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Fun.al div.rsity n.tes 253-366:taxon.mic an. phylogen.tic con.ribution. to fun.al taxa

Fun.al Div.rsity 2016年第3期78卷 1-237页

作者： Guo Jie Li Kev.n.D.Hyde Rui Lin.Zhao Sin.n. Hon.san.n.Faten.Awad Abdel-Aziz Mohamed A.Abdel-Wahab Pablo Alv.rado Gen.v.ldo Alv.s-Silv. Joseph F.Ammirati Hiran.A.Ariyawan.a Abhishek Baghela Ali Hassan.Bahkali Michael Beug D.Jayarama Bhat Dimitar Bojan.chev.Thitiya Boon.ratuan. Timur S.Bulgakov.Erio Camporesi Marcela CBoro Oldriska Ceska Dyutiparn. Chakraborty Jia Jia Chen.K.W.Thilin. Chethan. Putarak Chomn.n.i Giov.n.i Con.iglio Bao Kai Cui Don. Qin.Dai Yu Chen. Dai Din.shan. A.Daran.gama Kan.d Das Mon.ka C.Dayarathn. Eske De Crop Rafael J.v.De Oliv.ira Carlos Alberto Fragoso de Souza JoséIde Souza Bryn.T.M.Den.in.er Asha J.Dissan.yake Min.kwan.Doilom E.Ricardo Drechsler-San.os Masoomeh Ghobad-n.jhad Sean.P.Gilmore Aristóteles Góes-n.to MichałGorczak Charles H.Haitjema Kalan. Kan.han. Hapuarachchi Akira Hashimoto Mao Qian. He John.K.Hen.ke Kazuyuki Hirayama Maria J.Iribarren.Subashin. C.Jayasiri Ruv.shika S.Jayawarden. Sun.Jeon. Jeon.Gustav. H.Jerôn.mo An. L.Jesus E.B.Gareth Jon.s Ji Chuan.Kan. Saman.ha C.Karun.rathn. Paul M.Kirk Sirin.pa Kon.a Eric Kuhn.rt Ewald Lan.er Haen. Sub Lee Hyan. Burm Lee Wen.Jin. Li Xin. Hon. Li Kare Liimatain.n.Diogo Xav.er Lima Chuan.Gen.Lin.Jian.Kui Liu Xin.s Zhon. Liu Zuo Yi Liu J.Jen.ifer Luan.sa-ard Robert Lückin. H.Thorsten.Lumbsch Saisamorn.Lumyon. Eduardo M.Leaño Agostin. v.Maran. Misato Matsumura Eric H.C.McKen.ie Suchada Mon.kolsamrit Peter E.Mortimer Thi Thuon. Thuon. n.uyen.Tuula n.skan.n.Chada n.rphan.houn.Michelle A.O’Malley Sittiporn.Parn.en.Julia Pawłowska Rekhan. H.Perera Run.tiwa Phookamsak Chayan.rd Phukhamsakda Carmen.L.A.Pires-Zottarelli Oliv.er Raspé Mateus A.Reck Sarah C.O.Rocha An.réL.C.M.Ade San.iago In.un.l C.Sen.n.yake Ledo Setti Qiu Ju Shan. San.ay K.Sin.h Esteban.B.Sir Kev.n.v.Solomon.Jie Son. Prasert Srikitikulchai Marc Stadler Satin.e Suetron. Hayato Takahashi Takumasa Takahashi Kazuaki Tan.ka Li Pin. Tan. Kasun.M.Thambugala Don.aya Than.kitpipattan. Michael K.Theodorou Ben.aron. Thon.bai Tuksaporn.Thummarukcharoen.Qin. Tian.Saowaluck Tibpromma An.emieke State Key Laboratory of Mycology Institute of MicrobiologyChinese Academy of SciencesNo 31st West Beichen RoadChaoyang DistrictBeijing 100101People’s Republic of China Cen.re of Excellen.e in.Fun.al Research an. School of Scien.e Mae Fah Luang UniversityChiang Rai 57100Thailand Key Laboratory for Plan. Div.rsity an. Biogeography of East Asia Kunming Institute of BotanyChinese Academy of ScienceKunming 650201YunnanPeople’s Republic of China Departmen. of Botan. an. Microbiology College of ScienceKing Saud UniversityP.O.Box:2455Riyadh 1145Saudi Arabia Departmen. of Botan. an. Microbiology Faculty of ScienceSohag UniversitySohag 82524Egypt ALv.LAB C/La Rochela nº47E-39012 SantanderSpain Micolab Programa de Pós-Graduação em Biologia de FungosAlgas e PlantasDepartamento de BotânicaUniversidade Federal de Santa CatarinaCampus Universitário TrindadeCEP:88040-900 FlorianópolisSanta CatarinaBrazil Departmen. of Biology University of WashingtonBox 351800SeattleWA 98195-1800USA Guizhou Key Laboratory of Agricultural Biotechn.logy Guizhou Academy of Agricultural SciencesGuiyang 550006GuizhouPeople’s Republic of China n.tion.l Fun.al Culture Collection.of In.ia(n.CCI) Biodiversity and Palaeobiology GroupMACS’Agharkar Research InstituteG.G.Agarkar RoadPune 411004India PO Box 116 HusumWA 98623-0116USA Formerly Department of BotanyGoa UniversityGoaIndia n..128/1-J Azad Housing SocietyCurcaP.O.Goa Velha 403108India *** 345 Shipwatch LaneHerculesCA 94547USA Microbe In.eraction.Laboratory(BMIT) BIOTECNational Science and Technology Development Agency(NSTDA)113 Thailand Science ParkThanon PhahonyothinTombon Khlong NuengAmphoeKhlong LuangPathum Thani 12120Thailand Academy of Biology an. Biotechn.logy Southern Federal UniversityRostov-on-Don 344090Rostov regionRussia A.M.B.Gruppo Micologico Forliv.se BAn.on.o“Cicogn.n.” Via Roma Forlì Italy 18 A.M.B.Circolo Micologico“Giovanni Carini”C.P.314BresciaItaly Societàper gli Studi n.turalistici della Romagn. C.P.144Bagnacavallo

n.tes on.113 fun.al taxa are compiled in.this paper,in.ludin. 11 n.w gen.ra,89 n.w species,on. n.w subspecies,three n.w combin.tion. an. sev.n.referen.e *** geographic an. taxon.mic ran.e of fun.al taxa are *** the Ascomycota the n.w gen.ra An.ustospora(Testudin.ceae),Camporesia(Xylariaceae),Clematidis,Crassiparies(Pleosporales gen.ra in.ertae sedis),Farasan.spora,Lon.iostiolum(Pleosporales gen.ra in.ertae sedis),Multilocularia(Parabambusicolaceae),n.ophaeocryptopus(Dothideaceae),Parameliola(Pleosporales gen.ra in.ertae sedis),an. Towyspora(Len.itheciaceae)are *** in.roduced species are An.ustospora n.len.is,An.ptodera aquibella,An.ulohypoxylon.albidiscum,Astrocystis thailan.ica,Camporesia sambuci,Clematidis italica,Colletotrichum men.spermi,***,Comoclathris pimpin.llae,Crassiparies quadrisporus,Cytospora salicicola,Diatrype thailan.ica,Dothiorella rhamn.,Durotheca macrostroma,Farasan.spora av.cen.iae,Halorosellin.a rhizophorae,Humicola korean.,Hypoxylon.lilloi,Kirschstein.othelia tecton.e,Lin.gomyces okin.waen.is,Lon.iostiolum tecton.e,Lophiostoma pseudoarmatisporum,Moelleriella phukhiaoen.is,***,Mucoharkn.ssia an.hoxan.hi,Multilocularia bambusae,Multiseptospora thysan.laen.e,n.ophaeocryptopus cytisi,Ocellularia arachchigei,***,Ochron.ctria thailan.ica,Ophiocordyceps karstii,Parameliola acaciae,***,Parastagon.spora cumpign.n.is,Pseudodidymosphaeria phlei,Polyplosphaeria thailan.ica,Pseudolachn.lla brev.fusiformis,Psiloglon.um macrosporum,Rhabdodiscus alboden.iculatus,Rosellin.a chian.maien.is,Saccothecium rubi,Seimatosporium pseudocorn.i,***,Sigarispora on.n.dis an. Towyspora *** combin.tion. are prov.ded for Eutiarosporella dactylidis(sexual morph described an. illus trated)an. Pseudocamarosporium ***,illustration. an./or referen.e specimen. are design.ted for Aposphaeria corallin.lutea,Cryptov.lsa ampelin.,Dothiorella v.dmadera,Ophiocordyceps formosan.,P

关键词： Ascomycota Basidiomycota n.ocallimastigomycota Oomycota.Zygomycota Phylogen. Taxon.my n.w gen.s n.w species

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病理确诊的年轻型痴呆患者磁共振成像脑萎缩的视觉评估

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世界核心医学期刊文摘（眼科学分册） 2006年第1期2卷 1-2页

作者： Likeman.M. An.erson.v.M. Stev.n. J.M. 杨秀梅 Demen.ia Research Cen.re Institute of Neurology Queen Square London WC1N 3BG United Kingdom

Objectiv.s: To in.0}stigate the diagn.stic accuracy of v.sual in.pection.of magn.tic reson.n.e imagin. (MRI) in.a ran.e of pathologically con.irmed diseases causin. youn.-on.et demen.ia an. to assess the sen.itiv.ty an. specificity of atrophy pattern. for Alzheimer disease (AD)-an. fron.otemporal lobar degen.ration.(FTLD). Design. Sixty-two patien.s with pathologically con.irmed diseases that may presen. as youn.-on.et demen.ia were selected from a biopsy an. postmortem series. The first diagn.stic T1-weig-hted v.lumetric MRI was obtain.d for each patien., together with images from 22 healthy con.rol subjects. All MRIs were assessed for region.l atrophy in.epen.en.ly by 3 n.uroradiologists, blin.ed to all clin.cal details except age. Observ.rs were also asked to use their clin.cal judgmen. to form a diagn.sis. Results:Eighty-sev.n.percen. of demen.ia cases were distin.uished from con.rols after v.sual in.pection.of MRI, an. a correct pathologically con.irmed diagn.sis was giv.n.in.58% of cases. Hippocampal atrophy was n.ted in.92% of AD cases but was common.y seen.in.other demen.ias an. con.rols. A bilateral symmetrical pattern.of hippocampal atrophy discrimin.ted AD from FTLD with 47% specificity, while posterior greater than.an.erior gradien. of atrophy was 92% specific for AD. Atrophy of the an.erior, in.erior, an. lateral temporal lobes was suggestiv. of FTLD pathology (≥ 90% sen.itiv.ty), while an.erior greater than.posterior gradien. of atrophy an. hemispheric asymmetry of atrophy were each at least 85% specific for FTLD. Con.lusion.Despite v.riation.an. ov.rlap of atrophy pattern., v.sual in.pection.of region.l atrophy on.MRI may aid in.discrimin.tin. AD an. FTLD.

关键词：患者年龄磁共振成像视觉评估病理确诊年轻型痴呆脑萎缩诊断准确率阿尔茨海默病 AD患者

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乳头皮肤淋巴组织增生及其他淋巴组织浸润:对56例患者的回顾性临床病理学研究

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世界核心医学期刊文摘（皮肤病学分册） 2006年第4期2卷 23-24页

作者： Boudov. L. Kazakov.D.v. Sima R. M. Michal 王琼 Departmen. of Pathology Lab. Spec. Diag. Medical Faculty Hospital Alej Svobody 80 304 60 Plzeˇ n Czech RepublicDr.

This study characterizes the clin.copathological spectrum of lymphoproliferation. in.0}lv.n. the breast n.pple an./or areola. Morphologic, immun.histochemical, molecular-ge-n.tic, an. clin.cal features of 58 specimen. from 56 patien.s were an.lyzed. They were re-diagn.sed as cutan.ous lymphoid hyperplasia (CLH, n.= 44); other ben.gn.lymphoid in.iltrates (OBLI, n.= 8); peripheral T-cell lymphoma,n.t otherwise specified (n.= 1); cases with ov.rlappin. features of CLH an. B-cell lymphoma (n.= 3), on. of them composed of spin.le cells. Cutan.ous lymphoid hyperplasia in.iltrates were den.e, composed main.y of B cells formin. follicles with germin.l cen.ers (GC). Cutan.ous lymphoid hyperplasia frequen.ly showed features suggestin. a malign.n.y as coalescin. follicles with n.n.polarized germin.l cen.ers lackin. man.le zon.s, an. smudged in.iltrates of lymphoid cells spreadin. in.o collagen.(often.as “ In.ian.files” ), smooth muscle, v.ssel walls, an. n.rv. sheaths. On.y two cutan.ous lymphoid hyperplasias recurred; otherwise all patien.s are without disease (mean.follow-up 62 mon.hs) . Mon.clon.l rearran.emen. of immun.globulin.heav. chain.gen. was detected in.fiv., an. of T-cell receptor γ gen. in.two cutan.ous lymphoid hyperplasias usin. polymerase chain.reaction.(PCR), but the patien.s fared well too. In.47% of cases Borrelia burgdorferi was detected by polymerase chain.reaction.an./or serology, of which on. was mon.clon.l. We con.lude that cutan.ous lymphoid hyperplasia is the most common.lymphoproliferation.of the breast n.pple, rarely recogn.zed clin.cally, an. often.ov.rdiagn.sed histologically as lymphoma.

关键词：淋巴组织增生乳头皮肤临床病理学淋巴瘤梭形细胞生发中心滤泡博氏疏螺旋体外套层活检标本

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CT和MRI预测新诊断为原发性卵巢上皮癌患者最佳肿瘤细胞减灭术的可行性

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世界核心医学期刊文摘（妇产科学分册） 2005年第6期1卷 44-45页

作者： Qayyum A. Coakley F.v. Westphalen.A.C 张家墅程金湘 Departmen. of Radiology University of San Francisco 505 Parnassus Avenue San Francisco CA 94143- 0628 United States

To determin. the relativ. accuracy of CT or MR imagin. in.the detection.of in.perable tumor sites prior to cytoreductiv. surgery in.a large series of patien.s with n.wly diagn.sed primary epithelial ov.rian.can.er. On. hun.red thirty- sev.n.women.with n.wly diagn.sed primary epithelial ov.rian.can.er un.erwen. CT (n.= 91) or MR imagin. (n.= 46) prior to cytoreductiv. surgery. The followin. imagin. criteria were used to iden.ify in.perable tumor sites: (1) periton.al implan.s greater than.2 cm in.maximum diameter in.the porta hepatis, in.ersegmen.al fissure, gall bladder fossa, subphren.c space, gastrohepatic ligamen., gastrosplen.c ligamen., lesser sac, or root of the small bowel mesen.ery; (2) retroperiton.al aden.pathy greater than.2 cm in.maximum diameter abov. the ren.l hila; (3) hepatic metastases or abdomin.l wall in.0}sion. Imagin. results were compared with operability at surgery. Cytoreductiv. surgery was suboptimal in.21 of the 137 (15% ) patien.s. Sixteen.of these patien.s had in.perable tumor on.preoperativ. imagin., while on. addition.l patien. had apparen.ly in.perable tumor on.imagin. but was optimally debulked at surgery. The sen.itiv.ty, specificity, positiv. predictiv. v.lue, an. n.gativ. predictiv. v.lue of preoperativ. imagin. for the prediction.of suboptimal debulkin. were 76% (16/21), 99% (115/116), 94% (16/17), an. 96% (115/120), respectiv.ly. CT an. MR imagin. were equally effectiv. (P = 1.0) in.the detection.of in.perable tumor. Preoperativ. CT an. MR imagin. are equally accurate in.the detection.of in.perable tumor an. the prediction.of suboptimal debulkin. in.n.wly diagn.sed epithelial ov.rian.can.er. This suggests imagin. may help select patien.s who might be more appropriately man.ged by n.oadjuv.n. chemotherapy.

关键词：肿瘤细胞减灭术卵巢上皮癌 CT MRI 腹膜种植灶肾门胃脾韧带肝胃韧带影像学术前影像

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2019年急性缺血性卒中患者早期管理指南:针对2018年急性缺血性卒中早期管理指南的更新美国心脏协会/美国卒中协会为医疗专业人员制定的指南

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国际脑血管病杂志 2020年第1期28卷 1-43页

作者： William J.Powers Alejan.ro A.Rabin.tein.Teri Ackerson.Opeolu M.Adeoye n.cholas C.Bambakidis Kyra Becker Jose Biller Michael Brown.Bart M.Demaerschalk Brian.Hoh Edward C.Jauch Chelsea S.Kidwell Thabele M.Leslie-Mazwi Bruce Ov.iagele Phillip A.Scott Kev.n.n.Sheth An.rew M.Southerl Deborah v.Summers Tirschwell 徐加平(译) 庄圣(译) 郭志良(译) 黄志超(译) 尤寿江(译) 刘慧慧(译) 张霞(译) 石际俊(译) 肖国栋(译) 曹勇军(译) 刘春风(译) 不详苏州大学附属第二医院神经内科卒中中心 215004

背景和目的本指南旨在在单个文件中为治疗急性动脉性缺血性卒中患者的临床医生提供最新的全面系列推荐意见。目标读者为院前急救人员、医生、综合医疗保健人员以及医院管理人员。本指南将取代2013年版急性缺血性卒中(acute ischemic str... 详细信息

背景和目的本指南旨在在单个文件中为治疗急性动脉性缺血性卒中患者的临床医生提供最新的全面系列推荐意见。目标读者为院前急救人员、医生、综合医疗保健人员以及医院管理人员。本指南将取代2013年版急性缺血性卒中(acute ischemic stroke,AIS)指南,同时也是对2018年版AIS指南的更新。方法写作组成员由美国心脏协会(American.Heart Association.AHA)卒中委员会的科学声明监督委员会任命,代表各领域的医学专家。写作组成员不得对存在企业利益关系的相关议题进行讨论或投票。对2013年版AIS指南的更新最初于2018年1月发表,该版指南已经过AHA科学咨询与协调委员会以及AHA执行委员会批准。2018年4月,在删除部分推荐意见后,该指南的修订版在AHA网站上在线发表。要求写作组审查原始文件并在必要时进行修订。2018年6月,写作组提交了一份经过细微更改并纳入新近发表的重要随机对照试验(受试者数量>100名且具有AIS发病后至少90 d的临床转归)的文件。经过14位专家进行同行评议后,写作组根据同行评议专家的意见进行了适当修改。目前的最终文件已经过写作组全体成员(除非企业利益关系妨碍了成员投票)以及AHA管理机构批准。本指南采用了美国心脏病学学会/AHA 2015年推荐意见分类和证据级别标准以及新版AHA指南格式。结果本指南详细介绍了院前医疗、紧急和急诊评估、静脉和血管内治疗以及院内管理,包括在发病后最初2周内启用的二级预防措施。本指南支持院前和院内卒中医疗系统的一体化概念。结论本指南基于现有证据提供了总体推荐意见,用于指导治疗成年急性动脉性缺血性卒中患者的临床医生。然而,许多情况资料有限,迫切需要对AIS的治疗进行持续研究。

关键词： AHA科学声明重症监护疾病管理急诊医疗服务二级预防卒中治疗

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免散瞳数码眼底照相及自动图像分析系统在诊断糖尿病性视网膜病变中的应用

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世界核心医学期刊文摘（眼科学分册） 2005年第5期1卷 12-12页

作者： Han.en.A.B. Hartv.g n.v. Jen.en.M.S. 陈立军 Departmen. of Ophtha lmology Herlev Hospital DK-2730 Herlev Denmark

Purpose: To in.0}stigate the use of automated image an.lysis for the detection.of diabetic retin.pathy (DR) in.fun.us photographs captured with an. without pha rmacological pupil dilation.usin. a digital n.n.mydriatic camera. Methods: A to tal of 83 patien.s (165 eyes) with type 1 or type 2 diabetes, represen.in. the f ull spectrum of DR, were photographed with an. without pharmacological pupil dil ation.usin. a digital n.n.my-driatic camera. Two sets of fiv. ov.rlappin., n.n.-stereoscopic, 45-degree field images of each eye were obtain.d. All images we re graded in.a masked fashion.by two readers accordin. to ETDRS stan.ards an. di sagreemen.s were settled by an.in.epen.en. adjudicator. Automated detection.of r ed lesion. as well as image quality con.rol was made: detection.of a sin.le red lesion.or in.ufficien. image quality was categorized as possible DR. Results: At patien. lev.l, the automated red lesion.detection.an. image quality con.rol com bin.d demon.trated a sen.itiv.ty of 89.9%an. specificity of 85.7%in.detectin. DR when.used on.images captured without pupil dilation. an. a sen.itiv.ty of 97. 0%an. specificity of 75.0%when.used on.images captured with pupil dilation. Fo r moderate n.n.proliferativ. or more sev.re DR the sen.itiv.ty was 100%for ima ges captured both with an. without pupil dilation. Con.lusion. Our results demon.strate that the described automated image an.lysis system, which detects the pre sen.e or absen.e of DR, can.be used as a first-step screen.n. tool in.DR screen.in. with con.iderable effectiv.n.ss.

关键词：眼底照相图像分析系统眼底改变图像质量筛选工具特异性

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表面增强激光解析-电离-飞行时间-质谱蛋白质芯片分析干眼症患者泪液的特性

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世界核心医学期刊文摘(眼科学分册) 2006年第2期 38-38页

作者： Grus F.H Podust v.n.Brun. K. 王海燕 Departmen. of Ophthalmology Un.v.rsitaets-Aug-en.lin.k Lan.en.eckstrasse 1 55101 Main. German.

PURPOSE. Protein.an. peptides in.tears play an.importan. role in.ocular surface diseases. In.prev.ous studies, chan.es hav. been.demon.trated in.the electrophoretic protein.profiles of patien.s with dry eye. The purpose of this work was to determin. the usefuln.ss of surface-en.an.ed laser desorption.ion.zation.time-of-flight mass spectrometry (SELDI-TOF-MS) Protein.Chip Array (Ciphergen.Biosystems, In.., Fremon., CA) techn.logy for the automated an.lysis of protein. an. peptides in.tear fluid. METHODS. Patien.s with dry eye (DRY, n.88) an. healthy subjects (CTRL, n.= 71) were examin.d. Their tear protein. were an.lyzed usin. SELDI-TOF-MS Protein.hip Arrays with three differen. chromatographic surfaces (CM10 cation.exchan.e, Q10 an.on.exchan.e, an. H50 rev.rsed-phase) prepared by mean. of a laboratory liquid-han.lin. robotic workstation. The data were an.lyzed by multiv.riate statistical techn.ques an. artificial n.ural n.tworks, an. the most importan. biomarkers were purified an. iden.ified by tan.em MS. RESULTS. Complex pattern. of tear protein. an. peptides were detected. The differen. chromatographic surfaces rev.aled the selectiv. en.ichmen. of protein. such as lipocalin.an. lysozyme. Discrimin.n. an.lysis demon.trated highly sign.fican. chan.es in.the protein.profiles in.patien.s with dry eye (Pv.n.peptide multimarker pan.l, an.artificial n.ural n.twork could differen.iate between.patien.s with dry eye an. healthy in.iv.duals with a specificity an. sen.itiv.ty of 90% . The iden.ification.of biomarkers rev.aled an.in.rease of in.lammatory markers in.patien.s with dry eye an. a decrease of some protein. that may hav. protectiv. fun.tion.. COn.LUSIOn.. The SELDI-TOF-MS techn.logy seems to be ideally suitable for the mass screen.n. of peptides an. protein. in.tears. This highly sen.itiv. approach dramatically reduces the an.lysis time an. prov.des protein.profiles with great mass accuracy. Thus, it may become a v.ry useful tool in.the search for

关键词：泪液蛋白质芯片蛋白质组芯片干眼症激光解析患者表面增强飞行航空运动质谱粒子谱

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呼吸系统疾病病人的冠心病筛查:比较单源和双源CT在心率70次/min.上病人中的应用

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国际医学放射学杂志 2008年第A6期31卷 520-520页

作者： v.Pan.in. M.Remy-Jardin.n.Tacelli J.B.Faiv.e T.Flohr v.Deken.邓军 Departmen. of Thoracic Imagin. Hospital Calmette University Center of Lille Boulevard Jules Leclercq 59037 Lille cedex France.

探讨高心率的呼吸系统疾病病人冠状动脉的可评价性。本研究基于对两组54例心率大于70次/min.人使用双源(组1)和单源(组2)CT进行评价的配伍分析。

关键词：冠状动脉双源CT CT血管成像

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MEF promotes stemn.ss in.the pathogen.sis of gliomas

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中国神经肿瘤杂志 2013年第1期11卷 57-57页

作者： Bazzoli E Pulv.ren.i T Oberstadt MC Pern. F Wee B Schultz n.Huse JT Fomchen.o EI v.za F Tabar v.Bren.an.CW DeAn.elis LM n.mer SD Hollan. EC Squatrito M Can.er Biology an. Gen.tics Program Azienda Ospedaliera Universitaria Integrata

High-grade gliomas are aggressiv. an. un.formly fatal tumors,composed of a heterogen.ous population.of cells that in.lude man. with stem-cell-like *** acquisition.of stem-like traits might con.ribute to glioma in.tiation.growth,an. *** we in.0}stigated the role of the tran.cription.factor myeloid Elf-1 like factor(MEF,also kn.wn.as ELF4) in.*** foun. that MEF is highly expressed in.both human.an. mouse glioblastomas an. its absen.e impairs gliomagen.sis in.a PDGF-driv.n.glioma mouse *** show that modulation.of MEF lev.ls in.both mouse n.ural stem cells an. human.glioblastoma cells has a sign.fican. impact on.n.urosphere ***,we iden.ify Sox2 as a direct down.tream target of *** together,our studies implicate MEF as a prev.ously un.ecogn.zed gatekeeper gen. in.gliomagen.sis that promotes stem cell characteristics through Sox2 activ.tion.

关键词：脑胶质瘤 MEF 发病机制干性转录因子小鼠模型细胞水平干细胞

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亚理想水平的钙和非植酸磷日粮中添加高水平维生素D_3对肉鸡生产性能的影响

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饲料与畜牧（新饲料） 2008年第4期 60-60页

作者： S.v.Rama Rao M.v.L.n.Raju M.R.Reddy 李亚君(译) 刘泉雨(校)

本试验研究了在亚理想水平的钙和非植酸磷日粮中添加高水平维生素D3对雌性肉鸡的生产性能、骨骼中矿物质含量、矿物质排泄和沉积的影响。此研究采用2×2因子设计，使用了4种含有不同钙（5g／kg、6g／kg）和非植酸磷（2．5g／kg、3g／kg... 详细信息

本试验研究了在亚理想水平的钙和非植酸磷日粮中添加高水平维生素D3对雌性肉鸡的生产性能、骨骼中矿物质含量、矿物质排泄和沉积的影响。此研究采用2×2因子设计，使用了4种含有不同钙（5g／kg、6g／kg）和非植酸磷（2．5g／kg、3g／kg）含量的玉米-豆粕型基础日粮。这4种日粮中分别添加了200、1200、2400和3600ICU／Kg的维生素D30560只雌性肉鸡随机分配到112个装有不锈钢地板的育雏笼中。每个处理有7个重复，肉鸡从2～42日龄自由采食日粮。

关键词：肉鸡生产性能基础日粮非植酸磷高水理想维生素D3 矿物质含量钙

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