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Molecular Plant 2023年第5期16卷 919-929页

作者： umme Amara Jianzhong Hu Jing Cai Hunseung Kang Department of Applied Biology College of Agriculture and Life SciencesChonnam National UniversityGwangju 61186South Korea

n^(6)-methyladenosine(m^(6)A),which is added,removed,and interpreted by m^(6)A writers,erasers,and readers,respectively,is the most abundant modification in eukaryotic *** m^(6)A marks play a pivotal role in the regulation of floral transition in *** LOCUS K(FLK),an RnA-binding protein harboring K-homology(KH)motifs,is known to regulate floral transition by repressing the levels of a key floral repressor FLOWERInG LOCUS C(FLC)in ***,the molecular mechanism underlying FLK-mediated FLC regulation remains *** this study,we identified FLK as a novel mRnA m^(6)A reader protein that directly binds the m^(6)A site in the 3ʹ-untranslated region of FLC transcripts to repressing FLC levels by reducing its stability and ***,FLK binding of FLC transcripts was abolished in vir-1,an m^(6)A writer mutant,and the late-flowering phenotype of the flk mutant could not be rescued by genetic complementation using the mutant FLKm gene,in which the m^(6)A reader encoding function was eliminated,indicating that FLK binds and regulates FLC expression in an m^(6)A-dependent ***,our study has addressed a long-standing question of how FLK regulates FLC transcript levels and established a molecular link between the FLK-mediated recognition of m^(6)A modifications on FLC transcripts and floral transition in Arabidopsis.

关键词： Arabidopsis thaliana RnA methylation m^(6)A reader FLK floral transition FLC

Antihypertensive efficacy of extract of Hedera helix in high salt-induced hypertensive Sprague-Dawley rats

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Asian Pacific Journal of Tropical Medicine 2018年第8期11卷 473-479页

作者： umme Salma Taous Khan Abdul Jabbar Shah Cardiovascular Research Group Department of Pharmacy COMSATS University IslamabadAbbottabad campus

Objective: To explore the antihypertensive effect of extracts from the leaves of Hedera helix(H. helix) on normotensive and hypertensive rats in-vivo followed by vasodilatory studies ***: The crude methanolic extract was prepared and the activity directed fractionation was carried out. Spectrophotometric analysis of total phenolic and flavonoid content was also done. HPLC analysis was performed for the detection of hederacoside C. In-vivo blood pressure study was carried out in normotensive and high salt-induced hypertensive SpragueDawley rats. Isolated aortic tissues from rat and rabbit were used for in-vitro studies. The effects were recorded and analyzed through PowerL ab data acquisition system. Results: Crude extract of H. helix(1-30 mg/kg) decreased blood pressure to greater extent in high salt-induced hypertensive rats in-vivo compared to the normotensive [Max. fall(58.59±0.02) mm Hg vs.(67.53±3.07) mmH g]. The n-hexane, chloroform, ethyl acetate and aqueous fractions were also checked. These fractions were more effective in hypertensive rats. Aqueous fraction was more potent and n-hexane the least. In isolated rat aortic rings precontracted with phenylephrine, crude extract induced endothelium-dependent effect. The endothelium-dependent component of vasodilatory effect was ablated with L-nAME, and denudation of endothelium. The aqueous fraction was most potent vasodilator. In aortic rings from hypertensive rats, extract and fractions produced partial endothelium-independent effect which was not affected by pretreatment with L-nAME, indicating endothelium dysfunction in the hypertensive rats and suggesting additional vasodilatory mechanisms. In rabbit aorta, the extract and fractions also inhibited phenylephrine and high K^+-induced precontractions, and shifted Ca^(++) concentration–response curves. Conclusions: Our findings indicate that extract and fractions of H. helix are antihypertensive remedies, which is the outcome of vasodilatory effect.

关键词： Hedera helix Antihypertensive Vasorelaxant Endothelium-dependent nitric oxide Calcium channel blocker

On ideal convergence of double sequences in 2-fuzzy n-normed linear space

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Applied Mathematics(A Journal of Chinese Universities) 2022年第2期37卷 177-186页

作者： Vakeel A.Khan Sameera A.A.Abdullah Kamal M.A.S.Alshlool umme Tuba nazneen Khan Department of Mathematics Aligarh Muslim UniversityAligarh 202002India Department of Mathematics Sultan Qaboos UniversityMuscatOman

The purpose of this paper is to define the notions of convergence, Cauchy st–convergence, st–Cauchy, I –convergence and I –Cauchy for double sequences in 2–fuzzy n–normed spaces with respect to α–n–norms and ... 详细信息

关键词： 2-fuzzy n-normed spaces -n-norm I-convergence I-Cauchy

Predicting the effectiveness of protected areas of natura 2000 under climate change

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Ecological Processes 2019年第1期8卷 162-182页

作者： Mst.umme Salma nila Carl Beierkuhnlein Anja Jaeschke Samuel Hoffmann Md Lokman Hossain Global Change Ecology International Elite Study ProgrammeUniversity of BayreuthUniversitätsstraße 3095447 BayreuthGermany Department of Biogeography University of BayreuthUniversitätsstraße 3095447 BayreuthGermany Department of Geography Hong Kong Baptist University15 Baptist University RoadKowloon TongHong Kong Department of Environmental Protection Technology German University Bangladesh1702 GazipurBangladesh.

Background:Protected areas(PAs)are aimed to hold the environmental conditions that facilitate species and ecosystems to *** can become climatically unsuitable and unable to sustain their current number of species under climate *** natura 2000(n2K)is the largest coordinated conservation tool assigned to maintain the long-term survival of Europe’s most significant species and *** attempting to understand the effectiveness of PAs in the face of climate change scenarios,we tested two hypotheses:(1)PAs in the Alpine and the Boreal biogeographical regions will experience more newly emerged climate conditions(hotter and drier)compared to the climate representation of other biogeographical regions under future climate in Europe and(2)PAs in the Mediterranean and the Continental biogeographical regions will face more consistency in climate conditions due to less area of disappearing and novel climate in ***:Current climate data(1960–1990)and projections for 2050 and 2070 of PAs of n2K were extracted from WorldClim global climate *** components analysis(PCA)was performed to construct climate space for the PAs across the biogeographical regions based on 19 climatic variables assessed at 5-km *** 10.1 was used to map the location of the novel and disappearing ***:PAs in the Alpine region will experience more novel climate conditions in the future compared to other biogeographical *** future projections showed that 17.70%of the PAs in the Alpine region will experience novel climate by *** climate consistency was observed in the PAs in the Continental region compared to the other biogeographical *** results showed that about 176 km2 of the selected PAs in the Continental region will face new emerging climate,while about 110 km2 will disappear under RCP 8.5 *** prediction also revealed that in the Mediterranean region 08 PAs will experience novel climate and 786 km2 areas

关键词： Biodiversity conservation Biogeographical region Climate change Climate scenarios natura 2000,Protected areas

Effect of Missing nutrient Elements on Grain Yield of Wet Season Rice in Bangladesh

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American Journal of Plant Sciences 2019年第4期10卷 631-639页

作者： Md Mozammel Haque Abdul Latif Sha Jatish Chandra Biswas Md Rafiqul Islam Aminul Islam umme Aminun naher Soil Science Division Bangladesh Rice Research Institute Gazipur Bangladesh Soil Science Division Bangladesh Rice Research Institute Gazipur Bangladesh

Background and objective: Long-term fertility study is one of the important factors to monitor changes in yield because of different nutrient management options and cropping systems involved in Asian regions. Many short-term and long-term fertilizer trials were conducted for intensive irrigated rice cropping patterns mostly to provide fertilizer rate, but did not considered sustainable soil management for soil health. The objective of the present study was to examine the effect of missing nutrient elements for a long time on rice yield, photosynthetic rate and residual soil fertility. Materials and Methods: The experiment was initiated on a permanent layout at the Bangladesh Rice Research Institute (BRRI) farm, Gazipur during 2000 to 2008 in wet season. Seven treatments in randomized complete block design with four replications were imposed. Grain yield was determined at physiological maturity from three 5 m2 areas within each plot followed by bagging and threshing. Photosynthetic was measure by Li Cor 6400 (USA) machine during study period. Soil sample was analyzed for following standard methods. Results: It was found that grain yield was in decreasing trends for the missing elements that were similar with BR 11 and BRRI dhan 31. On an average, grain yield reductions were 11.6, 7.0, 10.6, 1.1 and 3.4 percent for -n, -P, -K, -S and -Zn, than complete fertilizer treatment (nPKSZn) respectively. Under no fertilization, the ability of soil was to produce 2.9 t·ha-1 of BR11 and 3.1 t·ha-1 of BRRI dhan 31 respectively. Photosynthetic rate of rice plant was always higher in complete fertilizer treatment (nPKSZn) than missing of any nutrient element. The decrease in photosynthetic rate was more pronounced with n missing than others for both the rice varieties. Conclusion: It is concluded that balance chemical fertilizers (nPKSZn) are to be used for sustained and/or increased rice production and to maintain soil fertility.

关键词： Long-Term Fertilizer Soil nutrient Status Photosynthetic Rate Variety Yield Pattern

苯巴比妥和卡马西平应用于儿童期癫痫的副作用:随机对照研究

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英国医学杂志中文版 2007年第5期10卷 272-275页

作者： Selina H Banu Moshrat Jahan umme Kulsum Koli Saadia Ferdousi naila Z Khan Brian neville 魏研萍 clinical neurophysiologist and paediatric neurologist primary care physician trained in childhood epilepsy child psychologist professor of child development and neurology Prince of Wales's professor of childhood epilepsy

目的比较两种最常用的抗癫痫药物——苯巴比妥和卡马西平在孟加拉儿童癫痫患者中应用时的行为学副作用。设计前瞻性随机对照单中心研究。地点孟加拉 Dhaka 儿童专科医院。对象 108例2～15岁全身性强直-阵挛发作(51例)或局限性继发全身... 详细信息

目的比较两种最常用的抗癫痫药物——苯巴比妥和卡马西平在孟加拉儿童癫痫患者中应用时的行为学副作用。设计前瞻性随机对照单中心研究。地点孟加拉 Dhaka 儿童专科医院。对象 108例2～15岁全身性强直-阵挛发作(51例)或局限性继发全身性发作(57例)的患儿。主要结局评估指标癫痫控制和行为学副作用。结果 91例患儿随访12个月。6例需改用其他抗癫痫药物。比较了85例患儿的药物副作用。药物治疗和随访1年,在随访中的后1/4时间,71例患儿未再癫痫发作。随机分组后,苯巴比妥组32例102天、卡马西平组39例74天未再癫痫发作。10例患儿行为学问题增多,其中4例不能接受(苯巴比妥组1例,卡马西平组3例)。但独立 t 检验显示,两组试验药物间没有显著性差异。结论在资源缺乏的国家,苯巴比妥不引起癫痫儿童过多的行为学副作用。临床试验注册号 nCT00381537[***]。

关键词：药物副作用随机对照研究儿童期癫痫苯巴比妥卡马西平强直一阵挛发作抗癫痫药物全身性发作

A Study of Multifractal Spectra and Renyi Dimensions in 14.5A GeV/c <sup>28</sup>Si-nucleus Collisions

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Journal of Modern Physics 2014年第14期5卷 1288-1293页

作者： n. Ahmad A. Kamal M. M. Khan &nbsp Hushnud A. Tufail Applied Science Section University Polytechnic Aligarh Muslim University Aligarh India Department of Applied Physics Aligarh Muslim University Aligarh India Department of Basic Science Deanship of Prepratory Year Umme Al-Qura University Makkah KSA Department of Physics Aligarh Muslim University Aligarh India

A systematic analysis of the data on 14.5A GeV/c 28Si-nucleus collisions is carried out to investigate the behaviours of Renyi dimensions, Dq and Multifractal Spectral Function, f(αq). The Renyi dimensions, Dq are observed to decrease with increasing order of the moments, q. However, the Multifractal Spectra are concave downwards with their maxima occurring around αq =1.21±0.01. A continuous curve representing Multifractal Spectral Function, f(αq), characterizes manifestation of fluctuations in the rapidity space.

关键词： nucleus-nucleus Cillisions Multifractality and non-Statistical Fluctuatuons