检索结果-南通市图书馆

世界核心医学期刊文摘（皮肤病学分册） 2005年第3期1卷 46-46页

作者： Palmer R.A. vande pas c.b. campalani E. 崔荣 Palmer St. John's Institute of Dermatology Division of Skin Sciences St. Thomas'Hospital So uth Wing Block 7 London SE1 7EH United Kingdom Dr.

background: The severity of polymorphic light eruption (PLE)-is highly vari able. The results of studies of the prevalence, pathogenesis, provocation and tr eatment of PLE may be highly dependent on the severity of disease in the patient s studied. Objectives: To produce a simple, valid and reproduc.b.e method to ass ess the severity of PLE, Patients and methods: Eighty patientswere asked about t he PLE they had experienced during the preceding 12 months, using a standardized interview comprising 16 questions. The answer to each question received a score . A PLE Severity Index (PLESI) was formulated, consisting of 10 questions, with a possible total score of 2- 100. The internal consistency of the PLESI (the ex tent to which the responses to different questions correlated with each other) w as assessed by reliability analysis, using cronbach’s method. Twenty patients were re-interviewed 7- 27 days later to assess the repeatability of the PLESI . The ease of provocation of PLE by exposure at 24- h intervals to solar-simu lated radiation was assessed on a five-point scale in nine of the 80 subjects (the EOPSSR score). Results The value of cronbach’s α for the PLESI was 0.77 . The distribution of the PLESI was consistent with a normal distribution, with a mean value of 52.7 and standard deviation of 19.4. It had a coefficient of rep eatability of 20.1. The PLESI was positively correlated with EOPSSR (rs = 0.69, P=0.039) and the number of years since onset of PLE (rs=0.25, P=0.03). There was no association between the PLESI and the duration of persistence of the eruptio n after ceasing sun exposure (rs=0.12, P= 0.30), the development of tolerance as summer progressed (rs=- 0.14, P=0.39), gender (P=0.50) or skin type (P=0.87). conclusions: This study has (i) validated the concept that a single score can re flect disease severity in PLE by showing that the principal characteristics of t he condition, including, for example, the extent of anatomical distribution and the ea

关键词：多形性可重复性常态分布可靠性分析问卷调查 α值发病机制持续时间刺激物评分标准

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Spatial analysis of Dengue through the reproduction numbers relating to socioeconomic features:case studies on two brazilian urban centers

引用

Infectious Disease Modelling 2024年第1期9卷 142-157页

作者： Ana T.c.Silva Rejane c.Dorn Lívia R.Tomás Leonardo b.L.Santos Lacita M.Skalinski Suani T.R.Pinho Departamento de Física Universidade Estadual de Feira de SantanaAv.Transnordestinas/n.Novo HorizonteFeira de Santana44036-900BABrazil Instituto de Física Universidade Federal da BahiaRua Barão de Jeremoabo s/nCampus Universitário de OndinaSalvador40170-115BABrazil centro Nacional de Monitoramento e Alertas de Desastres Naturais(cEMADEN) Estrada Dr.Altino Bondensan500São Josédos Campos12247-016SPBrazil Universidade Estadual de Santa cruz Campus Soane Nazaréde AndradeRodovia Jorge AmadoKm 16SalobrinhoIlhéus45662-900BABrazil Instituto de Saúde coletiva Universidade Federal da BahiaR.Basílio da Gamas/n-CanelaSalvador40110-140BABrazil Instituto Nacional de ciência e Tecnologia-Sistemas complexos Virtual InstitutionBrazil

The study of the propagation of infectious diseases in urban centers finds a close connection with their population's social characteristics and *** work performs a spatial analysis of dengue cases in urban centers based on the basic reproduction numbers,R0,and incidence by planning areas(pas),as well as their correlations with the Human Development Index(HDI)and the number of *** analyzed dengue epidemics in 2002 at two brazilian urban centers,belo Horizonte(bH)and Rio de Janeiro(RJ),using pas as spatial *** results reveal heterogeneous spatial scenarios for both cities,with very weak correlations between R0 and both the number of trips and the HDI;in bH,the values of R0 show a less spatial heterogeneous pattern than in *** bH,there are moderate correlations between incidence and both the number of trips and the HDI;meanwhile,they weakly correlate for ***,the absence of strong correlations between the considered measures indicates that the transmission process should be treated considering the city as a whole.

关键词： Dengue Mathematical mode lbasic reproduction number Urban mobility Urban indices

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

比较全身MRI(Wb-MRI)与中轴骨MRI(AS-MRI)对前列腺癌(Pca)骨转移瘤的检出与计量

引用

国际医学放射学杂志 2011年第1期34卷 101-102页

作者： F.E.Lecouvet M.Simon b.Tombal J.Jamart b.c.vande berg P.Simoni 许亮 Department of Radiology and Medical Imaging Université Catholique de LouvainCliniques Universitaires St Luc

目的比较全身MRI(Wb-MRI)和中轴骨MRI(AS-MRI)对前列腺癌(Pca)骨转移瘤的检出与计量。方法对60例存在转移瘤高风险的Pca病人行Wb-MRI和AS-

关键词：前列腺癌骨 MRI 转移瘤

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

cT关节造影和1.5 T MR关节造影对盂肱关节软骨评估的诊断性能:与关节镜的对比研究

引用

国际医学放射学杂志 2015年第3期 297-298页

作者： P.Omoumi A.Rubini J.E.Dubuc.b.c.vande berg F.E.Lecouvet 娄飞飞 Department of Radiology Lausanne University HospitalBugnon46 1011 Lausanne Switzerland

目的比较多层螺旋cT关节造影(cTA)和1.5 TMR关节造影(MRA)在检测肩关节透明软骨损伤的诊断性能,并与关节镜进行对比研究。材料与方法对连续56例病

关键词：盂肱关节软骨损伤关节造影 cT 诊断性能关节镜对比研究

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

评价肩袖肌腱撕裂:多层螺旋cT关节成像与1.5TMR关节成像的比较

引用

国际医学放射学杂志 2012年第6期 580-581页

作者： P.Omoumi A.c.b.fort J.E.Dubuc J.Malghem b.c.vande berg F.E.Lecouvet 胡丽丽郭琪 Department of Radiology SaintLuc University HospitalUC LouvainHippocrate Avenue 10/2942B-1200 BrusselsBelgium

摘要目的比较多层螺旋cT关节成像与1.5T MR关节成像对于肩袖损伤的诊断价值。材料与方法本研究已获得伦理委员会批准,且所有受试者均签署知情同意书。对56例病人分别行cT及MR关节成像,并由2名放射科医师独立评估

关键词：关节 MR 敏感度运动器官肩袖损伤肩袖肌腱肱二头肌腱肩胛下肌 cT

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

双股寡聚d(G-c)_6 DNA Z-构象的形成及其构象转换的动态研究(英文)

引用

激光生物学报 2005年第5期14卷 359-367页

作者：黄汝多李振华 vande Sand J.H. 中国安徽大学生命科学学院中国安徽合肥230039 加拿大卡尔加里大学医药和医学生化系健康研究中心

研究揭示,生物信息的形成,传递与DNA构象的多样性,特别是其中的左手螺旋Z-构象DNA(Z-DNA)相关。在机体DNA链中,普遍存在的特异序列结构d(c-G)n和d(G-c)n片段易形成Z-构象。但对d(G-c)n序列结构的寡聚体Oligo-d(G-c)n,(n小于8)能转换形成... 详细信息

研究揭示,生物信息的形成,传递与DNA构象的多样性,特别是其中的左手螺旋Z-构象DNA(Z-DNA)相关。在机体DNA链中,普遍存在的特异序列结构d(c-G)n和d(G-c)n片段易形成Z-构象。但对d(G-c)n序列结构的寡聚体Oligo-d(G-c)n,(n小于8)能转换形成Z-DNA片段少见报道。为促进对Z-DNA尤其是其中的短片段Z-DNA与生物功能的相关性研究,我们对合成并纯化后的寡聚体Oligo-d(G-c)n,n分别为4,6,8,10,及Oligo-d(c-G)6和多聚体poly-d(G-c)500-900进行Z-构象的形成和其构象转换的比较研究。研究结果发现:①d(GpcpGpcpGpcpG-pcpGpcpGpc)是d(G-c)n序列结构中能转换形成Z-构象的最短片段(n=6)。其转换成Z-构象能力有链长依赖性(poly d(G-c)500-900易于Oligo-d(G-c)6);②Oligo-d(G-c)6的Z-构象形成能力因溶液中的介质性质不同而异。co(NH3)3+>Mg2+>Na+;c1O4->cl-,因此要求盐溶液的浓度差异很大。③PH7.2,室温条件下,在Mgcl2,NaclO4,Nacl溶液浓度分别由0 mol/L增至6.0 mol/L,Oligo-d(G-c)6的b、Z构象转换都出现:b-构象相对稳定期,b-、Z-构象转换跃迁期和Z-构象相对稳定期。每个阶段要求跨越的盐浓度变迁范围也因所用介质而异。当溶液中Oligo-d(G-c)6b-构象、Z-构象各占50%(θ1/2)时,其盐浓度分别为1.72 mol/L(Mgcl2),2.88 mol/L(NaclO4),3.85 mol/L(Nacl)。④Oligo-d(G-c)6的b-,Z-构象转换程度受盐浓度影响:当Oligo-d(G-c)6处于最适条件和不同盐溶液其浓度为θ21浓度时,温度由8℃→22℃,在Mgcl2,NaclO4溶液中的Oligo-d(G-c)6形成Z-构象能力增加,当由22℃→60℃,Mgcl2溶液中的Z-构象Oligo-d(G-c)6加速增加,而在NaclO4溶液中则是急速向b-型Oligo-d(G-c)6方向转换;温度变化对处于Nacl溶液中的Oligo-d(G-c)6b-、Z-构象相对平衡影响较小。⑤甲基化胞嘧啶即Oligo-d(G-mc)6或d(mc-G)6均增大Z-构象形成能力。⑥在4 mol/L Mgcl2溶液中的Oligo-d(G-c)6或Oligo-d(c-G)6或poly d(G-c)500-900的UVab谱、UVcd谱均显示出非b-型或Z-型DNA的新谱型。并且有链长依赖性和因溶液浓度改变出现构象可逆性转变。提示在Oligo-d(G-c)6的构象转换过程中可能存在新构象“X”型,即b Z X构象转换模式。

关键词：右手螺旋b-型DNA 左手螺旋Z-型DNA b-Z构象转换紫外吸收光谱紫外园二色性光谱 DNA新构象"X"

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

characterization of thixoforming process of 100cr6 steel

引用

中国有色金属学会会刊：英文版 2010年第S3期20卷 916-920页

作者： K.P.SOLEK A.RASSILI J.c.PIERRET G.VANEETVELD AGH University of Science and Technology av.Mickiewicza 3030-059 KrakówPoland Thixo-Unit ULg PiMW(B56)University of L iègeBd de Colonster 4B-4000 LiègeBelgium

The main goal of this work is to analyze the semi-industrial process of steel *** process was carried out using industrial *** equipment consists of a heating device,industrial robots and a hydraulic *** globular microstructure ensuring thixotropic properties was obtained using the SIMA *** is one of the simplest and cheapest methods which could be easy applied in the case of steel *** this work,the hot forged rods,commercially produced from 100cr6 steel,were *** first part of the work concerned the determination of the proper temperature range,for thixoforming of 100cr6 ***,some heating tests were carried out in order to obtain as uniform temperature distribution as *** process was executed using inductive *** analysis of heated samples reveals globular particles surrounded by liquid *** last,the thixoforming process was carried out using closed-die forming *** filled die cavity and good microstructure of the part show that applied process parameters were properly selected.

关键词： thixoforming globular microstructure rheological properties physical modeling numerical modeling

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Effect of dietary supplementation with yeast cell wall extracts on performance and gut response in broiler chickens

引用

Journal of Animal Science and biotechnology 2020年第3期11卷 736-746页

作者： A.pascual M.Pauletto M.Giantin G.Radaelli c.b.llarin M.birolo c.Zomeño M.Dacasto M.bortoletti M.Vascellari G.Xiccato A.Trocino Department of comparative biomedicine and Food Science(bcA) University of PadovaViale dell’Università16I-35020 LegnaroPadovaItaly department of agronomy foodnatural resourcesanimaland environment(dafnae)university of padovaviale dell’università16i-35020 legnaropadovaitaly histopathology department istituto zooprofilattico sperimentale delle venezieviale dell’università10i-35020 legnaropadovaitaly

background:The dietary supplementation of yeast cell wall extracts(YcW)has been found to reduce pathogenic.b.cteria load,promote immunoglobulin production,prevent diseases by pro-inflammatory responses,and alter gut microbiota *** study evaluated growth and slaughter results,health,gut morphology,immune status and gut transcriptome of 576 male chickens fed two diets,i.e.c(control)or Y(with 250–500 g/t of YcW fractions according to the growth period).At 21 and 42 d the jejunum of 12 chickens per diet were sampled and stained with hematoxylin/eosin for morphometric evaluation,with Alcian-pas for goblet cells,and antibodies against cD3+intraepithelial T-cells and cD45+intraepithelial *** jejunum sampled at 42 d were also used for wholetranscriptome ***:Dietary YcW supplementation did not affect final live weight,whereas it decreased feed intake(114 to 111 g/d;P≤0.10)and improved feed conversion(1.74 to 1.70;P≤0.01).Regarding the gut,YcW supplementation tended to increase villi height(P=0.07);it also increased the number of goblet cells and reduced the density of cD45+cells compared to diet c(Pcriptome,four genes were expressed more in broilers fed diet Y compared to diet c,*** P450,family 2,subfamily c,polypeptide 23b(cYP2c23b),tetratricopeptide repeat domain 9(TTc9),basic helix-loop-helix family member e41(bHLHE41),and the metalloreductase *** one gene set(HES_PATHWAY)was significantly enriched among the transcripts more expressed in broilers fed diet ***,a total of 41 gene sets were significantly over-represented among genes up-regulated in control ***,several enriched gene sets are implicated in immune functions and related to NF-κb signaling,apoptosis,and interferon ***:The dietary YcW supplementation improved broiler growth performance,increased gut glycoconjugate secretion and reduced the inflammatory status together with differences in the gut tran

关键词： Gut morphometry Immuno-histochemistry Saccharomyces cerevisiae Transcriptomic analysis

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

The basic Helix-Loop-Helix Transcription Factor MYc1 Is Involved in the Regulation of the Flavonoid biosynthesis Pathway in Grapevine

引用

Molecular Plant 2010年第3期3卷 509-523页

作者： Imene Hichri Simon c. Heppel Jeremy Pillet celine Leon Stefan czemmel Serge Delrot Virginie Lauvergeat Jochen bogs Institut des Sciences de la Vigne et du Vin UMR 1287 Ecophysiologie et G~nomique Fonctionnelle de la Vigne~lNRA Universit~ de Bordeaux 210 Chernin deLeysotte 33882 Villenave d'Ornon France Heideiberger Institut for Pflanzenwissenschaften im Neuenheimer Feld 360 69120 Heidelberg Germany

Previous results indicated that in grapevine （Vitis vinifera）, regulation of the flavonoid pathway genes by MYb transcription factors depends on their interaction with basic helix-loop-helix proteins （bHLHs）. The present study describes the first functional characterization of a bHLH factor from grapevine named VvMYc1. This transcription factor is phylogenetically related to Arabidopsis bHLH proteins, which participate in the control of flavonoid biosynthesis and epidermal cell fate. Transient promoter and yeast two-hybrid assays demonstrated that VvMYc1 physically interacts with MYb5a, MYb5b, MYbA1/A2, and MYbPA1 to induce promoters of flavonoid pathway genes involved in anthocyanin and/ or proanthocyanidin （PA） synthesis. Additionally, transient promoter assays revealed that VvMYc1 is involved in feedback regulation of its own expression. Transcript levels of VvMYc1 during berry development correlate with the synthesis of anthocyanins and pas in skins and seeds of berries, suggesting that VvMYc1 is involved in the regulation of anthocyanins and PA synthesis in these organs. Likewise, transient expression of VvMYc1 and VvMYbA1 induces anthocyanin synthesis in grapevine suspension cells. These results suggest that VvMYcl is part of the transcriptional cascade controlling antho- cyanin and PA biosynthesis in grapevine.

关键词： Fruit ripening molecular physiology secondary metabolismmphenylpropanoids and phenolics gene regu-lation transcriptional control and transcription factors grapevine.

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

High Nitrogen Pressure Solution (HNPS) growth of GaN on 2 inch free standing GaN substrates

引用

Science china(Technological Sciences) 2011年第1期54卷 42-46页

作者： M.bOKOWSKI I.GRZEGORY b.LUcZNIK T.SOcHAcKI M.KRYKO G.KAMLER S.POROWSKI Institute of High Pressure Physics pas

Recent results of High Nitrogen Pressure Solution (HNPS) growth of GaN crystals deposited on and separated from 2 inch,and smaller,GaN substrates grown by Hydride Vapor Phase Epitaxy (HVPE) have been presented. The influence of the c-plane bowing in the initial substrate on quality,rate and mode of growth by HNPS method has been analyzed in details.

关键词： High Nitrogen Pressure Solution (HNPS) growth seeded growth Hydride Vapor Phase Epitaxy (HVPE) growth

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：