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Delirium,insulin-like growth factor I,growth hormone in older inpatients

World Journal of Psychiatry 2020年第9期10卷 212-222页

作者： Dimitrios Adamis Iulian Coada Piet Eikelenboom Che-Sheng Chu Karen Finn vincent melvin John Williams David James Meagher Geraldine McCarthy Department of Psychiatry Sligo/Leitrim Mental Health ServicesSligo F91 CD34Ireland Department of Psychiatry Research and Academic Institute of AthensAthens 11742Greece Department of Psychiatry University Hospital LimerickLimerick V94 F858Ireland Department of Psychiatry GGZinGeest and VuMCAmsterdam 1081 HVthe Netherlands Department of Psychiatry and Center for Geriatric and Gerontology Kaohsiung Veterans General HospitalKaohsiung 81362Taiwan Department of Biopharmaceutical and Medical Science School of Science and ComputingGalway-Mayo Institute of TechnologyGalway H91 T8NWIreland Department of Pathology Sligo University HospitalSligo F91 H684Ireland

BACKGROUND Delirium is a common disorder in elderly medical inpatients with serious adverse outcomes and is characterized by sudden onset,disturbance in attention,awareness,consciousness and cognition,and often with behavioural *** to understanding delirium,is understanding mechanisms by which body and brain wellbeing are linked and in particular how brain responses to bodily homeostatic stress is mediated.A number of studies have investigated the relationship between insulin-like growth factor I(IGF-I)and delirium in medically ill hospitalised patients with conflicting ***,none have investigated growth hormone(GH)which is related to IGF-I via negative *** To investigate the relationship between serum levels of IGF-I and GH,and the occurrence of *** Prospective,longitudinal,observational *** elderly inpatients(aged 70+),were assessed twice weekly with Montreal cognitive assessment(MoCA),Confusion assessment method(CAM),Acute Physiology and Chronic Health Evaluation *** was defined using *** history of dementia was evaluated with the Informant Questionnaire on Cognitive Decline in the ***-I and GH levels were estimated with the ELISA *** estimating equations(GEE)model was applied for the first five assessments to analyze those longitudinal *** The sample consisted of 198 participants(mean age 80.63±6.81;range 70-97).Of these 92(46.5%)were *** six(43.4%)were identified with a history of *** or prevalent delirium during hospitalisation was identified with CAM in 40 participants(20.2%).Evaluation of missing values with Little's MCAR test indicated that they were missing completely at random(MCARχ2=12.24,u:9,P=0.20).Using GEE for the analysis we found that low MoCA scores,low levels of IGF-I and high levels of GH were significantly associated with any delirium(prevalence,incident,or fluctuating,during the study period(Waldχ2=12.231;u:

关键词： Delirium Pathophysiology Insulin-like growth factor-I Growth hormone Older people Physical illness Cognition Old age psychiatry

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Nonlinear Characteristic Analysis of Gas-Interconnected Quasi-Zero Stiffness Pneumatic Suspension System:A Theoretical and Experimental Study

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Chinese Journal of Mechanical Engineering 2024年第3期37卷 338-352页

作者： Xinwei Jiang Xing Xu Tianling Shi vincent Akolbire Atindana Automotive Engineering Research Institute Jiangsu UniversityZhenjiang 212013China

Because of significantly changed load and complex and variable driving road conditions of commercial vehicles,pneumatic suspension with lower natural frequencies is widely used in commercial vehicle suspension *** ever,traditional pneumatic suspension system is hardly to respond the greatly changed load of commercial vehicles To address this issue,a new Gas-Interconnected Quasi-Zero Stiffness Pneumatic Suspension(GIQZSPS)is presented in this paper to improve the vibration isolation performance of commercial vehicle suspension systems under frequent load *** new structure adds negative stiffness air chambers on traditional pneumatic suspension to reduce the natural frequency of the *** can adapt to different loads and road conditions by adjusting the solenoid valves between the negative stiffness air ***,a nonlinear mechanical model including the dimensionless stiffness characteristic and interconnected pipeline model is derived for GIQZSPS *** the nonlinear mechanical model of GIQZSPS system,the force transmissibility rate is chosen as the evaluation index to analyze ***,a testing bench simulating 1/4 GIQZSPS system is designed,and the testing analysis of the model validation and isolating performance is carried *** results show that compared to traditional pneumatic suspension,the GIQZSPS designed in the article has a lower natural *** the system can achieve better vibration isolation performance under different load states by switching the solenoid valves between air chambers.

关键词： Pneumatic suspension Quasi-zero stiffness system Gas-interconnected system Nonlinear dynamic modeling

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Evolution of the rare earth trade network:A perspective of dependency and competition

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Geoscience Frontiers 2024年第3期15卷 183-191页

作者： Jilan Xu Jiahao Li vincent Charles Xin Zhao School of Urban and Regional Science Shanghai University of Finance and EconomicsShanghai 200433China School of Business East China University of Science and TechnologyShanghai 200237China School of Management University of BradfordBradford BD71DPUnited Kingdom School of Statistics and Applied Mathematics Anhui University of Finance and EconomicsBengbu 233030China

As a global strategic reserve resource,rare earth has been widely used in important industries,such as military equipment and ***,existing analyses based solely on the total volume of rare earth trade fail to uncover the underlying competition and dependency *** address this gap,this paper employs the principles of trade preference and import similarity to construct dependency and competition *** network analysis is then employed to study the evolution of the global rare earth trade network from 2002 to *** main conclusions are as *** global rare earth trade follows the Pareto principle,and the trade network shows a scale-free *** has emerged as the world’s largest importer and exporter of rare earth since *** the dependency network,China has become the most dependent country since *** result of community division shows that China has separated from the American community and formed new communities with the Association of Southeast Asian Nations(ASEAN)*** United States of America has formed a super-strong community with European and Asian *** the competition network,the distribution of competition intensity follows a scale-free *** countries face low-intensity competition,but there are numerous competing *** competition related to China has increased ***,the competition source for the United States of America has shifted from Mexico to China,resulting in China,the USA,and Japan becoming the core participants in the competition network.

关键词： Rare earth Trade network Dependency Competition Complex network analysis

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Reinforcement Learning-Empowered Graph Convolutional Network Framework for Data Integrity Attack Detection in Cyber-Physical Systems

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CSEE Journal of Power and Energy Systems 2024年第2期10卷 797-806页

作者： Edeh vincent Mehdi Korki Mehdi Seyedmahmoudian Alex Stojcevski Saad Mekhilef School of Science Computingand Engineering TechnologiesSwinburne University of TechnologyMelbourneAustralia

The massive integration of communication and information technology with the large-scale power grid has enhanced the efficiency, safety, and economical operation of cyber-physical systems. However, the open and diversified communication environment of the smart grid is exposed to cyber-attacks. Data integrity attacks that can bypass conventional security techniques have been considered critical threats to the operation of the grid. Current detection techniques cannot learn the dynamic and heterogeneous characteristics of the smart grid and are unable to deal with non-euclidean data types. To address the issue, we propose a novel Deep-Q-Network scheme empowered with a graph convolutional network (GCN) framework to detect data integrity attacks in cyber-physical systems. The simulation results show that the proposed framework is scalable and achieves higher detection accuracy, unlike other benchmark techniques.

关键词： Deep reinforcement learning graph convolutional network heterogeneous smart grid network

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Anonymity preserving lightweight authentication protocol for resource-limited wireless sensor networks

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High-Confidence Computing 2024年第2期4卷 82-95页

作者： vincent Omollo Nyangaresi Ganesh Keshaorao Yenurkar Jaramogi Oginga Odinga University of Science&Technology BondoKenya Yeshwantrao Chavan College of Engineering Wanadongri 441110India

Wireless sensor networks have been deployed in areas such as healthcare,military,transportation and home automation to collect data and forward it to remote users for further *** open wireless communication channels are utilized for data transmissions,the exchanged messages are vulnerable to various threats such as eavesdropping and message ***,many security solutions have been introduced to address these ***,the resource-constrained nature of the sensor nodes makes it inefficient to deploy the conventional security schemes which require long keys for improved ***,lightweight authentication protocols have been ***,majority of these schemes are still insecure while others incur relatively higher energy,computation,communication and storage *** this paper,a protocol that deploys only lightweight one-way hashing and exclusive OR operations is *** formal security analysis using Real-or Random(ROR)model demonstrates its capability to uphold the security of the derived session *** addition,its semantic security evaluation shows that it offers user privacy,anonymity,untraceability,authentication,session key agreement and key ***,it is shown to resist attacks such as side-channeling,physical capture,eavesdropping,offline guessing,spoofing,password loss,session key disclosure,forgery and *** terms of performance,it has relatively lower communication overheads and improves the computation costs and supported security characteristics by 31.56%and 33.33%respectively.

关键词： Anonymity Authentication Formal security Lightweight Privacy Sensor WSN

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Next generation multiple access for IMT towards 2030 and beyond

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Science China(Information Sciences) 2024年第6期67卷 448-450页

作者： Zhiguo DING Robert SCHOBER Pingzhi FAN H.vincent POOR Department of Computer and Information Engineering Khalifa University Department of Electrical and Electronic Engineering University of Manchester Institute for Digital Communications Friedrich Alexander-University Erlangen-Nurnberg (FAU) CSNMT International Cooperation Research Center (MoST) Southwest Jiaotong University Department of Electrical and Computer Engineering Princeton University

Multiple access techniques are fundamental to the design of wireless communication systems,since many crucial components of such systems depend on the choice of the multiple access technique[1].For example,the use of ...

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Fluidization and Transport of Vibrated Granular Matter:A Review of Landmark and Recent Contributions

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Fluid Dynamics & Materials Processing 2024年第1期20卷 1-29页

作者： Peter Watson Sebastien vincent Bonnieu Marcello Lappa Department of Mechanical and Aerospace Engineering University of StrathclydeGlasgowUK European Space Agency European Space Research and Technology CentreNoordwijkNetherland

We present a short retrospective review of the existing literature about the dynamics of(dry)granular matter under the effect of *** main objective is the development of an integrated resource where vital information about past findings and recent discoveries is provided in a single *** attention is paid to those works where successful synthetic routes to as-yet unknown phenomena were *** landmark results are analyzed,while smoothly blending them with a history of the field and introducing possible categorizations of the prevalent *** no classification is perfect,and it is hard to distillate general properties out of specific observations or realizations,two possible ways to interpret the existing results are defined according to the type of forcing or the emerging(ensuing)regime of *** particular,first results concerning the case where vibrations and gravity are concurrent(vertical shaking)are examined,then the companion situation with vibrations perpendicular to gravity(horizontal shaking)is *** classes are introduced as follows:(1)Regimes where sand self-organizes leading to highly regular geometrical“pulsating”patterns(thin layer case);(2)Regimes where the material undergoes“fluidization”and develops an internal multicellular convective state(tick layers case);(3)Regimes where the free interface separating the sand from the overlying gas changes inclination or develops a kind a patterned configuration consisting of stable valleys and mountains or travelling waves;(4)Regimes where segregation is produced,i.e.,particles of a given size tend to be separated from the other grains(deep containers).Where possible,an analogy or parallelism is drawn with respect to the companion field of fluid-dynamics for which the assumption of“continuum”can be applied.

关键词： Granular materials vibrations fluidization flowability symmetry breaking

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Assembly of peptide nanostructures with controllable sizes

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Nano Research 2024年第1期17卷 151-161页

作者： Dan Cheng Fan Jia Yun-Bao Jiang vincent P.Conticello Tao Jiang The MOE Key Laboratory of Spectrochemical Analysis and Instrumentation Department of ChemistryCollege of Chemistry and Chemical EngineeringXiamen UniversityXiamen 361005China Innovation Laboratory for Sciences and Technologies of Energy Materials of Fujian Province(IKKEM) Xiamen 361005China Department of Chemistry Emory UniversityAtlanta 30033USA

Controlled peptide assembly offers significant promise to develop synthetic supramolecular nanostructures to display material and biological properties that mimic protein assemblies in *** the progress in forming peptide nanostructures of various morphology,there exists a distinct gap between natural and synthetic assembly systems in terms of size *** nanostructures with a narrow size distribution that can be tuned over a wide range of length-scales is essential for applications that require precise spacing between *** approach provides the opportunity to correlate materials and biological properties of interest with assembly *** this review,we discuss representative endeavors over the past two decades for design of size-controllable peptide nanostructures using tunable building *** mechanisms for size control,e.g.,molecular frustration,template-directed peptide assembly,and multi-component peptide co-assembly,will also be *** also demonstrate the applicable scopes of these strategies and suggest potential future avenues for scientific advances in this field.

关键词： peptide assembly controllable size template multi-component

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The Artificial Disc Nucleus and Other Strategies for Replacement of the Nucleus Pulposus:Past,Present and Future Designs for an Emerging Surgical Solution

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Engineered Regeneration 2024年第2期5卷 269-281页

作者： Greg Sacks vincent DeStefano Claire Parker Ryan Lebens Harry Mushlin Renaissance School of Medicine at Stony Brook University Stony BrookNYUSA

Nucleus Pulposus(NP)Replacement is a developing surgical methodology for the treatment of pathology related to degeneration of intervertebral discs(IVDs).This article provides necessary context regarding the patholo-gies treated with this technology,the biomechanical structure and function of the IVD,and the procedures this technology aims to ***,it provides an overview and discussion of commercial and experimental preformed and in situ curing prosthesis designs reported in the scientific literature and summarizes the results of biomechanical and clinical studies evaluating their *** and updated information on the most recent research into NP replacement with novel hydrogel and tissue engineering(TE)strategies is *** of the NP allows for potential improvement in the treatment of degenerative spinal pathologies through minimally invasive surgical techniques.

关键词： Nucleus Pulposus Intradiscal Prosthesis Hydrogel Artificial Disc Implant Spine Surgery

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Systematic review of risk factors,prognosis,and management of colorectal signet-ring cell carcinoma

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World Journal of Gastrointestinal Oncology 2024年第5期16卷 2141-2158页

作者： Frederiek Nuytens vincent Drubay Clarisse Eveno Florence Renaud Guillaume Piessen Department of Digestive and Oncological Surgery University LilleClaude Huriez University HospitalLille 59000France Department of Digestive and Hepatobiliary/Pancreatic Surgery AZ GroeningeKortrijk 8500Belgium Cambrai Hospital Center and Sainte Marie Group of Hospitals of The Catholic Institute of LilleCambrai 59400France CNRS InsermUMR9020-U1277-CANTHER-CancerUniversity LilleCHU LilleLille 59000France

BACKGROUND Colorectal signet-ring cell carcinoma(CSRCC)is a rare clinical entity which accounts for approximately 1%of all colorectal *** multiple studies concerning this specific topic have been published in the past decades,the pathogenesis,associated risk factors,and potential implications on treatment are still poorly *** the low incidence,historically confusing histological criteria have resulted in confusing ***,the rising incidence of CSRCC along with relatively young age at presentation and associated dismal prognosis,highlight the actual interest to synthesize the known literature regarding *** To provide an updated overview of risk factors,prognosis,and management of *** A literature search in the MEDLINE/PubMed database was conducted with the following search terms used:‘Signet ring cell carcinoma’and‘colorectal’.Studies in English language,published after January 1980,were *** included in the qualitative synthesis were evaluated for content concerning epidemiology,risk factors,and clinical,diagnostic,histological,and molecular features,as well as metastatic pattern and therapeutic *** possible,presented data was extracted in order to present a more detailed overview of the *** In total,67 articles were included for qualitative analysis,of which 54 were eligible for detailed data *** has a reported incidence between 0.1%-2.4%and frequently presents with advanced disease stage at the time of *** is associated with an impaired overall survival(5-year OS:0%-46%)and a worse stagecorrected outcome compared to mucinous and not otherwise specified *** systematic use of exploratory laparoscopy to determine the presence of peritoneal metastases has been *** is the mainstay of treatment,although the rates of curative resection in CSRCC(21%-82%)are lower compared to those in other histological *** case of peritoneal

关键词： Colorectal cancer Signet-ring cell histology Poorly cohesive cells Systematic review Risk factors Prognosis Therapeutic management

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