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Mathematical model of zika virus dynamics with vector control and sensitivity analysis

Infectious Disease Modelling 2020年第1期5卷 23-41页

作者： Sudhanshu Kumar Biswas uttam ghosh Susmita Sarkar Department of Mathematics Sripat Singh CollegeMurshidabadWest BengalIndia Department of Applied Mathematics University of CalcuttaKolkataIndia

In this paper,we have developed and analyzed a deterministic Zika model considering both vector and sexual transmission route with the effect of human awareness and vector control in the absence of disease induce *** formulate the model,we assume that the Zika virus is being first transmitted to human by mosquito bite,and then it is being transmitted to his or her sexual *** system contains at most three equilibrium points among them one is the disease free and other two are endemic equilibrium points,exists under certain *** theoretical analysis shows that the diseases-free equilibrium is locally and globally asymptotically stable if the basic reproduction number is less than *** we have established that endemic equilibrium point which is locally asymptotically stable if the basic reproduction number is greater than *** system exhibits backward bifurcation when the transmission probability per biting of susceptible mosquito with infected humans crosses the critical *** estimate the model parameters and validate the model by fitting the model with the reported Zika infected human data from 1 to 36 week of 2016 Zika outbreak in ***,using the normalised forward sensitivity index method we have established that the model parameter mosquito biting rate,recruitment rate of mosquito,transmission probability per biting of Susceptible(infected)humans with infected(susceptible)mosquito,rate of awareness in host population,recovery rates of infected human are most sensitive parameters of the considered Zika ***,some conclusions are given to control the spreading of the Zika disease.

关键词： Zika virus Vector transmission Sexual transmission Basic reproduction number Stability analysis Backward bifurcation Sensitivity analysis

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Minimization of Phenols and Phenolic Compounds in Pulp and Paper Industries： Biological Approaches

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Journal of Chemistry and Chemical Engineering 2011年第7期5卷 595-607页

作者： Manoj Kumar ghosh uttam Kumar ghosh Samit Kumar Department of Paper Technology Indian Institute of Technology Roorkee Saharanpur Campus Saharanpur 247001 U.P. India

The liquid effluents released from several industries including the pulp and paper industries contain phenol and phenolic compounds. The hazardous phenols and their chlorinated phenolic derivatives from pulp and paper industries bear the potential to exert deleterious effects on the human health and aquatic ecosystems, if they are released untreated in the environment. Biodegradation of phenolic compounds in the effluent streams from pulp and paper industries is an important eco-friendly method for the removal of toxicity in industrial waste water, while the minimization of formation of these toxic compounds require several in-plant biotechnological techniques such as biopulping and biobleaching. Present paper reviews, the biochemical pathways involved in degradation of phenols and chlorophenols through microorganisms. Various biotechnological strategies involved in minimization and biodegradation of phenol and phenolic compounds and their related environmental engineering aspects such as utility of different bioreactor configurations have been discussed for the treatment of pulp and paper mill effluents.

关键词： Biodegradation biobleaching biopulping chlorophenol.

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Fractional Weierstrass Function by Application of Jumarie Fractional Trigonometric Functions and Its Analysis

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Advances in Pure Mathematics 2015年第12期5卷 717-732页

作者： uttam ghosh Susmita Sarkar Shantanu Das Department of Mathematics Nabadwip Vidyasagar CollegeNabadwipIndia Department of Applied Mathematics University of CalcuttaKolkataIndia Reactor Control Systems Design Section E&I GroupBARCMumbaiIndia

The classical example of no-where differentiable but everywhere continuous function is Weierstrass function. In this paper we have defined fractional order Weierstrass function in terms of Jumarie fractional trigonometric functions. The H?lder exponent and Box dimension of this new function have been evaluated here. It has been established that the values of H?lder exponent and Box dimension of this fractional order Weierstrass function are the same as in the original Weierstrass function. This new development in generalizing the classical Weierstrass function by use of fractional trigonometric function analysis and fractional derivative of fractional Weierstrass function by Jumarie fractional derivative, establishes that roughness indices are invariant to this generalization.

关键词： Holder Exponent Fractional Weierstrass Function Box Dimension Jumarie Fractional Derivative Jumarie Fractional Trigonometric Function

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Yield Response of Direct Seeded <i>Aus</i>Rice Varieties under Rainfed Condition

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American Journal of Plant Sciences 2018年第3期9卷 416-434页

作者： uttam Kumar ghosh Md. Arifur Rahman Khan M Abdul Karim Md Anamul Haque Department of Agronomy Bangabandhu Sheikh Mujibur Rahman Agricultural University Gazipur Bangladesh

Rainfed Aus rice is a popular conventional rice cultivation technique that through appropriate variety selection can accelerate the benefits of the farmer. On this context, an experiment was carried out at the research field of Bangabandhu Sheikh Mujibur Rahman Agricultural University, Gazipur1706 from April to August in 2014 to evaluate yield performance of some Aus rice varieties under rainfed condition. The experiment was laid out in a split plot design with three replications. The experiment consisted of two sets of treatments: water regime as irrigated (irrigation when necessary) and rainfed (dependent on rainfall) in the main plot and 15 varieties into sub-plots. It was revealed that yield and yield contributing characters were significantly influenced by water regime, variety and their interaction. The traits like number of effective tillers and non-effective tillers·hill-1, number of filled grains and unfilled grains panicle-1, panicle length, test weight, grain yield and harvest index were higher in irrigated crops compared to rainfed. Considering the performance of yield, the highest grain yield recorded in BRRI dhan27 (irrigated-2.47 t·ha-1 and rainfed-2.26 t·ha-1) followed by BRRI dhan55 (irrigated-1.95 t·ha-1 and rainfed-1.88 t·ha-1), BRRI dhan48 and BRRI dhan43 under both irrigated and rainfed treatment. BRRI dhan27 ranked the top under both irrigated and rainfed conditions, however the relative yield was maximum in BRRI dhan55 (reduction was only 3.59%) followed by Nerica10. Hence, considering the yield stability and absolute yield performance, BRRI dhan27 may be considered favorably cultivable for Aus season in Bangladesh followed by BRRI dhan55, BRRI dhan48 and BRRI dhan43.

关键词： Irrigation Rice Varietal Performance Nerica Relative Yield

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COVID-19 therapeutics:Clinical application of repurposed drugs and futuristic strategies for target-based drug discovery

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Genes & Diseases 2023年第4期10卷 1402-1428页

作者： Sunny Kumar Malini Basu Pratyasha ghosh uttam Pal Mrinal K.ghosh Cancer Biology and Inflammatory Disorder Division Council of Scientific and Industrial Research-Indian Institute of Chemical Biology(CSIR-IICB)TRUE CampusCN-6SectoreVSalt LakeKolkata-700091&4Raja S.C.Mullick RoadJadavpurKolkata 700032India Department of Microbiology Dhruba Chand Halder CollegeDakshin BarasatWest Bengal 743372India Department of Economics Bethune CollegeUniversity of CalcuttaKolkata 700006India

Severe acute respiratory syndrome coronavirus-2(SARS-CoV-2)causes the compli-cated disease *** are continuously facing huge problems in the treatment of patients,as COVID-19-specific drugs are not available,hence the principle of drug repurpos-ing serves as a one-and-only ***,the repurposing of many drugs is underway;few of them are already approved by the regulatory bodies for their clinical use and most of them are in different phases of clinical *** in this review,our main aim is to discuss in detail the up-to-date information on the target-based pharmacological classification of repurposed drugs,the potential mechanism of actions,and the current clinical trial status of various drugs which are under repurposing since early *** last,we briefly proposed the probable phar-macological and therapeutic drug targets that may be preferred as a futuristic drug discovery approach in the development of effective medicines.

关键词： Clinical trials COVID-19 Drug discovery Pharmacology Repurposing of drugs SARS-CoV-2

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Dual-wavelength all-fiber Q-switched fiber laser using bismuth-doped fiber as saturable absorber

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Optoelectronics Letters 2024年第3期20卷 147-151页

作者： Aruna ghosh Abdulkadir Mukhtar Diblawe uttam Kumar Samanta Moh Yasin Sulaiman Wadi Harun Mukul Chandra Paul Fiber Optics and Photonics Division CSIR-Central Glass and Ceramic Research InstituteKolkata 700032India Physics Department Jadavpur UniversityKolkata 700032India Photonics Engineering Laboratory Department of Electrical EngineeringUniversity of MalayaKuala Lumpur 50603Malaysia Department of Physics Faculty of Science and TechnologyAirlangga UniversitySurabayaIndonesia

A passively Q-switched all-fiber laser is demonstrated using a 10-cm-long bismuth-doped fiber(BDF) as a saturable absorber(SA). The dual-wavelength operation was obtained due to the nonlinear effect inside the fabricated BDF, which has a high germanium content. Stable Q-switched pulses were obtained at the dual synchronous wavelengths of 1 530.1 nm and 1 531.1 nm. When the pump power is tuned from 105.3 mW to 191.0 mW, the repetition rate can be varied from 82.6 kMz to 117.6 kHz. The maximum pulse energy and average output power were 83.4 nJ and 9.8 mW, respectively while the minimum pulse width was 8.5 μs at the maximum pump power of 191.0 mW. Our results indicate that BDF could be a promising alternative optical modulator for pulsed fiber laser application.

关键词： fiber switched pump

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The Effects of Omega-3 Fatty Acids Supplementation in Bronchial Asthma

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Journal of Biosciences and Medicines 2023年第4期11卷 208-219页

作者： uttam Kumar Barua Pranab Karmaker Arup Kumar Saha Md. Merazul Mostofa Dilip Kumar ghosh Kamal Krishna Biswas Department of Respiratory Medicine Shaheed Suhrawardy Medical College Hospital Dhaka Bangladesh Bangladesh Reference Institute for Chemical Measurements (BRiCM) Dhaka Bangladesh Department of Dental Public Health City Dental College and Hospital Dhaka Bangladesh Department of Genetic Engineering and Biotechnology University of Rajshahi Rajshahi Bangladesh Department of Gastroenterology Shaheed Suhrawardy Medical College Hospital Dhaka Bangladesh Department of Biochemistry and Molecular Biology University of Rajshahi Rajshahi Bangladesh

Bronchial asthma is a chronic inflammatory disease. Allergies are intensely related to bronchial asthma and to other respiratory diseases such as chronic sinusitis, middle ear infections, and nasal polyps. Treatment can vary from inhalers to oral medications to drugs delivered in a nebulizer or breathing machine. Besides, dietary involvement was a significant tool to reduce the severity of many chronic inflammatory diseases including asthma. Randomly assigned, double blind, and placebo controlled 290 adults with mild to moderately persistent bronchial asthma concluded in this study, were subjected to alternating phases of supplementation with omega-3 fatty acids, vitamin C and Zn either singly or in combination. Subjective symptom improvement, pulmonary function, and biochemical tests were carried out at the beginning of the study and at the end of each therapeutic phase. The study findings showed that nearly half of the cases were in age between 18 years to 40 years followed by 29.6 of the cases that fall in age range between 40 years and 60 years. It was clear that all the four supplements (ogema-3 fatty acids, vitamin C and Zn, and combination) contributed more than placebo in reducing the severity of bronchial asthma. However, omega 3 fatty acids and combined supplement significantly contributed in symptomatic improvement (p < 0.05). There was a significant improvement of pulmonary function and sputum inflammatory markers with diet supplementation (p < 0.05). So, the subjects with mild and moderately persistent bronchial asthma may get benefit from their dietary supplementation with omega 3 fatty acids, Zinc and vitamin C. It is evident from this study that omega 3 fatty acids and combined supplementation significantly improved the severity of bronchial asthma.

关键词： Bronchial Asthma FEV1 FVC Omega 3 Fatty Acids

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