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Metamorphic disturbances of magnetite chemistry and the Sm-Nd isotopic system of reworked Archean iron formations from NE Brazil

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Geoscience Frontiers 2022年第5期13卷 227-241页

作者： Joice Dias de Moraes Pedro Cordeiro Eduardo Abrahão Filho Juliana Rezende Oliveira Carlos victor Rios da silva Filho Instituto de Geociências Universidade de Brasília(UnB)70910-900 BrasíliaDFBrazil Department of Mining Engineering Pontifical Catholic University of Chile7820436 SantiagoChile

Iron formations are valuable archives of sedimentary conditions and post-depositional ***,geochemical proxies commonly used to determine genetic characteristics can be variably modified during metamorphism and deformation,hampering their use as records of regional geological *** work focuses on strongly reworked magnetite-quartz-rich rocks from the São Josédo Campestre Massif,one of the oldest fragments of preserved crust in South *** genetic classification of these magnetite-quartz-rich rocks is not straightforward because primary assemblages and textures were variably modified by granulite facies metamorphism during a regional Paleoproterozoic migmatization *** address genetic ambiguities,we analyzed their magnetite and pyroxene chemistry,wholerock geochemistry,and Sm-Nd *** chemistry indicates that pyroxene-poor iron formations(Type B)are low in trace elements such as Ti,Al,V,and Mn,suggesting a chemical similarity to iron formations *** contrast,magnetites from pyroxene-enriched Type A iron formations are rich in trace elements and more akin to magnetite crystallized from higher temperature systems,such as skarn and ***^(147)Sm/^(144)Nd of these rocks show substantial variation even at the outcrop scale,indicating a locally-controlled,highly heterogeneous mixture of Archean,Paleoproterozoic,and Neoproterozoic ***,our geochemical tools point out to heterogenous signatures of these magnetitequartz rocks and proxies compatible with both low and high-temperature conditions and age of deposition spanning sources from the Archean to the *** interpret that the studied São Josédo Campestre magnetite-quartz rocks represent Archean iron formations with original magnetite chemistry and isotopic signatures variably modified by metamorphism and by at least one deformation-related hydrothermal *** results contrast with similar examples from China and Greenland where iron formation

关键词： Metamorphic disturbances of magnetite chemistry and the Sm-Nd isotopic system of reworked Archean iron formations from NE Brazil

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State and perspectives on flavonoid neuroprotection against aminochrome-induced neurotoxicity

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Neural Regeneration Research 2021年第9期16卷 1797-1798页

作者： victor silva Juan Segura-Aguilar Laboratory of Neurochemistry and Cell Biology Department of Biochemistry and BiophysicsInstitute of Health SciencesFederal University of Bahia40110-100SalvadorBahiaBrazil Molecular and Clinical Pharmacology ICBMFaculty of MedicineUniversity of ChileChile

Parkinson's disease(PD) motor symptoms are induced by the loss of dopaminergic neurons containing neuromelanin in the nigrostriatal system. The exact mechanism that triggers the degeneration of the nigrostriatal neurons is still unknown but there is general consensus in the scientific community that mitochondrial dysfunction, alpha-synuclein aggregation to neurotoxic oligomers, protein degradation dysfunction of both lysosomal and proteasomal systems, endoplasmic reticulum stress.

关键词： degeneration reticulum aggregation

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ENSO impacts on litter stocks and water holding capacity in secondary forests in eastern Amazonia

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Journal of Forestry Research 2024年第1期35卷 83-89页

作者： Julia Isabella de Matos Rodrigues Walmer Bruno Rocha Martins victor Pereira de Oliveira Myriam Suelen da silva Wanzerley Hélio Brito dos Santos Júnior Francisco de Assis Oliveira Graduate Program in Forestry Sciences Av.Presidente Tancredo Neves2501BelémPará66077-530Brazil Federal Rural University of Amazonia Av.Presidente Tancredo Neves2501BelémPará66077-530Brazil Federal Rural University of Amazonia Tv.Pau-AmareloCapitão PoçoPará68650-000Brazil National Institute of Amazonia Research Av.Constelação Cruzeiro do SulManausAmazonas 69060-062Brazil

Among the impacts of climate change,there is the intensification of phenomena such as the El Niño South-ern Oscillation(ENSO)responsible for El Niño and La Niñ***,understanding their effects on the functional pro-cesses of forests is ***,this study evaluated the effects of ENSO on litter stock and water holding capac-ity(WHC)in a successional forest in eastern *** occurred in periods with the most rainfall in El Niño(2019)and least in La Niña(2021)*** permanent plots were used to sample *** effects were evident for WHC,higher during El Niñ***,this influence was not clear for litter,as only in the rainy season effects were *** was a positive correlation of WHC with precipitation and humidity,while litter stocks were negatively correlated with temperature and wind *** the subject of this study requires long-term assessments,preliminary results suggests that,depending on the intensity of ENSO,forest functional processes can be strongly impacted and *** conclusion reinforces warnings by the scientific community about the impacts of climate change on the maintenance of litter stocks,decomposition and,consequently,the biogeochemical cycle and essential ecosystem services for the maintenance of Amazonia *** need to develop long-term research to understand the effects of climatic change on litter stocks and water holding capacity is highlighted,especially in Amazonia.

关键词： Seasonality Climate change Succession ecosystem Biogeochemical cycle Amazonia biodiversity

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Cerebral and muscle tissue oxygenation during exercise in healthy adults: A systematic review

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Journal of Sport and Health Science 2024年第4期13卷 459-471,F0003页

作者： Diego Orcioli-silva victor Spiandor Beretta Paulo Cezar Rocha Santos Felipe Marroni Rasteiro Anita Brum Marostegan Rodrigo Vitorio Claudio Alexandre Gobatto Fulvia Barros Manchado-Gobatto Laboratory of Applied Sport Physiology(LAFAE) School of Applied Sciences(FCA)University of Campinas(UNICAMP)Limeira 13484-350Brazil Posture and Gait Studies Laboratory(LEPLO) Institute of BiosciencesSao Paulo State University(UNESP)Rio Claro 13506-900Brazil Physical Education Department School of Technology and SciencesSao Paulo State University(UNESP)Presidente Prudente 19060-900Brazil Department of Computer Science&Applied Mathematics Weizmann Institute of ScienceRehovot 7610001Israel Center of Advanced Technologies in Rehabilitation Sheba Medical CenterRamat Gan 5265601Israel Department of Sport Exercise and RehabilitationNorthumbria UniversityNewcastle upon Tyne NE18STUK

Background:Near-infrared spectroscopy(NIRS)technology has allowed for the measurement of cerebral and skeletal muscle oxygenation simultaneously during *** this technology has been growing and is now successfully used in laboratory and sports settings,this systematic review aimed to synthesize the evidence and enhance an integrative understanding of bloodﬂow adjustments and oxygen(O_(2))changes(i.e.,the balance between O_(2) delivery and O_(2) consumption)within the cerebral and muscle systems during ***:A systematic review was conducted using PubMed,Embase,Scopus,and Web of Science databases to search for relevant studies that simultaneously investigated cerebral and muscle hemodynamic changes using the near-infrared spectroscopy system during *** review considered manuscripts written in English and available before February 9,*** step of screening involved evaluation by 2 inde-pendent authors,with disagreements resolved by a third *** Joanna Briggs Institute Critical Appraisal Checklist was used to assess the methodological quality of the ***:Twenty studies were included,of which 80%had good methodological quality,and involved 290 young or middle-aged *** types of exercises were used to assess cerebral and muscle hemodynamic changes,such as cycling(n=11),treadmill(n=1),knee extension(n=5),isometric contraction of biceps brachii(n=3),and duet swim routines(n=1).The cerebral hemodynamics anal-ysis was focused on the frontal cortex(n=20),while in the muscle,the analysis involved vastus lateralis(n=18),gastrocnemius(n=3),biceps brachii(n=5),deltoid(n=1),and intercostal muscle(n=1).Overall,muscle deoxygenation increases during exercise,reaching a plateau in voluntary exhaustion,while in the brain,oxyhemoglobin concentration increases with exercise intensity,reaching a plateau or declining at the exhaustion ***:Muscle and cerebral oxygenation respond differently to exercise,with muscle

关键词： Near-infrared spectroscopy Hemodynamic Blood flow Brain Muscle metabolism

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Oncolytic virus therapy in cancer: A current review

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World Journal of Virology 2021年第5期10卷 229-255页

作者： Jonathan Santos Apolonio Vinicius Lima de Souza Goncalves Maria Luisa Cordeiro Santos Marcel silva Luz Joao victor silva Souza Samuel Luca Rocha Pinheiro Wedja Rafaela de Souza Matheus Sande Loureiro Fabricio Freire de Melo Universidade Federal da Bahia Instituto Multidisciplinar em SaudeVitoria da Conquista 45029-094BahiaBrazil Universidade Estadual do Sudoeste da Bahia Campus Vitoria da ConquistaVitoria da Conquista 45083-900BahiaBrazil

In view of the advancement in the understanding about the most diverse types of cancer and consequently a relentless search for a cure and increased survival rates of cancer patients,finding a therapy that is able to combat the mechanism of aggression of this disease is extremely ***,oncolytic viruses(OVs)have demonstrated great benefits in the treatment of cancer because it mediates antitumor effects in several *** can be used to infect cancer cells,especially over normal cells,to present tumor-associated antigens,to activate“danger signals”that generate a less immune-tolerant tumor microenvironment,and to serve transduction vehicles for expression of inflammatory and immunomodulatory *** success of therapies using OVs was initially demonstrated by the use of the genetically modified herpes virus,talimogene laherparepvec,for the treatment of *** this time,several OVs are being studied as a potential treatment for cancer in clinical ***,it is necessary to be aware of the safety and possible adverse effects of this therapy;after all,an effective treatment for cancer should promote regression,attack the tumor,and in the meantime induce minimal systemic *** this manuscript,we will present a current review of the mechanism of action of OVs,main clinical uses,updates,and future perspectives on this treatment.

关键词： Oncolytic viruses Antitumor response Tumor lysis Tumor cells Mechanism Therapy

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Highlighting COVID-19:What the imaging exams show about the disease

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World Journal of Radiology 2021年第5期13卷 122-136页

作者： Lorena Sousa de Carvalho Ronaldo Teixeira da silva Júnior Bruna Vieira silva Oliveira Yasmin silva de Miranda Nara Lúcia Fonseca Rebouças Matheus Sande Loureiro Samuel Luca Rocha Pinheiro Regiane Santos da silva Paulo victor silva Lima Medrado Correia Maria José Souza silva Sabrina Neves Ribeiro Filipe Antônio França da silva Breno Bittencourt de Brito Maria Luísa Cordeiro Santos Rafael Augusto Oliveira Sodré Leal Márcio Vasconcelos Oliveira Fabrício Freire de Melo Department of Instituto Multidisciplinar em Saúde Universidade Federal da BahiaVitória da Conquista 45029-094BahiaBrazil

Coronavirus disease 2019(COVID-19),a global emergency,is caused by severe acute respiratory syndrome coronavirus *** gold standard for its diagnosis is the reverse transcription polymerase chain reaction,but considering the high number of infected people,the low availability of this diagnostic tool in some contexts,and the limitations of the test,other tools that aid in the identification of the disease are *** this scenario,imaging exams such as chest X-ray(CXR)and computed tomography(CT)have played important *** is useful for assessing disease progression because it allows the detection of extensive consolidations,besides being a fast and cheap *** the other hand,CT is more sensitive for detecting lung changes in the early stages of the disease and is also useful for assessing disease *** note,ground-glass opacities are the main COVID-19-related CT *** emission tomography combined with CT can be used to evaluate chronic and substantial damage to the lungs and other organs;however,it is an expensive *** ultrasound(LUS)has been shown to be a promising technique in that context as well,being useful in the screening and monitoring of patients,disease classification,and management related to mechanical ***,LUS is an inexpensive alternative available at the ***,magnetic resonance imaging,although not usually requested,allows the detection of pulmonary,cardiovascular,and neurological abnormalities associated with ***,it is important to consider the challenges faced in the radiology field in the adoption of control measures to prevent infection and in the follow-up of post-COVID-19 patients.

关键词： SARS-CoV-2 COVID-19 Pneumonia Pandemic Radiology Tomography

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Direct observation of the CO_(2) formation and C–H consumption of carbon electrode in an aqueous neutral electrolyte supercapacitor by in-situ FTIR and Raman

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Journal of Energy Chemistry 2022年第8期31卷 488-496,I0013页

作者： Murilo M.Amaral victor Y.Yukuhiro Rafael Vicentini Alfredo C.Peterlevitz Leonardo M.Da silva Pablo Fernandez Hudson Zanin Advanced Energy Storage Division State University of Campinas13083-852Av.Albert Einsten 400CampinasSPBrazil Chemistry Institute State University of Campinas13083-970Josue de Castro StreetCampinasSPBrazil Department of Chemistry Laboratory of Fundamental and Applied ElectrochemistryFederal University of Jequitinhonha and Mucuri’s ValleyRodovia MGT 367km 5835000Alto da Jacuba39100-000DiamantinaMGBrazil Center for Innovation on New Energies University of Campinas13083-841 CampinasSão PauloBrazil

Electrical double-layer capacitors(EDLCs)consist of energy storage devices that present high-power and moderate energy *** electrolyte and electrode physicochemical properties are crucial for improving their overall energy storage ***,the stability of the EDLCs’materials is the primary focus of this *** energy storage depends on the specific capacitance,and also on the square of the maximum capacitive cell voltage(UMCV).Thus,electrodes with high specific surface area(SSA)and electrolytes with excellent electrochemical stability are commonly reported in the *** electrolytes are safer and green devices compared to other organic-based *** the other hand,their UMCVis reduced compared to other electrolytes(e.g.,organic-based and ionic liquids).In this sense,spanning the UMCVfor aqueous-based electrolytes is a’hot topic’***,the lack of protocols to establish reliable UMCVvalues has culminated in the publishing of several conflicting ***,we confirm that multiwalled carbon nanotubes(MWCNTs)housed in cells degrade and produce CO_(2) under abusive polarisation *** is probed by employing electrochemical techniques,in-situ FTIR and in-situ Raman *** these considerations,the current study uses spectro-electrochemical techniques to support the correct determination of the electrode and electrolyte stability conditions as a function of the operating electrochemical parameters.

关键词： Electrode and electrolyte stabilities In-situ FTIR CO_(2)formation Carbon degradation Supercapacitor Aqueous electrolytes Carbon nanotubes

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Novel virtual nasal endoscopy system based on computed tomography scans

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Virtual Reality & Intelligent Hardware 2022年第4期4卷 359-379页

作者： Fábio de O.SOUSA Daniel S.da silva Tarique da S.CAVALCANTE Edson C.NETO victor JoséT.GONDIM Ingrid C.NOGUEIRA Auzuir Ripardo de ALEXANDRIA victor Hugo C.de ALBUQUERQUE Federal Institute of Ceará-IFCE Telecommunication Engineering ProgramBrazil Graduate Program on Teleinformatics Engineering Federal University of CearáFortaleza/CEBrazil Centro Universitário Christus-UniChristus Brazil Centro Universitário Sete de Setembro-Uni7 Brazil

Background Currently,many simulator systems for medical procedures are under *** systems can provide new solutions for training,planning,and testing medical practices,improve performance,and optimize the time of the ***,to achieve the best results,certain premises must be followed and applied to the model under development,such as usability,control,graphics realism,and interactive and dynamic *** This study presents a system for simulating a medical examination procedure in the nasal cavity for training and research purposes,using a patient′s accurate computed tomography(CT)as a *** pathologies that are used as a guide for the development of the system are ***,an overview of current studies covering bench medical mannequins,3D printing,animals,hardware,software,and software that use hardware to boost user interaction,is ***,a comparison with similar state-of-the-art studies is *** The main result of this work is interactive gamification techniques to propose an experience of simulation of an immersive exam by identifying pathologies present in the nasal cavity such as hypertrophy of turbinates,septal deviation adenoid hypertrophy,nasal polyposis,and tumor.

关键词： Virtual nasal endoscopy Computed tomography Gamification Endoscopy teaching

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Alternative Method to Evaluate Performance Improvement Rate in Athletics Middle Distance Events

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Journal of Science in Sport and Exercise 2022年第2期4卷 128-134页

作者： Lucas Pinheiro Barbosa Patrick Aguiar Santos Samuel silva Aguiar Herbert Gustavo Simões Pantelis Theodoros Nikolaidis Beat Knechtle Caio victor Sousa Graduate Program in Physical Education Catholic University of BrasíliaBrasíliaDFBrazil Exercise Physiology Laboratory NikaiaGreece School of Health and Care Sciences University of West AtticaAthensGreece Medbase St.Gallen Am Vadianplatz Vadianstrasse 269001 St.GallenSwitzerland Institute of Primary Care University of ZurichZurichSwitzerland Bouve College of Health Sciences Northeastern UniversityBostonMAUSA

Purpose The aims of this study were to propose an alternative method to assess an optimal performance improvement rate(PIR)that would be used as a tool for coaches and elite athletes willing to reach their personal best,mainly those seeking for national,continental or even world record(WR)in middle-distance *** further compared the improvement rate of women *** of the top-10 ranked athletes in the IAAF running these middle-distance events Method The top 10 athletes in the IAAF ranking of 800 m,1500 m,and 3000 m events for each sex were assessed for their history of race times before achieving their personal record(PR).The difference between PR(‘actual’season)and the best race time in the last season was defined as the 1st season improvement rate(1-SIR),whereas the average improvement rate in the last and preceding seasons was the multi-season improvement rate(M-SIR).1-SIR and M-SIR were calculated for each *** There were sex differences in the 1500 m with a large effect size(d=−0.746)in 1-SIR(P=0.001)and very large(d=−2.249)in M-SIR(P=0.001).Women improved more than men before the PR/WR achievements in the 800 m and 1500 m events(P=0.001)and had similar improvement rates before performing PR/WR in 3000 m events(P=0.533).Conclusion Women improve more before PR/WR achievement in 800 m and 1500 m ***,in the 3000 m men and women have similar improvement rates in previous seasons before the PR/WR achievement.

关键词： Performance Running Track-and-field Middle-distance Athletics

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Physical fitness level and the risk of severe COVID-19:A systematic review

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Sports Medicine and Health Science 2023年第3期5卷 174-180页

作者： Fortunato JoséCardoso David Romeiro victor JoséRoberto da silva Angélica C.Guimarãaes Carla Adriane Leal Michelle Ribeiro Taveira João Guilherme Alves Departament of Hepatology Instituto de Medicina Integral Prof.Fernando Figueira(IMIP)RecifePernambucoBrazil Graduate Unit Universidade de Pernambuco(UPE)RecifePernambucoBrazil Department of Pediatrics Hospital Dom MalanPetrolinaPernambucoBrazil

To verify systematically the association between the status of physical fitness and the risk of severe Coronavirus disease 2019(COVID-19).This systematic review is in accordance with the Preferred Reporting Items for Systematic Review and Meta Analyses(PRISMA)statement and the eligibility criteria followed the Population,Intervention,Comparison,Outcomes and Study(PICOS)***,Embase,SciELO and Cochrane electronic databases were *** studies that explored the relationship between the pattern of physical fitness and COVID-19 adverse outcomes(hospitalization,intensive care unit admission,intubation,or mortality),were *** quality of the studies was assessed by the specific scale of the Newcastle-Ottawa Scale.A total of seven observational studies were identified in this systematic review;13468 patients were included in one case-control study,two cohort studies,and four cross-sectional *** studies reported an inverse association between high physical fitness and severe COVID-19(hospitalization,intensive care admission,or mortality).Only some studies reported comorbidities,especially obesity and cardiovascular disorders,but the results remained unchanged after controlling for *** quality of the seven studies included was moderate according to the Newcastle-Ottawa Quality Assessment *** methodological heterogeneity of the studies included did not allow a meta-analysis of the *** conclusion,higher physical fitness levels were associated with lower risk of hospitalization,intensive care admissions,and mortality rates among patients with COVID-19.

关键词： Physical fitness COVID-19 Hospitalization Intensive care units Mortality

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