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Recursive filtering of multi-rate cyber-physical systems with unknown inputs under adaptive event-triggered mechanisms

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Frontiers of Information Technology & Electronic Engineering 2024年第2期25卷 250-259页

作者： Ying SUN miaomiao FU Jingyang mao Guoliang wEI Business School University of Shanghai for Science and TechnologyShanghai200093China Shanghai Caoyang Vocational School Shanghai200333China School of Electrical and Electronic Engineering Shanghai Institute of TechnologyShanghai201418China School of Intelligent Emergency management University of Shanghai for Science and TechnologyShanghai200093China

Cyber-physical systems(CPSs)take on the characteristics of both multiple rates of information collection and processing and the dependency on information *** purpose of this paper is to develop a joint recursive filtering scheme that estimates both unknown inputs and system states for multi-rate CPSs with unknown *** cyberspace,the information transmission between the local joint filter and the sensors is governed by an adaptive event-triggered ***,the desired parameters of joint filters are determined by a set of algebraic matrix equations in a recursive way,and a sufficient condition verifying the boundedness of filtering error covariance is found by resorting to some algebraic operation.A state fusion estimation scheme that uses local state estimation is proposed based on the covariance intersection(CI)based fusion ***,an illustrative example demonstrates the effectiveness of the proposed adaptive event-triggered recursive filtering algorithm.

关键词： Cyber-physical systems multi-rate Joint recursive filtering Adaptive event-triggered mechanisms Unknown inputs

Transcriptomic and machine learning analyses identify hub genes of metabolism and host immune response that are associated with the progression of breast capsular contracture

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Genes & Diseases 2024年第3期11卷 427-437页

作者： Yukun mao Xueying Hou Su Fu Jie Luan Breast Plastic and Reconstructive Surgery Center Plastic Surgery HospitalChinese Academy of Medical SciencesPeking Union Medical CollegeBeijing 100144China

Capsular contracture is a prevalent and severe complication that affects the post-operative outcomes of patients who receive silicone breast *** present,prosthesis replacement is the major treatment for capsular contracture after both breast augmentation procedures and breast reconstruction following breast cancer ***,the mecha-nism(s)underlying breast capsular contracture remains *** study aimed to identify the biological features of breast capsular contracture and reveal the potential underlying mechanism using RNA *** tissues from 12 female patients(15 breast capsules)were divided into low capsular contracture(LCC)and high capsular contracture(HCC)groups based on the Baker ***,41 lipid metabolism-related genes were identified through enrichment analysis,and three of these genes were identified as candidate genes by SVm-RFE and LASSO *** then compared the proportions of the 22 types of im-mune cells between the LCC and HCC groups using a CIBERSORT analysis and explored the Cor-relation between the candidate hub features and immune ***,PRKAR2B was positively correlated with the differentially clustered immune cells,which were m1 macro-phages and follicular helper T cells(area under the ROC=0.786).In addition,the expression of PRKAR2B at the mRNA or protein level was lower in the HCC group than in the LCC *** molecular mechanisms were identified based on the expression levels in the high and low PRKAR2B *** findings indicate that PRKAR2B is a novel diagnostic biomarker for breast capsular contracture and might also influence the grade and progression of capsularcontracture.

关键词： Biomarker Breastcapsular contracture Immune infiltration machinelearning algorithms PRKAR2B

Comparative transcriptome analysis between rhesus macaques(macaca mulatta) and crab-eating macaques(m. fascicularis)

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Zoological Research 2024年第2期45卷 299-310页

作者： Yu-Xiang mao Yamei Li Zikun Yang Ning Xu Shilong Zhang Xuankai wang Xiangyu Yang Qiang Sun Yafei mao Institute of Neuroscience State Key Laboratory of NeuroscienceCenter for Excellence in Brain Science&Intelligence TechnologyChinese Academy of SciencesShanghai 200031China Shanghai Center for Brain Science and Brain-Inspired Intelligence Technology Shanghai 201210China University of Chinese Academy of Sciences Beijing 100049China Key Laboratory of Genetic Evolution&Animal models Chinese Academy of SciencesKunmingYunnan 650201China Bio-X Institutes Key Laboratory for the Genetics of Developmental and Neuropsychiatric DisordersMinistry of EducationShanghai Jiao Tong UniversityShanghai 200030China Zhiyuan College Shanghai Jiao Tong UniversityShanghai 200240China Center for Genomic Research International Institutes of MedicineFourth Affiliated HospitalZhejiang UniversityYiwuZhejiang 322000China

Understanding gene expression variations between species is pivotal for deciphering the evolutionary diversity in phenotypes. Rhesus macaques(macaca mulatta, mmU)and crab-eating macaques(m. fascicularis, mFA) serve as crucial nonhuman primate biomedical models with different phenotypes. To date, however, large-scale comparative transcriptome research between these two species has not yet been fully explored. Here, we conducted systematic comparisons utilizing newly sequenced RNA-seq data from84 samples(41 mFA samples and 43 mmU samples)encompassing 14 common tissues. Our findings revealed a small fraction of genes(3.7%) with differential expression between the two species, as well as 36.5% of genes with tissue-specific expression in both macaques. Comparison of gene expression between macaques and humans indicated that 22.6% of orthologous genes displayed differential expression in at least two tissues. moreover,19.41% of genes that overlapped with macaque-specific structural variants showed differential expression between humans and macaques. Of these, the FAm220A gene exhibited elevated expression in humans compared to macaques due to lineage-specific duplication. In summary,this study presents a large-scale transcriptomic comparison between mmU and mFA and between macaques and humans. The discovery of gene expression variations not only enhances the biomedical utility of macaque models but also contributes to the wider field of primate genomics.

关键词： Crab-eating macaques Rhesus macaques Comparative transcriptomics Biomedical models Nonhuman primates RNA-seq Duplicated genes

A multi-Token Sector Antenna Neighbor Discovery Protocol for Directional Ad Hoc Networks

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China Communications 2024年第7期21卷 149-168页

作者： Zhang Hang Li Bo Yan Zhongjiang Yang mao Li Xinru School of Electronics and Information Northwestern Polytechnical UniversityXi’an 710072China The 54th Research Institute of CETC Shijiazhuang 050081China

In this paper,we propose a multi-token Sector Antenna Neighbor Discovery(m-SAND)protocol to enhance the efficiency of neighbor discovery in asynchronous directional ad hoc *** central concept of our work involves maintaining multiple tokens across the *** prevent mutual interference among multi-token holders,we introduce the time and space non-interference ***,we propose a master-slave strategy between *** the master token holder(mTH)performs the neighbor discovery,it decides which 1-hop neighbor is the next mTH and which 2-hop neighbors can be the new slave token holders(STHs).Using this approach,the mTH and multiple STHs can simultaneously discover their neighbors without causing interference with each *** on this foundation,we provide a comprehensive procedure for the m-SAND *** also conduct theoretical analyses on the maximum number of STHs and the lower bound of multi-token generation ***,simulation results demonstrate the time efficiency of the m-SAND *** compared to the QSAND protocol,which uses only one token,the total neighbor discovery time is reduced by 28% when 6beams and 112 nodes are employed.

关键词： multi-token neighbor discovery SAND protocol sector antenna ad hoc network

Inclusions modification by rare earth in steel and the resulting properties: A review

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Journal of Rare Earths 2024年第3期42卷 431-445,I0001页

作者： Xiaoqiang wang Zhiwei wu Bing Li wenxiong Chen Jun Zhang Jian mao College of materials Science and Engineering Sichuan UniversityChengdu610065China Chengdu Advanced metal materials Industry Technology Research Institute Co. Ltd.Chengdu610303China State Key Laboratory of metal material for marine Equipment and Application Anshan114009China

Rare earth(RE) elements are excellent modifiers for non-metallic inclusions that inevitably appear in steel and affect steel properties. This paper reviews the research status of inclusions modification by RE elements and the changes it cause on steel properties. First, the inclusion changes caused by RE modification are described. Generally, after adding pure RE, the main evolution of inclusions occurs as m →m + RE-Al-O → RE-Al-O + RE_(2)O_(2)S → RE_(2)O_(2)S + RE—S/RE_(2)O_(2)S + RE-O with an increase in the RE content(m represents the inclusions before RE addition). The type of final inclusion obtained after RE modification is related to the relative contents of S and O in the steel. moreover, fine, regular, and uniformly distributed inclusions can be obtained with appropriate RE addition. However, the effectiveness of inclusions modification by adding both RE and non-RE elements is closely related to the order of their addition. Second, the applications and advantages of thermodynamic calculations in the study of RE-modified inclusions are introduced. Third, the changes in the corrosion resistance, impact properties,and other properties of steel caused by the modification of inclusions by RE are reviewed. Finally, the perspectives and trends of inclusions modified by RE elements in the steel industry are presented.

关键词： Rare earths Inclusions modification Thermodynamic calculation Properties change

Recent advances in stretchable triboelectric nanogenerators for use in wearable bioelectronic devices

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Bio-Design and manufacturing 2024年第4期7卷 566-590页

作者： Yaling wang Pengcheng Zhu Yue Sun Pan Li Yanchao mao College of Science Henan Agricultural UniversityZhengzhou 450002China Key Laboratory of materials Physics of ministry of Education School of PhysicsZhengzhou UniversityZhengzhou 450001China

wearable bioelectronic devices have the capacity for real-time human health monitoring,the provision of tailored services,and natural interaction with smart ***,these wearable bioelectronic devices rely on conventional rigid batteries that are frequently charged or replaced and are incompatible with the skin,leading to a discontinuity in complex therapeutic tasks related to human health monitoring and human-machine *** triboelectric nanogenerator(TENG)is a high-efficiency energy harvesting technology that converts mechanical into electrical energy,effectively powering wearable bioelectronic *** study comprehensively overviews recent advances in stretchable TENG for use in wearable bioelectronic *** working mechanism of stretchable TENG is initially explained.A comprehensive discussion presents the approaches for fabricating stretchable TENG,including the design of stretchable structures and the selection of stretchable ***,applications of wearable bioelectronic devices based on stretchable TENG in human health monitoring(body movements,pulse,and respiration)and human-machine interaction(touch panels,machine control,and virtual reality)are ***,the challenges and developmental trends regarding wearable bioelectronic devices based on stretchable TENG are elaborated.

关键词： Stretchable Triboelectric nanogenerators Structure Human health monitoring Human-machine interaction

Bioactive Hydrogels with Pro-coagulation Effect for Hemostasis

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Chinese Journal of Chemistry 2024年第1期42卷 87-103,I0004页

作者： Quanshi Guo Yihang Ding Lisha Yu Zongrui Tong Zhengwei mao mOE Key Laboratory of macromolecular Synthesis and Functionalization Department of Polymer Science and EngineeringZhejiang UniversityHangzhouZhejiang 310058China Department of Hepatobiliary and Pancreatic Surgery The Second Affiliated HospitalSchool of MedicineZhejiang UniversityHangzhouZhejiang 310009China Key Laboratory of Precision Diagnosis and Treatment for Hepatobiliary and Pancreatic Tumor of Zhejiang Province HangzhouZhejiang 310009China

Hemostatic hydrogels are widely applied for wound management of damaged tissues,traumatic wounds,and surgical *** hydrogels composed of bioactive components,including fibrin and thrombin,showed great promise in the clinic due to their good pro-coagulation *** the expanding knowledge of cascade reaction of blood coagulation and emerging bioactive substances,massive bioactive hydrogels consisting of peptides,hemocoagulase,polyphosphate(polyP),etc.,have been developed as effective hemostatic *** on the coagulation process and mechanism,we summarize the role of reported bioactive hydrogels in hemostasis in this *** conclude the key points in the coagulation process,including activation of coagulation factors,fibrinogen polymerization,etc.,then discuss how to design bioactive hydrogels to accelerate coagulation targeted to these ***,we conclude the progress and propose a perspective of bioactive hydrogels with a pro-coagulation effect for hemostasis.

关键词： Hemostasis Biological activity Biomaterials Enzyme catalysis Composites

Theoretical screening of cooperative N-bridged dual-atom sites for efficient electrocatalytic nitrogen reduction with remolding insight

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Nano Research 2024年第4期17卷 3413-3422页

作者： Huimei Chen Yan Yang Chi Jiao Zhiwen Zhuo Junjie mao Yan Liu Key Laboratory of Functional molecular Solids Ministry of EducationCollege of Chemistry and Materials ScienceAnhui Normal UniversityWuhu 241002China

The electrocatalytic nitrogen reduction reaction(e-NRR)is a promising alternative method for the Haber–Bosch ***,it still faces many challenges in searching for high activity,stability,and selectivity catalysts and ascertaining the catalytic mechanism with complete ***,a series of graphene-based N-bridged dual-atom catalysts(m1-N-m2/NC)are systematically investigated via first-principle calculation and a high-throughput screening *** result unveils that N_(2) adsorption on m1-N-m2/NC in bridge-on adsorption mode can effectively break the scaling relationship on single-atom catalysts(SACs).moreover,V-N-Ru/NC and V-N-Os/NC are systematically screened out as promising e-NRR catalysts,with extremely low limiting potentials of-0.20 and-0.18 V,***,the adsorption site competition between*N_(2) and*H,as well as the competitive twin reactions of hydrogen evolution reaction(HER)on intermediates(N_(n)H_(m))during the e-NRR process,is systematically evaluated to form a remodeling insight for the reactions in mechanism,and the e-NRR of new proposed dual-atom catalysts(DACs)is strategically optimized for its high-efficiency performance potential via our remolding insight in e-NRR *** work provides new ideas and insights for the design and mechanism of e-NRR catalysts and an effective strategy for rapidly screening highly efficient e-NRR catalysts.

关键词： nitrogen reduction dual-atom catalysts high-throughput screening hydrogen evolution reaction density functional theory calculations

Perturbation of autophagy pathways in murine alveolar macrophage by 2D TmDCs is chalcogen-dependent

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Journal of Environmental Sciences 2024年第1期135卷 97-107页

作者： Xiaofei Zhou weitao Jin Rui Zhang Xuan mao Jianbo Jia Hongyu Zhou College of Science&Technology Hebei Agricultural UniversityHuanghua 061100China Institute of Environmental Research at Greater Bay Area Key Laboratory for Water Quality and Conservation of the Pearl River DeltaMinistry of EducationGuangzhou UniversityGuangzhou 510006China

Increasing risks of incidental and occupational exposures to two-dimensional transition metal dichalcogenides(2D TmDCs)due to their broad application in various areas raised their public health *** the composition-dependent cytotoxicity of 2D TmDCs has been well-recognized,how the outer chalcogenide atoms and inner transition metal atoms differentially contribute to their perturbation on cell homeostasis at non-lethal doses remains to be *** the present work,we compared the autophagy induction and related mechanisms in response to wS_(2),NbS_(2),wSe_(2)and Nb Se_(2)nanosheets exposures in mH-S murine alveolar *** these 2D TmDCs had comparable physicochemical properties,overall cytotoxicity and capability in triggering autophagy in mH-S cells,but showed outer chalcogen-dependent subcellular localization and activation of autophagy ***,wS_(2)and NbS_(2)nanosheets adhered on the cell surface and internalized in the lysosomes,and triggered m TOR-dependent activation of ***,wSe_(2)and Nb Se_(2)nanosheets had extensive distribution in cytoplasm of mH-S cells and induced autophagy in an m TOR-independent ***,the 2D TmDCs-induced perturbation on autophagy aggravated the cytotoxicity of respirable benzo[a]*** findings provide a deeper insight into the potential health risk of environmental 2D TmDCs from the perspective of homeostasis perturbation.

关键词： Chalcogen group Autophagy pathway Cell function Endosomal escape Inhalation toxicity