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Journal of Bionic Engineering 2024年第4期21卷 1987-1999页

作者： Anbazhagan Rajesh venkatesh sri hariny Arunachalam Sumathi School of Civil Engineering SASTRA Deemed to be UniversityThirumalaisamudramThanjavurTamilnadu613401India

Sustainable cement-based concrete materials are primarily used for construction,among which vermiculite as lightweight fine aggregate gains more future development ***,a bacterial solution was sprayed over vermiculite and wrapped using calcium sulphoaluminate(CSA)cement to replace with fine aggregate in ***,based on a preliminary test on compressive strength results,10%of Ground Granulated Blast Furnace Slag(GGBS)and a healing solution proportion of 9:1 was selected for preparing self-healing *** fine aggregate was replaced in concrete using vermiculite in 0%,5%,10%and 15%and the findings suggest that bacterial vermiculite replacement should be at most 5%to achieve better results in strength and durable *** strength enhancement observed for compressive strength,strength regain,split tensile strength,flexural strength,and ultrasonic pulse velocity were 29.22%,45.5%,34.02%,28.03%and 41.4%*** crack healing at 7,14 and 28 days of BIVC was 38.23%,58.82%and 79.41%,which is 3–4%lower than internal crack *** analysis by Scanning Electron Microscopy(SEM),X-Ray Diffractometer(XRD),and Energy Dispersive Spectroscopy(EDS)reveals the existence of calcite,and it was formed due to the bio-mineral action of bacteria with available nutrients in sustainable concrete.

关键词： Bacillus tropicus Vermiculite Ground granulated blast furnace slag Mechanical properties Durable properties Crack healing Microstructural characterization

Treatment of hepatitis C in children and adolescents:how far have we reached?

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World Journal of Pediatrics 2023年第2期19卷 107-119页

作者： Vybhav venkatesh Keerthivasan Seetharaman Neha Anushree Department of Gastroenterology and Hepatobiliary Sciences IMS and SUM HospitalSOA UniversityBhubaneswarIndia Department of Pediatrics Sri Manakula Vinayagar Medical College and HospitalPuducherryIndia Department of Pediatrics Command Hospital-Southern CommandPune411040India

Background Hepatitis C virus(HCV)infection is a global public health problem and also generates a significant case load in children and *** the introduction of directly acting antivirals(DAA),the treatment and care of HCV-infected patients have progressed *** available treatment options in children are limited,and this review aims to provide an overview of treatment of HCV infection in children and adolescents with the current available DAA *** sources This comprehensive review was undertaken after searching the PubMed/Medline and Embase databases for the available up-to-date literature on pediatric HCV infection and treatment using hepatitis C virus infection/HCV,directly acting antivirals/DAA,natural history,treatment,pediatrics,children,and adolescents as *** Combination therapies with highly effective DAA regimes,such as sofosbuvir/ledipasvir,sofosbuvir/velpatasvir,glecaprevir/pibrentasvir,sofosbuvir/daclatasvir,sofosbuvir/ribavirin and others,are available for use in *** of the DAA regimens have either received or are pending to receive regulatory approval by different medical/drug agencies for use in children and ***-genotypic regimens are also available in children and adolescents,and these regimens can be used while skipping genotype *** The literature on different DAA regimens for use in children shows that these regimens have higher cure rates with minimal side effects and shorter duration of therapy.

关键词： Children Directly acting antivirals Hepatitis C

Location Prediction for Improved Human Safety at Complex Environments

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Computers, Materials & Continua 2022年第6期71卷 5219-5234页

作者： S.G.Siddharth G.M.Tamilselvan C.venkatesh Department of Electrical and Electronics Engineering Angel College of Engineering and TechnologyTirupurTamilnaduIndia Department of Electronics and Communication Engineering Sri Krishna College TechnologyCoimbatoreTamilnaduIndia Department of Electronics and Communication Engineering KGISL Institute of TechnologyCoimbatoreTamilnaduIndia

In underground operation,primary consideration is *** recent decades,for minimizing accident and for preventing major economic losses and casualties,wireless sensors are used by various large mineral countries through early *** Improved DV-Hop Localization Algorithm(IDVHLA)is used in existing works for doing ***,accurate anchor node detection is impossible in existing works with the malicious nodes presence,where there won’t be any accurate sharing of anchor node’s location *** case of emergency situation,faster communication is a highly complex one.A technique calledModified Distance Vector Hop based Multipath Routing Protocol(MDVHMRP)is introduced in this proposed research work for resolving *** this work,to detect anchor node position,a Modified Distance Vector Hop technique is *** research work considers time taken and session time for computing neighbour node’s presence in addition to hop count *** nodes presence can be avoided by considering session time in neighbour node presence *** alert message are send by people in emergency crisis to sever in initial *** Dynamic Source Routing(DSR)routing protocol is used for doing immediate route path *** case of route path failure,for ensuring uninterrupted communication and faster communication,this work introduces amulti path *** distance vector hop technique is used for predicting anchor node location information and predicted information will be *** NS2 simulation environment,overall evaluation of this research work is carried *** compared with available techniques,localization accuracy is enhanced by proposed technique as proven in experimental results.

关键词： Distance vector hop uninterrupted communication multipath routing anchor node localization

Polarized Ketene Dithioacetals-Versatile Synthons for Different Heterocycles

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Chinese Journal of Chemistry 2012年第8期30卷 1886-1892页

作者： venkatesh B.C. Premakumari C. Padmaja A. Padmavathi V. Department of Chemistry Sri Venkateswara UniversityTirupati-517502Andhra PradeshIndia

The reactivity of polarized ketene dithioacetals to develop a variety of heterocycles under different conditions was studied.

关键词： polarized ketene dithioacetals thienothiophenes bis-benzoxazolyl/benzothiazolyl/benzimidazolyl-pyrazolidine diones/isoxazolidinediones/pyrimidinetriones/thioxopyrimidinediones cyclocondensation

GC-MS analysis of Cocus nucifera flower extract and its effects on heterogeneous symptoms of polycystic ovarian disease in female Wistar rats

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Chinese Journal of Natural Medicines 2014年第9期12卷 677-684页

作者： V.Soumya Y.Indira Muzib P.venkatesh K.Hariprasath Department of Pharmaceutical Technology Sri Padmavathi Mahila Viswavidyalayam Tirupathi- 517502 Andhra Pradesh India Department of Pharmaceutical Chemistry Sir C.R.Reddy College of Pharmaceutical Sciences

AIM: To evaluate the effect of Cocus nucifera L. flowers in reducing the major multiple symptoms of letrozole-induced polycystic ovarian disease(PCOD) in female rats. METHOD: Female, virgin Wistar rats were treated with letrozole(1 mg/kg body wt) to induce PCOD, and after 21 days of induction rats were administered orally with 100 and 200 mg·kg-1 of Cocus nucifera flower aqueous extract, respectively. Estrus cycle and blood sugar were monitored once a week throughout the study. After scarification, various biochemical parameters, such as antioxidant status(superoxide dismutase(SOD) and glutathione reductase(GSH)) of the uterus homogenate, lipid profile(total cholesterol(TC), high density lipoprotein(HDL), low density lipoprotein(LDL), and triglycerides(TG)) of the serum were determined. Weights of the uterus and ovaries were separately monitored. The characteristics of changes in the ovary were evaluated by histopathological studies. RESULTS: GC-MS analysis of the aqueous extract showed the presence of volatile and pharmacologically active phytoconstituents. C. nucifera flower extract-treated groups showed estrus cyclicity and increased uterus weight which indicates the estrogenic effect. The improved blood sugar level, ideal lipid profile, good antioxidant status, and histopathology results revealed the recovery from poly cystic ovaries. CONCLUSION: The results indicate that C. nucifera flower is a potential medicine for the treatment of PCOD and this study supports the traditional uses of C. nucifera flower.

关键词： flower uterus superoxide ovary monitored virgin cycle Female glutathione volatile

TYMS gene 5'-and 3'-untranslated region polymorphisms and risk of non-syndromic cleft lip and palate in an Indian population

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The Journal of Biomedical Research 2015年第4期29卷 337-339页

作者： Jyotsna Murthy venkatesh Babu G. L.V.K.S.Bhaskar Department of Biomedical Sciences Sri Ramachandra University Department of Plastic Surgery Sri Ramachandra University

Dear Editor： Increased homocysteine levels due to vitamin B6 or B12 deficiency or genetic defects in folate pathway genes are associated with an increased incidence of non-syndromic cleft lip with or without cleft palate （NSCLP）tlj. Thymidylate synthase （TS） is a folate-dependent enzyme that catalyzes methylation of 2＇-deoxyuridine-5＇-monophosphate （dUMP） to 2＇-deox- ythymidine-5＇-monophosphate （dTMP）, a rate-limiting step in DNA synthesis,

关键词： TYMS gene 5 untranslated region polymorphisms and risk of non-syndromic cleft lip and palate in an Indian population and 3 gene

Effect of Flow Field Geometry on Hydrodynamics of Flow in Redox Flow Battery

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Energy Engineering 2022年第1期119卷 201-217页

作者： M.Narendra Kumar S.Manoj Kumar G.C.Vijayakumar K.Kadirgama M.Samykano Krishna venkatesh H.B.Murlidhara Center for Incubation Innovation Research and Consultancy(CIIRC)Jyothy Institute of TechnologyBangalore560082KarnatakaIndia Department of Mechanical Engineering Jyothy Institute of TechnologyBangalore560082KarnatakaIndia Faculty of Mechanical and Automotive Engineering Technology University Malaysia PahangPahang26600Malaysia Centre for Automotive Engineering Universiti Malaysia PahangPahang26600Malaysia College of Engineering Universiti Malaysia PahangPahang26600Malaysia

This study computationally investigates the hydrodynamics of different serpentine flow field designs for redox flow batteries,which considers the Poiseuille flow in the flow channel and the Darcy flow porous *** Fluid Dynamics(CFD)results of the in-house developed code based on Finite Volume Method(FVM)for conventional serpentine flow field(CSFF)agreed well with those obtained via *** deviation for pressure drop(ΔP)was less than 5.1%for all the flow rates,thus proving the present CFD analysis’s validity on the modified variation of serpentine flow *** serpentine flow field-2(MSFF2)design provided least pressure drop across the channel and maximum velocity penetration across the porous substrate when compared to the other *** increases its wetting ability,which is very important in terms of mass transfer over potential for electrochemical reaction happening in the porous substrate to achieve effective electrochemical cell performance.

关键词： Pressure drop velocity distribution serpentine flow field porous substrate redox flow battery

Expression Analysis of Aldo-Keto Reductase 1 (AKR1) in Foxtail Millet (Setaria italica L.) Subjected to Abiotic Stresses

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American Journal of Plant Sciences 2016年第3期7卷 500-509页

作者： Tanguturi Venkata Kirankumar Kalaiahgari Venkata Madhusudhan Ambekar Nareshkumar Kurnool Kiranmai Uppala Lokesh Boya venkatesh Chinta Sudhakar Plant Molecular Biology Laboratory Department of Botany Sri Krishnadevaraya University Anantapuramu India

Foxtail millet (Setaria italica L.) is a drought-tolerant millet crop of arid and semi-arid regions. Aldo-keto reductases (AKRs) are significant part of plant defence mechanism, having an ability to confer multiple stress tolerance. In this study, AKR1 gene expression was studied in roots and leaves of foxtail millet subjected to different regimes of PEG- and NaCl-stress for seven days. The quantitative Real-time PCR expression analysis in both root and leaves showed upregulation of AKR1 gene during PEG and salt stress. A close correlation exits between expression of AKR1 gene and the rate of lipid peroxidation along with the retardation of growth. Tissue-specific differences were found in the AKR1 gene expression to the stress intensities studied. The reduction in root and shoot growth under both stress conditions were dependent on stress severity. The level of lipid peroxidation as indicated by MDA formation was significantly increased in roots and leaves along with increased stress levels. Finally, these findings support the early responsive nature of AKR1 gene and seem to be associated at least in part with its ability to contribute in antioxidant defence related pathways which could provide a better protection against oxidative stress under stress conditions.

关键词： Aldo-Keto Reductase Lipid Peroxidation Reactive Carbonyls Cellular Homeostasis Plant Abiotic Stress Response

Pb-Stress Induced Oxidative Stress Caused Alterations in Antioxidant Efficacy in Two Groundnut (<i>Arachis hypogaea</i>L.) Cultivars

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Agricultural Sciences 2015年第10期6卷 1283-1297页

作者： Ambekar Nareshkumar Gounipalli Veeranagamallaiah Merum Pandurangaiah Kurnool Kiranmai Vennapusa Amaranathareddy Uppala Lokesh Boya venkatesh Chinta Sudhakar Plant Molecular Biology Unit Department of Botany Sri Krishnadevaraya University Anantapur India

Lead (Pb) is an important environmental pollutant extremely toxic to plants and other living organisms including humans. To assess Pb phytotoxicity, a pot culture experiment was carried out using two groundnut cultivars (Arachis hypogaea L. cultivar K6 and cultivar K9) on plant growth, ROS levels, lipid peroxidation, and antioxidant metabolism using biochemical, histochemical methods. Plants were grown in pots for 14 days, in the botanic garden, and subjected to Pb-stress (0, 100, 200, 400 and 800 ppm) by adding Pb (NO3)2 solution and further allowed to grow for 10 days. The results showed that cultivar K6 registered lower Pb accumulation than cultivar K9, however, localization of Pb was greater in roots than leaves in both groundnut cultivars. The Pb-stress results in an increase in free radicals (O2?- and H2O2) generation in both groundnut cultivars, but more significantly in cultivar K9 than K6. Pb-stress also caused significant changes in the rate of peroxidation as shown in the levels of malondialdehyde (MDA) content in roots and leaves of both groundnut cultivars. Free proline, ascorbic acid (AsA) and non-protein thiol (NP-SH) contents were increased in cultivar K6 due to Pb-stress, but less in cultivar K9. Pb treated plants showed increased levels of antioxidant enzymes such as superoxide dismutase (SOD), guaiacol peroxidase (GPX), ascorbate peroxidase (APX) glutathione reductase (GR) and glutathione S-transferase (GST). Isozyme band intensities of SOD, GPX and APX were more consistent with the respective changes in antioxidative enzyme activities. These results indicate that cultivar K6 possesses greater tolerance potential for Pb toxicity than cultivar K9.

关键词： Groundnut (Arachis hypogaea L.) Pb-Stress Oxidative Stress Antioxidant Enzymes Non-Protein Thiols Reactive Oxygen Species

Expression Analysis of WRKY Transcription Factor Genes in Response to Abiotic Stresses in Horsegram (Macrotyloma uniflorum (Lam.) Verdc.)

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American Journal of Molecular Biology 2016年第4期6卷 125-137页

作者： Kurnool Kiranmai Lokanadha Rao Gunupuru Ambekar Nareshkumar Vennapusa Amaranatha Reddy Uppala Lokesh Merum Pandurangaiah Boya venkatesh Tanguturi Venkata Kirankumar Chinta Sudhakar Department of Botany Sri Krishnadevaraya University Anantapur India Molecular Plant-Microbe Interactions Laboratory University College Dublin Dublin Ireland Department of Crop Physiology GKVK Bangalore India Shenzhen Research Institute The Chinese University of Hong Kong Shenzhen China

Drought and salt stress are two major environmental constraints that limit the productivity of agriculture crops worldwide. WRKY transcription factors are the plant-specific transcription factors that regulate several developmental events and stress responses in plants. The WRKY domain is defined by a 60-amino acid conserved sequence named WRKYGQK at N-terminal and a Zinc Finger-like motif at the C-terminal. WRKY genes are known to respond several stresses which may act as negative or positive regulators. The function of most of the WRKY transcription factors from non-model plants remains poorly understood. This investigation shows the expression levels of eight WRKY transcription factor genes from horsegram plant under drought and salt stress conditions. The increase in mRNA transcript levels of WRKY transcription factor genes was found to be high in drought stressed plants compared to salt-stressed plants. The levels of MDA which indicates the lipid peroxidation were less in drought stress. More ROS is produced in salt stress conditions compared to drought. The results show that the expression of WRKY transcription factors in drought stress conditions is reducing the adverse effect of stress on plants. These results also suggest that, during abiotic stress conditions such as drought and salt stress, WRKY transcription factors are regulated at the transcription level.

关键词： Drought Salt Lipid Peroxidation Plant Abiotic Stress qRT-PCR Reactive Oxygen Species WRKY