检索结果-南通市图书馆

Effect of oral administration of vitamin C on human aqueous humor ascorbate concentration

在线全文

学校读者我要写书评

暂无评论

中国药理学报 1999年第10期20卷 879-883页

作者： zafar IQBAL John m mIDGLEY David G WATSON Stilianous D KARDITSAS Gordon N DUTTON William S WILSON Department of Pharmacy University of StrathclydeGlasgow G11XWUK Tennent Institute of Ophthalmology Western InfirmaryGtasgowG116NTUK Department of Pharmacology University of GlasgowGlasgow G128QQUK

AIm:To study oral administration of vitamin C on human aqueous humour ascorbate ***:High performance liquid chromatography(HPLC)coupled with electrochemical detector(BCD)was *** effect of oral administration of various doses of ascorbic acid,0(control),1.0,1.5,2.0,3.0,and 5.0 g,on its concentration in aqueous humour,obtained from volunteer cataract patients was ***:The concentration of ascorbic acid in aqueous humour of control group without administration of vitamin-C tablet or drug containing ascorbic acid was(254±119)mg·L^(-1).This study revealed that the administration of 2.0 g *** acid saturate the aqueous humour and further increase in the dose(3.0 g and 5.0 g)did not increase its concentration in aqueous humour,although its concentration was increased in ***:Oral administration of 2.0 g of Vc is sufficient to saturate the aqueous humour where it may be helpful in controlling the intra-ocular pressure.

关键词： aqueous humour ascorbic acid plasma cataract extraction high pressure liquid chromatography hydroquinones

Facile NiCo_(2)S_(4)/C nanocomposite: an efficient material for water oxidation

在线全文

学校读者我要写书评

暂无评论

Tungsten 2020年第4期2卷 403-410页

作者： umair Aftab Aneela Tahira Raffaello mazzaro Vittorio morandi muhammad Ishaq Abro muhammad moazam Baloch Junaid Ali Syed Ayman Nafady zafar Hussain Ibupoto mehran University of Engineering and Technology Jamshoro 76080Pakistan Department of Science and Technology Linköping University60174 NorrköpingSweden Institute for microelectronics and microsystems Italian National Research CouncilSection of Bologna40129 BolognaItaly College of Science King Saud UniversityRiyadh 11451Saudi Arabia Dr.m.A Kazi Institute of Chemistry University of SindhJamshoro 76080Pakistan

The water oxidation in alkaline media is a kinetically sluggish process and it requires an active electrocatalyst for overall water splitting which is a challenging task to ***,we formulate a platform for the design of efficient NiCo_(2)S_(4)/C nanocomposite using earth abundant and nonprecious *** nanocomposites are prepared by scale up hydrothermal method using different carbon contents from acid dehydrated *** are structurally and morphologically character-ized by various analytic *** scanning electron microscopy has shown few microns flower-like morphology of nanocomposite and hexagonal crystalline phase is identified by X-ray diffraction(XRD).Further,high-resolution transmission electron microscopy supported the XRD results,and C,Ni,Co and O elements were found in the composition nanocomposite as investigated by energy-dispersive *** most active nanocomposite reaches a current density of 20 mA·cm^(−2) at potential of 285 mV vs reversible hydrogen *** nanocomposite is kinetically supported by 61 mV·dec^(−1) as small Tafel *** nanocomposite is stable and durable for 40 *** electrochemical impedance spectroscopy described a small charge transfer resistance of 188.4Ω.These findings suggest that the NiCo_(2)S_(4)/C nanocomposite could be used as a promising material for an extended range of applications particularly in energy technology.

关键词： NiCo_(2)S_(4)/C Water oxidation Alkaline media Stable and durable

绝对动脉期超增强能否提高CT对不确定结节中肝细胞癌检测的敏感性

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

国际医学放射学杂志 2024年第3期 377-377页

作者： S.zafar K.Y.Elbanna A.W.m.Todd L.Guimaraes C.O'Brien A.Goel 余翔玲

摘要目的确定在CT上对不确定性结节进行相对（R）和绝对（A）动脉期过度增强（APHE）和廓清（WO）的定量评估，能否提高肝细胞癌（HCC）检测的总体敏感性。方法回顾

关键词：

鸡源产气荚膜梭菌重组酶聚合酶扩增检测方法的建立

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

中国兽医科学 2019年第12期49卷 1475-1483页

作者：许笑王艳华 m umar zafar Khan 王恒蔡建平中国农业科学院兰州兽医研究所家畜疫病病原生物学国家重点实验室甘肃兰州730046 江苏省动物重要疫病与人兽共患病防控协同创新中心江苏扬州225009

为建立鸡源产气荚膜梭菌(Clostridium perfringens)的快速诊断方法,本研究以产气荚膜梭菌α-毒素的编码基因plc为基础设计、合成引物和探针,并以real-time PCR的方法进行验证,建立了鸡源产气荚膜梭菌的重组酶聚合酶扩增(RPA)检测方法。... 详细信息

为建立鸡源产气荚膜梭菌(Clostridium perfringens)的快速诊断方法,本研究以产气荚膜梭菌α-毒素的编码基因plc为基础设计、合成引物和探针,并以real-time PCR的方法进行验证,建立了鸡源产气荚膜梭菌的重组酶聚合酶扩增(RPA)检测方法。该方法可在38℃、25 min内对产气荚膜梭菌的α-毒素编码序列进行快速特异性扩增,最低检测限量可达1×10^1copies/μL,灵敏度良好。以此方法检测实验室保存的临床样本,其检测结果与real-time PCR的检测结果一致。上述结果表明,本研究建立的real-time RPA方法在检测鸡源产气荚膜梭菌时具有操作简单、快速灵敏的特点,适用于鸡源产气荚膜梭菌的临床检测。

关键词：产气荚膜梭菌重组酶聚合酶扩增技术荧光定量检测鸡坏死性肠炎

Effect of 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide and N-hydroxysuccinimide concentrations on the mechanical and biological characteristics of cross-linked collagen fibres for tendon repair

在线全文

学校读者我要写书评

暂无评论

Regenerative Biomaterials 2015年第2期2卷 77-85页

作者： zafar Ahmad Jennifer H.Shepherd David V.Shepherd Siddhartha Ghose Simon J.Kew Ruth E.Cameron Serena m.Best Roger A.Brooks John Wardale Neil Rushton Orthopaedic Research Unit Department of Surgery University of CambridgeAddenbrooke’s HospitalCambridgeCB20QQUK Department of materials Science and metallurgy University of CambridgeCambridgeCB30FSUK Tigenix Ltd CambridgeCB40FYUK

Reconstituted type I collagen fibres have received considerable interest as tendon implant materials due to their chemical and structural similarity to the native *** produced through a semi-continuous extrusion process were cross-linked with different concentrations of the zerolength cross-linker 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide(EDC)in combination with N-hydroxysuccinimide(NHS).Tensile properties of the fibres were considered,along with imaging of both surface structure and fibrillar *** of the fibres to bacterial collagenase was investigated and fibre sections seeded with human tendon cells for biological characterization,including cell adhesion and *** work clearly demonstrated that whilst the concentration of EDC and NHS had no significant effect on the mechanics,a higher concentration was associated with higher collagenase resistance,but also provided a less attractive surface for cell adhesion and proliferation.A lower cross-linking concentration offered a more biocompatible material without reduction in mechanics and with a potentially more optimal degradability.

关键词： biopolymer scaffolds soft tissue

High-fidelity modeling of multilayer Building Process in Electron Beam Powder Bed Fusion:Build-quality Prediction and Formation-mechanism Investigation

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Journal of mechanical Engineering(Additive manufacturing Frontiers) 2023年第3期2卷 69-83页

作者： Chaochao Wu Pu Xie muhammad Qasim zafar Haiyan Zhao State Key Laboratory of Tribology Department of Mechanical EngineeringTsinghua UniversityBeijing100084China School of mechanical Engineering and Automation Fuzhou UniversityFuzhou350108China Key Laboratory for Advanced materials Processing Technology Ministry of EducationBeijing100084China Department of Aeronautics and Astronautics Stanford UniversityPalo Alto94305United States

High-fidelity simulations of powder bed fusion(PBF)additive manufacturing have made significant progress over the past *** this study,an efficient two-dimensional frame was developed for simulating the electron beam PBF process with hundreds of tracks for the direct prediction of the build *** applicable parameter range of the developed model was determined by comparing the heat transfer with that in three-dimensional ***,powder deposition and selective melting were coupled for a continuous simulation of the multilayer *** powder deposition models were utilized to generate random powder particles,and their effects on the packing structure and the resultant simulated build quality were *** predicted build quality was validated using experimental results from independent *** reproducing the building process,the defect development mechanism in a multilayer process was revealed for the coalescence behaviors of randomly distributed powder particles,which also confirmed the importance of simulation at the high-fidelity powder *** effects of key process parameters during multilayer and multi-track processes on the build quality were systematically *** particular,the formation statuses of all tracks during the simulated building process were recorded and analyzed statistically,which provided crucial information on the printing process for understanding the building mechanism or performing uncertainty analysis.

关键词： Powder bed fusion Electron beam melting Numerical simulation High-fidelity model Formation mechanism Build quality Defect

Polyimides Based on Flexible Diamines:Synthesis, Characterization and Thermal Properties

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

复旦学报（自然科学版） 2007年第5期46卷 617-页

作者： m.Saeed Butt Zareen Akhtar m.zafar-uz-Zaman Arshad munir Department of Chemistry Quaid-i-Azam UniversityIslamabad-45320 Pakistan National Engineering and Scientific Commission P.O.Box 2801 Islamabad Pakistan

1 Results and DiscussionTwo diamines 1,4-phenylene di(oxy-4,4′-aniline) and 4-aminophenyloxy-N-4-[(4-amiophenyloxy)benzylidene]aniline were prepared via the nucleopilic substitution reaction and were polymerized with 3,3′,4,4′-benzophenonetetracarboxylic acid dianhydride (BP), 4,4′-(hexafluoroisopropylidene)diphthalic anhydride (HF) , 3,4,9,10-perylenetetracarboxylic acid dianhydride (PD) and pyromellitic dianhydride (PmDA) either by one step solution polymerization reaction or two step procedure. The l...

关键词： polyimides ether diamines solubility thermal stability

Inferior glenohumeral joint dislocation with greater tuberosity avulsion

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Traumatology 2015年第3期18卷 181-183页

作者： mohd Faizan Latif zafar Jilani mazhar Abbas Yasir Salam Siddiqui Aamir Bin Sabir m.K.A. Sherwani Saifullah Khalid Department of Orthopaedic Surgery and Radiodiagnosis Jawaharlal Nehru Medical College Aligarh Muslim University Aligarh Uttar Pradesh 202002 India

Inferior glenohumeral dislocation is the least common type of glenohumeral dislocations. It may be associated with fractures of the adjacent bones and neurovascular compromise. It should be treated immediately by close reduction. The associated neuropraxia usually recovers with time. Traction-counter traction method is commonly used for reduction followed by immobilization of the shoulder for three weeks. Here, we report a case of inferior glenohumeral joint dislocation with greater tuberosity fracture with transient neurovascular compromise and present a brief review of the literature.

关键词： Shoulderjoint Shoulder dislocation Fractures bone

Determination of Ketoprofen in Human Plasma by RP-HPLC

在线全文

学校读者我要写书评

暂无评论

American Journal of Analytical Chemistry 2013年第5期4卷 252-257页

作者： Farya zafar muhammad Harris Shoaib Asia Naz Rabia Ismail Yousuf Huma Ali Department of Pharmaceutical Chemistry Faculty of PharmacyUniversity of Karachi Karachi Pakistan Department of Pharmaceutics Faculty of Pharmacy University of Karachi Karachi Pakistan Ziauddin College of Pharmacy Ziauddin University Karachi Pakistan

For in vivo pharmacokinetic studies, it is pre-requisite to quantify drug concentrations in plasma. In the present study a RP-HPLC procedure was developed and validated for the assessment of ketoprofen in human plasma. For this purpose mobile phase consisting of methaol:water (70:30) adjusted to pH 3.3 with phosphoric acid was used, and chromatography was carried out on Discovery HS C18 column, 5 μm (25 cm × 4.6 mm). The flow rate was 1 mL·min-1 and quantitative assessment was performed at 260 nm. The retention time was found to be was found to be accurate and illustrated linearity from 0.2441 to 125 μg·mL-1 with the determination coefficient (r2) of 0.9999, also accuracy and precision were found to be mL-1, 15.625 μg·mL-1, 7.812 μg·mL-1 and 1.953 μg·mL-1 were found to be 99.747%, 99.475%, 98.457% and 99.824% respectively where as for interday accuracy consecutive values for days 1, 2 and 3 were 99.104%, 99.091%, 98.96% and 99.385% in plasma. All validation parameters were assessed and were found to be within the limits. The proposed method was accurate, specific, quick (retention time min), selective (showed no interference with excipients), cost effective and a good resolution which gave this method an advantage over the different other reported methods for the estimation of ketoprofen in human plasma.

关键词： RP-HPLC Ketoprofen Linearity Accuracy Precision Specific