检索结果-南通市图书馆

Effectof Ginsenoside Re on Cardiomyocyte Apoptosis and Expression of Bcl-2/Bax Gene after Ischemia and Reperfusion in Rats

在线全文

学校读者我要写书评

暂无评论

Journal of huazhong University of Science and Technology(medical Sciences) 2002年第4期22卷 305-309页

作者：刘正湘李志刚刘晓春 DepartmentofCardiology DepartmentofNeurobiology

To observe the effectof ginsenoside Re on cardiomyocyte apoptosis and Bcl- 2 / Bax gene expression after ischemia (30 m in) and reperfusion (6 h) in rats and to elucidate the possible m echanism s of ginsenoside Re on inhibition of cardiom yocyte apoptosis,the ischem ia/ reperfusion heart m odel was established by ligating the left anterior descending branch of coronary artery in Wistar *** apoptotic cardiom yocytes were confirmed by transm ission electron m icroscopy and counted by in situ nick end labeling(TU NEL) method and lightm *** m RNA and protein expression of Bcl- 2 and Bax genes were studied by in situ hybridization and im munohis- tochemical *** optical density (od) value of the positive fields of m RNA and protein expression was quantitatively exam ined by im age analysis *** results were as follows: (1) The apoptotic cardiomyocytes were found in ischemic fields in the ischem ia/ reperfusion group and weren't observed in the sham- operation group by transmission electron microscopy;(2 ) The num bers of the apoptotic cells were134.4 5± 4 5 .6 1/ field in the ischemia/ reperfusion group,and 90 .6 6± 19.2 2 / field in the ginsenoside Re- treated *** differences was significant between two groups(Phe is- chemia/ reperfusion group and ginsenoside Re- treated group when compared with the sham - opera- tion *** was no significant difference in the gene expression of Bcl- 2 between the gin- senoside Re- treated group and ischemia/ reperfusion group(P>0 .0 5 ) ,but gene expression of Bax was decreased significantly in the ginsenoside Re- treated group as compared with the ischem ia/ reperfusion group(Phe ratio of Bcl- 2 / Bax was increased significantly in the ginseno- side Re- treated group when com pared with the ischem ia/ reperfusion group and sham- operation *** findings suggest that m yocardia

关键词： ginsenoside Re ischemia/ reperfusion cardiomyocyte apoptosis Bcl- 2 / Bax

在线全文

学校读者我要写书评

暂无评论

林带对春大麦产量的影响

江苏林业科技 1992年第S1期 61-64页

作者： h·m·米罗谢尔道夫 ,李晓储

关于防护林带下春大麦的产量,据报道在遭受干热风影响的1982年,赫尔松斯克省叶里萨韦特格拉斯茨县阿尔布琴斯克乡卡灭罗瓦特林带间农田的产量为1050kg/hm2,而空旷地的产量每公顷只有225～300kg。在风调雨顺的1902年,接近林缘的春大麦的... 详细信息

关于防护林带下春大麦的产量,据报道在遭受干热风影响的1982年,赫尔松斯克省叶里萨韦特格拉斯茨县阿尔布琴斯克乡卡灭罗瓦特林带间农田的产量为1050kg/hm2,而空旷地的产量每公顷只有225～300kg。在风调雨顺的1902年,接近林缘的春大麦的产量比调查地的中间地块少。在遭受干旱的1955年,在捷尔库斯林区的防护下,每公顷收获春大麦1890kg,即比每公顷空旷地超产350kg。甚至在大旱的1954年,据乌克兰南部林区的调查资料,林带内农地的产量每公顷也增加了200kg。 1962～1968年,在基洛沃格勒斯克省马罗维斯科夫斯克地区胜利国营农场,防护林带下春大麦每公顷收获2540kg,而紧靠着处于相同土壤气候条件的空旷地块每公顷少收

关键词：林带春大麦产量

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

早产儿成年后的动态血压及其变异

中华高血压杂志 2015年第3期23卷 299-299页

作者： Sipola-Lepp?nen m Karvonen R Tikanm?ki m matinolli hm martikainen S Pesonen AK R?ikk?nen K J?rvelin mR hovi P Eriksson JG V??r?sm?ki m Kajantie E 赵狄练桂丽

早产儿成年后血压高于足月产儿成年后的血压。许多研究针对早产,但很少研究评估作为心血管病独立危险因素的血压变异。该研究在42例孕早期（〈34周）早产青年成人,72例孕晚期（34～36周）早产及103例对照（≥37周）中探讨早产与24h动态... 详细信息

早产儿成年后血压高于足月产儿成年后的血压。许多研究针对早产,但很少研究评估作为心血管病独立危险因素的血压变异。该研究在42例孕早期（〈34周）早产青年成人,72例孕晚期（34～36周）早产及103例对照（≥37周）中探讨早产与24h动态血压的关系。72.4%的研究对象的睡眠经加速度传感器睡眠监测证实。

关键词： 24h动态血压血压变异早产儿成年独立危险因素加速度传感器睡眠监测心血管病

在线全文

学校读者我要写书评

暂无评论

林带对春大麦产量的影响

江苏林业科技 1992年第A10期19卷 61-64页

作者： h.m.米罗谢尔道夫李晓储

关于防护林带下春大麦的产量,据报道在遭受干热风影响的1982年,赫尔松斯克省叶里萨韦特格拉斯茨县阿尔布琴斯克乡卡灭罗瓦特林带间农田的产量为1050kg/hm^2,而空旷地的产量每公顷只有225～300kg。在风调雨顺的1902年,接近林缘的春大麦... 详细信息

关于防护林带下春大麦的产量,据报道在遭受干热风影响的1982年,赫尔松斯克省叶里萨韦特格拉斯茨县阿尔布琴斯克乡卡灭罗瓦特林带间农田的产量为1050kg/hm^2,而空旷地的产量每公顷只有225～300kg。在风调雨顺的1902年,接近林缘的春大麦的产量比调查地的中间地块少。在遭受干旱的1955年,在捷尔库斯林区的防护下,每公顷收获春大麦1890kg,即比每公顷空旷地超产350kg。甚至在大旱的1954年,据乌克兰南部林区的调查资料,林带内农地的产量每公顷也增加了200kg。 1962～1968年,在基洛沃格勒斯克省马罗维斯科夫斯克地区胜利国营农场,防护林带下春大麦每公顷收获2540kg。

关键词：春大麦产量林带

克罗恩病及结肠癌中大肠埃希菌的黏附性和侵袭性增加

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

世界核心医学期刊文摘（胃肠病学分册） 2005年第2期1卷 27-28页

作者： martin h.m. Campbell B.J. hart C.A. J.m. Rhodes 翟惠虹 Department of medicine Henry Wellcome Lab. Molec.Cell. G. Univ. of Liverpool United Kingdom Liverp oolUnited Kingdom

Background &Aims: Altered mucosal glycosylation in inflammatory bowel disease and colon cancer could affect mucosal bacterial adherence. This study aimed to quantify and characterize mucosa-associated and intramucosal bacteria,particula rly Escherichia coli, in these conditions. methods:mucosa-associated bacteria w ere isolated, after dithiothreitol mucolysis, from biopsy samples obtained at co lonoscopy(Crohn’s disease, n = 14 patients; ulcerative colitis, n = 21;noninfla med controls, n = 24) and at surgical resection (colon cancer, n = 21). Intramuc osal bacteria were grown after gentamicin treatment followed by hypotonic lysis. Results:mucosa-associated and intramucosal bacteria were cultured more commonl y in Crohn’s disease (79%, P = 0.03; and 71%,P han in noninflamed controls (42%and 29%) a nd were commonly cultured from colon cancers (71%and 57%). mucosa-associated E. coli, which accounted for 53%of isolates,were more common in Crohn’s diseas e (6/14; 43%) than in noninflamed controls (4/24, 17%), as also were intramuco sal E. coli: Crohn’s disease, 29%; controls, 9%. E. coli expressed hemaggluti nins in 39%of Crohn’s cases and 38%of cancers but only 4%of controls, and th is correlated (P = 0.01) with adherence to the I407 and hT29 cell lines. Invasio n was cell-line dependent. E. coli, including nonadherent isolates, induced int erleukin-8 release from the cell lines. E. coli adhesins showed no blood group specificity, excepting 1 cancer isolate (hm44)with specificity for the Thomsen- Friedenreich antigen, but they could be blocked by soluble plantain fiber. Concl usions: These studies support a central role for mucosally adherent bacteria in the pathogenesis of Crohn’s disease and colon cancer. Soluble plant fibers that inhibit their adherence have therapeutic potential.

关键词：克罗恩病大肠埃希菌侵袭性结肠癌黏附性溃疡性结肠炎炎症性肠病非炎症性结肠镜检红细胞凝集素

microvascular Changes in the Retrobulbar Optic Nerve in Idiopathic Intracranial hypertension

在线全文

学校读者我要写书评

暂无评论

眼科学报 1999年第1期15卷 7-12页

作者： Xinzu Gu, X.h. Lin, h.G. Saddati, Y.Zhong, h.Y.hsu, A.A.SadunZhongshan Ophthalmic Center, Sun Yat-sen University of medical Sciences, Guangzhou 510060 , China Department of Ophthalmology, USC School of medicine , Doheny Eye Institute, Los Angeles , CA 90033 Correspondence: Xinzu Gu, mD, PhD, Zhongshan Ophthalmic Center, Sun Yat-sen University of medical Sciences, 54 Xianlie Road, Guangzhou 510060, China Zhongshan Ophthalmic Center Sun Yat-sen University of Medical Sciences 54 Xianlie Road Guangzhou 510060 China

Purpose : To examine the microvascular changes in the retrobulbar optic nerve in idio-pathic intracranial hypertension (PTC).methods: Both optic nerves from a 29-year-old man with a two year history of PTC were examined histologically and morphometrically. A semi-automated image analysis system and paraphenylenediamine (PPD) stain were employed to resolve sufficiently the microvascular images for counts and ***: There were 150 vessels distributed in the optic nerves which revealed the following: The average lumen of the vessels in outer sectors were larger than those of the inner sector vessels (168. 17μm2vs. 46. 99μm2; p = 0. 0338;od; and 251. 96μm2vs. 130.02μm2;p = 0.029;OS) while in the normal control optic nerve the outer and inner area lumens were reversed in size-differential, but this did not show a statistical difference. The thickness of the PTC optic nerve vessel walls in the outer sectors was also greater than that of the walls in the inner sectors (4. 95μm vs. 2. 67μm;

关键词：神经微脉管轴突退化原发性颅骨内高血压

Contraceptive practice among postpartum urban women in Zibo city of Shandong province

在线全文

学校读者我要写书评

暂无评论

生殖医学杂志 2002年第Z1期11卷 65-70页

作者：张立英刘云嵘 Iqbal h.Shah National Research Institute for Family Planning Bei-jing 100081China Special Program of Research Development and Re-search Training in Human ReproductionDepartment of Re-productive Health ResearchWorld Health Organization

Objectives: The objective of this study was to investigate the existing pattern of contraceptive use among postpartum women in urban areas of ***: A hospital based longitudinal study was carried out in Z ibo city, Shandong province of China from June 1996 to November 1997. Both quant itative and qualitative research approaches were used. This report mainly deals with the quantitative data. Qualitative data provided insights into the behavior of breastfeeding and contraceptive use, which helped to understand the percepti ons and behavior of people and community in this area. Information was obtained from 496 new parturient women who gave birth in the five district hospitals wher e they first were interviewed. They were then followed-up three timings for int erview at 42 days, four months and one year after delivery, respectively. Struct ured interview questionnaires filled out by trained interviewers. Total subjects of 492 women were for analysis in this ***: The results showed that 74.4% of women were using contr aceptive methods when they resuming the first sexual activity after delivery. Du ring postpartum period, the majority of women interviewed used condom within 3 m onths, for instance, at 3 months after delivery, there were still 84.5% of women use condom. Afterwards, most of them switched to IUD. Life table analysis shows that the continuation rates of full breastfeeding, abstinence, amenorrhea and a cceptance of contraceptive methods at 4 months after delivery were 35.5%, 68.2%, 5.0%, and 86.3%, respectively. Conclusion: The policy implications of this study are that contr aceptive services and information for postpartum women in urban areas need to be improved further. The contraceptive methods providing for postpartum women shou ld have more methods to let women choose and instead of only one method for all of postpartum women.

关键词： Contraception Postpartum Breastfeeding

在线全文

学校读者我要写书评

暂无评论

金属硬掩膜打开工艺中的CD偏差负载控制

功能材料与器件学报 2013年第6期19卷 308-311,307页

作者： D.J.Wang m.D.hu J.Q.Zhou C.L.Zhang h.Y.Zhang X.P.Wang Semiconductor manufacturing International Corporation

本文系统地研究了密集线条和孤立线条间CD(关键尺寸)刻蚀偏差参数对金属硬掩膜(mhm)刻蚀工艺的影响,涉及的范围有化学气体、源功率、压力、偏差功率以及ESC温度。特别是,如果正确地应用基于Ch4的等离子固化光刻胶掩膜,发现它具有控制密... 详细信息

本文系统地研究了密集线条和孤立线条间CD(关键尺寸)刻蚀偏差参数对金属硬掩膜(mhm)刻蚀工艺的影响,涉及的范围有化学气体、源功率、压力、偏差功率以及ESC温度。特别是,如果正确地应用基于Ch4的等离子固化光刻胶掩膜,发现它具有控制密集和ISO CD负载的特殊能力,且同时保持准确的密集CD。而且,在基于Cl2和基于hBr的BARC打开步骤之间,还看到刻蚀化学气体对CD负载的有重大影响。此外,也发现m-hm的应力和刻蚀后剖面影响CD负载性能。根据这些发现,成功地展示了改善钨触点和铜沟槽之间电气互连的解决方法。

关键词：化学刻蚀负载控制沟槽偏差比较聚合物隔离负载效应线条刻蚀工艺掩膜

母亲接受倍他米松治疗对胎儿心率及其变异性的短期(0～48h)影响

在线全文

学校读者我要写书评

暂无评论

世界核心医学期刊文摘（儿科学分册） 2005年第8期1卷 58-59页

作者： Lunshof m.S. Boer K. Wolf h. 王经纬 Onze Lieve Vrouwe Gasthuis Dept. of Obstetrics and Gynecology P.O. Box 95500 1090 HM Amsterdam Netherlands

The short- term (0- 48 h) effects of maternal betamethasone administration on computerized fetal heart rate (FhR) parameters were studied in 36 pregnancies at increased risk for preterm delivery. FhR was recorded for 90 min immediately before the start of betamethasone treatment and again at 6- h intervals during the next 48 h. multiple linear regression models were used to assess the possib le effects on FhR parameters of gestational age, time of day, clinical indicatio n for treatment, and use of tocolytic drugs. Within 12 h after the start of trea tment, significant increases occurred in FhR accelerations, and short- and long - term FhR variability (36% , 28% , and 22% , respectively), whereas basal F hR showed a 5% decrease. FhR variability was decreased by 10% at 42- 48 h. The observed changes were more pronounced in older (29- 33 wk of gestation) compared with younger fetuses (25- 28 wk of gestation). Decelerations occurred only in 4 out of 11 compromised fetuses during betamethasone therapy. We conclude that there are significant changes in FhR parameters during the first 48 h after betamethas one administration. These changes are transient in normal fetuses. however, the compromised fetus may be adversely affected by betamethasone.

关键词：胎儿心率倍他米松正常胎儿模型评价变异率免疫缺乏基线水平