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Integration of 1h.NMR-Based Metabolomics Approach.w.th.Traditional Ch.nese Pulse Diagnosis to Evaluate th. Qi-Enh.ncing Activity of h.rbal Tea

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Ch.nese Medicine 2024年第3期15卷 49-74页

作者： Ch.a-h.in Lin Po-Jung h.ang chung-h.uan w.ng Mo-Rong Xu Sh.ng-Yang w.ng Department of Forestry Chung Hsing University Taichung Fu Kang Traditional Ch.nese Medicine Clinic Nantou Special Crop and Metabolome Discipline Cluster Academy Circle Economy Chung Hsing University Taichung Agricultural Biotech.ology Research.Institute Academia Sinica Taipei City

h.man metabolism is intricately linked to an individual’s h.alth.status. Regardless of living h.bits, it w.ll be reflected in th. metabolic ch.racteristics of urine. Th. utilization of th. 1h.NMR-based metabolomics meth.d h.s enabled examine th. metabolomic ch.nges in urine under various ph.siology conditions, providing valuable insigh.s into metabolites. In th.s particular study, volunteers w.re divided into tw. groups based on th. strength.of th.ir spleen pulses, using th. pulse diagnosis meth.d employed in traditional Ch.nese medicine. Subsequently, th.ir urine samples w.re analyzed, revealing notable variances in urea, creatinine, citric acid, succinic acid, trimeth.lamine-N-oxide (TMAO), alanine, h.ppuric acid, and glycine betw.en th. tw. groups. Interestingly, individuals w.th.w.ak spleen pulses sh.w.d significant improvements after consuming h.rbal tea. Furth.rmore, w. conducted LC-MS analysis on h.rbal tea and performed adenosine triph.sph.te (ATP) activity tests on th. C2C12 mouse skeletal muscle cell line. Th. results indicated th.t w.th.n a reasonable concentration range, exposure to h.rbal tea led to an increase in th. mitoch.ndrial ATP production capacity of C2C12 cells. Th.se findings sh.d ligh. on th. relationsh.p betw.en traditional Ch.nese medicine pulse diagnosis and urine metabolites, h.gh.igh.ing th.ir potential as non-invasive and straigh.forw.rd h.alth.assessment indicators. Th.y can aid in th. preliminary determination of necessary dietary and lifestyle ch.nges to enh.nce overall bodily h.alth.

关键词： 1h.NMR Metabolomics Traditional Ch.nese Pulse Diagnosis Qi-Enh.ncing h.rbal Tea

Ocular image-based deep learning for predicting refractive error:A systematic review

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Advances in Oph.h.lmology Practice and Research 2024年第3期4卷 164-172页

作者： Samanth. Min Er Yew.Yibing Ch.n Jocelyn h.i Lin Goh.David Ziyou Ch.n Marcus Ch.n Jin Tan Ch.ng-Yu Ch.ng Victor Teck Ch.ng Koh.Yih.chung Th.m Department of Oph.h.lmology Yong Loo Lin School of MedicineNational University of SingaporeSingapore Centre for Innovation and Precision Eye h.alth Yong Loo Lin School of MedicineNational University of SingaporeSingapore Sch.ol of Ch.mistry Chemical Engineeringand BiotechnologyNanyang Technological UniversitySingapore Singapore Eye Research.Institute Singapore National Eye CentreSingapore Department of Oph.h.lmology National University HospitalSingapore Oph.h.lmology and Visual Sciences(Eye ACP) Duke-NUS Medical SchoolSingapore

ackground:Uncorrected refractive error is a major cause of vision impairment w.rldw.de and its increasing prevalent necessitates effective screening and management ***,deep learning,a subset of Artificial Intelligence,h.s significantly advanced oph.h.lmological diagnostics by automating tasks th.t required extensive clinical *** recent studies h.ve investigated th. use of deep learning models for refractive pow.r detection th.ough.various imaging tech.iques,a compreh.nsive systematic review.on th.s topic is h.s yet be *** review.aims to summarise and evaluate th. performance of ocular image-based deep learning models in predicting refractive *** text:w. search.on th.ee databases(PubMed,Scopus,w.b of Science)up till June 2023,focusing on deep learning applications in detecting refractive error from ocular *** included studies th.t h.d reported refractive error outcomes,regardless of publication *** systematically extracted and evaluated th. continuous outcomes(sph.re,SE,cylinder)and categorical outcomes(myopia),ground truth.measurements,ocular imaging modalities,deep learning models,and performance metrics,adh.ring to PRISMA *** studies w.re identified and categorised into th.ee groups:retinal ph.to-based(n=5),OCT-based(n=1),and external ocular ph.to-based(n=3).For h.gh.myopia prediction,retinal ph.to-based models ach.eved AUC betw.en 0.91 and 0.98,sensitivity levels betw.en 85.10%and 97.80%,and specificity levels betw.en 76.40%and 94.50%.For continuous prediction,retinal ph.to-based models reported MAE ranging from 0.31D to 2.19D,and R^(2) betw.en 0.05 and *** OCT-based model ach.eved an AUC of 0.79–0.81,sensitivity of 82.30%and 87.20%and specificity of 61.70%–68.90%.For external ocular ph.to-based models,th. AUC ranged from 0.91 to 0.99,sensitivity of 81.13%–84.00%and specificity of 74.00%–86.42%,MAE ranges from 0.07D to 0.18D and accuracy ranges from 81.60%to 96.70%.Th. reported papers colle

关键词： Deep Learning Artificial Intelligence Refractive Error Retinal images Optical Coh.rence Tomograph. Ph.torefraction Ocular images Prediction

Th. use of h.drogel microsph.res as cell and drug delivery carriers for bone,cartilage,and soft tissue regeneration

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Biomaterials Translational 2024年第3期5卷 236-256页

作者： chung-h.un Lin Jesse RSrioudom w.i Sun Malcolm Xing Su Yan Le Yu Jian Yang Department of Biomedical Engineering The Pennsylvania State UniversityUniversity ParkPAUSA Department of Bioengineering University of PennsylvaniaPhiladelphiaPAUSA Leicester International Institute Dalian University of TechnologyPanjinLiaoning ProvinceChina Department of Mech.nical Engineering University of ManitobaWinnipegCanada Division of Biological and Biomedical Systems University of Missouri-Kansas CityKansas CityMOUSA Biomedical Engineering Program Westlake UniversityHangzhouZhejiang ProvinceChina Research.Centre for Industries of th. Future Westlake UniversityHangzhouZhejiang ProvinceChina

Bone,cartilage,and soft tissue regeneration is a complex process involving many cellular activities across various cell *** remain th.“gold standard”for th. regeneration of th.se ***,th. use of autografts is associated w.th.many disadvantages,including donor scarcity,th. requirement of multiple surgeries,and th. risk of *** development of tissue engineering tech.iques opens new.avenues for enh.nced tissue ***,th. expectations of tissue engineering scaffolds h.ve gone beyond merely providing ph.sical support for cell *** scaffolds sh.uld also provide biological cues to actively boost tissue *** a new.type of injectable biomaterial,h.drogel microsph.res h.ve been increasingly recognised as promising th.rapeutic carriers for th. local delivery of cells and drugs to enh.nce tissue *** to traditional tissue engineering scaffolds and bulk h.drogel,h.drogel microsph.res possess distinct advantages,including less invasive delivery,larger surface area,h.gh.r transparency for visualisation,and greater flexibility for ***,w. review.th. materials ch.racteristics of h.drogel microsph.res and compare th.ir fabrication approach.s,including microfluidics,batch.emulsion,electroh.drodynamic spraying,lith.graph.,and mech.nical ***,based on th. different requirements for bone,cartilage,nerve,skin,and muscle tissue regeneration,w. summarize th. applications of h.drogel microsph.res as cell and drug delivery carriers for th. regeneration of th.se ***,h.drogel microsph.res are regarded as effective th.rapeutic delivery carriers to enh.nce tissue regeneration in regenerative ***,significant effort is required before h.drogel microsph.res become w.dely accepted as commercial products for clinical use.

关键词： drug delivery fabrication tech.iques h.drogel microsph.res microgels tissue regeneration

中学生领导力培养现状与优化策略研究 ——以马来西亚华文独中K中学为例

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中学生领导力培养现状与优化策略研究 ——以马来西亚华文独中K中...

作者：彭忠祥（Pang chung Seong）华东师范大学

学位级别：硕士

随着2018年《马来西亚华文独中教育大蓝图》的颁布,提升了独中老师对中学生领导力培养的广泛关注。中学生领导力培养策略的优化,是为马来西亚独中教师勾勒出培养学生具备领导素养、领导行为及领导技能的过程,它是学生发展核心素养的路径... 详细信息

随着2018年《马来西亚华文独中教育大蓝图》的颁布,提升了独中老师对中学生领导力培养的广泛关注。中学生领导力培养策略的优化,是为马来西亚独中教师勾勒出培养学生具备领导素养、领导行为及领导技能的过程,它是学生发展核心素养的路径,也是“21世纪技能”中所强调的育人目标。研究证明,中学生领导力培养策略的优化是提升中学生领导力的关键。然而,中学生领导力培养现状无法给予对学生综合素养带来积极的发展。现有关于中学生领导力培养现状与优化策略的研究文献,有的着重于理论构建,有的则针对特定群体进行案例研究,不过对马来西亚华文独中学生领导力培养的案例样本称得上是绝无仅有。以马来西亚中学生领导力框架为基准,我们须要思考:当前华文独立中学对学生领导力的开发与培养已有哪些具体的行动策略,有哪些不足之处,须要改进与完善的具体内容来保障优化策略的有效推进。本文采用质性研究,通过文献梳理、问卷调查及访谈法,对吉隆坡K中学学生领导力培养现阶段的实施情况展开调研,综合地把握中学生领导力培养的内在本质,进而探析学生领导力培养中的问题与成因。通过对典型学校案例的研究分析以及与受访者的访谈内容分析,本人发现:K中学在中学生领导力培养开发与管理上缺乏有系统的课程规划、资源管理结构不完善的问题。针对上述问题,本研究以中学生领导力模型与课程发展理论为切入点,提出中学生领导力培养的优化策略,通过有系统地管理来提高中学生领导力培养效能,具体为:第一,构建完善的中学生领导力培养课程;第二,统整家校社区资源,促进学生领导力的发展和提高学生综合素质;第三,建立以能力发展为导向的领导人才梯队。

关键词：中学生领导力培养课程开发资源管理

Petroleum h.teroatom compounds in various commercial delayed coking liquids： ch.racterized by FT-ICR MS and GC tech.iques

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Science Ch.na Ch.mistry 2017年第2期60卷 284-292页

作者： Miao h. Ch.ang Guo Linzh.u Zh.ng Suoqi Zh.o Keng h. chung Ch.nming Xu Quan Sh. State Key Laboratory of h.avy Oil Processing China University of Petroleum Beijing 102249 China Daqing Oilfield Limited Corporation Daqing 163159 China North.h.ajin Ch.mical Industries Group Corporation Panjin 124000 China

Delayed coking is an important petroleum resid conversion *** processability of coking liquids is know. to be dependent on th. h.teroatom compounds present in th. coking *** commercial delayed coking liquids w.re ch.racterized by electrospray ionization(ESI)Fourier transform ion cyclotron resonance mass spectrometry(ESI FT-ICR MS)and gas ch.omatograph.c *** relatively abundant h.teroatom compounds in th. coking liquids w.re 1-4 aromatic-ring pyridinic nitrogen compounds,carbazoles,benzocarbazoles,ph.nols,mercaptans,benzoth.oph.nes,dibenzoth.oph.nes,and *** liquids derived from various feeds h.d similar compound class types,molecular w.igh. distribution ranges,and double bond equivalents(DBE).h.w.ver,th. concentration of individual compounds and th. distribution of DBE versus carbon number of h.teroatom compounds varied.A comparison of h.teroatom compounds in coker feeds and products revealed th. various reaction mech.nism of h.teroatom compounds occurred during th. coking *** results suggested th.t molecular-level process models can be developed for optimization of unit operation to obtain desirable products th.t meet th. environmental specifications and quality requirements.

关键词： FT-ICR MS molecular composition h.teroatom compounds petroleum delayed coking

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对战国儒家“金声玉振”概念的本体诠释

哲学分析 2024年第4期15卷 43-56,197页

作者：刘星鼎成中英澳大利亚新南威尔士大学哲学系美国夏威夷大学哲学系

“金声玉振”概念共现于《五行》与《孟子》,但学界目前对于此概念所包含的战国儒家共同的思想“本体”没有透彻的观照。如果尝试引入“本体诠释学”的方法,并对该方法进行分析检讨,将其自觉地运用于概念与概念史的诠释,有助于廓清“金... 详细信息

“金声玉振”概念共现于《五行》与《孟子》,但学界目前对于此概念所包含的战国儒家共同的思想“本体”没有透彻的观照。如果尝试引入“本体诠释学”的方法,并对该方法进行分析检讨,将其自觉地运用于概念与概念史的诠释,有助于廓清“金声玉振”概念的相关争论,探索其背后更广阔的诠释空间。“金声玉振”以“玉振”收束、统摄并超越“金声”,表明《五行》《孟子》各自都对先秦儒家德性进行整合,以呈显儒学的“天道”或“圣道”内涵。进而,“金声玉振”以“金声”为始,“玉振”却没有终点。此比喻于人的道德修养而言,意味着天道本体在人身上具体化为内在“仁”德本性的自觉、培养、实践过程,且因人内在主体的创造性和经验世界的无限性,最终指向生生不已天道本体的无限展开、丰富与涌流。

关键词：金声玉振本体诠释战国儒家圣道仁

Tendency to Avoid Ph.sical Activity and Sport:Associations w.th.w.igh. Stigma,and Psych.logical Distress in a Tw.-w.ve Longitudinal Study

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International Journal of Mental h.alth.Promotion 2024年第8期26卷 633-641页

作者： Saffari Moh.en Yi-Ch.ng Lin Po-Ch.ng h.ang Yu-Ting h.ang Ru-Yi h.ang Ch. h.ien h.ang Jung-Sh.ng Ch.n w.i Ch.en Poon Mark D.Griffith. chung-Ying Lin h.alth.Research.Center Life Style InstituteBaqiyatallah University of Medical SciencesTehran***Iran h.alth.Education Department Faculty of HealthBaqiyatallah University of Medical SciencesTehran***Iran Department of Early Ch.ldh.od and Family Education National Taipei University of EducationTaipei106TaiwanChina Sch.ol of Ph.sical Th.rapy Graduate Institute of Rehabilitation ScienceCollege of MedicineChang Gung UniversityTaoyuan333TaiwanChina Institute of Allied h.alth.Sciences College of MedicineNational Cheng Kung UniversityTainan701TaiwanChina Division of Family Medicine Taipei Tzu Chi HospitalBuddhist Tzu Chi Medical Foundationand School of MedicineTzu Chi UniversityHualienTaiwanChina Data Science Degree Program National Taiwan University and Academia SinicaTaipeiTaiwanChina Department of Family Medicine and Community Medicine E-Da HospitalI-Shou UniversityKaohsiung824TaiwanChina College of Medicine I-Shou UniversityKaohsiung840Taiwan Department of Medical Research E-Da HospitalI-Shou UniversityKaohsiung840TaiwanChina Sunw.y Business Sch.ol Sunway UniversitySelangor47500Malaysia International Gaming Research.Unit Psychology DepartmentNottingham Trent UniversityNottinghamNG14BUUK Department of Public h.alth College of MedicineNational Cheng Kung UniversityTainan701TaiwanChina Biostatistics Consulting Center National Cheng Kung University HospitalCollege of MedicineNational Cheng Kung UniversityTainan704TaiwanChina Department of Occupational Th.rapy College of MedicineNational Cheng Kung UniversityTainan701TaiwanChina

Background:Ph.sical inactivity is a major public h.alth.problem w.rldw.de th.t results in ph.sical and mental h.alth.*** major issue for ph.sical inactivity is w.igh. stigma(w.),especially perceived w.,w.ich.could lead to a tendency to avoid ph.sical activity(PA).To better understand th. association betw.en perceived w. and PA,know.edge of th. likely mediators in th.s association such.as w.igh. bias internalization(w.I)and psych.logical distress w.re investigated in th. present ***:Using a tw.-w.ve longitudinal study and convenient sampling,388 Taiw.n residents participants(55%females;mean age=29.7 years[SD±6.3])completed tw. surveys six month. *** mass index(BMI),Perceived w.igh. Stigma Scale(Pw.S),w.igh. Bias Internalization Scale(w.IS),Depression,Anxiety,Stress Scale(DASS-21),and Tendency to Avoid Ph.sical Activity and Sport Scale(TAPAS)w.re ***:A mediation model controlling for age,gender,and BMI w.th.5000 bootstrapping resamples w.s *** w. exerted significant direct effects on w.I(β=0.25;ph.logical distress(β=0.15;p=0.003),and tendency to avoid PA(β=0.10;p=0.027);w.I exerted a significant direct effect on tendency to avoid PA(β=0.47;pw.I and psych.logical distress on th. association betw.en perceived w. and tendency to avoid PA w.re 0.12 and 0.01,***:Given th. direct association of perceived w. on th. tendency to avoid PA and th. mediating role of w.I in th.s association,interventions addressing perceived w. and w.I may contribute to promoting ***,h.alth.interventionists(both.w.en planning and executing PA programs)need to consider w.igh. stigmaw.en encouraging ph.sical activity.

关键词： Mediation model ph.sical activity psych.logical distress w.igh. stigma young adults

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求职面试秘决

空中英语教室（初级版．大家说英语） 2024年第3期 44-45,56页

作者： Linda M.chung 不详

雇主们在招聘面试上经常会提出一些相同的要求。一个常见的要求是:“请向我介绍你自己。”你可以说一说自己成长的地方以及你的学历,也可以分享一些你的个人兴趣,例如你最喜欢的事。雇主可能会问:“你为什么想要应征这份工作?”你的答... 详细信息

雇主们在招聘面试上经常会提出一些相同的要求。一个常见的要求是:“请向我介绍你自己。”你可以说一说自己成长的地方以及你的学历,也可以分享一些你的个人兴趣,例如你最喜欢的事。雇主可能会问:“你为什么想要应征这份工作?”你的答案可以展现出你对这份工作以及这家公司的了解。在面试之前,先了解这家公司以及其提供的产品与各项服务。说出你为什么适合这份工作,还有你最喜欢这份工作以及这家公司的什么地方。

关键词：求职面试招聘面试个人兴趣雇主公司

QUENCh. IN STABILIZATION OF Cu-Zn-Al ALLOY

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中国有色金属学会会刊：英文版 1997年第3期7卷 100-103页

作者： Peng, Kun Tan, Sh.song Li, Sh.tang chung, C.Y. Lan, C.w.h. Central South.Univ of Tech.ology Changsha China

ＱＵＥＮＣＨＩＮＳＴＡＢＩＬＩＺＡＴＩＯＮＯＦＣｕＺｎＡｌＡＬＬＯＹ①ＰｅｎｇＫｕｎ，ＴａｎＳｈｕｓｏｎｇ，ＬｉＳｈｕｔａｎｇＤｅｐａｒｔｍｅｎｔｏｆＭａｔｅｒｉａｌｓＳｃｉｅｎｃｅａｎｄＥｎｇｉｎｅｒｉｎｇ，Ｃ... 详细信息

ＱＵＥＮＣＨＩＮＳＴＡＢＩＬＩＺＡＴＩＯＮＯＦＣｕＺｎＡｌＡＬＬＯＹ①ＰｅｎｇＫｕｎ，ＴａｎＳｈｕｓｏｎｇ，ＬｉＳｈｕｔａｎｇＤｅｐａｒｔｍｅｎｔｏｆＭａｔｅｒｉａｌｓＳｃｉｅｎｃｅａｎｄＥｎｇｉｎｅｒｉｎｇ，ＣｅｎｔｒａｌＳｏｕｔｈＵｎｉｖｅｒ...

关键词： sh.pe memory alloy stabilization quench.nt