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Analytical method for cell displacement defect quantum-dot cellular automata primitive

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Journal of Electronic Science and Technology 2023年第1期21卷 26-34页

作者： vaishali Dhare Usha Mehta Institute of Technology Nirma UniversityAhmedabad382481India

Quantum-dot cellular automata(QCA)is an emerging computational paradigm which can overcome scaling limitations of the existing complementary metal oxide semiconductor(CMOS)*** existence of defects cannot be ignored,considering the fabrication of QCA devices at the molecular level where it could alter the ***,defects in QCA devices need to be *** far,the simulation-based displacement defect analysis has been presented in the literature,which results in an increased demand in the corresponding mathematical *** this paper,the displacement defect analysis of the QCA main primitive,majority voter(MV),is presented and carried out both in simulation and mathematics,where the kink energy based mathematical model is *** results demonstrate that this model is valid for the displacement defect in QCA MV.

关键词： Displacement defect Kink energy Majority voter(MV) Quantum-dot cellular automata (QCA)

Machine learning techniques for prediction of capacitance and remaining useful life of supercapacitors: A comprehensive review

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Journal of Energy Chemistry 2023年第2期77卷 438-451,I0011页

作者： vaishali Sawant Rashmi Deshmukh Chetan Awati Department of Technology Shivaji UniversityKolhapurMaharashtraIndia

Supercapacitors are appealing energy storage devices for their promising features like high power density,outstanding cycling stability,and a quick charge–discharge *** exceptional life cycle and ultimate power capability of supercapacitors are needed in the transportation and renewable energy generation ***,predicting the capacitance and lifecycle of supercapacitors is significant for selecting the suitable material and planning replacement intervals for *** addition,system failures can be better addressed by accurately forecasting the lifecycle of ***,the use of machine learning for performance prediction of energy storage materials has drawn increasing attention from researchers globally because of its superiority in prediction accuracy,time efficiency,and *** article presents a detailed review of the progress and advancement of ML techniques for the prediction of capacitance and remaining useful life(RUL)of *** review starts with an introduction to supercapacitor materials and ML applications in energy storage devices,followed by workflow for ML model building for supercapacitor ***,the summary of machine learning applications for the prediction of capacitance and RUL of different supercapacitor materials including EDLCs(carbon based materials),pesudocapacitive(oxides and composites)and hybrid materials is ***,the general perspective for future directions is also presented.

关键词： Supercapacitors Energy storage materials Artificial neural network Machine learning Capacitance prediction Remaining useful life

Random and Periodic Sleep Schedules for Target Detection in Sensor Networks

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Journal of Computer Science & Technology 2008年第3期23卷 343-354页

作者： vaishali P.Sadaphal Bijendra N.Jain Tata Research Development and Design Centre(TRDDC) PuneIndia Department of Computer Science and Engineering Indian Institute of TechnologyDelhiNew DelhiIndia

We study random and periodic sleep schedules from the point of view of delay in detecting the target. We consider sleep schedules in which a sensor in ＂inactive＂ mode wakes up either randomly or periodically to detect presence of the target within its vicinity resulting into two sleep schedules：（a） random wake-up schedule, and （b） periodic wake-up schedule respectively. Specifically, we analyse and obtain for the random wake-up schedule the expected delay in detection, and the delay, such that with probability P, the delay is less than the computed value. For the periodic wake-up schedule we show that there exists an upper bound on the delay. Further we compute the average value of delay. We have shown that the theoretically computed averages and the upper bounds on the delay match with the simulation results for the random wake-up and periodic wake-up schedules.

关键词： sleep schedule energy conservation target detection

Embryonic modulation through thermal manipulation and in ovo feeding to develop heat tolerance in chickens

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Animal Nutrition 2023年第2期13卷 150-159页

作者： Akshat Goel Chris Major Ncho vaishali Gupta Yang-Ho Choi Department of Animal Science Gyeongsang National UniversityJinju 52828Republic of Korea Institute of Agriculture and Life Sciences Gyeongsang National UniversityJinju 52828Republic of Korea Division of Applied Life Sciences(BK21 Plus Program) Gyeongsang National UniversityJinju 52828Republic of Korea

Healthy chickens are necessary to meet the ever-increasing demand for poultry *** are subjected to numerous stressful conditions under commercial rearing systems,including variations in the envi-ronmental ***,it is difficult to counter the effects of global warming on the livestock *** environmental temperature is a stressful condition that has detrimental effects on growth and production performance,resulting in decreased feed intake,retarded growth,compromised gut health,enhanced oxidative stress,and altered immune *** approaches include nutritional modification and housing management to mitigate the harmful effects of hot ***,broiler chickens are more susceptible to heat stress(HS)than layer chickens because of their high muscle mass and metabolic *** this review,we explored the possibility of in ovo manipulation to combat HS in broiler *** their short lifespan from hatching to market age,embryonic life is thought to be one of the critical periods for achieving these *** embryos can be modulated through either temperature treatment or nourishment to improve thermal tolerance during the rearing *** first provided a brief overview of the harmful effects of HS on *** in-depth evaluation was then presented for in ovo feeding and thermal manipulation as emerging strategies to combat the negative effects of ***,we evaluated a combination of the two methods using the available *** together,these investigations suggest that embryonic manipulation has the po-tential to confer heat resistance in chickens.

关键词： Embryo Thermal manipulation In ovo feeding Heat stress Poultry

Leukocyte adhesion defect:Where do we stand circa 2019?

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Genes & Diseases 2020年第1期7卷 107-114页

作者： Jhumki Das Avinash Sharma Ankur Jindal vaishali Aggarwal Amit Rawat Allergy Immunology Unit Department of PediatricsAdvanced Pediatrics CentrePostgraduate Institute of Medical Education and ResearchChandigarhIndia Department of Pediatrics Dr Rajendra Prasad Government Medical CollegeTandaKangraHimachal PradeshIndia

Migration of polymorphonuclear leukocytes from bloodstream to the site of inflammation is an important event required for surveillance of foreign *** trafficking of leukocytes from bloodstream to the tissue occurs in several distinct steps and involves several adhesion *** in adhesion of leukocytes to vascular endothelium affecting their subsequent migration to extravascular space gives rise to a group of rare primary immunodeficiency diseases(PIDs)known as Leukocyte Adhesion Defects(LAD).Till date,four classes of LAD are discovered with LAD I being the most common *** I is caused by loss of function of common chain,cluster of differentiation(CD)18 of β2 integrin *** patients suffer from life-threatening bacterial infections and in its severe form death usually occurs in childhood without bone marrow *** II results from a general defect in fucose *** patients suffer from less severe bacterial infections and have growth and mental *** blood group phenotype is also observed in these *** III is caused by abnormal integrin *** III patients suffer from severe bacterial and fungal *** frequently show delayed detachment of umbilical cord,impaired wound healing and increased tendency to *** IV is the most recently described *** is caused by defects in β2 and α4β1 integrins which impairs lymphocyte *** IV patients have monogenic defect in cystic-fibrosis-transmembraneconductance-regulator(CFTR)gene,resulting in cystic *** and genetic etiology of all LAD syndromes are discussed in detail in this paper.

关键词： Neutrophilic defect Neutrophilic leukocytosis Phagocyte rolling Phagocytes Primary immunodeficiency disorders

Vitamin D,calcium homeostasis and aging

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Bone Research 2016年第3期4卷 133-139页

作者： vaishali Veldurthy Ran Wei Leyla Oz Puneet Dhawan Yong Heui Jeon Sylvia Christakos Department of Microbiology Biochemistry and Molecular GeneticsRutgersThe State University of New JerseyNew Jersey Medical School

Osteoporosis is characterized by low bone mass and microarchitecture deterioration of bone tissue, leading to enhanced bone fragility and consequent increase in fracture risk. Evidence is accumulating for an important role of calcium deficiency as the process of aging is associated with disturbed calcium balance. Vitamin D is the principal factor that maintains calcium homeostasis. Increasing evidence indicates that the reason for disturbed calcium balance with age is inadequate vitamin D levels in the elderly. In this article, an overview of our current understanding of vitamin D, its metabolism, and mechanisms involved in vitamin D-mediated maintenance of calcium homeostasis is presented. In addition, mechanisms involved in age-related dysregulation of 1,25（OH）2D3 action, recommended daily doses of vitamin D and calcium, and the use of vitamin D analogs for the treatment of osteoporosis （which remains controversial） are reviewed. Elucidation of the molecular pathways of vitamin D action and modifications that occur with aging will be an active area of future research that has the potential to reveal new therapeutic strategies to maintain calcium balance.

关键词： BMD VDR Vitamin D,calcium homeostasis and aging

Recent advances in elucidating the genetics of common variable immunodeficiency

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Genes & Diseases 2020年第1期7卷 26-37页

作者： vaishali Aggarwal Aaqib Zaffar Banday Ankur Kumar Jindal Jhumki Das Amit Rawat Allergy and Immunology Unit Department of PediatricsAdvanced Pediatrics CentrePostgraduate Institute of Medical Education and ResearchChandigarhIndia

Common variable immunodeficiency disorders(CVID),a heterogeneous group of inborn errors of immunity,is the most common symptomatic primary immunodeficiency *** with CVID have highly variable clinical *** the advent of whole genome sequencing and genome wide association studies(GWAS),there has been a remarkable improvement in understanding the genetics of *** has also helped in understanding the pathogenesis of CVID and has drastically improved the management of these patients.A multiomics approach integrating the DNA sequencing along with RNA sequencing,proteomics,epigenetic and metabolomics profile is the need of the hour to unravel specific CVID associated disease pathways and novel therapeutic *** this review,we elaborate various techniques that have helped in understanding the genetics of CVID.

关键词： Common variable immunodeficiency(CVID) Epigenome Genetics Next generation sequencing(NGS) Transcriptome

Design and development of a plastic scintillator based whole body β/γ contamination monitoring system

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Nuclear Science and Techniques 2021年第5期32卷 33-42页

作者： vaishali M.Thakur Amit Jain P.Ashokkumar Rekha Anilkumar Pravin Sawant Probal Chaudhury L.M.Chaudhari Radiation Safety Systems Division Bhabha Atomic Research CentreMumbai 400085India Health Physics Division Bhabha Atomic Research CentreMumbai 400085India Department of Physics Nowrosjee Wadia CollegePuneMaharashtra 411001India

Plastic scintillation detectors based whole body β/γ contamination monitors are developed for use in radiation *** microcontroller-based multi-detector system uses 13 plastic scintillator detectors,with minimized dead detection zones,monitoring the whole body,and conforming to the contamination limit prescribed by the regulatory *** system has the features for monitoring hands,feet,head,and faceβ/γusing contamination monitors and portal exit *** can detect gamma sources at a dose rate of 10 n Gyh^(-1).The system is calibrated using b sources^(90)Sr/^(90)Y,^(204)Tl,and^(36)Cl,and the efficiency is found to be 29%,22%,and 18%,***β/γcontaminationis0.15 Bqcm^(-2),which is significantly less than the minimum detection objectives on head,face,hands,and feet.

关键词： Plastic scintillation detector Contamination monitor Microcontroller Minimum Detection Objective(MDO) Minimum Detection Concentration(MDC)

Elimination of lymphatic filariasis:Where do we stand so far?

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Asian Pacific Journal of Tropical Medicine 2023年第9期16卷 385-399页

作者： Aashna Sinha Sudhashekhar Kumar Deen Dayal vaishali Yadav Atreyi Pramanik Kundan Kumar Chaubey Sanjay Kumar Division of Research and Innovation School of Applied and Life SciencesUttaranchal UniversityArcadia GrantP.O.ChandanwariPremnagarDehradunUttarakhand-248007India Department of Physiology School of Medical Science and ResearchSharda UniversityGreater NoidaUP-201310India Department of Biotechnology GLA UniversityMathuraUP-281406India Department of Microbiology Central University of Haryana123031India School of Basic and Applied Sciences Sanskriti UniversityMathuraUttar Pradesh-281401India Biological and Bio-computational Lab Department of Life ScienceSharda School of Basic Sciences and ResearchSharda UniversityGreater NoidaUP-201310India

Lymphatic filariasis(LF),an asymptomatic,acute,and chronic condition in human beings,is the second most common vector-borne disease after *** to the World Health Organization,there are 120 million LF cases detected in 81 tropical and subtropical countries,and one billion people are at ***,the Global Program to Eliminate Lymphatic Filariasis was launched in 2000,with the primary objective of stopping LF transmission among all at-risk groups using mass drug administration(MDA),managing morbidities,and preventing LF-related impairments using a minimum treatment ***,other programs such as epidemiological assessment including National Filaria Control Program and World Health Organization recommended routine and pre-MDA microfilaremia surveys also implemented to stop the LF *** routine filaria surveys were also carried out in around 2000-4000 individuals/month throughout the year whereas pre-MDA surveys were also conducted every year in approximately 4000 individuals in four fixed and four random ***,the Transmission Assessment Survey was also conducted to check the risk of LF among primary school ***,potential diagnostic methods,systematic surveillance regimes,the Direct Network Report system,and regular trainings and awareness may be also effective in preventing the recurrence of ***,this review emphasizes the potential advocacy tools and various strategies as well as procedures for monitoring,which could be impactful in eliminating LF.

关键词： Lymphatic filariasis Treatment Challenges Prospect Elimination