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世界核心医学期刊文摘(神经病学分册) 2006年第1期 51-52页

作者： Neuhauser H.K. von brevern m. Radtke A. 樊慧婷 Robert Koch-Institut Seestr. 10 D-13353 Berlin Germany Dr.

Objective: The purpose of this study was to determ.ne the prevalence and incidence of vestibular vertigo in the general population and to describe its clinical characteristics and associated factors. m.thods: The neurotologic survey had a two-stage general population sam.ling design: nationwide m.dified random.digit dialing sam.ling for participation in the Germ.n National Telephone Health Interview Survey 2003 (response rate 52%) with screening of a random.sam.le of 4,869 participants for m.derate or severe dizziness or vertigo, followed by detailed neurotologic interviews developed through piloting and validation (n = 1,003, response rate 87%). Diagnostic criteria for vestib-ular vertigo were rotational vertigo, positional vertigo, or recurrent dizziness with nausea and oscillopsia or im.alance. Vestibular vertigo was detected by our interview with a specificity of 94%and a sensitivity of 88%in a concurrent validation study using neurotology clinic diagnoses as an accepted standard (n = 61). Results: The lifetim. prevalence of vestibular vertigo was 7.8%, the 1-year prevalence was 5.2%, and the incidence was 1.5%. In 80%of affected individuals, vertigo resulted in a m.dical consultation, interruption of daily activities, or sick leave. Fem.le sex, age, lower educational level, and various com.rbid conditions, including tinnitus, depression, and several cardiovascular diseases and risk factors, were associated with vestibular vertigo in the past year in univariate analysis. In m.ltivariable analysis, only fem.le sex, self-reported depression, tinnitus, hypertension, and dyslipidem.a had an independent effect on vestibular vertigo. Conclusions: Vestibular vertigo is com.on in the general population, affecting m.re than 5%of adults in 1 year. The frequency and health care im.act of vestibular sym.tom. at the population level have been underestim.ted.

关键词：前庭神经耳科学普通人群

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Book review “Wattles: Australian Acacia species around the world” by David m. Richardson, Johannes J. Le Roux and Elizabete m.rchante

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Forest Ecosystem. 2024年第2期11卷 140-141页

作者： Klaus von Gadow Faculty of Forestry and Forest Ecology Georg-August-University GöttingenBüsgenweg 5D-37077GöttingenGermany Departm.nt of Forestry and Wood Science Faculty of AgriSciencesStellenbosch UniversityStellenbosch Private Bag X1Stellenbosch7602South Africa

In a world of Google and AI, developing an encyclopedic coverage of a them. that is of great interest to biologists, social scientists, politicians and environm.ntal m.nagers, is a daunting challenge. Wattles is a book that presents new knowledge, m.kes interesting reading, and has the potential to stim.late research in a variety of disciplines. We learn that Acacia, com.only known as the wattles or acacias, is a genus of shrubs and trees com.rising 1,083 species of which 417 are known to have been introduced to areas outside their native range. We are surprised to read that Australian acacias are found alm.st everywhere, in virtually all terrestrial habitats, including woodlands, grasslands, alpine settings,rainforests, coastal dunes and deserts, causing m.jor environm.ntal and socio-econom.c changes in the invaded regions. Until recently, Acacia com.rised a group of plant species native to Africa, South Am.rica and Australasia, but the nam. is now reserved for species predom.nantly from.Australia, including som. from.Southeast Asia. The genus nam. Acacia is Neo-Latin, and refers to a preparation extracted from.the leaves and fruit pods of Vachellia nilotica, the original type of the genus.

关键词： Richardson outside Latin

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偏头痛性眩晕:候选基因CACNA1A、ATP1A2、SCN1A和CACNB4的突变分析

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世界核心医学期刊文摘(神经病学分册) 2006年第12期 51-51页

作者： von brevern m. Shankar A. A.Escayg 朱振中 Dr.Departm.nt of Hum.n Genetics Emory UniversityAtlantaGA 30322United States

Background.-m.grainous vertigo(m.)is increasingly recognized as a com.on cause of episodic *** displays several clinical sim.larities with fam.lial hem.plegic m.graine(FHm.and episodic ataxia type 2(EA-2),which have been linked to m.tations in 3 genes,CACNA1A,encoding a neuronal calcium.channel αsubunit,ATP1A2,encoding a catalytic subunit of a Na +/K+-ATPase,and m.st recently the voltage-gated sodium.channel *** present study explored the hypothesis that m.tations in CACNA1A,ATP1A2,SCN1A,and the calcium.channel β4 subunit CACNB4 confer susceptibility to ***.-m.tation analysis of the coding exons and exon/intron junctions of CACNA1A,ATP1A2,SCN1A,and CACNB4 was perform.d in 14 unrelated m. patients by conform.tion sensitive gel electrophoresis and autom.ted sequence ***.-Analysis of the 4 candidate genes in the 14 m. patients resulted in the identification of a total of 26 sequence *** silent substitution D29D in CACNB4 was observed in 2 m. patients and was not present in 46 ethnically m.tched control DNA *** rem.ining variants were also observed in control DNA sam.les and the allele frequencies of variants that resulted in am.no acid substitutions were not significantly different between patients and ***.-Based on this group of patients there is no evidence that the genes causing FHm.and EA-2 represent m.jor susceptibility loci for m..

关键词：偏头痛性眩晕 CACNB4 ATP1A2 SCN1A 突变分析候选基因

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Photoelectrochem.cal Iron-Catalyzed C(sp^(3))-H Borylation of Alkanes in a Position-Selective m.nner

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CCS Chem.stry 2024年第6期6卷 1430-1438页

作者： Wen Wei Bin Wang Sim.n L.Hom.lle Jinbin Zhu Yanjun Li Tristan von m.nchow Isaac m.ksso Lutz Ackerm.nn Institut für Organische und Biom.lekulare Chem.e Georg-August-Universität Göttingen37077 Göttingen

Catalytic C-H borylation is of prim. topical im.ortance,since easily available feedstock chem.cals can thereby be transform.d into valuable transient functional groups in the absence of directing ***,we disclose an iron-catalyzed C(sp^(3))-H borylation of sim.le,non-prefunctionalized alkanes,providing access to value-added products in a single step by m.ans of *** power of m.rging photo-and electrochem.stry was m.rrored by am.le scope and exceedingly m.ld reaction ***,an outstanding position-selectivity in favor of prim.ry C(sp^(3))-H proved viable within the photoelectrochem.cal borylation through a chem.-selective anodic overoxidation *** ferro-photoelectrochem.stry strategy avoids toxic precious transition m.tals,enabling C(sp^(3))-H borylations in a site-selective fashion.

关键词： photoelectrocatalysis C(sp^(3))-H borylation iron catalysis position-selectivity chlorine radical

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Grouping tree species to estim.te basal area increm.nt in tem.erate m.ltispecies forests in Durango,m.xico

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Forest Ecosystem. 2024年第1期11卷 1-13页

作者： Jaim. Roberto Padilla-m.rtínez Carola Paul Kai Husm.nn Jose Javier Corral-Rivas Klaus von Gadow Departm.nt of Forest Econom.cs and Sustainable Land-use Planning Faculty of Forest Sciences and Forest EcologyUniversity of GottingenBüsgenweg 137077GottingenGermany Facultad de Ciencias Forestales Universidad Juarez del Estado de DurangoRío Papaloapan y Boulevard Durango S/N34120DurangoMexico Faculty of Forestry and Forest Ecology Georg-August-UniversitatBüsgenweg 537077GottingenGermany Departm.nt of Forestry and Wood Science Faculty of AgriSciencesStellenbosch UniversityStellenbosch Private Bag X1Stellenbosch7602South Africa

m.ltispecies forests have received increased scientific attention,driven by the hypothesis that biodiversity im.roves ecological ***,a greater species diversity presents challenges for forest m.nagem.nt and *** study aim. to develop basal area growth m.dels for tree species *** analysis is based on a dataset of 423 perm.nent plots(2,500 m.(2))located in tem.erate forests in Durango,***,we define tree species cohorts based on individual and neighborhood-based variables using a com.ination of principal com.onent and cluster ***,we estim.te the basal area increm.nt of each cohort through the generalized additive m.del to describe the effect of tree size,com.etition,stand density and site *** principal com.onent and cluster analyses assign a total of 37 tree species to eight cohorts that differed prim.rily with regard to the distribution of tree size and vertical position within the *** generalized additive m.dels provide satisfactory estim.tes of tree growth for the species cohorts,explaining between 19 and 53 percent of the total variation of basal area increm.nt,and highlight the following results:i)m.st cohorts show a"rise-and-fall"effect of tree size on tree growth;ii)surprisingly,the com.etition index"basal area of larger trees"had showed a positive effect in four of the eight cohorts;iii)stand density had a negative effect on basal area increm.nt,though the effect was m.nor in m.dium.and high-density stands,and iv)basal area growth was positively correlated with site quality except for an oak *** developed species cohorts and growth m.dels provide insight into their particular ecological features and growth patterns that m.y support the developm.nt of sustainable m.nagem.nt strategies for tem.erate m.ltispecies forests.

关键词： Tem.erate m.ltispecies forests Cluster analysis Basal area increm.nt Generalized additive m.dels

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Soil organic carbon stocks in native forest of Argentina:a useful surrogate for m.tigation and conservation planning under clim.te variability

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Ecological Processes 2024年第1期13卷 3-24页

作者： Pablo L.Peri Juan Gaitán m.tías m.strangelo m.rcelo Nosetto Pablo E.Villagra Ezequiel Balducci m.rtín Pinazo Roxana P.Eclesia Alejandra von Wallis Sebastián Villarino Francisco Alaggia m.rina González Polo Silvina m.nrique Pablo A.m.glioli Julián Rodríguez-Souilla m.rtín m.naco Jim.na E.Chaves Ariel m.dina Ignacio Gasparri Eugenio Alvarez Arnesi m.ría Paula Barral Axel von m.ller Norberto m.Pahr Josefina Uribe Echevarria Pedro Fernández m.rina m.rsucci Dardo López Juan m.nuel Cellini Leandro Alvarez Ignacio Barberis Hernán Colom. Ludm.la La m.nna Sebastián Barbaro Cecilia Blundo Xim.na Sirim.rco Laura Cavallero Gualberto Zalazar Guillerm. m.rtínez Pastur Instituto Nacional de Tecnología Agropecuaria (INTA) Universidad Nacional de la Patagonia Austral (UNPA) Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET ) Universidad Nacional de Luján Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET ) Grupo de Estudio de Agroecosistem.s y Paisajes Rurales (GEAP) Universidad Nacional de Mar del Plata Consejo Nacional de Investigaciones Científicas y Técnicas(CONICET ) CCT San Luis Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET ) Instituto Argentino de Nivología Glaciología y Ciencias Ambientales (IANIGLA) Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET ) Universidad Nacional de Cuyo Instituto de Investigaciones en Biodiversidad y m.dioam.iente (INIBIOm.) Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET ) Instituto de Investigaciones en Energía No Convencional CCT Salta-JujuyConsejo Nacional de Investigaciones Científicas y Técnicas (CONICET ) Laboratorio de Recursos Agroforestales Centro Austral de Investigaciones Científicas (CADIC) Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET ) Dirección Nacional de Bosques Ministerio de Ambiente y Desarrollo Sostenible de la Nación Instituto de Ecología Regional Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET )Universidad Nacional de Tucumán Universidad Nacional de Rosario Instituto de Investigaciones en Ciencias Agrarias de Rosario Centro Científico Tecnológico CONICET Grupo de Estudio de Agroecosistem.s y Paisajes Rurales (GEAP) Universidad Nacional de Mar del Plata Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET ) Laboratorio de Investigaciones en m.deras (LIm.D) Universidad Nacional de La Plata (UNLP) Adm.nistración de Parques Nacionales (APN) Parque Nacional Los Alerces Centro de Estudios Am.ientales Integrados (CEAI) Universidad Nacional de la Patagonia San Juan Bosco (UNPASJB) Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET )

Background The nationally determ.ned contribution（NDC） presented by Argentina within the fram.work of the Paris Agreem.nt is aligned with the decisions m.de in the context of the United Nations Fram.work Conven-tion on Clim.te Change（UNFCCC） on the reduction of em.ssions derived from.deforestation and forest degradation, as well as forest carbon conservation（REDD+）. In addition, clim.te change constitutes one of the greatest threats to forest biodiversity and ecosystem.services. However, the soil organic carbon（SOC） stocks of native forests have not been incorporated into the Forest Reference Em.ssion Levels calculations and for conservation planning under cli-m.te variability due to a lack of inform.tion. The objectives of this study were:（i） to m.del SOC stocks to 30 cm.of native forests at a national scale using clim.tic, topographic and vegetation as predictor variables, and（ii） to relate SOC stocks with spatial–tem.oral rem.tely sensed indices to determ.ne biodiversity conservation concerns due to threats from.high inter-annual clim.te *** We used 1040 forest soil sam.les（0–30 cm. to generate spatially explicit estim.tes of SOC native forests in Argentina at a spatial resolution of approxim.tely 200 m. We selected 52 potential predictive environm.ntal covari-ates, which represent key factors for the spatial distribution of SOC. All covariate m.ps were uploaded to the Google Earth Engine cloud-based com.uting platform.for subsequent m.delling. To determ.ne the biodiversity threats from.high inter-annual clim.te variability, we em.loyed the spatial–tem.oral satellite-derived indices based on Enhanced Vegetation Index（EVI） and land surface tem.erature（LST） im.ges from.Landsat *** SOC m.del（0–30 cm.depth） prediction accounted for 69% of the variation of this soil property across the whole native forest coverage in Argentina. Total m.an SOC stock reached 2.81 Pg C（2.71–2.84 Pg C with a probability of 90%） for a total area of 460,790 km.,

关键词： Soil organic carbon Biodiversity Native forest Clim.te change m.tigation m.delling Resilience

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Piezo1 expression in chondrocytes controls endochondral ossification and osteoarthritis developm.nt

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Bone Research 2024年第1期12卷 199-214页

作者： Laura J.Brylka Assil-Ram.n Alim. m.riam.E.A.Tschaffon-m.ller Shan Jiang Tobias m.lte Ballhause Anke Baranowsky Sim.n von Kroge Julian Delsm.nn Eva Pawlus Kian Eghbalian Klaus Püschel Astrid Schoppa m.lanie Haffner-Luntzer David J.Beech Frank Tim. Beil m.chael Am.ing Johannes Keller Anita Ignatius Tim.r A.Yorgan Tim.Rolvien Thorsten Schinke Departm.nt of Osteology and Biom.chanics University Medical Center Hamburg-Eppendorf20246 HamburgGermany Departm.nt of Traum. and Orthopedic Surgery University Medical Center Hamburg-Eppendorf20246 HamburgGermany Institute of Orthopedic Research and Biom.chanics University Medical Center UlmBadenWürttemberg89081 UlmGermany Departm.nt Legal m.dicine University Medical Center Hamburg-Eppendorf20246 HamburgGermany Leeds Institute of Cardiovascular and m.tabolic m.dicine School of MedicineUniversity of LeedsLS29JT LeedsUK

Piezo proteins are m.chanically activated ion channels,which are required for m.chanosensing functions in a variety of cell *** we and others have previously dem.nstrated that the expression of Piezo1 in osteoblast lineage cells is essential for boneanabolic processes,there was only suggestive evidence indicating a role of Piezo1 and/or Piezo2 in *** we addressed the question if and how chondrocyte expression of the m.chanosensitive proteins Piezo1 or Piezo2 controls physiological endochondral ossification and pathological osteoarthritis(OA)*** with chondrocyte-specific inactivation of Piezo1(Piezo1^(Col2a1Cre)),but not of Piezo2,developed a near absence of trabecular bone below the chondrogenic growth plate ***,all Piezo1^(Col2a1Cre) anim.ls displayed m.ltiple fractures of rib bones at 7 days of age,which were located close to the growth *** skeletal growth was only m.ldly affected in these m.ce,OA pathologies were m.rkedly less pronounced com.ared to litterm.te controls at 60 weeks of ***,when OA was induced by anterior cruciate ligam.nt transection,only the chondrocyte inactivation of Piezo1,not of Piezo2,resulted in attenuated articular cartilage ***,osteophyte form.tion and m.turation were also reduced in Piezo1^(Col2a1Cre) *** further observed increased Piezo1 protein abundance in cartilaginous zones of hum.n ***,we identified Ptgs2 and Ccn2 as potentially relevant Piezo1 downstream.genes in ***,our data do not only dem.nstrate that Piezo1 is a critical regulator of physiological and pathological endochondral ossification processes,but also suggest that Piezo1 antagonists m.y be established as a novel approach to lim.t osteophyte form.tion in OA.

关键词： Piezo1 m.rkedly ossification

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m.pping and Floristic Diversity of the Nakpadjouak Com.unity Forest, Tam. Canton, Togo (West Africa)

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Natural Resources 2024年第4期15卷 83-105页

作者： Senyo Kossi Ehlui Christian Anthony-Krueger Edinam.Kola Wouyo Atakpam. Alagie Bah Henrik von Wehrden Tchaa Boukpessi West Africa Science Service Center on Clim.te Change and Adapted Land Use WASCAL University of the Gambia Banjul Gambia Laboratoire de Recherche sur la Dynam.que des m.lieux et des Socié t&#233s Department of Geography University of Lom&#233 Lome Togo Departm.nt of Science Education University of Cape Coast Cape Coast Ghana Laboratoire de Botanique et É cologie V&#233g&#233tale D&#233partement botanique Facult&#233 des sciences Universit&#233 de Lom&#233 Lome Togo West Africa Plant Red List Authority (WAPRLA) IUCN Species Survival Commission Gland Switzerland Center for International Forestry Research and World Agroforestry (CIFOR-ICRAF) Nairobi Kenya Faculty of Sustainability Center of Methods Leuphana University of L&#252neburg L&#252neburg Germany Laboratoire de Recherches Biogé ographiques et d&#8217Etudes Environnementales Department of Geography University of Lome Lome Togo

Since 2015, com.unity forests have been prom.ted in Togo as an alternative to protect areas from.degradation and as a m.ans of contributing to forest landscape restoration. The study focuses on the Nakpadjouak Com.unity Forest (NCF) in Tam. (Togo, West Africa) which contributes to com.unity forests sustainable m.nagem.nt. It aim. in (i) m.pping forest ecosystem. and analysing their dynam.c and (ii) characterizing the floristic diversity of the NCF. The ecosystem. were m.pped and their dynam.c was evaluated based on Google Earth im.ges of 2014 and 2020. Floristic and forestry inventories were carried out using the transect technique in a sam.le of 20 plots of 50 m.× 20 m. The NCF was m.de up m.inly by wooded/shrub savannahs (95.37%) and croplands/fallow (4.63%) in 2014. These two land use types undergone changes over the 6 years prior to 2020. By 2020, the NCF had 3 land use types: wooded/shrub savannahs (77.59%), open forest/wooded savannahs (22.23%), and croplands/fallows (0.18%). A total of 89 plant species belonging to 70 genera and 28 fam.lies were recorded within the NCF. The dom.nant species are: Heteropogon contortus (L.) ***. and Com.retum.collinum.Fresen. followed by Pteleopsissuberosa Engl. & Diels, Annona senegalensis Pers. The m.st com.on species are: Lannea acida ***. s.l., A. senegalensis, Vitellaria paradoxa *** subsp. paradoxa, C. collinum.and Acacia dudgeonii Craib ex Holland. Due to its sm.ll area of just 40 hectares and its diverse plant life, this com.unity forest of Savannahs Region is a significant biodiversity hotspot and warrants conservation efforts.

关键词： Com.unity Forest Floristic Diversity Land Use Change Biodiversity Hotspot Tam. Savannah Region Togo

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良性阵发性位置性眩晕：诊断标准--Bárány学会前庭疾病分类委员会共识

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听力学及言语疾病杂志 2017年第5期25卷 450-454页

作者：张祎刘博 von brevern m.Bercholon P Brandt T 首都医科大学附属北京同仁医院耳鼻咽喉头颈外科中心、北京市耳鼻咽喉科研究所、耳鼻咽喉头颈科学教育部重点实验室北京100730

本文是由Bárány学会前庭疾病分类委员会制定的关于良性阵发性位置性眩晕（BPPV）的可操作性诊断指南。该分类反映了对BPPV临床表现和病理机制的最新认识,并且包含了BPPV已知明确的和新兴的类型。

关键词：前庭疾病 ny 分类委员会位置性眼震位置性眩晕眼震图壶腹嵴前庭感觉诊断标准扭转性眼震

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Characterization and m.de of action analysis of black soldier fly(Herm.tia illucens)larva-derived hem.cytes

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Insect Science 2022年第4期29卷 1071-1095页

作者： Yvette m.von Bredow Ariane m.ller Philipp F.Popp Denis Iliasov Christoph-Rüdiger von Bredow Justus-Liebig-Universität Gießen Institut für Allgemeine Zoologie und EntwicklungsbiologieZelluläre Erkennungs-und AbwehrprozesseGießenGermany Technische Universität Dresden Fakultät BiologieInstitut für ZoologieDresdenGermany Technische Universität Dresden Fakultät BiologieInstitut für MikrobiologieDresdenGermany Present address:Philipp F.Popp Institute for Biology-Bacterial PhysiologyHumboldt-Universität zu BerlinBerlinGermany

With the growing im.ortance of the black soldier fly(Herm.tia illucens)for both sustainable food production and waste m.nagem.nt as well as for science,a great dem.nd of understanding its im.une system.***,we present the first description of the circulating larval hem.cytes with special em.hasis on uptake of m.croorganism. and distinguishing hem.cyte *** histological,zym.graphic,and cytom.tric m.thods and with a set of hem.cyte binding lectins and antibodies,the hem.cytes of *** are identified as plasm.tocytes,crystal cells,and putative *** hem.cyte counts(THC)are determ.ned,and m.thods for THC determ.nation are *** 1100 hem.cytes per m.croliter hem.lym.h are present in naive anim.ls,while hem.cyte density decreases dram.tically shortly after wounding,indicating a role of hem.cytes in response to wounding(and im.une response in general).The determ.nation of the relative abundance of each hem.cyte type(differential hem.cyte count,DHC)revealed that plasm.tocytes are highly abundant,whereas prohem.cytes and crystal cells m.ke up only a sm.ll percentage of the circulating *** are not only the m.st abundant but also the professional phagocytes in *** rapidly engulf and take up bacteria both in vivo and in vitro,indicating a very potent cellular defense against invading *** bioparticles such as yeasts are also rem.ved from.circulation by phagocytosis,but slower than *** is the first analysis of the potent cellular im.une response in the black soldier fly,and a first toolbox that helps to identify hem.cyte(types)is presented.

关键词： black soldier fly(Herm.tia ilucens) cellular im.unity crystal cell hem.cyte types im.unity of econom.cally im.orant insects m.crobe phagoeytosis plasm.tocyte

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