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Genetic Association of Interferon Gamma Induced Protein-10 (IP-10), <i>CXCL-</i>10 Gene Polymorphisms with TB Pleurisy Susceptibility in South Indian Population

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Open Journal of Immunology 2015年第2期5卷 72-78页

作者： Ghousunnissa Sheikh Venkata Sanjeev Kumar Neela Satya Sudheer Pydi Naveen Chandra Suryadevara Ramulu Gaddam Suman Latha Gaddam Sai Kumar Auzumeedi vijaya lakshmi valluri LEPRA-India Blue Peter Public Health & Research Centre Hyderabad India Government Chest & General Hospital Hyderabad India Bhagwan Mahavir Medical Research Centre Hyderabad India Osmania University Hyderabad India

CXCL-10 known as Interferon gamma-induced protein 10 (IP-10) or small-inducible cytokine 10 is a 8.7 kDa protein, which is secreted in response to IFN-γ by monocytes, endothelial cells and fi-broblasts. It has chemo-attraction for monocytes/macrophages, T cells, NK cells and dendritic cells in promotion of T cell adhesion to endothelial cells. In the present study, we investigated whether polymorphisms in CXCL-10 gene have any role in the manifestation of Tuberculous (TB) pleurisy. Two SNPs in CXCL-10 promoter region (﹣1447A > G and ﹣135G > A) were genotyped in patients with TB Pleurisy (n = 186), Pulmonary TB patients (n = 159) and healthy controls (n = 205) by PCR-RFLP. Disease associations were statistically analyzed by Fisher exact test. At the ﹣135G > A position, the frequencies of genotype GA and allele G were significantly high in TB pleurisy patients compared to healthy controls. While the frequencies of genotype AA and allele A were significantly low in TB pleurisy patients compared to healthy controls. The frequency of haplotype A-G with the combination of 1447A > G and ﹣135G > A was significantly high in TB pleurisy. Our results reveal that genotype GA and allele G at ﹣135G > A position were strongly associated with susceptibility to tuberculous pleurisy. The GA genotype may be a useful genetic marker for early detection of the disease in high risk individuals.

关键词： CXCL-10 Polymorphism Haplotype Susceptibility Tuberculous Pleurisy

Semantic Segmentation of Lumbar Vertebrae Using Meijering U-Net(MU-Net)on Spine Magnetic Resonance Images

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Computer Modeling in Engineering & Sciences 2025年第1期142卷 733-757页

作者： lakshmi S V V Shiloah Elizabeth Darmanayagam Sunil Retmin Raj Cyril Department of Computer Science and Engineering College of Engineering GuindyAnna UniversityChennai600025India Department of Information Technology Madras Institute of TechnologyAnna UniversityChrompetChennai600044India

Lower back pain is one of the most common medical problems in the world and it is experienced by a huge percentage of people *** to its ability to produce a detailed view of the soft tissues,including the spinal cord,nerves,intervertebral discs,and vertebrae,Magnetic Resonance Imaging is thought to be the most effective method for imaging the *** semantic segmentation of vertebrae plays a major role in the diagnostic process of lumbar *** is difficult to semantically partition the vertebrae in Magnetic Resonance Images from the surrounding variety of tissues,including muscles,ligaments,and intervertebral discs.U-Net is a powerful deep-learning architecture to handle the challenges of medical image analysis tasks and achieves high segmentation *** work proposes a modified U-Net architecture namely MU-Net,consisting of the Meijering convolutional layer that incorporates the Meijering filter to perform the semantic segmentation of lumbar vertebrae L1 to L5 and sacral vertebra ***-colour mask images were generated and used as ground truth for training the *** work has been carried out on 1312 images expanded from T1-weighted mid-sagittal MRI images of 515 patients in the Lumbar Spine MRI Dataset publicly available from Mendeley *** proposed MU-Net model for the semantic segmentation of the lumbar vertebrae gives better performance with 98.79%of pixel accuracy(PA),98.66%of dice similarity coefficient(DSC),97.36%of Jaccard coefficient,and 92.55%mean Intersection over Union(mean IoU)metrics using the mentioned dataset.

关键词： Computer aided diagnosis(CAD) magnetic resonance imaging(MRI) semantic segmentation lumbar vertebrae deep learning U-Net model

Design of a robust PID-PSS for an uncertain power system with simplified stability conditions

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Protection and Control of Modern Power Systems 2020年第1期5卷 222-237页

作者： vijaya lakshmi A.S.V Ramalinga Raju Manyala Siva Kumar Mangipudi Department of EEE G.V.P College of Engineering for WomenVisakhapatnamIndia Department of EEE JNTU KakinadaKakinadaIndia Department of EEE Gudlavalleru Engineering CollegeGudlavalleruAndhra PradeshIndia

In a deregulated power system uncertainty exists and lack of sufficient damping can lead to Low FrequencyOscillations (LFO). The problem can be addressed using robust Power System Stabilizers (PSS). In this paper, anoptimal procedure to design a robust PID-PSS using interval arithmetic for the Single Machine Infinite Bus (SMIB)power system is proposed. The interval modelling captures the wide variations of operating conditions in boundsof system coefficients. In the proposed design procedure, simple and new closed loop stability conditions for anSMIB interval system are developed and are used to design an optimum PID-PSS for improving the performance ofan SMIB system. The optimum PID-PSS is attained by tuning the parameters using the FMINCON tool provided inMATLAB. The robustness of the proposed PID-PSS design is validated and compared to other notable methods inthe literature when the system is subjected to different uncertainties. The simulation results and performance errorvalues show the effectiveness of the proposed robust PID-PSS controller.

关键词： Low frequency oscillations Uncertainty Power system stabilizer Robust controller Interval systems

Simultaneous removal of CO_(2), NO_(x) and SO_(x) using single stage absorption column

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Journal of Environmental Sciences 2021年第5期33卷 279-287页

作者： Sriram valluri S.Komar Kawatra Department of Chemical Engineering Michigan Technological UniversityHoughtonMl 49930USA

Capturing flue gases often require multiple stages of scrubbing, increasing the capital and operating costs. So far, no attempt has been made to study the absorption characteristics of all the three gases(NO, SO_(2) and CO_(2)) in a single stage absorption unit at alkaline p H conditions. We have attempted to capture all the three gases with a single wet scrubbing column. The absorption of all three gases with sodium carbonate solution promoted with oxidizers was investigated in a tall absorption column. The absorbance was found to be 100% for CO_(2), 30% for NO and 95% for SO_(2) respectively. The capture efficiency of sodium carbonate solution was increased by 40% for CO_(2) loading, with the addition of oxidizer. Absorption kinetics and reaction pathways of all the three gases were discussed individually in detail.

关键词： Carbon dioxide Nitric oxide Hydrogen peroxide Absorbance Kinetics

Opportunities and challenges in CO_(2) utilization

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Journal of Environmental Sciences 2022年第3期34卷 322-344页

作者： Sriram valluri Victor Claremboux Surendra Kawatra Department of Chemical Engineering Michigan Technological UniversityHoughtonMI 49931USA

CO_(2) utilizations are essential to curbing the greenhouse gas effect and managing the environmental pollutant in an energy-efficient and economically-sound *** paper seeks to critically analyze these technologies in the context of each other and highlight the most important utilization avenues available thus *** review will introduce and analyze each major pathway,and discuss the overall applicability,potential extent,and major limitations of each of these pathways to utilizing CO_(2).This will include the analysis of some previously underreported utilization avenues,including CO_(2) utilization in industrial filtration and the processing of raw industrial materials such as iron and *** core theme of this paper is to seek to treat CO_(2) as a commodity instead of a liability.

关键词： CO_(2)utilization Clean energy Supercritical CO_(2) Electrochemical reduction

Fluorine-containing oxidizers for metal fuels in energetic formulations

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Defence Technology（防务技术） 2019年第1期15卷 1-22页

作者： Siva Kumar valluri Mirko Schoenitz Edward Dreizin New Jersey Institute of Technology Tomsk State University

Fluorine containing oxidizers, primarily polymers, are extensively used in pyrotechnic *** oxidizers are less explored for metalized propellants and explosives despite a potential advantage of substantial heat release combined with gaseous combustion products. This review summarizes different types of fluorinated oxidizers used in energetic formulations or of potential interest for such systems, including gases, polymers, and inorganic compounds. Types of energetic formulations employing metals and fluoropolymers are discussed in more detail, including methods used to prepare composites and resulting salient features of the obtained materials. Laboratory experiments characterizing such materials, in particular, electron microscopy and thermal analysis, are discussed, showing characteristic morphologies and reaction sequences observed in different metal-fluorinated oxidizer composites. Striking similarities are noted in reaction sequences for diverse compositions hinting at possible similarities in the respective reaction mechanisms. Experiments probing ignition and combustion of metal-fluorinated oxidizer composites in laboratory conditions are also reviewed, including impact, flash heating and shock ignition. Finally, some practical performance tests for energetic formulations are described following by a brief discussion of the reaction mechanisms expected to govern ignition and combustion in various metal-fluorinated oxidizer composites. The conclusions are combined with recommendation for future research in the area of reactive metal-fluorinated oxidizer composites.

关键词： Reactive materials Composites Redox reactions Pyrotechnics Propellants Explosives

Palynofloral changes in the Upper Paleozoic and Mesozoic of the Deocha-Pachami area, Birbhum Coalfield, West Bengal, India

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Science China Earth Sciences 2009年第12期52卷 1932-1952页

作者： vijaya Birbal Sahni Institute of Palaeobotany 53 University Road Lucknow 226007 India

The study of Upper Paleozoic and Mesozoic palynomorphs in three boreholes from the Deocha-Pachami area, Birbhum Coalfield, West Bengal, India, has allowed dating of the Talchir, Barakar, Dubrajpur, and Rajmahal formations, and revealed many hiatuses. The lowermost unit, the Talchir Formation, yielded earliest Permian palynomorphs. The Barakar Formation, which includes coal-bearing strata, was previously dated as Early Permian. However, data presented herein indicate an Early Permian to earliest Triassic age for this unit,containing actually the Karharbari, Barakar s.s., Kulti, and Ranigang formations as well as the basal part of the Panchet Formation. The overlying Dubrajpur Formation is Jurassic (Callovian to Tithonian), with an unconformity at its base. The uppermost Dubrajpur Formation is Tithonian-Berriasian. The palynomorphs from the intertrappeans within the Rajmahal Formation suggest an Early Cretaceous age. The revised ages of the Barakar and Dubrajpur formations are of major regional significance. The distribution patterns of spore-pollen may provide a broad spectrum of paleoclimate during Permian, Late Jurassic, and Early Cretaceous times, as there is no record of marine signatures in the study area.

关键词： Talchir to Rajmahal formations Upper Paleozoic Mesozoic spores and pollen biostratigraphy India

Species diversity of birds in mangroves of Kundapura, Udupi District, Karnataka, Southwest Coast of India

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Journal of Forestry Research 2014年第3期25卷 661-666页

作者： vijaya Kumar K.M vijaya Kumara Department of Zoology Bhandarkars’ Arts and Science College Department of Post Graduate Studies and Research in Wildlife and Management Bioscience Block Kuvempu University

We quantified species diversity of birds in mangroves at Kundapura from April-2010 to March-2013. We recorded 79 species of 36 families and 14 orders. Of these 71% are resident species, 22% are residential migrants and 8% are migratory. One endangered species, three near threatened species, and a few occasional visitors were re-corded. Species diversity and abundance of birds were greater during from October through May as there was availability of food, increased vegetation and the arrival of migratory birds. Minimum diversity was recorded from June through September owing to heavy rains, increased flow of water, limited availability of food and return of migratory birds.

关键词： Species, mangroves, birds, threatened migratory

LionRank: lion algorithm-based metasearch engines for re-ranking of webpages

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Science China(Information Sciences) 2018年第12期61卷 65-80页

作者： P.vijaya Satish CHANDER Waljat College of Applied Sciences

Due to the rapid growth of the web, the process of collecting the relevant web pages based on the user query is one of the major challenging tasks in recent days. Hence, it is very complicated for the users to know the most relevant information even though various search engines are widely employed. To deal with users' trouble in identifying the relevant information from the web, we have proposed a meta-lion search engine to capture and analyze the ranking scores of various search engines and thereby, generate the re-ranked score results. Accordingly, LionRank, a lion algorithm-based meta-search engine is proposed for the re-ranking of the web pages. Here, different features like text based, factor based, rank based and classifier based features are used by the underlying search engines. In classifier based feature extraction,we have used the fuzzy integrated extended nearest neighbor(FENN) classifier to include the semantics in feature extraction. Moreover, an intelligent re-ranking process is proposed based on the lion algorithm to fuse the features scores optimally. Finally, the results of the proposed LionRank is analyzed with the web page database collected through four benchmark queries, and the quantitative performance are analyzed using precision, recall, and F-score. From the results, we proved that the proposed LionRank obtained the maximum F-score of 81% as compared with that of existing search engines like QuadRank, Outrank, Google,Yahoo, and Bing.

关键词： web technology meta-search engine feature extraction lion algorithm FENN classifier