that it was homologous to the Libyan isolates (that caused epidemics in northern Africa in 2012) and also clustered with the serotypes isolated from both Nigeria and Sudan in 2007.

关键词： Foot-and-mouth Disease Seroprevalence Non-Structural Protein Structural Protein ELISA Sedentary Cattle North Cameroon

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Effects of Inspiratory muscle Training on Heart Rate Variability in Children with Cystic Fibrosis:A Pilot Study

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Journal of Science in Sport and Exercise 2021年第1期3卷 66-74页

作者： J.L.mcCreery K.A.mackintosh m.A.mcNarry School of Sport and Exercise Science Swansea UniversityWalesUK

Purpose Cystic Fibrosis(CF)is a multisystem disease associated with symptoms such as dyspnoea,tachycardia and tachyp-nea that may be related to changes in autonomic function and sensitive to improvement following inspiratory muscle training(ImT).The aim of the present study was to investigate the effect of ImT on heart rate variability(HRV)and respiratory function in *** Five CF and five matched controls(40%boys)performed a 4-weeks ImT programme,involving 30 breaths,twice a *** 1-2 of training were set at 40%of a participant's maximal strength index(***),with week's 3-4 set at 50%.Participants wore an ActiHeart for three consecutive days at baseline and post-intervention and indices of HRV were *** measures of lung function were obtained along with health-related quality of life(HRQoL)using the CF-specific questionnaire(CFQ-R).Results ImT elicited clinically meaningful increases in respiratory muscle strength and respiratory symptom domain scores,but no improvements in respiratory volume,irrespective of ***,no significant improvements were found in HRQoL despite 62.5%of the population increased their HRQoL ***-intervention,CF participants showed a clinically meaningful decrease in the very low frequency(VLF)*** These results may indicate clinically meaningful changes in HRV and inspiratory muscle strength following a 4-week ImT intervention,although a more powerful study is required to draw further ***,the trends for improved HRQoL support the need for such studies to ascertain the potential therapeutic role of ImT in those with CF.

关键词： Cardiac function Paediatrics Chronic disease Quality of life Respiratory muscle training

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An acute naproxen dose does not affect core temperature or Interleukin-6 during cycling in a hot environment

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Sports medicine and Health Science 2021年第4期3卷 243-251页

作者： Dawn m.Emerson Stephen CL.Chen Toni m.Torres-mcGehee Craig E.Pfeifer Charles C.Emerson J.mark Davis Department of Physical Therapy Rehabilitation Scienceand Athletic TrainingSchool of Health ProfessionsUniversity of Kansas Medical Center3901 Rainbow BlvdMS 2002Kansas CityKansas66160USA. Division of Exercise and Sport Science Bob Jones University1700 Wade Hampton BlvdGreenvilleSouth Carolina29614USA. Department of Exercise Science Arnold School of Public HealthUniversity of South Carolina921 Assembly StreetColumbiaSC29208USA Applied Sport and Exercise Sciences The ParkUniversity of GloucestershireCheltenham GL502RHUnited Kingdom. Department of Athletics 5100 Rockhill Rd SRC 201University of Missouri-Kansas CityKansas CityMissouri64110USA.

Non-steroidal anti-inflammatory drugs’anti-pyretic and anti-inflammatory effects has led some individuals to theorize these medications may blunt core body temperature(Tc)increases during *** utilized a double-blind,randomized,and counterbalanced cross-over design to examine the effects of a 24-h naproxen dose(3–220 mg naproxen pills)and placebo(0 mg naproxen)on Tc and plasma interleukin-6(IL-6)concentrations during cycling in a hot or ambient ***(n=11;6 male,5 female;age=27.8±6.5 years,weight=79.1±17.9 kg,height=177±9.5 cm)completed 4 conditions:1)placebo and ambient(Control);2)placebo and heat(Heat);3)naproxen and ambient(Npx);and 4)naproxen and heat(NpxHeat).Dependent measures were taken before,during,and immediately after 90 min of cycling and then 3 h after ***,Tc significantly increased pre-(37.1±0.4℃)to post-cycling(38.2±0.3℃,F_(1.7,67.3)=150.5,pmaximum Tc were not significantly different between ***-6 increased pre-(0.54±0.06 pg/ml)to post-exercise(2.46±0.28 pg/ml,pmained significantly higher than pre-at 3 h post-(1.17±0.14 pg/ml,95%CI=-1.01 to-0.23,p=0.001).No significant IL-6 differences occurred between conditions.A 24-h,over-the-counter naproxen dose did not significantly affect Tc or IL-6 among males and females cycling in hot or ambient environments.

关键词： Cytokine Exertional heat illness NSAIDs Thermoregulation Exercise

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英国气候变化风险评估

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水利水电快报 2012年第1期33卷 53-61页

作者： D.m.拉姆斯博滕 S.D.韦德 I.H.汤恩德左志安山松英国华灵富水力研究有限公司

英国政府目前正在着手对因气候变化造成的风险进行全面评估,并将制订适应气候变化的计划,以便为应对气候变化提供明确的指导,提高各行业适应气候变化的能力。以水的供需平衡为例,简要阐述了风险评估的过程与结果。结果表明,未来需水量... 详细信息

英国政府目前正在着手对因气候变化造成的风险进行全面评估,并将制订适应气候变化的计划,以便为应对气候变化提供明确的指导,提高各行业适应气候变化的能力。以水的供需平衡为例,简要阐述了风险评估的过程与结果。结果表明,未来需水量会随温度的上升而增加。因此,有必要采取节约用水和提高用水效率等措施。

关键词：气候变化变化风险风险评价英国

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Cell:研究揭示SIRT3在调节线粒体健康中的关键作用

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现代生物医学进展 2017年第6期17卷 I0004-I0004页

作者： Wen Yang Koji Nagasawa Christian münch Yingjie Xu Kyle Satterstrom Seungmin Jeong Sebastian D. Hayes mark P. Jedrychowski F. Sejal Vyas Elma Zaganjor Virginia Guarani Alison E. Ringel Steven P. Gygi J. wade Harper marcia C. Haigis Vascular Biology Program Boston Children’s Hospital Harvard Medical School Boston MA 02115 USA

就蛋白而言，去乙酰化酶（sirtuin）是令人喜欢的，而且因它们与衰老和年龄相关疾病相关联而受到人们的广泛关注。作为去乙酰化酶的来源，线粒体，也因在健康和疾病中的作用而闻名于世。来自美国哈佛医学院的marcia Haigis和她的团队从... 详细信息

就蛋白而言，去乙酰化酶（sirtuin）是令人喜欢的，而且因它们与衰老和年龄相关疾病相关联而受到人们的广泛关注。作为去乙酰化酶的来源，线粒体，也因在健康和疾病中的作用而闻名于世。来自美国哈佛医学院的marcia Haigis和她的团队从事基础研究。提出了一个较为深刻的问题：在细胞中。哪些蛋白与去乙酰化酶进行交谈？

关键词：线粒体 Cell 健康去乙酰化酶相关疾病基础研究医学院蛋白

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The effect of breaking sitting time with physical activity breaks on cognitive performance in young people with cerebral palsy:an exposure response cross-over feasibility design

Translational Exercise Biomedicine

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Translational Exercise Biomedicine 2024年第1期1卷 32-42页

作者： Shelly Coe Jo Cossington Johnny Collett Andy meaney Foteini mavrommati Yujun Ng Hooshang Izadi Will wade Dominika m.Pindus Oliver Bushnell Luke Whaymand Tim Theologis Emily Swift Ece Akgul Sam Allen Helen Dawes Centre for movement Occupational and Rehabilitation Sciences Department of Sport Health Sciences and Social WorkOxford Brookes UniversityOxfordUKOX30BP Oxford Brookes Centre for Nutrition and Health Department of Sport Health Sciences and Social WorkOxford Institute for Applied Health ResearchOxford Brookes UniversityOxfordUKOX30BP medical School University of ExeterExeterUK Specialised Translational Research Oxford Neuromuscular Group:STRONG Department of PaediatricsUniversity of OxfordJohn Radcliffe HospitalOxfordUK Cardiovascular medicine University of OxfordJohn Radcliffe HospitalOxfordUK Ace Centre Hollinwood Business CentreOldhamUK University of Illinois at Urbana-Champaign Department of Kinesiology and Community HealthUrbanaILUSA Beckman Institute for Advanced Science and Technology University of Illinois at Urbana-ChampaignUrbanaILUSA Neuroscience Program University of Illinois at Urbana-ChampaignUrbanaILUSA Nuffield Department of Orthopaedics Rheumatology and Musculoskeletal SciencesUniversity of OxfordBotnar Research CentreOxfordUK School of Clinical medicine Centre for Healthy Brain Ageing(CHeBA)Discipline of Psychiatry and Mental HealthUniversity of New South WalesSydneyAustralia NIHR Exeter BRC University of Exeter Medical SchoolDepartment of Public Health and Sports SciencesFaculty of Health and Life SciencesMedical School BuildingCollege of Medicine and HealthSt Lukes CampusExeterUK Nuffield Department of Clinical Neurosciences University of OxfordOxfordUK

Objectives To assess the feasibility of methods and estimate the potential effect of interrupting sedentary behaviour,with intermittent or continuous physical activity breaks,on cognitive performance in young people with Cerebral *** A randomised three-arm exposure response cross-over design with process *** were recruited throughout the Thames Valley,UK between 01/11/2018 to 31/03/*** three 2 h activity exposure visits included:(i)sitting only(controls),(ii)sitting plus 20 min of moderate-to-vigorous activity burst,or(iii)4×5 min of moderate-to-vigorous activity bursts,during a 2.5 h sedentary *** of feasibility were *** performance outcomes(using the Eriksen Flanker task and Forward and Backward Digit Span)were delivered before and after the 2 h testing *** 36 participants were randomised(age 13.2±2.7,Gross-motor Functional Classification System 1–3).Study retention was 83%across all three interventions and overall missing data for measures was 4%.A small intervention effect was found in reaction time in the 4×5 min physical activity exposure session compared to the sedentary control condition(0.42;95%CI 0.40 to 0.79).There were two research-related minor adverse effects,an allergic reaction to the FreeStyle Libre and feeling faint and vomiting after consumption of glucose *** events were resolved and participants continued with the *** The study design and intervention implementing short bursts of physical activity was feasible and indicated a potential effect on reaction time as a measure of cognitive performance in young people with cerebral palsy.

关键词： cerebral palsy physical activity cognitive performance child adolescent

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南方幼松的生物量计算

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国外林业 1980年第2期 11-13页

作者： m.Boyd Edwards W.Henry meNab 顾燕珠

对于营林工作者来讲,能够测定地上生物量不仅有助于估计幼松林分的生长量,还可以计算出由野火造成的损失量(wade和Ward 1975)。此外,如果所培育的树木是用来生产能量的,那么所有树木都将成为采

关键词：生物量疏伐树种现存量间伐回归法方程方程式计算公式幼树湿地松短叶松林分

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