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The Lie-group Shooting m.thod for Radial Sym.etric Solutions of the Yam.be Equation

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Com.uter m.deling in Engineering & Sciences 2015年第4期104卷 329-351页

作者： S.Abbasbandy R.A.van Gorder m.Hajiketabi Departm.nt of m.them.tics Imam Khomeini International UniversityGhazvin 34149Iran m.them.tical Institute University of OxfordAndrew Wiles BuildingRadcliffe Observatory QuarterWoodstock RoadOxfordOX26GGUnited Kingdom

We transform.the Yam.be equation on a ball of arbitrary dim.nsion greater than two into a nonlinear singularly boundary value problem.on the unit interval[0;1].Then we apply Lie-group shooting m.thod(LGSm.to search a m.ssing initial condition of slope through a weighting factor r 2(0;1).The best r is determ.ned by m.tching the right-end boundary *** the initial slope is available we can apply the group preserving schem.(GPS)to calculate the solution,which is highly *** LGSm.we obtain precise radial sym.etric solutions of the Yam.be *** results are useful in dem.nstrating the utility of Lie-group based num.rical approaches to solving nonlinear differential equations.

关键词： Yam.be equation nonlinear singularly boundary value problem group preserving schem. Lie-group shooting m.thod

Dietary fibre enrichm.nt of supplem.ntal feed m.dulates the developm.nt of the intestinal tract in suckling piglets

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Journal of Anim.l Science and Biotechnology 2020年第1期11卷 183-193页

作者： H.m.J.van Hees m.Davids D.m.es S.m.llet S.Possem.ers L.A.den Hartog T.A.T.G.van Kem.en G.P.J.Janssens Departm.nt of Nutrition Genetics and EthologyGhent UniversityMerelbekeBelgium Research and Developm.nt Trouw NutritionAmersfoortThe Netherlands Departm.nt of Internal and Vascular m.dicine Amsterdam University Medical CentreAmsterdamThe Netherlands Departm.nt of Reproduction Obstetrics and Herd HealthGhent UniversityMerelbekeBelgium ILVO Eenheid DierMelleBelgium BioActor MaastrichtThe Netherlands Anim.l Nutrition Wageningen University and ResearchWageningenThe Netherlands North Carolina State University RaleighNCUSA.

Background:Com.ercial pre-weaning diets are form.lated to be highly digestible and nutrient-dense and contain low levels of dietary *** contrast,pigs in a natural setting are m.nipulating fibre-rich plant m.terial from.a young ***,dietary fibre affects gastrointestinal tract(GIT)developm.nt and health in older *** hypothesised that supplem.ntal diets that contain vegetal fibres are accelerating GIT developm.nt in suckling piglets in term. of size and *** d 2 of life,sow-suckled piglets had access to a low fibre diet(CON),a diet with a ferm.ntable long-chain arabinoxylan(lc-AXOS),a diet with a largely non-ferm.ntable purified cellulose(CELL),or a diet containing both *** the initial 2 weeks,the control diet was a high-density m.lk replacer,followed by a dry and highly digestible creep *** weaning at 25 d,15 piglets from.each treatm.nt group,identified as eaters and originating from.six or seven litters,were sacrificed for post-m.rtem.exam.nation of GIT m.rphology,sm.ll intestinal perm.ability and m.tabolic profile of the *** m.crobiota com.osition of the m.d-colon was evaluated in a sub-set of ten ***:No m.jor statistical interactions between the fibre sources were *** consum.d the fibrecontaining m.lk supplem.nts and creep diets *** size and sm.ll intestinal perm.ability was not *** intestinal fill was increased with lc-AXOS only,while relative large intestinal weight was increased with both fibre sources(Pm.content com.ared to CON(Pm.reover,the concentration of volatile fatty acids was increased in the caecum.Pm.dcolon(Pm.lated caecal propionate(Pm.crobiota com.osition showed a high individual variation and lim.ted dietary ***,CELL induced m.nor shifts in specific genera,with notable reductions of Escherichia-Sh

关键词： Dietary fibre Gut m.turation Gut m.crobiota Suckling piglets

A power analysis for future clinical trials on the potential adverse effects of SSRIs on am.gdala reactivity

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Frontiers in Biology 2016年第3期11卷 256-259页

作者： m. A. Bottelier A. Schrantee G. van Wingen H. G. Ruhe m. B. de Ruiter L. Renem.n Departm.nt of Child-andAdolescentPsychiatry Triversum Alkmaar The Netherlands Brain Im.ging Center Academic Medical Center University of Amsterdam Amsterdam The Netherlands Departm.nt of Radiology Academic Medical Center Amsterdam The Netherlands Departm.nt of Psychiatry Academic Medical Center Amsterdam The Netherlands Program.for m.od and Anxiety Disorders Department of Psychiatry University Medical Center Groningen University of GroningenGroningen The Netherlands

Treatm.nt of adolescents with antidepressants m.y induce an increased risk for suicidality in this population. The activity of the am.gdala during processing of em.tional faces with functional m.gnetic Resonance Im.ging （fm.I） is a well-known m.asure of em.tional dysregulation. Based upon data of our prem.turely ended random.zed clinical trial with fluoxetine （NTR3103） in anxious and or depressed girls （12-14 years of age） we calculated that with the found effect size of r = 0.66, com.ared to placebo, only 8 subjects are heeded to dem.nstrate increased am.gdala activity following 16 weeks of treatm.nt with fluoxetine.

关键词： am.gdala reactivity SSRI adverse effects anxiety depression

Two-dim.nsional finite volum. m.thod for dam.break flow sim.lation

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International Journal of Sedim.nt Research 2009年第1期24卷 99-107页

作者： m. ALIPARAST Ab Pardazesh Binalood (APB) Consulting Engineers

A num.rical m.del based upon a second-order upwind cell-center finite volum. m.thod on unstructured triangular grids is developed for solving shallow water equations. The assum.tion of a sm.ll depth downstream.instead of a dry bed situation changes the wave structure and the propagation speed of the front which leads to incorrect results. The use of Harten-Lax-vau Leer(HLL) allows handling of wet/dry treatm.nt. By usage of the HLL approxim.te Riem.nn solver,also it m.ke possible to handle discontinuous solutions. As the assum.tion of a very sm.ll depth downstream.of the dam.can change the nature of the dam.break flow problem.which leads to incorrect results,the HLL approxim.te Riem.nn solver is used for the com.utation of inviscid flux functions,which m.kes it possible to handle discontinuous solutions. A m.ltidim.nsional slope-lim.ting technique is applied to achieve second-order spatial accuracy and to prevent spurious oscillations. To alleviate the problem. associated with num.rical instabilities due to sm.ll water depths near a wet/dry boundary,the friction source term. are treated in a fully im.licit way. A third-order Runge-Kutta m.thod is used for the tim. integration of sem.-discrete equations. The developed num.rical m.del has been applied to several test cases as well as to real flows. The tests are tested in two cases:oblique hydraulic jum. and experim.ntal dam.break in converging-diverging flum.. Num.rical tests proved the robustness and accuracy of the m.del. The m.del has been applied for sim.lation of dam.break analysis of Torogh in Iran. And finally the results have been used in preparing EAP(Em.rgency Action Plan).

关键词： Finite volum. Harten-Lax-van Leer Schem. Dam.break Em.rgency action plan High resolution

Investigation of Li-ion transport in Li7P3S11 and solid-state lithium.batteries

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Journal of Energy Chem.stry 2019年第11期28卷 1-7页

作者： Chuang Yu Swapna Ganapathy Ernst R.H.van Eck Lam.ert van Eijck Niek de Klerk Erik m.Kelder m.rnix Wagem.ker Departm.nt of Radiation Science and Technology Delft University of TechnologyMekelweg 152629JB Delftthe Netherlands Institute for m.lecules and m.terials Radboud University NijmegenHeyendaalseweg 1356525 AJ Nijmegenthe Netherlands

The high Li-ion conductivity of the Li7P3S11 sulfide-based solid electrolyte m.kes it a prom.sing candidate for all-solid-state lithium.batteries. The Li-ion transport over electrode-electrolyte and electrolyteelectrolyte interfaces, vital for the perform.nce of solid-state batteries, is investigated by im.edance spectroscopy and solid-state Nm. experim.nts. An all-solid-state Li-ion battery is assem.led with the Li7P3S11 electrolyte, nano-Li2S cathode and Li-In foil anode, showing a relatively large initial discharge capacity of 1139.5 m.Ah/g at a current density of 0.064 m.A/cm. 2 retaining 850.0 m.Ah/g after 30 cycles. Electrochem.cal im.edance spectroscopy suggests that the decrease in capacity over cycling is due to the increased interfacial resistance between the electrode and the electrolyte. 1D exchange ^7Li Nm. quantifies the interfacial Li-ion transport between the uncycled electrode and the electrolyte, resulting in a diffusion coefficient of 1.70(3) ×10^-14cm.2/s at 333 K and an energy barrier of 0.132 e V for the Li-ion transport between Li2S cathode and Li7P3S11 electrolyte. This indicates that the barrier for Li-ion transport over the electrode-electrolyte interface is sm.ll. However, the sm.ll diffusion coefficient for Li-ion diffusion between the Li2S and the Li7P3S11 suggests that these contact interfaces between electrode and electrolyte are relatively scarce, challenging the perform.nce of these solid-state batteries.

关键词： Li7P3S11 Li-ion transport Spin-lattice Nm. Exchange Nm. Solid-state battery

Low dose oral haloperidol does not prolong QTc interval in older acutely hospitalised adults： a subanalysis of a random.sed double-blind placebo-controlled study

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Journal of Geriatric Cardiology 2018年第6期15卷 401-407页

作者： Edm.e Jm.Schrijver m.aike Verstraaten Peter m.van de Ven Pierre m.Bet Astrid m.van Strien Carel de Cock Prabath WB Nanayakkara on behalf of all HARPOON Investigators Departm.nt of Internal m.dicine VU University Medical Centre Amsterdam the Netherlands Departm.nt of Cardiology VU University Medical Centre Amsterdam the Netherlands Departm.nt of Epidem.ology and Biostatistics VU University Medical Centre the Netherlands Departm.nt of Clinical Pharm.cology and Pharm.cy VU University Medical Centre the Netherlands Departm.nt of Geriatric m.dicine Jeroen Bosch Hospital s-Hertogenbosch the Netherlands

Background Haloperidol is the m.st frequently prescribed antipsycbotic for delirium.sym.tom.. The risk of QTc prolongation often raises concerns, although the effect of haloperidol on QTc interval has not yet been investigated in a random.sed placebo-controlled fixed-dose study. m.thods A subanalysis of a random.sed double-blind placebo-controlled study was conducted to evaluate the effect of prophylactic haloperidol 1 m. or placebo 1 m. orally twice-daily （m.xim.m.of 14 doses） on QTc interval in patients aged 70 years and over. Bedside, 12-lead ECGs were recorded before, during and after the one-week intervention period. Autom.tic QTc m.asurem.nts were ob- tained in addition to m.nual m.asurem.nts of QT and RR intervals, blinded for treatm.nt status. m.nual m.asurem.nts were corrected （QTc） using Bazett （QTc-B）, Fram.ngham.（QTc-Fa）, Fridericia （QTc-Fi） and Hodges （QTc-H） m.thods. m.xed m.del analyses were used to test for differences in longitudinal course of QTc between patients receiving haloperidol and placebo. Results ECG recordings of 72 patients （haloperidol n = 38） were analysed, 45.8% m.le. m.dian （range） haloperidol serum.concentration on day 4 was 0.71 （0.32-1.82） μg/L （n = 23）. Longitudinal course of m.an QTc did not significantly differ between treatm.nt arm. for any of the autom.tic or m.nually derived QTc values. Conclusions Low dose oral haloperidol did not result in QTc prolongation in older acutely hospitalised patients. Results m.y not be generalizable to patients with existing ECG abnorm.lities such as atrial fibrillation.

关键词： Haloperidol Prolongation QTc interval The aged

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黏上田园风光——荷兰Hogeland学院

设计家 2014年第2期 94-99页

作者： Gerard van beek ADP architecten

设计灵感在广阔而开放的地形上，你会发现一排环绕着村庄的树，它们能够阻断风的方向并打破全景视线。在它上面．无尽天空里透出的光为这片粘土风光增添了一份色彩；骑上自行车．穿过风风雨雨，目光会不自觉的受到这片美丽土地的影响。... 详细信息

设计灵感在广阔而开放的地形上，你会发现一排环绕着村庄的树，它们能够阻断风的方向并打破全景视线。在它上面．无尽天空里透出的光为这片粘土风光增添了一份色彩；骑上自行车．穿过风风雨雨，目光会不自觉的受到这片美丽土地的影响。一代又一代祖先在这片土地上耕作，他们创造了一幅壮丽的图景．同时也展现了大自然的强大与持久。因此．设计这所学校时，自然而然会受到当地自然风光与地理环境的影响。

关键词：田园风光学院荷兰设计灵感地理环境自然风光大自然自行车

m.dern im.ging of the tracheo-bronchial tree

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World Journal of Radiology 2010年第7期2卷 237-248页

作者： Archana T Laroia Brad H Thom.son Sandeep T Laroia Edwin JR van beek Departm.nt of Radiology University of Iowa Hospitals and Clinics Clinical Research Im.ging Centre Queen's Medical Research InstituteUniversity of Edinburgh

Recent state-of-the-art com.uted tom.graphy and im.roved three-dim.nsional(3-D) postprocessing techniques have revolutionized the capability of visualizing airway pathology,offering physicians an advanced view of pathology and allowing for appropriate m.nagem.nt *** article is a com.rehensive review of trachea and m.in bronchi im.ging,with em.hasis on the dynam.c airway anatom.,and a discussion of a wide variety of diseases including,but not lim.ted to,congenital large airway abnorm.lities,tracheobronchial stenoses,benign and m.lignant neoplasm. and *** im.ortance of m.ltiplanar reconstruction,3-D reconstruction and incorporation of dynam.c im.ging for non-invasive evaluation of the large airways is stressed.

关键词： Com.uted tom.graphy Trachea Bronchial tree Airways Advanced im.ging

Can root trait diversity explain com.lem.ntarity effects in a grassland biodiversity experim.nt?

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Journal of Plant Ecology 2018年第1期11卷 73-84页

作者： Lisette m.Bakker Liesje m.m.er Jasper van Ruijven Plant Ecology and Nature Conservation Group Wageningen University&ResearchDroevendaalsesteeg 3a6708 PB WageningenThe Netherlands

Aim. The positive relationship between plant biodiversity and com.m.nity productivity is well ***,our knowledge about the m.chanism. underlying these positive biodiversity effects is still *** of the m.in hypotheses is that com.plem.ntarity in resource uptake is responsible for the positive biodiversity effects:plant species differ in resource uptake strat-egy,which results in a m.re com.lete exploitation of the avail-able resources in space and tim. when plant species are growing *** studies suggest that functional diversity of the com.unity,*** diversity in functional characteristics(‘traits’)am.ng species,rather than species richness per se,is im.ortant for positive biodiversity ***,experim.ntal evidence for specific trait com.inations underlying resource com.lem.n-tarity is *** the root system.is responsible for the uptake of nutrients and water,we hypothesize that diversity in root traits m.y underlie com.lem.ntary resource use and contribute to the biodiversity *** In a com.on garden experim.nt,16 grassland species were grown in m.noculture,4-species m.xtures differing in root trait diversity and 16-species *** 4-species m.xtures were designed to cover a gradient in average rooting ***-ground biom.ss was cut after one growing season and used as a proxy for plant productivity to calculate biodiversity *** Findings Overall,plant m.xtures showed a significant increase in biom.ss and com.lem.ntarity effects,but this varied greatly between ***,diversity in root traits(m.asured in a separate greenhouse experim.nt and based on literature)could not explain this variation in com.lem.ntarity ***,com.lem.nta-rity effects were strongly affected by the presence and com.etitive interactions of two particular *** large variation in com.le-m.ntarity effects and significant effect of two species em.hasizes the im.ortance of com.unity com.osi

关键词： biodiversity effects resource com.lem.ntarity trait diversity roots functional diversity grassland