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Molecular dynamics of pre-germinative metabolism in primed eggplant(Solanum melongena L.)seeds

Horticulture Research 2020年第1期7卷 1599-1610页

作者： Chiara Forti valentino ottobrino Laura Bassolino Laura Toppino Giuseppe Leonardo Rotino Andrea Pagano Anca Macovei Alma Balestrazzi Department of Biology and Biotechnology‘Lazzaro Spallanzani’ University of PaviaPaviaItaly CREA-Research Centre for Genomics and Bioinformatics Montanaso LombardoLOItaly CREA-Research Centre for Cereal and Industrial Crops BolognaItaly Institute of Plant Genetics Polish Academy of SciencesPoznanPoland

Seed priming,a pre-sowing technique that enhances the antioxidant/DNA repair activities during the pre-germinative metabolism,still retains empirical *** explore for the first time the molecular dynamics of pre-germinative metabolism in primed eggplant(Solanum melongena L.)seeds in order to identify hallmarks(expression patterns of antioxidant/DNA repair genes combined with free radical profiles)useful to discriminate between high-and lowquality *** hydropriming protocol hereby developed anticipated(or even rescued)germination,when applied to lots with variable ***(reactive oxygen species)raised during hydropriming and dropped after *** of antioxidant/DNA repair genes was observed during hydropriming and the subsequent *** of SmOGG1(8-oxoguanine glycosylase/lyase)gene detected in primed seeds at 2 h of imbibition appeared as a promising *** the basis of these results,the investigation was restricted within the first 2 h of imbibition,to verify whether the molecular landscape was reproducible in different lots.A complex pattern of antioxidant/DNA repair gene expression emerged,reflecting the preponderance of seed lot-specific *** the low-quality eggplant seeds subjected to hydropriming showed enhanced ROS levels,both in the dry and imbibed state,and this might be a useful signature to discriminate among *** plasticity of eggplant pre-germinative metabolism stimulated by priming imposes a plethora of heterogeneous molecular responses that might delay the search for quality ***,the information hereby gained could be translated to eggplant wild relatives to speed-up their use in breeding programs or other agronomical applications.

关键词： metabolism dynamics gained

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Identification of Characteristic Values in Impulse-Based Processes Using Small Specimens

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Nanomanufacturing and Metrology 2022年第3期5卷 310-323页

作者： Tobias valentino Tim Radel BIAS-Bremer Institut Fur Angewandte Strahltechnik GmbH Klagenfurter StraBe 528359 BremenGermany

Suitable approaches are needed for rapid and cost-efficient materials ***-throughput experimentation reduces the identification time of suitable material *** approach is to use small specimen geometries to save additional production ***,research is continuously being conducted on a new hardness test based on laser-induced shock *** far,characteristic values from the induced indentations have been extracted,which correlate with hardness and tensile ***,the indentation result varies in dependence of the specimen size and *** condition hinders the correlation between characteristic values and material ***,the goal was to induce similar indentation results to minimum specimen ***,different mounting materials and methods were *** created indentations were compared with those induced in large *** mounting parameters were derived from the ***,small specimens can be used for material characterization by considering these mounting parameters.

关键词： Mounting Stiffness Coefficient of restitution Forming efficiency Measuring instrument TEA-CO_(2)laser

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Spontaneous gastric hematoma as a rare cause of acute abdomen:A case report

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World Journal of Clinical Cases 2023年第36期11卷 8551-8556页

作者： Ivan Budimir MirnaŽulec Ksenija Eljuga MarcelŽidak valentino Lisek Department for Plastic and Reconstructive Surgery University Hospital DubravaZagreb 10000Croatia Zagreb School of Medicine University of ZagrebZagreb 10000Croatia Faculty of Medicine Osijek Josip Juraj Strossmayer University of OsijekOsijek 31000Croatia Department of Nursing Catholic University of CroatiaZagreb 10000Croatia Department of Nursing Bjelovar University of Applied SciencesBjelovar 43000Croatia Department of Surgery University of ZagrebDubrava University HospitalZagreb 10000Croatia Department of Abdominal Surgery University Hospital DubravaZagreb 10000Croatia Doctoral Study of Biomolecular Sciences Josip Juraj Strossmayer University of OsijekOsijek 31000Croatia

BACKGROUND Spontaneous gastric hematoma is an exceedingly rare condition characterized by the accumulation of blood within the gastric wall without any apparent iatrogenic or traumatic *** are the most frequent cause of gastric ***,other causes include amyloidosis,pancreatitis,visceral vas-cular aneurysms,endoscopy complications and *** pathophysiology of spontaneous gastric hematoma is not completely ***,it is postulated that it is caused by disruption of submucosal vessels that leads to dissection of the muscularis layer and formation of false *** rarity of this condition increases the challenge of diagnosis,and there is no standard treatment *** SUMMARY We present the case of a spontaneous gastric hematoma in a 22-year-old *** presented to our emergency department complaining of pain in the left flank area lasting for 2 *** was no history of trauma,antico-agulant medications or endoscopy *** hemoglobin and hematocrit levels were slightly lower than ***-slice computed tomography,ultrasound and endoscopy confirmed a gastric intramural *** recommended conservative treatment because there was no hemodynamic instability nor significant *** patient responded well,and there were no unexpected *** the 3-mo follow-up,the ultrasound exa-mination revealed complete regression of the *** After reviewing the literature and our experience,we recommend that more of these cases should be treated *** tendency to treat these cases with potentially burdensome procedures such as total or subtotal gastrectomy should be significantly reduced.

关键词： Spontaneous Intramural hematoma Stomach Acute abdomen Conservative treatment Case report

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Antibacterial property of a gradient Cu-bearing titanium alloy by laser additive manufacturing

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Rare Metals 2022年第2期41卷 580-593页

作者： Dong-Yang Fan Zhe Yi Xu Feng Wen-Zhi Tian Da-Ke Xu A.M.Cristino valentino Qiang Wang Hong-Chen Sun School and Hospital of Stomatology China Medical UniversityLiaoning Provincial Key Laboratory of Oral DiseasesShenyang 110002China Shenyang National Laboratory for Materials Science Key Laboratory for Anisotropy and Texture of Materials(Ministry of Education)School of Materials Science and EngineeringNortheastern UniversityShenyang 110819China Department of Electromechanical Engineering University of MacaoAvenida da UniversidadeTaipaMacaoChina

Streptococcus mutans(***)is the most common cariogenic bacteria and causes caries by forming biofilms.A novel gradient Cu-bearing titanium alloy(TC4-5Cu/TC4)was manufactured using selective laser melting(SLM)technology for dental applications,which is anticipated to inhibit the formation of *** this study,the released concentration of copper ions in both minimum inhibitory concentration(MIC)and minimum bactericidal concentration(MBC)was tested in order to assess the antibacterial property of the alloy against planktonic ***,and the antibacterial and antibiofilm efficiencies of TC4-5Cu/TC4 alloy against sessile *** were evaluated via quantitative antibacterial tests and biofilm *** transcription polymerase chain reaction(RT-PCR)was performed to analyze the expression of biofilm-related genes(gtfB,gtfC,gtfD,ftf and gbpB)and acid production-related gene(ldh).The results suggested that the MIC and MBC of Cu^(2+)were much higher than the release concentration of copper ions of the alloy,which was consistent with the lack of antibacterial effect against planktonic *** the contrary,TC4-5Cu/TC4 alloy exhibited significant bactericidal property against the sessile bacteria and efficient biofilm-restrained ability,and all genes detected in this research were *** results indicated that the TC4-5Cu/TC4 alloy suppressed biofilm formation and the sessile bacterial viability by down-regulating biofilm-related genes.

关键词： Copper Titanium alloys Biofilm Antibacterial property Streptococcus mutans

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Coronal plane deformity around the knee in the skeletally immature population:A review of principles of evaluation and treatment

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World Journal of Orthopedics 2022年第5期13卷 427-443页

作者： valentino Coppa Mario Marinelli Roberto Procaccini Danya Falcioni Luca Farinelli Antonio Gigante Clinical Orthopaedics Department of Clinical and Molecular SciencesUniversitàPolitecnica delle MarcheAncona 60121Italy

Coronal plane deformity around the knee,also known as genu varum or genu valgum,is a common finding in clinical practice for pediatricians and *** deformities can be physiological or *** untreated,pathological deformities can lead to abnormal joint loading and a consequent risk of premature *** aim of this review is to provide a framework for the diagnosis and management of genu varum and genu valgum in skeletally immature patients.

关键词： Genu varum Genu valgum Pediatric deformity Knee deformity Guided growth Osteotomy Lower limb deformity

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Carbonized waste milk powders as cathodes for stable lithium-sulfur batteries with ultra-large capacity and high initial coulombic efficiency

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Green Energy & Environment 2022年第5期7卷 1071-1083页

作者： Rabia Khatoon Sanam Attique Rumin Liu Sajid Rauf Nasir Ali Luhong Zhang Yu-Jia Zeng Yichuan Guo Yusuf valentino Kaneti Jongbeom Na Haichao Tang Hongwen Chen Yang Tian Jianguo Lu State Key Laboratory of Silicon Materials Key Laboratory for Biomedical Engineering of Ministry of EducationSchool of Materials Science and EngineeringZhejiang UniversityHangzhou310027China Institute for Composites Science Innovation School of Materials Science and EngineeringZhejiang UniversityHangzhou310027China Hubei Collaborative Innovation Centre for Advanced Organic Chemical Materials Faculty of Physics and Electronic ScienceHubei UniversityWuhanHubei430062China State Key Laboratory for Silicon Materials Key Laboratory of Quantum Technology and DevicesDepartment of PhysicsZhejiang UniversityHangzhou310027China College of Physics and Optoelectronic Engineering Shenzhen UniversityShenzhen518060China International Center for Materials Nanoarchitectonics(WPI-MANA) National Institute for Materials Science(NIMS)1-1NamikiIbaraki305-0044Japan School of Chemical Engineering&Australian Institute for Bioengineering and Nanotechnology(AIBN) The University of QueenslandBrisbaneQLD4072Australia

To explore the natural resources as sustainable precursors offers a family of green *** use of bio-waste precursors especially the remaining from food processing is a scalable,highly abundant,and cost-effective *** waste materials is highly important especially for new materials discovery in emerging energy storage technologies such as lithium sulfur batteries(LSBs).Herein,waste milk powder is carbonized and constructed as the sulfur host with the hollow micro-/mesoporous framework,and the resulting carbonized milk powder and sulfur(CMP/S) composites are employed as cathodes for *** is revealed that the hollow micro-/mesoporous CMP/S framework can not only accommodate the volume expansion but also endow smooth pathways for the fast diffusion of electrons and Li-ions,leading to both high capacity and long cycling *** CMP/S composite electrode with 56 wt% loaded sulfur exhibits a remarkable initial capacity of 1596 mAh g^(-1) at 0.1 C,corresponding to 95% of the theoretical *** at a rate of 1 C,it maintains a high capacity of 730 mAh g^(-1) with a capacity retention of 72.6% after 500 cycles,demonstrating a very low capacity fading of only 0.05% per ***,the Coulombic efficiency is always higher than 96%during all the *** only used source material is expired waste milk powders in our *** believe that this "trash to treasure" approach will open up a new way for the utilization of waste material as environmentally safe and high performance electrodes for advanced LSBs.

关键词： composites powders initial

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Gut microbiota and COVID-19: An intriguing pediatric perspective

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World Journal of Clinical Cases 2022年第23期10卷 8076-8087页

作者： Maria Sole valentino Claudia Esposito Simone Colosimo Angela Maria Caprio Simona Puzone StefanoGuarino Pierluigi Marzuillo Emanuele Miraglia del Giudice Anna Di Sessa Department of Woman Childand General and Specialized SurgeryUniversity of Campania Luigi VanvitelliNaples 80138Italy

Gastrointestinal(GI)involvement has been reported in approximately 50%of patients with coronavirus disease 2019(COVID-19),which is due to the pathogenic role of inflammation and the intestinal function of the angiotensinconverting enzyme 2 and its *** adult data has pointed out that gut dysbiosis might occur in these patients with a potential impact on the severity of the disease,however the role of gut microbiota in susceptibility and severity of COVID-19 disease in children is still poorly *** the last decades,the crosstalk between gut and lung has been largely recognized resulting in the concept of“gut-lung axis”as a central player in modulating the development of several *** organs are involved in the common mucosal immune system(including bronchus-associated and gut-associated lymphoid tissues)and their homeostasis is crucial for human *** this framework,it has been found that the role of GI dysbiosis is affecting the homeostasis of the gutliver *** note,a gut microbiome imbalance has been linked to COVID-19 severity in adult subjects,but it remains to be *** on the increased risk of inflammatory diseases in children with COVID-19,the potential correlation between gut microbiota dysfunction and COVID-19 needs to be studied in this *** aimed to summarize the most recent evidence on this striking aspect of COVID-19 in childhood.

关键词： Gut Microbiota Dysbiosis Microbiome COVID-19 Children

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The multifaceted PDCD10/CCM3 gene

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Genes & Diseases 2021年第6期8卷 798-813页

作者： Mariaelena valentino Elisabetta Dejana Matteo Malinverno The FIRC Institute of Molecular Oncology(IFOM) Milan1620139Italy Department of Oncology and Haemato-Oncology University of MilanMilan720122Italy Vascular Biology Department of ImmunologyGenetics and PathologyUppsala UniversityUppsalaSE-75105Sweden

The programmed cell death 10(PDCD10)gene was originally identified as an apoptosis-related gene,although it is now usually known as CCM3,as the third causative gene of cerebral cavernous malformation(CCM).CCM is a neurovascular disease that is characterized by vascular malformations and is associated with headaches,seizures,focal neurological deficits,and cerebral *** PDCD10/CCM3 protein has multiple subcellular localizations and interacts with several multi-protein complexes and signaling *** PDCD10/CCM3 governs many cellular functions,which include cell-to-cell junctions and cytoskeleton organization,cell proliferation and apoptosis,and exocytosis and *** its central role in the maintenance of homeostasis of the cell,dysregulation of PDCD10/CCM3 can result in a wide range of altered cell *** can lead to severe diseases,including CCM,cognitive disability,and several types of ***,we review the multifaceted roles of PDCD10/CCM3 in physiology and pathology,with a focus on its functions beyond CCM.

关键词： Cancer Cell signaling Cell-cycle Neurovascular unit PDCD10/CCM3

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Spatial-controlled etching of coordination polymers

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Chinese Chemical Letters 2021年第2期32卷 635-641页

作者： Qi Dang Yucen Li Wei Zhang Yusuf valentino Kaneti Ming Hu Yusuke Yamauchi School of Physics and Electronic Science.East China Normal University Shanghai 200241China International Center for Materials Nanoarchitectonics(MANA) National Institute for Materials Science(NIMS)Ibaraki 305-0044Japan School of Chemical Engineering and Australian Institute for Bioengineering and Nanotechnology(A1BN) The University of QueenslandQueensland 4072Australia Department of Plant and Environmental New Resources Kyung Hee University.Gyeonggi-do 446-701South Korea

Nanoarchitectonics provide versatile opportunities for modifying the properties of coordination polymers(CP) other than molecular ***-controlled etching focuses on the controlled disassembly of the *** etching method provides an excellent opportunity for tailoring the properties and functions of the ***,we discuss the mechanism for controlled etching of the CPs and summarized the two main strategies utilized so *** examples are illustrated to demonstrate recent developments in this ***,advantages of the etched CPs are summarized in several important applications,including energy storage,catalysis and nanomedicine.

关键词： Coordination polymer Metal-organic frameworks Etching Hollow structure Sodium ion battery Catalysis Nanomedicine

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Contrasting responses of native and alien plant species to soil properties shed new light on the invasion of dune systems

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Journal of Plant Ecology 2020年第6期13卷 667-675页

作者： Stefano Vitti Elisa Pellegrini valentino Casolo Giacomo Trotta Francesco Boscutti Department of Life Sciences University of TriesteVia L.Giorgieri 1034127 TriesteItaly Department of Agricultural FoodEnvironmental and Animal SciencesUniversity of Udinevia delle Scienze 91Udine 33100Italy Department of Biology University of CopenhagenUniversitetsparken 42100 KøbenhavnØDenmark

在陆地生态系统中,沿海沙丘特别容易受到外来植物的入侵。许多研究将沙丘生境的入侵归因于人为因素,但对土壤性质和植物性状在植物入侵中的作用却知之甚少。本研究考察了沙丘系统土壤特征与外来植物入侵的关系,重点研究了土壤养分、土... 详细信息

在陆地生态系统中,沿海沙丘特别容易受到外来植物的入侵。许多研究将沙丘生境的入侵归因于人为因素,但对土壤性质和植物性状在植物入侵中的作用却知之甚少。本研究考察了沙丘系统土壤特征与外来植物入侵的关系,重点研究了土壤养分、土壤盐分和植物功能特征之间的相互作用。研究地点是马拉诺和格拉多泻湖(北亚得里亚海)的沙质堰洲岛。根据沙丘系统生态梯度上的主要生境(前沙丘、后沙丘和盐沼),在10个区域内选择100个地块(4 m×4 m)。在每个地块中记录所有植物物种的发生和丰度,并收集一个土壤核。对每个土壤样品进行土壤质地、电导率(代表土壤盐分)、有机碳和氮含量分析,并与本地和外来植物的种类数和覆盖度相关联。分析外来和本地物种主要的生殖功能和营养功能性状在生境中的变化。研究结果表明,土壤性质对外来物种库和本地物种库的影响不同,与植物整体多样性密切相关。在后沙丘(最易入侵)的生境中,高的土壤导电性限制了外来物种的数量,但土壤有机碳含量随着外来植物丰度的增加而增加,这也表明植物入侵与土壤之间存在潜在的反馈过程。只有在后沙丘生境中,随着环境条件的改善和植物竞争的加剧,本地植物和外来植物的功能性状谱有显著的趋同。本研究结果表明,在恶劣条件下,只有本地特有植物才能茁壮成长,而在中等条件下,土壤特性梯度与植物特性协同作用,抑制/促进外来植物丰富度。

关键词：外来入侵物种功能特性土壤养分植物群落沙丘系统

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