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采用前路和后路经肩胛下肌注射时,3.0 TMR关节成像对肩胛下肌肌腱撕裂的诊断能力

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国际医学放射学杂志 2017年第3期 361-361页

作者： J.Y.Jung w.h.jee C.w.Chun Y.S.Kim 王芳 Department of Radiology Seoul St.Mary’s HospitalCollege of Medicine The Catholic University of Korea

摘要目的比较前路和后路经肩胛下肌注射时,3.0 T MR关节成像对肩胛下肌肌腱撕裂(SCT)的诊断能力。方法167例关节镜确诊的病人被纳入研究(84例前路注射,83例后路注射)。2位专家回顾性为肩胛下肌肌腱撕裂评分。计算MR关节成像和关节镜正... 详细信息

摘要目的比较前路和后路经肩胛下肌注射时,3.0 T MR关节成像对肩胛下肌肌腱撕裂(SCT)的诊断能力。方法167例关节镜确诊的病人被纳入研究(84例前路注射,83例后路注射)。2位专家回顾性为肩胛下肌肌腱撕裂评分。计算MR关节成像和关节镜正确分级的比例,进行回顾性误差分析。结果前路注射时,专家1诊断敏感度为80%(24/30),特异度为72%(39/54);专家2诊断敏感度为73%(22/30),特异度为76%(41/54)。后路注射时,专家1诊断敏感度为86%(30/35),特异度为79%(38/48);专家2诊断敏感度为80%

关键词：肩胛下肌后路诊断能力关节运动器官肌腱前路 TMR

软组织良恶性肿瘤鉴别:在3.0T标准MR成像序列中附加定性和定量的扩散成像序列

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国际医学放射学杂志 2016年第3期 324-324页

作者： S.Y.Lee w.h.jee J.Y.Jung M.Y.Park S.K.Kim C.K.Jung 蓝星 Department of Radiology Seoul St.Mary’s HospitalCollege of MedicineThe Catholic University of Korea

摘要目的了解3.0 T MRI基础上增加DwI来鉴别软组织肿瘤良恶性的优势。方法回顾性分析63例因软组织肿瘤而手术的病人,均行3.0 T MRI及DwI。2位专家独立阅片,按照两步法分析肿瘤的恶性度:(1)标准MRI;(2)标准MRI联合定量及定性DwI。结果 6... 详细信息

摘要目的了解3.0 T MRI基础上增加DwI来鉴别软组织肿瘤良恶性的优势。方法回顾性分析63例因软组织肿瘤而手术的病人,均行3.0 T MRI及DwI。2位专家独立阅片,按照两步法分析肿瘤的恶性度:(1)标准MRI;(2)标准MRI联合定量及定性DwI。结果 63例肿瘤中有34例为恶性,29例为良性。在定性分析中,与良性肿瘤相比,DwI上恶性肿瘤信号高于骨骼肌更常见(P=0.003)。在定量分析中,恶性肿瘤

关键词：成像序列 DwI 软组织肿瘤良恶性 MR

Mass forming chronic pancreatitis mimicking pancreatic cystic neoplasm: A case report

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world Journal of Gastroenterology 2018年第2期24卷 297-302页

作者： Keum Nahn jee Department of Radiology Dankook University Hospital

Mass forming chronic pancreatitis is very rare. Diagnosis could be done by the pathologic findings of focal inflammatory fibrosis without evidence of tumor in pancreas. A 34-year-old man presented with right upper abdominal pain for a few weeks and slightly elevated bilirubin level on clinical findings. Radiological findings of multidetector-row computed tomography, magnetic resonance(MR) imaging with MR cholangiopancreatography and endoscopic ultrasonography revealed focal branch pancreatic duct dilatation with surrounding delayed enhancing solid component at uncinate process and head of pancreas, suggesting branch duct type intraductal papillary mucinous neoplasm. Surgery was done and pathology revealed the focal chronic inflammation, fibrosis, and branch duct dilatation. herein, I would like to report the first case report of mass forming chronic pancreatitis mimicking pancreatic cystic neoplasm.

关键词： Chronic pancreatitis Pseudotumor Computed tomography Magnetic resonance imaging Endoscopic ultrasound

Global Perspectives:The COVID-19 Pandemic in 2020−2021 and Beyond

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China CDC weekly 2021年第7期3卷 142-143页

作者： Youngmee jee Institut Pasteur Korea the whO COVID-19 IhR Emergency Committee whO R&D

while coronavirus disease 2019(COVID-19)cases have reached 100 million across the globe with more than 2 million deaths as at January 26,2021,over 50 countries have initiated vaccinations against the *** began within a year from January 12,2020,when the China CDC shared the new virus genomic sequence with the world health Organization(whO)and globally.

关键词： vaccination globally initiated

Comparison of Measurements for Enhanced Diffusion Problem in Chemical Reaction Systems

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Chinese Journal of Chemistry 2024年第14期42卷 1659-1664页

作者： Ah-Young jee Ziyang wen huan wang Beijing National Laboratory for Molecular Sciences College of Chemistry and Molecular EngineeringBeijing Key Laboratory of Polymer Chemistry&Physics of Ministry of EducationPeking UniversityBeijing100871 China

The problem of molecular diffusion in the soup of chemical reactions attracts mounting interest across fields ranging from chemistry to biophysics to material *** reactions involve bond breakup and formation,whose time scale is typically on the orders of fs to ps,while molecular diffusion occurs at time scales ofμs to *** two processes are often considered orthogonal,given the vastly different *** serial results show that the enzyme's diffusion is enhanced in a substrate-dependent manner,which was further extended to small molecule reaction systems,challenging this classical ***,the results from different groups using different techniques do not quantitatively agree,and a general mechanism is yet to be *** summarize experimental studies on diffusion problems and seek to reconcile the interpretation with understanding the limits of measurement tools and the chemical nature of reaction *** molecular diffusion in chemical reactions will provide fresh thoughts in designing chemical systems such as molecular machines that harvest work at the nanoscale in a controllable manner.

关键词： Molecular diffusion Chemical reactions Enzyme reactions Active matter Diffusion measurements Single-molecule studies Fluorescence Time-resolved spectroscopy

SeSaMe PS Function:Functional Analysis of the whole Metagenome Sequencing Data of the Arbuscular Mycorrhizal Fungi

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Genomics, Proteomics & Bioinformatics 2020年第5期18卷 613-623页

作者： jee Eun Kang Antonio Ciampi Mohamed hijri Institut de Recherche en Biologie Vegetale Departement de Sciences BiologiquesUniversite de MontrealQC H1X 2B2Canada Department of Epidemiology Biostatistics and Occupational HealthMcGill UniversityMontrealQC H3A 1A2Canada Creative Research Initiatives Center for Molecular Biology of Translation School of Life SciencesKorea UniversitySeoul 02841Republic of Korea African Genome Center AgroBioSciencesMohammed Ⅳ Polytechnic University(UM6P)43150 Ben GuerirMorocco

In this study,we introduce a novel bioinformatics program,Spore-associated Symbiotic Microbes Position-specific Function(SeSaMe PS Function),for position-specific functional analysis of short sequences derived from metagenome sequencing data of the arbuscular mycorrhizal *** unique advantage of the program lies in databases created based on genus-specific sequence properties derived from protein secondary structure,namely amino acid usages,codon usages,and codon contexts of 3-codon DNA *** PS Function searches a query sequence against reference sequence database,identifies 3-codon DNA 9-mers with structural roles,and creates a comparative dataset containing the codon usage biases of the 3-codon DNA 9-mers from 54 bacterial and fungal *** program applies correlation principal component analysis in conjunction with K-means clustering method to the comparative dataset.3-codon DNA 9-mers clustered as a sole member or with only a few members are often structurally and functionally distinctive sites that provide useful insights into important molecular *** program provides a versatile means for studying functions of short sequences from metagenome sequencing and has a wide spectrum of *** PS Function is freely accessible at ***.

关键词： SeSaMe Spore-associated symbiotic microbes Position-specific function Outlier Metagenome

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SeSaMe:Metagenome Sequence Classification of Arbuscular Mycorrhizal Fungi-associated Microorganisms

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Genomics, Proteomics & Bioinformatics 2020年第5期18卷 601-612页

作者： jee Eun Kang Antonio Ciampi Mohamed hijri Institut de Recherche en Biologie Vegetale Departement de Sciences BiologiquesUniversite de MontrealMontrealQC H1X 2B2Canada Department of Epidemiology Biostatistics and Occupational HealthMcGill UniversityMontrealQC H3A 1A2Canada Creative Research Initiatives Center for Molecular Biology of Translation School of Life SciencesKorea UniversitySeoul 02841Republic of Korea African Genome Center Agro BioSciencesMohammed Ⅵ Polytechnic University(UM6P)43150 Ben GuerirMorocco

Arbuscular mycorrhizal fungi(AMF)are plant root symbionts that play key roles in plant growth and soil *** are obligate biotrophic fungi that form coenocytic multinucleated hyphae and *** studies have shown that diverse microorganisms live on the surface of and inside their mycelia,resulting in a metagenome when whole-genome sequencing(wGS)data are obtained from sequencing AMF cultivated in *** metagenome contains not only the AMF sequences,but also those from associated *** this study,we introduce a novel bioinformatics program,Spore-associated Symbiotic Microbes(SeSaMe),designed for taxonomic classification of short sequences obtained by next-generation DNA sequencing.A genus-specific usage bias database was created based on amino acid usage and codon usage of a three consecutive codon DNA 9-mer encoding an amino acid trimer in a protein secondary *** program distinguishes between coding sequence(CDS)and non-CDS,and classifies a query sequence into a genus group out of 54 genera used as *** mean percentages of correct predictions of the CDS and the non-CDS test sets at the genus level were 71% and 50% for bacteria,68% and 73% for fungi(excluding AMF),and 49% and 72% for AMF(Rhizophagus irregularis),*** provides not only a means for estimating taxonomic diversity and abundance but also the gene reservoir of the reference taxonomic groups associated with ***,it enables users to study the symbiotic roles of associated *** can also be applicable to other microorganisms as well as soil *** is freely available at ***.

关键词： SeSaMe Spore-associated symbiotic microbes Arbuscular mycorrhizal fungi Taxonomic classification 3-codon DNA 9-mer

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Structure-activity relationship of lysophosphatidylcholines in hL-60 human leukemia cells

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Acta Pharmacologica Sinica 2004年第11期 137-140页

作者： Eun-hee LEE,jee h JUNG,Dong-soon IM Laboratories of Pharmacology and Marine Natural Product Laboratories of Pharmacology and Marine Natural Product Laboratories of Pharmacology and Marine Natural Product College of Pharmacy Pusan National University Busan 609-735 Korea College of Pharmacy Pusan National University Busan 609-735 Korea College of Pharmacy Pusan National University Busan 609-735 Korea

AIM: To explore the structure-activity relationship of lysophosphatidylcholine (LPC) and lysolipid molecules from a marine sponge and ladybirds. METhODS: we tested three synthetic LPCs and four natural lysolipids on Ca2+ mobilization in hL-60 human leukemia cells. RESULTS: we observed lysolipid-mediated Ca2+ mobilization. The activity was the same in both ester- and ether-linked lysolipids, and introduction of a double bond or methoxy group on the alkyl chain did not significantly modulate the activity. however, replacement of trimethylammonium moiety in the choline structure with ammonium moiety reduced the activity. Furthermore, change of the alkyl chain length influenced the Ca2+ response. CONCLUSION: LPC-induced Ca2+ mobilization might be dependent on the length of alkyl chain and the presence of choline moiety in hL-60 leukemia cells.

关键词： lysophosphatidylcholines leukemia calcium signaling structure-activity relationship platelet activating factor

Erratum:Author’s research-fund support notation *** forming chronic pancreatitis mimicking pancreatic cystic neoplasm:A case report world J Gastroenterology 2018;Jan 14;24(2):(297-302)

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world Journal of Gastroenterology 2021年第46期27卷 8031-8032页

作者： Keum Nahn jee Department of Radiology Dankook University HospitalCheonan 31116ChungnamSouth Korea

Correction to"Mass forming chronic pancreatitis mimicking pancreatic cystic neoplasm:A case report"world J Gastroenterology 2018;24(2):*** article had accidentally omitted the fact of research-fund support *** should ... 详细信息

关键词： Correction Supported by Research fund