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Langmuir-Schaefer Film Investigation and Density Functional Theory Band Gap Calculations of Calix[n]arene-Para-Aminobenzoic Acid for Drug Nanosensor Application

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Journal of wuhan University of Technology(Materials Science) 2024年第5期39卷 1311-1318页

作者： wONG Yeong Yi F L Supian A Radzwan M Musa N F N Abd karim Department of Physics Sultan Idris Education UniversityTanjong Malim 35900Malaysia Department of Chemistry Sultan Idris Education UniversityTanjong Malim 35900Malaysia

Calix[n]arenes was utilized to detect PABA,the primary sunscreen *** study investigates the interaction of calix[4]arene(C4),calix[6]arene(C6),and PABA using the Langmuir method and first-principle density functional theory(DFT).Using the Langmuir-Schaefer(LS)technique,an ultrathin film composed of calix[n]arenes and their complexes with PABA was deposited on various *** on the Langmuir study,the PABA molecule was bonded to the lower rims of both C4 and C6 with the host-guest ratio of 1:*** of the LS films formed were then characterized by ultravioletvisible spectroscopy(UV-Vis),Fourier-transform infrared spectroscopy(FTIR)and carbon,hydrogen,nitrogen,sulfur elemental analyzer(CHNS).The band gap reduction obtained in the DFT study denotes the charge transfer interaction with promising reactivity between the calix[n]arenes and *** sensing of PABA by C4 and C6 is successful based on the formation of bonding between them due to the hosts’effective trapping *** outcomes of this study could be applied to drug delivery systems for future pharmaceutical and medical applications.

关键词： calix[n]arenes band gap density functional theory Langmuir-Schaefer PABA sensor

Bidirectional rotating direct-current triboelectric nanogenerator with self-adaptive mechanical switching for harvesting reciprocating motion

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International Journal of Extreme Manufacturing 2024年第4期6卷 324-335页

作者： Donghan Lee Joonmin Chae Sumin Cho Jong woo Kim Awais Ahmad Mohammad Rezaul karim Moonwoo La Sung Jea Park Dongwhi Choi Department of Mechanical Engineering(Integrated Engineering Program) Kyung Hee University1732 Deogyeong-daeroYonginGyeonggi 17104Republic of Korea Department of Chemistry University of LahoreLahorePakistan Department of Mechanical Engineering College of EngineeringKing Saud UniversityRiyadh 11421Saudi Arabia School of Mechanical Engineering Korea University of Technology and Education1600 Chungjeol-roCheonanChungnam 31253Republic of Korea

Amid the growing interest in triboelectric nanogenerators(TENGs)as novel energy-harvesting devices,several studies have focused on direct current(DC)TENGs to generate a stable DC output for operating electronic ***,owing to the working mechanisms of conventional DC TENGs,generating a stable DC output from reciprocating motion remains a ***,we propose a bidirectional rotating DC TENG(BiR-TENG),which can generate DC outputs,regardless of the direction of rotation,from reciprocating *** distinct design of the BiR-TENG enables the mechanical rectification of the alternating current output into a rotational-direction-dependent DC ***,it allows the conversion of the rotational-direction-dependent DC output into a unidirectional DC output by adapting the configurations depending on the rotational *** to these tailored design strategies and subsequent optimizations,the BiR-TENG could generate an effective unidirectional DC *** of the BiR-TENG for the reciprocating motions of swinging doors and waves were demonstrated by harnessing this *** study demonstrates the potential of the BiR-TENG design strategy as an effective and versatile solution for energy harvesting from reciprocating motions,highlighting the suitability of DC outputs as an energy source for electronic devices.

关键词： direct-current triboelectric nanogenerator mechanical rectification self-adaptive mechanical design harvesting reciprocation motion

A New Scheme of the ARA Transform for Solving Fractional-Order waves-Like Equations Involving Variable Coefficients

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工程与科学中的计算机建模(英文) 2024年第1期138卷 761-791页

作者： Yu-Ming Chu Sobia Sultana Shazia karim Saima Rashid Mohammed Shaaf Alharthi Department of Mathematics Huzhou UniversityHuzhou313000China Department of Mathematics Imam Mohammad Ibn Saud Islamic UniversityRiyadh11461Saudi Arabia Department of Basic Sciences and Humanities UET LahoreFaisalabad Campus54800Pakistan Department of Mathematics Government College UniversityFaisalabad38000Pakistan Department of Mathematics and Statistics College of ScienceTaif UniversityP.O.Box 11099Taif21944Saudi Arabia

The goal of this research is to develop a new,simplified analytical method known as the ARA-residue power series method for obtaining exact-approximate solutions employing Caputo type fractional partial differential equations(PDEs)with variable ***-transform is a robust and highly flexible generalization that unifies several existing *** key concept behind this method is to create approximate series outcomes by implementing the ARA-transform and Taylor’s *** process of finding approximations for dynamical fractional-order PDEs is challenging,but the ARA-residual power series technique magnifies this challenge by articulating the solution in a series pattern and then determining the series coefficients by employing the residual component and the limit at infinity *** approach is effective and useful for solving a massive class of fractional-order *** appealing implementations are taken into consideration to demonstrate the effectiveness of the projected technique in creating solitary series findings for the governing equations with variable ***,several visualizations are drawn for different fractional-order *** that,the estimated findings by the proposed technique are in close agreement with the exact ***,statistical analyses further validate the efficacy,dependability and steady interconnectivity of the suggested ARA-residue power series approach.

关键词： ARA-transform Caputo fractional derivative residue-power seriesmethod analytical solutions statistical analysis

Accurate 3D Thermal Network Development for Direct-drive Outer-rotor Hybrid-PM Flux-switching Generator

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Chinese Journal of Electrical Engineering 2024年第2期10卷 80-92页

作者： Ali Zarghani Mohammad Farahzadi Aghil Ghaheri karim Abbaszadeh Faculty of Electrical Engineering Shahid Beheshti UniversityTehran ***Iran Faculty of Electrical Engineering University of Science and CultureTehran ***Iran Department of Electrical Engineering K.N.Toosi University of TechnologyTehran ***Iran

Heat and thermal problems are major obstacles to achieving high power density in compact permanent magnet(PM)***,a comprehensive,accurate,and rapid temperature rise estimation method is required for novel electric machines to ensure safe and reliable operations.A unique three-dimensional(3D)lumped parameter thermal network(LPTN)is presented for accurate thermal modeling of a newly developed outer-rotor hybrid-PM flux switching generator(OR-HPMFSG)for direct-drive ***,the losses of the OR-HPMFSG are calculated using 3D finite element analysis(FEA).Subsequently,all machine components considering the thermal contact resistance,anisotropic thermal conductivity of materials,and various heat flow paths are comprehensively modeled based on the thermal *** the proposed 3-D LPTN,internal nodes are considered to predict the average temperature as well as the hot spots of all active and passive *** measurements are performed on a prototype OR-HPMFSG to validate the efficiency of the 3-D LPTN.A comparison of the results at various operating points between the developed 3-D LPTN,experimental test,and FEA indicates that the 3-D LPTN quickly approximates the hotspot and mean temperature of all components under both transient and steady states with high accuracy.

关键词： Direct-drive wind turbine hybrid-PM flux switching generator lumped parameter thermal network temperature estimation 3D thermal modeling

Neural network-based estimation of lower limb joint kinematics:A minimally intrusive approach for gait analysis

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Medicine in Novel Technology and Devices 2024年第3期23卷 81-97页

作者： Farid Kenas Nadia Saadia Amina Ababou Noureddine Ababou Mahdi Zabat karim BenSiSaid Laboratory of Robotics Parallelism and Embedded Systems University of Science and Technology Houari Boumediene AlgiersAlgeria Laboratory of Instrumentation University of Science and Technology Houari Boumediene AlgiersAlgeria

The establishment of a quantitative gait analysis system holds paramount importance,particularly in the context of functional rehabilitation of the lower *** emphasize the imperative for sensors to be portable,compact,integrated,and non-intrusive,crucial characteristics in the rehabilitation field to facilitate their use and ensure optimal integration into care *** study investigates an innovative approach aimed at reducing the reliance on body-fixed sensors by harnessing their data within a neural network,thus concentrating on the joint kinematics of the lower *** primary objective is to estimate the flexion-extension angles of the hip,knee,and ankle during walking,utilizing data collected by two sensors positioned on the subject's ***,the neural network undergoes training with calculated data(leg tilt angles and angular velocities)sourced from the OpenSim database,followed by further refinement with experimental data obtained from a subject walking on a treadmill,wherein leg tilt angles and angular velocities are *** significance of this research is underscored by the demonstrated capability,through conducted tests,of the implemented networks to efficiently fuse data from a minimal set of ***,the proposed approach emerges as both practical and minimally intrusive,facilitating a robust evaluation of gait kinematic parameters.

关键词： Artificial neural network Joint angle Inertial measurement unit Kinematic gait analysis Treadmill

Performance Comparison of Hyper-V and KVM for Cryptographic Tasks in Cloud Computing

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Computers, Materials & Continua 2024年第2期78卷 2023-2045页

作者： Nader Abdel karim Osama A.Khashan waleed K.Abdulraheem Moutaz Alazab Hasan Kanaker Mahmoud E.Farfoura Mohammad Alshinwan Department of Intelligent Systems Faculty of Artificial IntelligenceAl-Balqa Applied UniversityAl-Salt1705Jordan Research and Innovation Centers Rabdan AcademyP.O.Box 114646Abu DhabiUnited Arab Emirates Department of Information Systems and Networks TheWorld Islamic Sciences and Education UniversityAmman11947Jordan Department of Cyber Security Isra UniversityAmman1162Jordan Faculty of Science and Information Technology Al-Zaytoonah University of JordanAmman11733Jordan Middle East University Research Unit Middle East UniversityAmman11831Jordan

As the extensive use of cloud computing raises questions about the security of any personal data stored there,cryptography is being used more frequently as a security tool to protect data confidentiality and privacy in the cloud environment.A hypervisor is a virtualization software used in cloud hosting to divide and allocate resources on various pieces of *** choice of hypervisor can significantly impact the performance of cryptographic operations in the cloud *** important issue that must be carefully examined is that no hypervisor is completely superior in terms of performance;Each hypervisor should be examined to meet specific *** main objective of this study is to provide accurate results to compare the performance of Hyper-V and Kernel-based Virtual Machine(KVM)while implementing different cryptographic algorithms to guide cloud service providers and end users in choosing the most suitable hypervisor for their cryptographic *** study evaluated the efficiency of two hypervisors,Hyper-V and KVM,in implementing six cryptographic algorithms:Rivest,Shamir,Adleman(RSA),Advanced Encryption Standard(AES),Triple Data Encryption Standard(TripleDES),Carlisle Adams and Stafford Tavares(CAST-128),BLOwFISH,and *** study’s findings show that KVM outperforms Hyper-V,with 12.2%less Central Processing Unit(CPU)use and 12.95%less time overall for encryption and decryption operations with various file *** study’s findings emphasize how crucial it is to pick a hypervisor that is appropriate for cryptographic needs in a cloud environment,which could assist both cloud service providers and end *** research may focus more on how various hypervisors perform while handling cryptographic workloads.

关键词： Cloud computing performance virtualization hypervisors Hyper-V KVM cryptographic algorithm

A comparative in vitro study on the effect of SGLT2 inhibitors on chemosensitivity to doxorubicin in MCF-7 breast cancer cells

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Oncology Research 2024年第5期32卷 817-830页

作者： SHAHID karim ALANOUD NAHER ALGHANMI MAHA JAMAL HUDA ALKREATHY ALAM JAMAL HIND A.ALKHATABI MOHAMMED BAZUHAIR AFTAB AHMAD Department of Clinical Pharmacology Faculty of MedicineKing Abdulaziz UniversityJeddahSaudi Arabia Department of Biochemistry Faculty of ScienceKing Abdulaziz UniversityJeddahSaudi Arabia Department of Biochemistry College of ScienceUniversity of JeddahJeddah21959Saudi Arabia Health Information Technology Department The Applied CollegeKing Abdulaziz UniversityJeddahSaudi Arabia Pharmacovigilance and Medication Safety Unit Center of Research Excellence for Drug Research and Pharmaceutical IndustriesKing Abdulaziz UniversityJeddahSaudi Arabia

Cancer frequently develops resistance to the majority of chemotherapy *** study aimed to examine the synergistic cytotoxic and antitumor effects of SGLT2 inhibitors,specifically Canagliflozin(CAN),Dapagliflozin(DAP),Empagliflozin(EMP),and Doxorubicin(DOX),using in vitro *** precise combination of CAN+DOX has been found to greatly enhance the cytotoxic effects of doxorubicin(DOX)in MCF-7 ***,it was shown that cancer cells exhibit an increased demand for glucose and ATP in order to support their ***,when these medications were combined with DOX,there was a considerable inhibition of glucose consumption,as well as reductions in intracellular ATP and lactate ***,this effect was found to be dependent on the dosages of the *** addition to effectively inhibiting the cell cycle,the combination of CAN+DOX induces substantial modifications in both cell cycle and apoptotic gene *** work represents the initial report on the beneficial impact of SGLT2 inhibitor medications,namely CAN,DAP,and EMP,on the responsiveness to the anticancer properties of *** underlying molecular mechanisms potentially involve the suppression of the function of SGLT2.

关键词： SGLT2 Cancer Cytotoxicity ATP Cell cycle

Geraniol alleviates cyclophosphamide-induced cardiotoxicity in mice

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Asian Pacific Journal of Tropical Biomedicine 2024年第10期14卷 427-435页

作者： Shahid karim Rasheed A.Shaik Department of Clinical Pharmacology Faculty of MedicineKing Abdulaziz UniversityJeddahSaudi Arabia Department of Pharmacology and Toxicology Faculty of PharmacyKing Abdulaziz UniversityJeddahSaudi Arabia

Objective:To explore the effect of geraniol on cyclophosphamide-induced ***:Mice were divided into five groups:the control group,the cyclophosphamide group(200 mg/kg cyclophosphamide,*** day 7),the group treated with geraniol 100 and 200 mg/kg from day 1 to day 14,along with a single dose of cyclophosphamide on day 7,and the geraniol alone group(200 mg/kg geraniol from day 1 to day 14).At the end of the study,animals were sacrificed,and blood and heart were collected and analyzed for biochemical,histopathological,and immunohistochemical ***:Treatment with 200 mg/kg geraniol significantly reduced the levels of cardiac injury markers,malondialdehyde,and inflammatory and apoptotic markers,while increasing antioxidant activities in mice with cyclophosphamide-induced ***,it remarkably alleviated histopathological aberrations in cardiac ***:Geraniol attenuates cyclophosphamide-induced cardiotoxicity via antioxidant,anti-inflammatory,and antiapoptotic effects.

关键词： Geraniol Cardiotoxicity Natural product Cyclophosphamide Inflammation Apoptosis

Comprehensive Review:Diagnosis,Classification,and Risk Factors of Peritoneal Dialysis-Associated Peritonitis

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Journal of Clinical and Nursing Research 2024年第7期8卷 1-9页

作者： Lingling Guo Sairah Abdul karim Post Graduate Centre Management&Science University40100 Shah AlamSelangorMalaysia School of Nursing Jiangsu Medical College224005 YanchengJiangsu ProvinceChina Faculty of Health and Life Sciences Management&Science University40100 Shah AlamSelangorMalaysia

Peritoneal dialysis(PD)is a predominant modality of renal replacement therapy(RRT)for individuals suffering from end-stage renal disease(ESRD).Peritoneal dialysis-associated peritonitis(PDAP)represents a frequent complication among patients undergoing PD,significantly contributing to adverse clinical *** review comprehensively examines the diagnosis,classification,and risk factors associated with PDAP,aiming to offer clinical practitioners essential guidance and a foundational framework for effective clinical management.

关键词： Research progress Risk factors Peritoneal dialysis-associated peritonitis