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Advancing engineered approaches for sustainable wound regeneration and repair:Harnessing the potential of green synthesized silver nanoparticles

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Engineered Regeneration 2024年第3期5卷 306-325页

作者： J.Nandhini E.Karthikeyan E.Elizabeth Rani V.S.Karthikha D.Sakthi Sanjana H.Jeevitha S.Rajeshkumar vijayan venugopal A.Priyadharshan Department of Pharmaceutics Saveetha College of PharmacySaveetha Institute of Medical and Technical SciencesChennai 602105India Department of Pharmaceutical Chemistry Saveetha College of PharmacySaveetha Institute of Medical and Technical SciencesChennai 602105India Department of Pharmacology Saveetha Dental College and HospitalSaveetha Institute of Medical and Technical SciencesChennaiIndia Department of Pharmaceutics School of PharmacySri Balaji Vidyapeeth(Deemed to be university)PuducherryIndia Department of conservative Dentistry and Endodontics Saveetha Dental College and HospitalSaveetha Institute of Medical and Technical SciencesSaveetha UniversityChennaiIndia

Wound healing is a crucial biological process for tissue repair and regeneration,preventing infections and ***’s been a growing interest in exploring sustainable wound healing strategies in recent *** review examines the use of green-synthesized silver nanoparticles(AgNPs)in sustainable wound healing *** highlights the need for innovative approaches and the challenges posed by *** current wound therapies and treatments,highlighting gaps in existing methodologies,are *** review provides a com-prehensive overview of the current state-of-the-art in green synthesis techniques for the synthesis of *** properties and characterization of AgNPs are elucidated,providing insights into their *** biocompati-bility of AgNPs in wound healing is also explored,emphasizing safety in medical *** synthesized AgNPs incorporated wound dressings are detailed,showcasing their potential in clinical *** and future perspectives are discussed,addressing hurdles to widespread *** conclusion consolidates key findings,offering a synthesized perspective on the potential of green-synthesized AgNPs in revolutionizing current knowledge on innovative approaches for sustainable wound healing practices.

关键词： Green synthesis Wound healing AgNPs Wound healing mechanism Eco-friendly synthesis

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Multi-compartmental transdermal patch for simultaneous delivery of multiple drugs:formulation and evaluation of newly developed novel dosage form

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Journal of Coastal Life Medicine 2015年第7期 534-538页

作者： vijayan venugopal Jayaraja Kumar Selvadurai Muralidharan P.Vasanth Raj Unit of Pharmaceutical Technology Faculty of PharmacyAIMST UniversityBedong-08100Malaysia

Objective:To evaluate the formulation of multi-compartmental transdermal patches for simultaneous delivery of multiple drugs:aceclofenac and ***:The patch was prepared by simple solvent casting method using hydroxy propyl methyl celluloseK100Mas matrix forming agent and dimethyl sulphoxide as permeation *** prepared transdermal patch was evaluated by physiochemical parameters andin-vitro diffusion ***:The multi-compartmental transdermal patch showed sustained drug release over the period of 12 ***:Multicompartmental transdermal patches shows better bioavailability,therapeutic efficacy and very economic as compared with other dosage forms.

关键词： Multi-compartmental Transdermal patch Aceclofenac Serratiopeptidase

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A Machine Learning Approach for MRI Brain Tumor Classification

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Computers, Materials & Continua 2017年第2期53卷 91-108页

作者： Ravikumar Gurusamy vijayan Subramaniam Assistant Professor/ECE Vivekanandha Institute of Engineering and Technology for Women ElayampalamTiruchengodeNamakkal(Dt)-637205 Principal Surya Engineering CollegeMettukkadaiErode-638107.

A new method for the denoising,extraction and tumor detection on MRI images is presented in this *** images help physicians study and diagnose diseases or tumors present in the *** work is focused towards helping the radiologist and physician to have a second opinion on the *** ambiguity of Magnetic Resonance(MR)image features is solved in a simpler *** MRI image acquired from the machine is subjected to analysis in the *** real-time data is used for the *** preprocessing is performed using various filters for noise *** de-noised image is segmented,and the feature extractions are *** are extracted using the wavelet *** compared to other methods,the wavelet transform is more suitable for MRI image feature *** features are given to the classifier which uses binary tree support vectors for *** classification process is compared with conventional methods.

关键词： MRI image brain pathology K-Means algorithm Feature extraction Wavelet transform SVM Neural network K nearest algorithm.

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Parametric optimization of friction stir welding process of age hardenable aluminum alloys-ANFIS modeling

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Journal of Central South University 2016年第8期23卷 1847-1857页

作者： D.vijayan V.Seshagiri Rao Department of Mechanical Engineering Sri Chandrasekharendra Saraswathi Viswa Maha Vidyalaya Enathur Kanchipuram- 631561 Tamilnadu India St. Joseph's College of Engineering Chennai - 600025 Tamilnadu India

A comparative approach was performed between the response surface method(RSM) and the adaptive neuro-fuzzy inference system(ANFIS) to enhance the tensile properties, including the ultimate tensile strength and the tensile elongation, of friction stir welded age hardenable AA6061 and AA2024 aluminum alloys. The effects of the welding parameters, namely the tool rotational speed, welding speed, axial load and pin profile, on the ultimate tensile strength and the tensile elongation were analyzed using a three-level, four-factor Box-Behnken experimental design. The developed design was utilized to train the ANFIS models. The predictive capabilities of RSM and ANFIS were compared based on the root mean square error, the mean absolute error, and the correlation coefficient based on the obtained data set. The results demonstrate that the developed ANFIS models are more effective than the RSM model.

关键词： aluminum alloys response surface method(RSM) adaptive neuro-fuzzy inference system(ANFIS) friction stir welding Box-Behnken design neuro fuzzy

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Hidden Two-Stream Collaborative Learning Network for Action Recognition

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Computers, Materials & Continua 2020年第6期63卷 1545-1561页

作者： Shuren Zhou Le Chen vijayan Sugumaran School of Computer and Communication Engineering Changsha University of Science and TechnologyChangsha410114China Department of Decision and Information Sciences School of Business AdministrationOakland UniversityRochester48309USA

The two-stream convolutional neural network exhibits excellent performance in the video action *** crux of the matter is to use the frames already clipped by the videos and the optical flow images pre-extracted by the frames,to train a model each,and to finally integrate the outputs of the two ***,the reliance on the pre-extraction of the optical flow impedes the efficiency of action recognition,and the temporal and the spatial streams are just simply fused at the ends,with one stream failing and the other stream *** propose a novel hidden two-stream collaborative(HTSC)learning network that masks the steps of extracting the optical flow in the network and greatly speeds up the action *** on the two-stream method,the two-stream collaborative learning model captures the interaction of the temporal and spatial features to greatly enhance the accuracy of *** proposed method is highly capable of achieving the balance of efficiency and precision on large-scale video action recognition datasets.

关键词： Action recognition collaborative learning optical flow

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Tectonic significance of dykes in the Sarnu-Dandali alkaline complex,Rajasthan, northwestern Deccan Traps

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Geoscience Frontiers 2016年第5期7卷 783-791页

作者： Anjali vijayan Hetu Sheth Kamal Kant Sharma Department of Earth Sciences Indian Institute of Technology Bombay (IITB) Department of Geology Government Postgraduate College

Whether swarms of preferentially oriented dykes are controlled by regional stress fields, or passively exploit basement structural fabric, is a much debated question, with support for either scenario in individual case studies. The Sarnu-Dandali alkaline complex, near the northwestern limit of the Deccan Traps continental flood basalt province, contains mafic to felsic alkaline volcano-plutonic rocks and carbonatites. The complex is situated near the northern end of the 600 km long, NNWe SSE-trending Barmer-Cambay rift. Mafic enclave swarms in the syenites suggest synplutonic mafic dykes injected into a largely liquid felsic magma chamber. Later coherent dykes in the complex, of all compositions and sizes,dominantly strike NNWe SSE, parallel to the Barmer-Cambay rift. The rift formed during two distinct episodes of extension, NWe SE in the early Cretaceous and NEe SW in the late Cretaceous. Control of the southern Indian Dharwar structural fabric on the rift trend, as speculated previously, is untenable,whereas the regional Precambrian basement trends（Aravalli and Malani） run NEe SW and NNEe *** therefore suggest that the small-scale Sarnu-Dandali dykes and the much larger-scale BarmerCambay rift were not controlled by basement structure, but related to contemporaneous, late Cretaceous regional ENEe WSW extension, for which there is varied independent evidence.

关键词： Dyke swarms Alkaline magmatism Deccan Traps Sarnu-Dandali Barmer-Cambay rift

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Dual antidiabetic and antihypertensive activity of fucoxanthin isolated from Sargassum wightii Greville in in vivo rat model

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Food Science and Human Wellness 2023年第5期12卷 1693-1700页

作者： vijayan Raji Chitra Loganathan Thiyagarajan Ramesh Palvannan Thayumanavan Department of Biochemistry Periyar UniversitySalemTamil Nadu 636011India Department of Basic Medical Sciences College of MedicinePrince Sattam Bin Abdulaziz UniversityAl-Kharj 11942Kingdom of Saudi Arabia

In a previous study from our laboratory, fucoxanthin purified from brown algae, Sargassum wightii Greville has found to exhibit antioxidant activity and inhibition of angiotensin-I-converting enzyme(ACE)in vitro. The present study aims in understanding the protective effect of fucoxanthin purified from S. wightii against diabetes with hypertension in in vivo. Diabetes and hypertension were induced in rat by streptozotocin and sodium chloride treatment, respectively. In diabetes with hypertension rat, the blood pressure was increased along with hyperglycemia. Administration of fucoxanthin significantly reduced the blood pressure and ACE activity in diabetes with hypertension rat. Furthermore, administration of fucoxanthin significantly reduced the hyperglycemic state. The activity of various enzymes in the liver(hexokinase, glucose-6-phosphate dehydrogenase, glucose-6-phosphatase and fructose-1,6-phosphatase)and serum(creatine kinase)were normalized to that of control level. The level of glycogen, glycoprotein component and lipid profile were equivalent to control level by fucoxanthin administration in diabetes with hypertension rats. Fucoxanthin ameliorated the oxidative stress by preserving the endogenous antioxidant levels in diabetes with hypertension rats. Also, the pancreatic histological integrity was similar to that of control level in diabetes with hypertension rats by fucoxanthin treatment. Altogether, fucoxanthin showed dual antidiabetic and antihypertensive activity in vivo.

关键词： Fucoxanthin Diabetes Hypertension Oxidative stress Angiotensin-I-converting enzyme

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Ce-substituted Lithium Ferrite:Preparation and Electrical Relaxation Studies

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Journal of Materials Science & Technology 2014年第4期30卷 335-341页

作者： Viswarupa Mohanty Rajesh Cheruku Lakshmi vijayan G.Govindaraj Department of Physics School of PhysicalChemical and Applied SciencesPondicherry University

Ce-substituted lithium ferrite, Li0.5CexFe2.5-x04 （x = 0, 0.05 and 0.1 ） compositions were synthesized from metal nitrates and citric acid by the solution combustion process by keeping the oxidizer to fuel ratio at unity. The thermal decomposition process was investigated by thermogravimetry-differential thermal analysis, which showed a stable phase formation above 600 ℃. The phase composition and molecular bonding of Li0.5CexFe2.5_x04 were characterized by X-ray powder diffraction analysis and Fourier transform infrared spectroscopy, respectively. An extensive study of electrical relaxation process has been represented with impedance and modulus as a function of frequency at different temperatures. The activation energy obtained from both the formalisms was found to be equal within the error. The dc conductivity and hopping frequency were thermally activated and their activation energies were found to be in the range of 0.69-0.64 eV for x = 0.05. The scaling of modulus and impedance were used to understand the electrical relaxation behaviour of the compositions and they suggest the time temperature superposition principle.

关键词： Lithium ferrite Solution combustion synthesis Inverse spinel Electrical relaxation process and scaling

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Optimization of urease production by Bacillus halodurans PO15:a mangrove bacterium from Poovar mangroves, India

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Marine Life Science & Technology 2020年第2期2卷 194-202页

作者： Vinod Kumar Nathan Jasna vijayan Ammini Parvathi National Institute of Oceanography CSIR CSIR-NIO Regional CentreKochiKerala 682018India School of Chemical and Biotechnology SASTRA UniversityThirumalasamudramThanjavur 613401India

Mangrove ecosystems are one of the most versatile habitats for microorganisms with a high potential for producing a variety of extracellular hydrolytic *** this study,bacteria with urease activity,enzymes that catalyze the hydrolysis of urea into carbon dioxide and ammonia,were isolated from mangrove sediments of Poovar(Trivandrum,India).Bacillus halodurans,strain PO15,isolated in this study with high urease(UA)activity(28 U/ml)was subjected to optimization using a Box-Behnken experimental *** variables included incubation period,pH,inoculation percentage and *** factors identified based on the model were incubation period,pH,incubation temperature,and inoculum percentage;variations in these produced a tenfold increase in UA activity(295.80 U/ml).The specific activity of the purified UA enzyme was 62.34 U/mg and was found to be thermostable(active up to 60℃).UA of *** PO15 has potential for microbial-induced biomineralization with a reduction of free Ca^2+ to about 82.8%±0.17%.The microbialinduced calcium precipitation(MICP)using the UA enzyme will potentially be beneficial in the process of biomineralization as well as for a variety of industrial applications.

关键词： Urease Biomineralization Optimization Mangrove Enzymes

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Support vector regression modeling in recursive just-in-time learning framework for adaptive soft sensing of naphtha boiling point in crude distillation unit

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Petroleum Science 2021年第4期18卷 1230-1239页

作者： Venkata vijayan S Hare Krishna Mohanta Ajaya Kumar Pani Department of Chemical Engineering Birla Institute of Technology and SciencePilaniRajasthan333031India

Prediction of primary quality variables in real time with adaptation capability for varying process conditions is a critical task in process *** article focuses on the development of non-linear adaptive soft sensors for prediction of naphtha initial boiling point(IBP)and end boiling point(EBP)in crude distillation *** this work,adaptive inferential sensors with linear and non-linear local models are reported based on recursive just in time learning(JITL)*** different types of local models designed are locally weighted regression(LWR),multiple linear regression(MLR),partial least squares regression(PLS)and support vector regression(SVR).In addition to model development,the effect of relevant dataset size on model prediction accuracy and model computation time is also *** show that the JITL model based on support vector regression with iterative single data algorithm optimization(ISDA)local model(JITL-SVR:ISDA)yielded best prediction accuracy in reasonable computation time.

关键词： Adaptive soft sensor Just in time learning Regression Support vector regression Naphtha boiling point

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