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Argon: a novel therapeutic option to treat neuronal ischemia and reperfusion injuries?

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Neural Regeneration Research 2015年第7期10卷 1043-1044页

作者： Felix Ulbrich ulrich Goebel Department of Anesthesiology and Intensive Care Medicine University Medical CenterFreiburg Germany

Neuronal injury and neuroprotection：Ischemia and reperfusion injuries in neuronal cells such as acute ischemic stroke-represent the third leading cause of death in the *** therapeutic concepts mainly aim to re-establ... 详细信息

关键词： a novel therapeutic option to treat neuronal ischemia and reperfusion injuries MCAO NDS OGD

DNA methylation,microRNAs,and their crosstalk as potential biomarkers in hepatocellular carcinoma

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World Journal of Gastroenterology 2014年第24期20卷 7894-7913页

作者： Sumadi Lukman Anwar ulrich Lehmann Department of Surgery Faculty of Medicine Universitas Gadjah MadaYogyakarta 55281Indonesia Institute of Pathology Medizinische Hochschule HannoverD30625 HannoverGermany

Epigenetic alterations have been identified as a major characteristic in human *** in the field of epigenetics have contributed significantly in refining our knowledge of molecular mechanisms underlying malignant *** methylation and microRNA expression are epigenetic mechanisms that are widely altered in human cancers including hepatocellular carcinoma(HCC),the third leading cause of cancer related mortality *** DNA methylation and microRNA expression patterns are regulated in developmental stage specific-,cell type specific-and tissue-specific *** aberrations are inferred in the maintenance of cancer stem cells and in clonal cell evolution during *** availability of genome-wide technologies for DNA methylation and microRNA profiling has revolutionized the field of epigenetics and led to the discovery of a number of epigenetically silenced microRNAs in cancerous cells and primary *** of these microRNAs affects several key signalling pathways in hepatocarcinogenesis suggesting that modulation of DNA methylation and/or microRNA expression can serve as new therapeutic targets for *** evidence shows that aberrant DNA methylation of certain microRNA genes is an event specifically found in HCC which correlates with unfavorable ***,it can potentially serve as a biomarker for detection as well as for prognosis,monitoring and predicting therapeutic responses in HCC.

关键词： DNA methylation MicroRNA Epigenetics Hepatocellular carcinoma Biomarker

Beyond Green Capitalism： Social-Ecological Transformation and Perspectives of a Global Green-Left

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Fudan Journal of the Humanities and Social Sciences 2016年第1期9卷 91-105页

作者： ulrich Brand Department of Political Science University of Vienna Universitatsstralβe 7/2 1010 ViennaAustria

Given certain reactions to the ecological crisis as part of the multiple crisis of capitalism （like the so-called energy transition in Germany）, a new mode of development might emerge which can be called green capitalism. This would shift the terrain of social critique and emancipatory social struggles. The paper introduces the debate on ＂social-ecological transformation＂ which emerged as a radical part of a more comprehensive debate on ＂great＂ or ＂societal transformation＂ and high- lights its core issues： the issue of a necessary attractive mode of production and living for all, the role of pioneers of change and changing political and economic institutions, the acknowledgment of shifting social practices, the requirement for alternative imaginaries or ＂stories＂ of a good life as part of a contested process which is called ＂futuring.＂ As an example for alternative imaginaries, the current debate on ＂degrowth＂ is outlined and evaluated. The second part of the paper focuses more concretely on issues around the formation and existence of a global green-left. After mentioning a crucial problem for any global alternative--i.e., the structural feature of economic and geopolitical competition which historically divided the global Left and pulled it into compromises at national or regional scales--four requirements or characteristics of a global green-left are highlighted： to weaken and change capitalistically driven competition and competitiveness, to push a social-ecological transformation in democratic ways and not at the back ofordinary people （like conservative and liberal proposals for transformation tend to do）, to link more systematically green issues with labor issues and, finally, to transform the overall dispositive of political action from a ＂distributive＂ to a ＂transformative Left.＂ One dimension of such an enhancement, it is concluded, is a broader understanding of the ＂economy＂ itself by acknowledging the demands and achievements of a ＂care revolution＂ which

关键词： Green capitalism . Social-ecological transformation - Ecological civilization · Global Left - Futuring · Degrowth · Marxism

Importance of emulsions in crystallization --applications for fat crystallization

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Frontiers of Chemical Science and Engineering 2013年第1期7卷 43-48页

作者： Sandra PETERSEN K. CHALEEPA Joachim ulrich Center for Engineering Science Thermal Process Engineering Martin Luther University Halle-Wittenberg D-06099 Halle (Saale) Germany

Emulsions and crystallization are two independent research topics which normally do not overlap although a combination of the two could be applicable to many areas. Here, the importance of emulsions in the field of fat crystallization is described. Three applications with industrial relevance were chosen for investigation： fat fractionation, the solidification of phase change materials and solid lipid nanoparticles. For fat fractionation and phase change materials, emulsification can be applied as a tool to improve the fat crystallization process, and thus the product quality of the crystallized fat. Furthermore, the use of emulsification creates new solid lipid nanoparticles in the application fields such as area of fat crystallization.

关键词： emulsion fat crystallization phase change material emulsion ffactionation emulsion solidification

Green Economy, Green Capitalism and the Imperial Mode of Living： Limits to a Prominent Strategy, Contours of a Possible New Capitalist Formation

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Fudan Journal of the Humanities and Social Sciences 2016年第1期9卷 107-121页

作者： ulrich Brand Department of Political Science University of Vienna Universitatsstraβe 7/2 1010 ViennaAustria

Since some years, the strategy of a Green Economy as a current form of ecological modernization was proposed. The paper highlights the core issues of the concept and its structural constraints. Several constraints of a far-reaching realization of a Green Economy are presented, and one constraint is highlighted, i.e., the imperial mode of （production and） living. The latter gives emphasis to the continuous and largely unquestioned access to products produced by cheap labor and under environmentally problematic conditions. This mode of living, the paper argues, is also attractive among the upper and middle classed in countries with emerging economies like China. Moreover, it compares it with the concept of sustainable development which emerged some 15 years ago. Like sustainable development, proposals for a Green Economy might become ＂a tranquilizing dis- positive＂ in order to silence doubt and criticisms. However, it is argued that, despite the improbability of realizing the ambitious objectives, the Green Economy strategy might contribute to further capitalist development. Environmental issues might be integrated into the mode of production and living. However, given capitalist and imperial structures and dynamics, this will occur in highly selective and partial ways. The author calls this emerging constellation and possible new mode of development in some countries or regions of the world Green Capitalism.

关键词： Green economy · Green capitalism · Imperial mode of living · Societal nature relations · Marxism

CFD-simulation of a circulating fluidized bed riser

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Particuology 2009年第4期7卷 283-296页

作者： Ernst-ulrich Hartge Lars Ratschow Reiner Wischnewski Joachim Werther Hamburg-University of Technology Institute of Solids Process Engineering and Particle TechnologyD-21071 HamburgGermany

In the current work, a model of the fluid mechanics in the riser of a circulating fluidized bed （CFB） has been implemented using computational fluid dynamics （CFD）. The model developed shall be used in future as the basis of 3D-reactor model for the simulation of large scale CFB combustors. The two-fluid model （TFM） approach is used to represent the fluid mechanics involved in the flow. The computational implementation is accomplished by the commercial software FLUENT. Different closure formulations are tested on a simplified geometry. Two different turbulence formulations, namely the swirl modified RNG k-e model and the Realizable k-e model, are tested in combination with two different approaches to solid phase turbulence, namely the dispersion and per phase approach. One focus of the current work is put on the study of different drag correlations. Besides the drag correlations by Syamlal et al. [Syamlal, M., Rogers, W., ＆ O＇Brien, T. J. （1993）. MFIX documentation theory guide. Technical Report DOE/METC-9411004, U.S. Department of Energy （DOE）. Morgantown Energy Technology Center： Morgantown, WV] and Gidaspow [Gidaspow, D. （1994）. Multiphaseflow andfluidization. New York： Academic Press] the EMMS model has been used to determine the momentum exchange between the two phases. The resulting formulation is then used to simulate a 1-m × 0.3-m cold CFB setup and is validated by experimental results [Schlichtharle, P. （2000）. Fluid dynamics and mixing of solids and gas in the bottom zone of circulating fluidized beds. Unoublished doctoral dissertation, Technische Universitaet Hamburg-Harburg, Shaker Verlag： Aachen].

关键词： Circulating fluidized bed Two-fuid model EMMS model Drag correlations

Bauxite washing for the removal of clay

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International Journal of Minerals,Metallurgy and Materials 2014年第11期21卷 1045-1051页

作者： Ishaq Ahmad Ernst-ulrich Hartge Joachim Werther Reiner Wischnewski Department of Mining Engineering University of Engineering and TechnologyPeshawar-25120 Pakistan Institute of Solids Process Engineering and Particle Technology Hamburg University of Technology (TUHH)Denickestrasse 1521073 Hamburg Germany Norsk Hydro Aluminum ASA Skφyen Oslo Norway

Clay impurities associated with bauxite negatively affect the Bayer process for alumina production. These impurities should be removed as far as possible by a beneficiation technique before the ore is used as feed for the Bayer process. In this current investigation, bauxite washing was conducted in the laboratory. Bauxite washing is a physical process that causes the disintegration and deagglomeration of the clay matrix, and bauxite is liberated from the clay（mainly rich in silica）. Subsequently, separation occurs with the assistance of wet screening at a predetermined cut size. Three techniques were investigated in the laboratory： drum washing, water-jet washing, and ultrasonic washing. Various operating parameters were investigated for drum washing and water-jet washing, including materials retention time, drum rotation speed, solid concentration, water-jet spray duration, pressure, and height. We concluded that the retention time of bauxite inside the drum at a solid concentration of 55wt% and a drum rotation speed of 31 r/min is the dominant parameter for the removal of clay from the bauxite surface.

关键词： beneficiation bauxite washing clay Bayer process

Inventory and Distribution of Benthic Macroinvertebrates, Indicators of Water Quality in Four Forested Watercourses in Centre Region of Cameroon

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Open Journal of Ecology 2024年第4期14卷 381-394页

作者： Eric B. Biram à Ngon Sylvie B. Chinche Josephine Ndjama Jean Dzavi Donald L. Nyame Mbia Mathias Nwaha Serge R. Gwos Nhiomock Blaise R. Mboye Ivone L. Tchaouapi ulrich Tchouta Chamberline Ngalamou Samuel Foto Menbohan Research Centre for Water and Climate Change Institute of Geological and Mining Research Yaound&#233 Cameroon Department of Fisheries and Aquatic Resources Management Buea Cameroon Laboratory of Hydrobiology and Environment University of Yaound&#233 Yaound&#233 Cameroon Laboratory of Hydrobiology and Ichthyology Libreville Gabon

The inventory of benthic macroinvertebrate species was carried out in some streams of the Mefou catchment area, from August 2021 to August 2022, in order to determine the biological groups that make up the population and characterise these environments. The dataset acquired during this study made it possible to update the existing database and contribute to the knowledge of the biological groups associated in these environments, and to provide additional information on the existing ones in relation to bioindication. Overall 80 families were identified and, on the basis of frequencies of occurrence greater than 75%, 22 families were retained as potential biological indicators. The remarkable diversity of insects and the low abundance of Diptera reflect the low degradation of environments and the good quality of water. The high diversity indices obtained reflect the maintenance of the favourable ecological conditions that favours the development of a balanced and, integrated biological community capable of adapting to changes.

关键词： Benthic Macroinvertebrates Bioindicators Biological Quality Forest Watercourse Cameroon

The ultimate goal of modeling—Simulation of system and plant performance

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Particuology 2011年第4期9卷 320-329页

作者： Joachim Werther Stefan Heinrich Maksym Dosta Ernst-ulrich Hartge Institute of Solids Process Engineering and Particle Technology Hamburg University of Technology

Modern production processes in chemical, pharmaceutical and biological industries are characterized by complex process structures, which consist of different apparatuses and process steps. Modeling the entire process requires simulating all units altogether, while taking into account interconnections between them, Nevertheless, in the area of solids processing, there is nowadays an unfilled gap from the side of computer support of process modeling in allowing effective optimization and prediction of the behavior of the whole plant, This paper presents a tool for flowsheet simulation which allows the simulation of the stationary behavior of complex processes dealing with solids and its extension towards dynamic modeling, Also, a new simulation concept is proposed on the basis of the multiscale approach. On the macroscale, fiowsheet simulation is performed with the help of the SolidSim system. Parameters for the macromodels in Solid-Sim are predicted by microscale simulation. The models for the two scales are then coupled by inter-scale communication laws. Application of the proposed modeling concept is shown by an example of fluidized bed granulation.

关键词： Flowsheet simulation Multiscale modeling Plant performance Solids processes Granulation