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Management of chronic heart failure:Role of home echocardiography in monitoring care programs

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World Journal of Cardiology 2012年第3期4卷 72-76页

作者： Silvia Soreca Sergio Aprile Andrea Cardone Giovanni Carella Biagio Fimiani Franco Guarnaccia Giosuè Santoro valentina Apuzzi Giorgio Bosso Antonio Valvano Giovanni Zito Ugo Oliviero Associazioni Regionali Cardiologi Ambulatoriali CampaniaVia M.Testa 884127 SalernoItaly Department of Clinical Medicine and Cardiovascular Sciences Federico Ⅱ UniversityVia S.Pansini 580131 NaplesItaly

AIM:To identify a possible role of home echocardiography for monitoring chronic heart failure(CHF)***:We prospectively investigated 118 patients hospitalized during the last year for CHF who could not easily reach the pertaining District Healthcare *** patients were followed up with 2 home management programs:one including clinical and electrocardiographic evaluations and also periodic home echocardiographic examinations(group A),the other including clinical and electrocardiographic evaluations only(group B).RESULTS:At the end of the 18-mo follow-up no significant differences were observed between the 2 groups as regards the primary endpoint:rehospitalization occurred in 4 patients of the group A and in 6 patients of the group B;major cardiovascular events occurred in 2 and in 3 patients,*** significant differences were observed with respect to the secondary endpoints:one vascular event appeared in both the groups,3 cardiovascular deaths occurred in group A and 2 in group *** significant differences were observed between the 2 groups as regards the composite endpoint of death plus ***:Home echocardiography for monitoring of CHF patients does not improve the cardiovascular *** our CHF patients,a low incidence of vascular events was observed.

关键词： Echocardiography Chronic heart failure Home monitoring Care programs Cardiovascular events

One Aim-Several Goals： From Stem Cell to the Biofuel Production. The New Background Method for Zero Waste and High Efficiency Biodiesel Production from Microalgae Chlorella Vulgaris

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材料科学与工程（中英文A版） 2014年第7期4卷 234-240页

作者： Elena V. Orlova Natalya I. Minkevich Olga V. Prusakova valentina S. Orlova Artem M. Ermakov Evgeny I. Maevsky Stem Cells Technique & Nanocomposite Materials Group Institute of Theoretical and Experimental Biophysics (ITEB) RASMoscow District 142290 Russia Laboratory of Biological Systems Energy Institute of Theoretical and Experimental Biophysics (ITEB) RAS Moscow District142290 Russia Laboratory of Hormonal Regulation Proteins of Shemyakin & Ovchinnikov Institute of Bioorganic Chemistry RAS Moscow11799 7 Russia Laboratory of Cell Engineering Institute of Theoretical and Experimental Biophysics (ITEB) R.AS Moscow District 142290 Russia Ecology Faculty System Ecology Chair Peoples' Friendship University of Russia Moscow 115093 Russia

Here, "one aim-several goals" background method for boosting (activating) biomaterials by weak low frequency magnetic field for many branches of biotechnology and medicine was presented. Our original method allows us to activate for the one hand the growth and reproduction of stem cells without any cancer transformations, with de novo expression of mRNA MDR gene, decreased apoptotic effects and in the required amount which could be the very important application in many branches of cancer therapy with standard chemotherapy procedures and without any fear about possible stem cells transformation into cancer cells. But for another hand it also could be the way for the biofuel production from microalgae Chlorella vulgaris. Such biofuel could be produced quickly and in large volumes, and biosafety waste products could use as a tool for rehabilitation of tsunami or radiation-affected soils

关键词：燃料生产生物柴油干细胞小球藻微藻废物癌症治疗低频弱磁场

Impaired diastolic function in nave untreated human immunodeficiency virus infected patients

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World Journal of Cardiology 2010年第4期2卷 98-103页

作者： Ugo Oliviero Giovanni Bonadies Giorgio Bosso Maria Foggia valentina Apuzzi Mariarosaria Cotugno Antonio Valvano Enrico Leonardi Guglielmo Borgia Giuseppe Castello Raffaele Napoli Luigi Saccà Department of Inter-nal Medicine University Federico Ⅱ80131 NaplesItaly Department of Infectious Diseases University Federico Ⅱ80131 NaplesItaly National Cancer Institute G.Pascale Foundation80131 NaplesItaly

AIM:To evaluate cardiac function and structure in un-treated human immunodeficiency virus(HIV) patients without clinical evidence of cardiovascular ***:Fifty-three nave untreated HIV-infected patients and 56 healthy control subjects underwent clinical assessment,electrocardiography(ECG) and echocardiography,including tissue doppler ***,a set of laboratory parameters was obtained from all subjects,including HIV-RNA plasma levels,CD4 cell counts and tumor necrosis factor-α ***:The two groups showed normal ECG traces and no differences regarding systolic morphologic *** contrast,a higher prevalence of left ventricular diastolic dysfunction(abnormal relaxation or pseudonormal filling pattern) was found in the HIV patients(36% vs 9% in patients and controls,respec-tively,P <0.001).CONCLUSION:Subclinical cardiac abnormalities ap-pear in an early stage of the HIV infection,indepen-dent of antiretroviral *** data suggest that HIV per se plays a role in the genesis of diastolic dys-function.

关键词： Diastolic function Human immunodeficiency virus Naive subjects Cardiovascular risk factors

Electrical storm: A clinical and electrophysiological overview

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World Journal of Cardiology 2015年第9期7卷 555-561页

作者： Sergio Conti Salvatore Pala Viviana Biagioli Giuseppe Del Giorno Martina Zucchetti Eleonora Russo Vittoria Marino Antonio Dello Russo Michela Casella Francesca Pizzamiglio valentina Catto Claudio Tondo Corrado Carbucicchio Cardiac Arrhythmia Research Centre Centro Cardiologico Monzino IRCCS

Electrical storm(ES) is a clinical condition characterized by three or more ventricular arrhythmia episodes leading to appropriate implantable cardioverterdefibrillator(ICD) therapies in a 24 h period. Mostly, arrhythmias responsible of ES are multiple morphologies of monomorphic ventricular tachycardia(VT), but polymorphic VT and ventricular fibrillation can also result in ES. Clinical presentation is very dramatic in most cases, strictly related to the cardiac disease that may worsen electrical and hemodynamic decompensation. Therefore ES management is challenging in the majority of cases and a high mortality is the rule both in the acute and in the long-term phases. Different underlying cardiomyopathies provide significant clues into the mechanism of ES, which can arise in the setting of structural arrhythmogenic cardiomyopathies or rarely in patients with inherited arrhythmic syndrome, impacting on pharmacological treatment, on ICD programming, and on the opportunity to apply strategies of catheter ablation. This latter has become a pivotal form of treatment due to its high efficacy in modifying the arrhythmogenic substrate and in achieving rhythm stability, aiming at reducing recurrences of ventricular arrhythmia and at improving overall survival. In this review, the most relevant epidemiological and clinical aspects of ES, with regard to the acute and long-term follow-up implications, were evaluated, focusing on these novel therapeutic strategies of treatment.

关键词： Electrical storm Ventricular tachycardia/ fibrilla

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大喇叭

住区 2014年第6期 81-85页

作者： Einar Bye Cyril Chabaud Pablo Fernndez Federica Frangipane Styrkaar Hustveit Fanny Jacquet Christian O' Riordan Larsen Quentin Leroy Mélanie Mathevet Runar Nedregàrd Ines Rakow Kévin Sanouiller valentina Serra Bergur Porsteinsson Martin Bergsmark Vodde Henning Aschim Wien Geir Brendeland Bergur Briem Stig Arne Heltorp NTNU

这个建筑装置是由Brendeland和Kristoffersen指导,由来自挪威科技大学的一群国际硕士研究生建造完成的.它是一个纪念碑、雕塑、运动场、城市扩音器、扬声器、声音接收器、舞台、电影放映台、遮蔽物、共鸣箱、乐器、一种数学公式、一个... 详细信息

这个建筑装置是由Brendeland和Kristoffersen指导,由来自挪威科技大学的一群国际硕士研究生建造完成的.它是一个纪念碑、雕塑、运动场、城市扩音器、扬声器、声音接收器、舞台、电影放映台、遮蔽物、共鸣箱、乐器、一种数学公式、一个感性经验和科学实验的工具、一个再利用的机械零件.这是挪威科技大学送给特隆赫姆市的建校100周年的纪念礼物.地段位于特隆赫姆市历史中心的一个小公园里,旁边是一个中世纪教堂.百年纪念活动结束之后,它将会搬到峡湾一个美丽的、永久的地点,作为大学的百年纪念碑.这个由柱形钢结构支撑的截锥型构筑物,厚3mm,长18m,高6.5m,重达12吨.

关键词：喇叭科技大学百年纪念活动硕士研究生纪念碑电影放映数学公式科学实验

A STUDY ON THE EFFECTS OF MYRICETIN ON ENDOTHELIAL INJURY IN A CELLULAR MODEL OF HYPERHOMOCYSTEINAEMIA

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World Journal of Traditional Chinese Medicine 2016年第2期 93-93页

作者： Antony Kam valentina Razmovski-Naumovski Kong M.Li Srinivas Nammi Kelvin Chan George Q.Li Faculty of Pharmacy University of Sydney School of Biological Sciences Nanyang Technological University National Institute of Complementary Medicine Western Sydney University South Western Sydney Clinical School School of Medicine University of New South Wales Discipline of Pharmacology Sydney Medical SchoolUniversity of Sydney School of Science and Health Western Sydney University School of Pharmacy & Biomolecular Sciences Liverpool John Moores Univerversity

Objectives:An increase in homocysteine and adenosine levels results in S-adenosylhomocysteine accumulation,and sensitise TNF-induced cytotoxicity[1].In the search of natural products with beneficial effects against

关键词： TNF A STUDY ON THE EFFECTS OF MYRICETIN ON ENDOTHELIAL INJURY IN A CELLULAR MODEL OF HYPERHOMOCYSTEINAEMIA

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活态遗产:锡耶纳数字生态博物馆

国际博物馆 2018年第3期 47-55页

作者：伊丽莎·布鲁特尼瓦伦蒂娜·鲁西尼路易吉·迪·克拉托吴佳欣(译) 锡耶纳博物馆基金会锡耶纳大学佛罗伦萨美术学院米兰卡托利卡大学经济系国际博物馆协会不详

2012年,锡耶纳博物馆基金会提出并规划锡耶纳数字生态博物馆项目,将其视为重启锡耶纳博物馆服务战略计划的一部分。该战略计划曾于2011年获得联邦文化管理奖,旨在巩固创建成熟文化区,整合该地区物质和非物质文化遗产、博物馆藏品、自然... 详细信息

2012年,锡耶纳博物馆基金会提出并规划锡耶纳数字生态博物馆项目,将其视为重启锡耶纳博物馆服务战略计划的一部分。该战略计划曾于2011年获得联邦文化管理奖,旨在巩固创建成熟文化区,整合该地区物质和非物质文化遗产、博物馆藏品、自然遗产、文化和知识产业、本地传统特产和基础设施等。数字博物馆项目旨在进一步扩大和开放文化网络,提高文化生产和文化利用的效率,促进建成地域文化特区。数字博物馆秉承基金会的美好愿景—'参观博物馆,领略风土人情',提供多种方式供当地居民和游客体验地方特色。

关键词：生态博物馆锡耶纳基金会

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西57号街公寓

城市环境设计 2019年第2期118卷 228-239页

作者： David Brown Aleksander Tokarz Alessandro Ronfini Alessio Valmori Alvaro Mendive Benjamin Schulte Birk Daugaard Celine Jeanne Christoffer Gotfredsen Daniel Sundlin Dominyka Mineikyte Eivor Davidsen Felicia Guldberg Florian Oberschneider Soren Grunert Gabrielle Nadeau Gül Ertekin Ho Kyung Lee Hongyi Jin Julian Liang Julianne Gola Laura Youf Lucian Racovitan Marcella Martinez Maria Nikolova Maya Shopova Mitesh Dixit Nicklas A.Rasch Ola Hariri Riccardo Mariano Steffan Heath Stanley Lung Tara Hagan Thilani Rajarathna Tyler Polich valentina Mele Valerie Lechene Xu Li Yi Li Aaron Hales Alessandro Ronfini Brian Foster Christoffer Gotfredsen Francesca Portesine Ho Kyung Lee Hongyi Jin Ivy Hume Jenny Chang Lauren Turner Mina Rafiee Rakel Karlsdottir Tara Hagan Thomas Fagan Tiago Barros valentina Mele Iwan Baan 朱翰林

西57号街公寓结合了欧洲庭院建筑和传统曼哈顿高层的特点,并兼具两者的优点:通透的院落建筑的紧凑与高效性以及摩天楼拥有的广阔视野。通过让建筑三个角保持较低姿态而仅将东北角提升至450英尺(约137.2米),使得庭院面向哈德逊河的视野开... 详细信息

西57号街公寓结合了欧洲庭院建筑和传统曼哈顿高层的特点,并兼具两者的优点:通透的院落建筑的紧凑与高效性以及摩天楼拥有的广阔视野。通过让建筑三个角保持较低姿态而仅将东北角提升至450英尺(约137.2米),使得庭院面向哈德逊河的视野开阔,让较低的夕阳也能照进街区深处,并优雅地为一旁的Helena Tower保留河景。建筑的形式随着观察者的位置而不断变换。从西侧的高速公路上看,它

关键词： Section 局部剖面图

黑曲霉MIUG 1.15生产胞外转化酶的研究

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生物技术 1999年第2期9卷 14-16页

作者：钦传光丹.娃楞亭娜巴日姆.加布里拉尼古拉乌.安卡湖北工学院生物工程系加拉兹大学食品工业系

研究黑曲霉ＭＩＵＧ１．１５产生转化酶的条件和特性。表面培养时转化酶的产率较高。每隔６ｄ更换一次培养基，菌种连续发酵４５—５０ｄ后，转化酶活力比最初的高４．７倍。此后，ｐＨ值陡然下降，转化酶迅速失活。转化酶最适宜温度４... 详细信息

研究黑曲霉ＭＩＵＧ１．１５产生转化酶的条件和特性。表面培养时转化酶的产率较高。每隔６ｄ更换一次培养基，菌种连续发酵４５—５０ｄ后，转化酶活力比最初的高４．７倍。此后，ｐＨ值陡然下降，转化酶迅速失活。转化酶最适宜温度４５℃，ｐＨ值４．５，７０℃下热稳定（６０ｍｉｎ内的失活率为５４％）。

关键词：黑曲霉转化酶表面培养发酵条件培养基