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Repeatability of Pre-Harvest Sprouting in Wheat

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American Journal of Plant Sciences 2014年第11期5卷 1607-1613页

作者： Eduardo Stefani Pagliosa valeria carpentieri-pipolo Deoclécio Domingos Garbuglio Thiago Henrique Oro Karla Bianca de Almeida Lopes Claudemir Zucareli Agricultural Research Institute of Paraná State—IAPAR Londrina Brazil State University of Londrina Londrina Brazil

This study aimed to detect genotypic differences in the resistance to sprouting of wheat grains, evaluate the effectiveness of different methods for inducing sprouting and identify, using repeatability estimates, the minimum number of spikes necessary for the adequate evaluation of the percentage of grain sprouting in the spike in order to assist in the selection of superior genotypes in breeding programs. Spikes from four wheat cultivars (Frontana, IPR Catuara, Quartzo and BRS 220) were evaluated using three methods for inducing grain sprouting in the spike (water immersion, rainfall simulation and germination chamber). To determine the most efficient method, repeatability coefficients were estimated through analysis of variance, principal components analysis and structural analysis based on correlation and covariance matrices. The induction of sprouting by immersion in water was the most effective method for indicating genotypic differences and may be used in breeding programs for this purpose. The repeatability method based on the components of covariance was more efficient. A minimum of 11 spikes is required to make a high-reliability estimate of the percentage of sprouted grains in the spike.

关键词： Triticum aestivum Rainfall Simulator Repeatability

The interplay of drug therapeutics and immune responses to SARS-CoV-2

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Cellular & Molecular Immunology 2024年第2期21卷 197-200页

作者： valeria Fumagalli Matteo Iannacone Division of Immunology Transplantationand Infectious DiseasesIRCCS San Raffaele Scientific InstituteMilanItaly Vita-Salute San Raffaele University MilanItaly Experimental Imaging Centre IRCCS San Raffaele Scientific InstituteMilanItaly

The SARS-CoV-2 pandemic has necessitated rapid therapeutic and preventative *** vaccines form the frontline of defense,antiviral treatments such as nirmatrelvir have emerged as vital adjunctive measures,particularly for those unable or unwilling to be *** review delves into the potential influence of nirmatrelvir on enduring *** parallel,the potential of drug repurposing is explored,with bisphosphonates being examined for their possible effects against COVID-19 due to their immunomodulatory *** importance of rigorous clinical trials and careful interpretation of preliminary data is emphasized.

关键词： SARS-CoV-2 Nirmatrelvir Bisphosphonates Adaptive immunity Drug repurposing

Expanding through the Emerald Isle:exploration and spatial orientation of non-native bank voles in Ireland

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Current Zoology 2024年第3期70卷 320-331页

作者： valeria Mazza Jana A.Eccard Animal Ecology Institute for Biochemistry and BiologyUniversity of PotsdamMaulbeerallee 114469PotsdamGermany and Department of Ecological and Biological Sciences University of TusciaLargo dell'Università10100 ViterboItaly

Whether introduced into a completely novel habitat or slowly expanding their current range,the degree to which animals can effciently explore and navigate new environments can be key to survival,ultimately determining population establishment and colonization *** tested whether spatial orientation and exploratory behavior are associated with non-native spread in free-living bank voles(Myodes glareolus,N=43)from a population accidentally introduced to Ireland a century *** measured spatial orientation and navigation in a radial arm maze,and behaviors associated to exploratory tendencies and risk-taking in repeated open-feld tests,at the expansion edge and in the source *** voles at the expansion edge re-visited unrewarded arms of the maze more,waited longer before leaving it,took longer to start exploring both the radial arm maze and the open feld,and were more risk-averse compared to conspecifcs in the source *** together,results suggest that for this small mammal under heavy predation pressure,a careful and thorough exploration strategy might be favored when expanding into novel environments.

关键词： animal personality biological invasions exploration behavior Myodes glareolus range expansion spatial orientation.

Behavioral flexibility and novel environments:integrating currentpers pectives for future directions

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Current Zoology 2024年第3期70卷 304-309页

作者： valeria Mazza Vedrana Šlipogor Department of Ecological and Biological Sciences University of TusciaLargo dell'Università101100 ViterboItaly Ichthyogenic Experimental Marine Centre(CISMAR) LocalitàLe Saline snc01016 TarquiniaItaly Department of Zoology University of South BohemiaBranišovská176037005ČeskéBudějoviceCzech Republic Department of Ecology and Evolution University of LausanneQuartier UNIL-SorgeBâtiment BiophoreCH-1015 LausanneSwitzerland The Sense–Innovation and Research Center Lausanne&Sion Avenue de Provence 821007 LausanneSwitzerland

Individuals in the process of encountering a novel environment face several new selective pressures that can lead to changes in phenotypes,which provides an exciting opportunity to study microevolutionary *** novelty encompasses a variety of changes in the socioecological world of an individual,as well as situations for which animals lack eco-evolutionary experience(e.g.,Saul et al.2013;Heger et al.2019).

关键词： environments evolutionary processes

Why is early detection of colon cancer still not possible in 2023?

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World Journal of Gastroenterology 2024年第3期30卷 211-224页

作者： valeria Tonini Manuel Zanni Department of Medical and Surgical Sciences University of BolognaBologna 40138Italy

Colorectal cancer(CRC)screening is a fundamental tool in the prevention and early detection of one of the most prevalent and lethal *** the years,screening,particularly in those settings where it is well organized,has succeeded in reducing the incidence of colon and rectal cancer and improving the prognosis related to *** considerable advancements in screening technologies and strategies,the effectiveness of CRC screening programs remains less than *** paper examined the multifaceted reasons behind the persistent lack of effect-iveness in CRC screening *** a critical analysis of current methodologies,technological limitations,patient-related factors,and systemic challenges,we elucidated the complex interplay that hampers the successful reduction of CRC morbidity and mortality *** acknowledging the ad-vancements that have improved aspects of screening,we emphasized the necessity of addressing the identified barriers *** study aimed to raise awareness of how important CRC screening is in reducing costs for this *** and early diagnosis are not only important in improving the prognosis of patients with CRC but can lead to an important reduction in the cost of treating a disease that is often diagnosed at an advanced *** more sooner can mean saving money later.

关键词： Colorectal cancer Colorectal cancer screening Colorectal screening test Colon and rectal cancer

Soybean Improvement for Lipoxygenase-free by Simple Sequence Repeat(SSR)Markers Selection

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Journal of Botanical Research 2021年第1期3卷 23-31页

作者： valeria carpentieri-pipolo Thales Pereira Barreto Daiana Alves da Silva Ricardo Vilela Abdelnoor Silvana Rockenbach Marin Giuliano Degrassi Embrapa Trigo P.O.Box 451Zip Code 99001-970 Passo FundoRio Grande do SulBrazil Syngenta Proteção de Cultivos LTDA.São Paulo SPBrazil Agronomic Institute(IAC)-Center for Grain and Fiber-Zip Code 13075-630-Campinas SPBrazil Embrapa Soja Zip Code 86001970LondrinaPRBrazil International Centre for Genetic Engineering and Biotechnology(ICGEB) Industrial Biotechnology GroupParque Tecnológico MigueleteSan MartínBuenos AiresRepública Argentina

Beany flavor of soybean(Glycine max(L.)Merr.)is caused by oxidation of polyunsaturated fatty acids by the action of three lipoxygenases(LOX1,LOX2 and LOX3)present in mature *** unpleasant flavor restricts human consumption of soybean *** problem could be solved through genetic elimination of alleles that code these *** cultivars and two hybrid population were selected and analyzed using genetic markers for alleles locus,encoding L_(ox1),L_(ox2)and L_(ox3)*** SSR marker Satt 212 confirmed the presence of the homozygous null-allele L_(x3)in the cultivar BRS 213,which were used for hybridization with BR *** F1 hybrid plants and homozygous L_(x3)lines in F_(2)segregating populations were successfully *** SSR markers Sat090 and Sat417 were the most effective diagnostic markers among all SSR markers ***090 and Satt417 confirmed the presence of the homozygous L_(x2)null-allele in the parental cultivar BRS 213 by flanking L_(x2)loci at 3,00 and 2,77 cM,*** presence of L_(x2)null allele in the F_(2)segregating populations between BRS 213 and BRS 155 was successfully identified with a selection efficiency of 98%and have great potential for further application in the Brazilian breeding program aimed at improving soybean seed quality.

关键词： Glycine max Lipoxygenase isozymes Molecular markers MAS

The relationship between morphology and flight in Drosophila:a study of two pairs of sibling species from a natural population

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Insect Science 2024年第3期31卷 885-900页

作者： Nicolás Flaibani Victoría Estefania Ortiz Juan JoséFanara valeria Paula Carreira Laboratorio de Evolucion Departamento de EcologiaGenética y Evolucion(DEGE)Facultad de Ciencias Exactas y Naturales(FCEN)Universidad de Buenos Aires(UBA)Instituto de GenéticaEcologia y Evolucion de Buenos Aires(IEGEBA)Consejo Nacional de Investigaciones Cientificasy Tecnicas(CONICET)-UBABuenos AiresArgentina

Insect flight is a complex trait involved in different behaviors,from the search for sexual partners,food,or breeding *** studies have postulated the adaptive advantages of certain morphological traits in relation to increased flight capacity,such as low values of wing loading or high values of wing:thorax ratio and wing-aspect ***,few studies have evaluated the relationship between variables related to flight and morphological traits in *** work aimed to study morphological traits in males and females of two pairs of sibling species:Drosophila buzzati Patterson and Wheeler-Drosophila koeferae Fontdevila and Wasserman,and Drosophila melanogaster Meigen-Drosophila simulans Sturtevant,and to analyze its relationship with *** detected the highest proportion of flight time in *** and *** compared to *** and ***,*** results also revealed sexual dimorphism,with males exhibiting a higher proportion of flight time than ***,we did not find a general pattern to explain the relationship between morphology and the proportion of flight time because associations varied depending upon the analyses(considering all groups together or each sex-species combination separately).Moreover,these associations explained a low percentage of variation,suggesting that other nonmorphological components related to flight,such as physiological variables,should be taken into *** work allowed us to show the variability and complexity of an aspect of flight,suggesting that the adaptive role of the morphological traits studied might have been overestimated.

关键词： morphological traits time in flight wing loading wing:thorax ratio wingaspect ratio wing second moment of area

How to identify early complications in patients undergoing distal gastrectomy?

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World Journal of Gastrointestinal Surgery 2024年第4期16卷 974-981页

作者： Giuseppe Tropeano Maria Michela Chiarello valeria Fico Giuseppe Brisinda Emergency Surgery and Trauma Center Fondazione Policlinico Universitario A Gemelli IRCCSRome 00168Italy Department of Surgery Azienda Sanitaria Provinciale di CosenzaCosenza 87100Italy Department of Medical and Surgical Sciences UniversitàCattolica del Sacro CuoreRome 00168Italy

In this editorial we comment on the article by Zhang et al published in a recent issue of the World Journal of Gastrointestinal *** with appropriate lymph node dissection is still standard curative treatment in locally advanced gastric *** studies point out that gastric cancer surgery is a complex procedure that leads to a high risk of morbidity and *** factors can contribute to the onset of complications with consequent effects on prognosis and increased *** complications can be divided in complications related to anastomosis,to motility and to surgical site *** study presented by Zhang B et al represent an interesting analysis on the possibility to prevent postoperative *** study was performed on 131 patients with distal gastric cancer who underwent gastrectomy with D2 lymph node *** these patients,16%developed early postoperative *** univariate analysis showed that prealbumin level,hypertension,diabetes,history of abdominal surgery,R0 resection,and blood transfusion were factors influencing early postoperative complications after distal ***,the inclusion of the above significant variables in the logistic regression analysis revealed that hypertension,diabetes,a history of abdominal surgery,and blood transfusion were independent predictors of postoperative *** conclusion,preoperative and intraoperative factors can be used to establish an early postoperative nomogram *** results of the study presented by Zhang et al suggest that the prediction model can be used to guide the detection of postoperative complications and has clinical reference value.

关键词： Gastric cancer Gastrectomy Lymph node dissection Morbidity Mortality Surgical site infections

Indocyanine green:The guide to safer and more effective surgery

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World Journal of Gastrointestinal Surgery 2024年第3期16卷 641-649页

作者： Pietro Fransvea Maria Michela Chiarello valeria Fico Maria Cariati Giuseppe Brisinda Emergency Surgery and Trauma Center Fondazione Policlinico Universitario Agostino Gemelli IRCCSRome 00168Italy Department of Surgery Azienda Sanitaria Provinciale di CosenzaCosenza 87100Italy Department of Surgery Azienda Sanitaria Provinciale di CrotoneCrotone 88900Italy Department of Abdominal and Endocrine Metabolic Medical and Surgical Sciences Fondazione Policlinico Universitario A Gemelli IRCCSRome 00168Italy

In this editorial we comment on the article by Kalayarasan and co-workers published in the recent issue of the World Journal of Gastrointestinal *** authors present an interesting review on the use of indocyanine green fluo-rescence in different aspects of abdominal *** also highlight future perspectives of the use of indocyanine green in mini-invasive ***-cyanine green,used for fluorescence imaging,has been approved by the Food and Drug Administration and is safe for use in *** can be administered in-travenously or *** its advent,there have been several advance-ments in the applications of indocyanine green,especially in the surgical field,such as intraoperative mapping and biopsy of sentinel lymph node,measurement of hepatic function prior to resection,in neurosurgical cases to detect vascular anomalies,in cardiovascular cases for patency and assessment of vascular ab-normalities,in predicting healing following amputations,in helping visualization of hepatobiliary anatomy and blood vessels,in reconstructive surgery,to assess flap viability and for the evaluation of tissue perfusion following major trauma and *** these reasons,the intraoperative use of indocyanine green has become common in a variety of surgical specialties and transplant ***-lorectal surgery has just lately begun to adopt this technique,particularly for perfusion visualization to prevent anastomotic *** regular use of in-docyanine green coupled with fluorescence angiography has recently been pro-posed as a feasible tool to help improve patient *** the best available data,it has been shown that routine use of indocyanine green in colorectal surgery reduces the rates of anastomotic *** use of indocyanine green is proven to be safe,feasible,and effective in both elective and emergency ***,additional robust evidence from larger-scale,high-quality studies is essential before incorporating indocyanine g

关键词： Indocyanine green Colorectal surgery Fluorescence-guided surgery Gastrointestinal surgery Hepato-biliary surgery Pancreatic surgery Surgical oncology