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Male contraception:prospects for the new millennium

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Asian Journal of Andrology 2000年第1期2卷 3-12页

作者： w.M.Hair f.C.w.wu Department of Medicine University of Manchester Manchester MI3 9WL UKDepartment of Medicine University of Manchester Manchester MI3 9WL UK

Effective regulation of human fertility has global consequences in terms of resource depletion, pollution and pover-ty. Current family planning services predominantly target a female clientele with few significant developments in malefertility regulation for over a century. The last two decades have witnessed a gathering interest, initially from the scien-tific community, and laterally from industry, in the development of safe, reliable, reversible methods of contraceptionfor men. This review summarises the methods of male fertility regulation which are currently available and critically ex-amines the published data on novel developments in male hormonal contraception which offer the potential of improvedcontraceptive choice for all in new millennium. (Asian J Androl 2000; 2: 3 - 12)

关键词： contraception male contraceptive agents male contraceptive devices gonadotropins testosterone androgen

Synthesis and Ex Situ Doping of ZnTe and ZnSe Nanostructures with Extreme Aspect Ratios

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Nano Research 2009年第12期2卷 931-937页

作者： Joanne w.L.Yim Deirdre Chen Gregory f.Brown Junqiao wu Department of Materials Science and Engineering University of CaliforniaBerkeleyCA 94720USA Materials Sciences Division Lawrence Berkeley National LaboratoryBerkeleyCA 94720USA

we report synthesis windows for growth of millimeter-long ZnTe nanoribbons and ZnSe nanowires using vapor *** tuning the local conditions at the growth substrate,high aspect ratio nanostructures can be synthesized.A Cu-ion immersion doping method was applied,producing strongly p-type conduction in ZnTe and ionic conduction in *** extreme aspect ratio wide-bandgap semiconductors have great potential for high density nanostructured optoelectronic circuits.

关键词： Aspect ratio doping nanowires zinc selenide zinc telluride

RockSL:an integrated rock spectral library for better global shared services

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Big Earth Data 2023年第1期7卷 191-211页

作者： B.S.Xie S.Y.Zhou L.X.wu w.f.Mao w.wang Department of Surveying Mapping and Remote Sensing ScienceSchool of Geosciences and Info-PhysicsCentral South UniversityChangshaChina Laboratory of Geo-Hazards Perception Cognition and PredicationCentral South UniversityChangshaChina

Spectral data of different rocks and minerals usually show different waveforms and absorption characteristics in visible and infrared wavelengths,which allow identification of mineral species and ***,massive spectra of rock/mineral on earth surface were scattered across a variety of spectral libraries world-wide,exhibiting inconsistent data structures and measurement *** advance the data interoperability and the data usability,we collected data and information from six shared libraries with different format and measured field specimen in laboratory to establish an integrated rock spectral library(RockSL).Both the data quality of spectral curves and the integrity of descrip-tive metadata are considered in the integrated RockSL to be pub-lished in GitHub open-source *** contains not only the big spectral dataset of rocks and minerals for data service(*** sharing and retrieval)and geological discrimination,but also the characteristics dataset of key parameters/metadata(*** size,mineral composition and full-band signature,etc.)for explora-tion of data mining and knowledge *** hope that more researchers will join to improve the availability and practical value of RockSL for remote sensing *** article introduces the database structure and data processing workflow,and demon-strates a matching service and several examples of characteristic datasets of RockSL.

关键词： Rocks and minerals data interoperability integrated library geological discrimination characteristic datasets

SUPERPLASTICITY AND DIffUSION BONDING Of IN718 SUPERALLOY

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Acta Metallurgica Sinica(English Letters) 2007年第4期20卷 307-312页

作者： w.B. Han K.f. Zhang B. wang D.Z. wu School of Materials Science and Engineering Harbin Institute of Technology Harbin 150001 China

The superplasticity and diffusion bonding of IN718 superalloy were studied in this article. The strain rate sensitivity index m was obtained at different temperatures and various initial strain rates using the tensile speed mutation method; m reached its maximum value 0.53 at an initial strain rate of 1×10^-4s^-1 at 1253K. The diffusion bonding parameters, including the bonding temperature T, pressure p, and time t, affected the mechanism of joints. when the bonded specimen with 25μm thick nickel foil interlayer was tensile at room temperature, the shear fracture of the joints with nickel foil interlayer took place at the IN718 part. Microstructure study was carried out with the bonded samples. The microstructure shows an excellent bonding at the interfaces. The optimum parameters for the diffusion bonding are： T = 1273-1323K, p = 20-30MPa, t = 45-60min.

关键词： superplasticity diffusion bonding nickel foil IN718 alloy

Effects of ginsenoside Rg1 and insulin-like growth factor-Ⅰon 6-OHDA-induced neurotoxicity in SK-N-SH cells

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Effects of ginsenoside Rg1 and insulin-like growth factor-Ⅰ...

Progress in research of liver surgery in China

2012国际生理学学术大会

作者： Yan Z. wu L. Xue D.D. Chen w.f. Department of Physiology Medical College of Qingdao University

＜正＞Both ginsenoside Rg1 and insulin-like growth factor-I（IGf-I） has been reported to exert neurotropic and neuroprotective effects on the nervous *** present study was designed to investigate the neuroprotective effects of Rgl,IGf-I or Rg1 combined with IGf-I on 6-OHDA-induced neurotoxicity in SK-N-SH *** with Rgl or IGf-I significantly increased the cell viability against 6-OHDA-induced *** Rgl or IGf-I could attenuate 6-OHDA-induced decrease in mitochondrial membrane potential.6-OHDA-induced up-regulation of Bax protein expression could be restored by Rgl or IGf-I treatment. Cotreatment with Rgl and IGf-I resulted in an enhancement of cell *** results suggest that ginsenoside Rgl and IGf-I have neuroprotective effects against 6-OHDA-induced apoptosis in SK-N-SH *** with Rgl and IGf-I have synergistic effect on cell survival in SK-N-SH cells.

关键词： ginsenoside Rg1 6-OHDA SK-N-SH cells insulin-like growth factor-Ⅰ

来源： cnki会议评论

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world Journal of Gastroenterology 2000年第6期6卷 773-776页

作者： wu MC Shen f Second Mil Med Univ Eastern Hepatobiliary Surg Hosp Shanghai 200438 Peoples R China

INTRODUCTIONLiver surgery,was started in the late 1950s in Chinaand has developed rapidly in the past 40 *** study on the diagnosis and treatment of primaryliver cancer in China underwent four stages:①Inthe 1950s,the... 详细信息

关键词： liver neoplasms/surgery liver transplantation liver neoplasms/diagnosis liver neoplasms/therapy biopsy needle genes suppressor tumor

Parameter-free Shifted Laplacian Reconstruction for Multiple Kernel Clustering

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IEEE/CAA Journal of Automatica Sinica 2024年第4期11卷 1072-1074页

作者： Xi wu Zhenwen Ren f.Richard Yu the School of National Defence Science and Technology Southwest University of Science and TechnologyMianyang 621010China the School of National Defence Science and Technology Southwest University of Science and TechnologyMianyang 621010 the Guangxi Key Laboratory of Machine Vision and Intelligent Control Wuzhou UniversityWuzhou 543002 the Guangdong Laboratory of Artificial Intelligence and Digital Economy(SZ) Shenzhen 518060China

Dear Editor,This letter proposes a parameter-free multiple kernel clustering(MKC)method by using shifted Laplacian *** MKC can effectively cluster nonlinear data,but it faces two main challenges:1)As an unsupervised method,it is up against parameter problems which makes the parameters intractable to tune and is unfeasible in real-life applications;2)Only considers the clustering information,but ignores the interference of noise within Laplacian.

关键词： parameter letter Parameter

Genome-wide association studies for inflorescence type and remontancy in Hydrangea macrophylla

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Horticulture Research 2020年第1期7卷 2477-2485页

作者： Xingbo wu Lisa w.Alexander Oak Ridge Institute of Science and Technology Otis L.Floyd Nursery Research Center472 Cadillac LaneMcMinnvilleTNUSA U.S.Department of Agriculture Agricultural Research ServiceU.S.National ArboretumFloral and Nursery Plants Research UnitOtis L.Floyd Nursery Research Center472 Cadillac LaneMcMinnvilleTNUSA

Inflorescence type and remontancy are two valuable traits in bigleaf hydrangea(Hydrangea macrophylla L.)and both are recessively *** marker-assisted selection(MAS)can greatly reduce the time necessary to breed cultivars with desired *** this study,a genome-wide association study(GwAS)using 5803 single-nucleotide polymorphisms(SNPs)was performed using a panel of 82 bigleaf hydrangea *** SNP locus(Hy_CAPS_Inflo)associated with inflorescence type was identified with general linear model(GLM)and mixed linear model(MLM)methods that explained 65.5%and 36.1%of the phenotypic variations,***-three SNPs associated with remontancy were detected in GLM whereas no SNP was detected in *** SNP locus(Hy_CAPS_Inflo)was converted to a cleaved amplified polymorphic sequence(CAPS)marker that showed absolute identification accuracy(100%)of inflorescence type in a validation panel consisting of eighteen *** *** SNP was investigated in 341 f1 progenies using genotyping by sequencing(GBS)and co-segregated with inflorescence type(χ^(2)=0.12;P=0.73).The SNP was subsequently used for breeding selection using kompetitive allele specific PCR(KASP)*** directions for the use of genomics and MAS in hydrangea breeding improvement are *** results presented in this study provide insights for further research on understanding genetic mechanisms behind inflorescence type and remontancy in *** CAPS and KASP markers developed here will be immediately useful for applying MAS to accelerate breeding improvement in hydrangea.

关键词： breeding cultivar CAPS

On the formation of shear bands in a metallic glass under tailored complex stress fields

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Journal of Materials Science & Technology 2020年第18期52卷 112-117页

作者： S.H.Chen T.Li w.J.Chang H.D.Yang J.C.Zhang H.H.Tang S.D.feng f.f.wu Y.C wu School of Mechanical Engineering Hefei University of TechnologyHefei 230009China State Key Laboratory of Metastable Materials Science and Technology Yanshan UniversityQinhuangdao 066004China School of Materials Science and Engineering Liaoning University of TechnologyJinzhou 121001China School of Materials Science and Engineering Hefei University of TechnologyHefei 230009China

The formation of shear bands in metallic glasses(MGs)was examined by tailoring localized complex stress fields(LCSfs).The findings have shown that the LCSfs in MGs can increase the localization of strained atoms and accelerate the release of accumulated deformation energy for initiating a shear band in confined and thin-layered *** findings not only add more knowledge to the formation mechanisms of shear bands in MGs,but also provide possible rationale for the discrepancies in the mechanical properties of different-sized *** compared with the bulk samples,the higher strength and larger elastic limits in nanoscaled MGs could be attributed to the elimination of stress-concentrators,which can serve as LCSfs.

关键词： Localized complex stress field Shear band Metallic glass Molecular dynamics simulation Size effect