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Development of Composite Textile Structures for Wound Dressing Applications

Journal of Donghua University(English Edition) 2013年第5期30卷 447-450页

作者： ANAND Subhash uzun muhammet SHAH Tahir RAJENDRAN Subbiyan Institute for Materials Research and Innovation The University of Bolton Department of Textile Education Marmara University

The main objective of this research work was the development of novel and responsive nonwoven composite structures containing gelling materials for wound management. The development of novel all inclusive collagen booster(CB) therapeutic nonwoven wound dressings was mainly focused on. It provides essential functional properties such as high absorption,vertical and lateral wicking,and antibacterial and acidic pH properties. The developed composite wound dressing consisted of carboxymethylcellulose(CMC) fibre and also it was reinforced with polylactic acid( PLA) fibre. The produced composite wound dressings were treated with two different CBs at 4% by using the spray method. The details of the CBs have not been disclosed in this paper due to the Intellectual Property Rights( IPR) issues. The important benefit of using CB treatment is that it allows the maintenance of an acidic pH environment at the wound area. It is well known that acidic pH reduces the wound healing time and enhances the wound healing process. Furthermore,one of the CBs not only promotes the proliferation of the epithelial cells in wounds but also can provide antibacterial action. The PLA fibre reinforced CMC composite dressing has enhanced wicking properties which help to minimise the pooling of exudate on the wound bed and as a result maceration is prevented. The CBs treated dressings maintain the wound bed in an acidic pH condition which also improves the wound healing process. In addition to the above-mentioned properties,the CB treatment imparts antimicrobial activity against Gram-positive and Gram-negative bacteria,thus resulting in the reduction in the propensity for wound infection. Ultimately,the research has proved that the 4% CB treatment enhances the antimicrobial activity and the acidic pH characteristics of the developed CMC /PLA composite wound dressings.

关键词： nonwoven composite textile structure wound dressing carboxymethylcellulose(CMC) polylactic acid(PLA)

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Natural Walls of Anatolia: formation and development of Diş Kayalıkları as a structural landform (Sivas, Türkiye)

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Journal of Mountain Science 2023年第7期20卷 1807-1823页

作者： uzun Ali AYLAR Faruk ZEYBEK Halil Ibrahim GÜRGÖZE Serkan BAHADIR muhammet ALEMDAĞ Selçuk Geography Department Ondokuz Mayis UniversitySamsun 55100Turkey Geological Engineering Department Gümüşhane UniversityGümüşhane 29100Turkey

The Diş Kayalıkları is one of the largest and most striking examples of crests in the world and is located between Eskidere and Boğazören villages of the İmranlı district of the Sivas province in Turkey. The crests, which resemble castle walls when viewed from afar, have a real wall pattern due to the right-angled crack system of the bedrock when viewed closely. This study aims at investigating the geomorphological features of the Diş Kayalıkları and determining how the geological and geomorphological evolution of the Diş Kayalıkları took place and how the current formation mechanism continues. In the region, the mid-latitude continental climate prevails with cold humid winters and warm dry summers. The bedrock consists of Miocene bedded deposits of different resistance, folded by young tectonic movements. Diş Kayalıkları was formed by selective erosion of less resistant terrain around a pack of resistant rock on the steeper southern slope of an asymmetrical anticline. It has a length of 4750 m in the approximately northwest-southeast direction, a maximum height of 30 m, and a width varying between 5 and 8 m. In the present morphological appearance of the Diş Kayalıkları, it can be stated that the structure formed after the tectonic formation process was eroded under the control of the local climate and crest formation was realized. In the following process, the crest experienced a polycyclic process where different landforms were formed. There are smaller landforms such as karren, cave and rock window on Diş Kayalıkları, and macrofossil beds in some places. This highly attractive geomorphosite, unknown to wider public, should be investigated from various scientific aspects and should be brought to regional tourism by making the necessary infrastructure and promotion studies.

关键词： Structural landform Crest Geosite DişKayalıkları Sivas

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Presence of Fragmented QRS Complexes in Patients with Obstructive Sleep Apnea Syndrome

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Chinese Medical Journal 2015年第16期128卷 2141-2146页

作者： muhammet Rasit Sayin Murat Altuntas Ziyaeddin Aktop Ibrahim I Oz Nesimi Yavuz Ibrahim Akpinar Erol Sagatli Turgut Karabag Mustafa Aydin Department of Cardiology School of MedicineBulent Ecevit UniversityZonguldakTurkey Department of Pulmonology Uzun Mehmet State HospitalZonguldakTurkey Department of Radiology School of MedicineBulent Ecevit UniversityZonguldakTurkey Department of Cardiology Ataturk State Hospital Zonguldak Turkey

Background：Obstructive sleep apnea syndrome （OSAS） is a disease with increasing prevalence,which is mainly characterized by increased cardiopulmonary mortality and *** is well-known that OSAS patients have increased prevalence of cardiovascular diseases including coronary heart disease,heart failure,and *** aim of this study was to evaluate the presence of prolonged and fragmented QRS complexes,which have previously been associated with cardiovascular mortality,in OSAS ***：Our study included 51 patients （mean age 41.6 ± 10.1 years） who were recently diagnosed with OSAS （apnea-hypopnea index [AHI] ≥5 events/h） and never received *** control group consisted of 34 volunteers （mean age 43.1 ± 11.6 years） in whom OSAS was excluded （AHI 〈5 events/h）.The longest QRS complexes was measured in the 12-lead electrocardiogram （ECG） and the presence of fragmentation in QRS complexes was ***：Fragmented QRS frequency was significantly higher in patients with OSAS （n =31 [61%] vs.n =12 [35%],P =0.021）.QRS and QTc durations were also significantly longer in OSAS patients than controls （99.8 ± 13.9 ms vs.84.7 ± 14.3 ms,P 〈 0.001;411.4 ± 26.9 ms vs.390.1 ± 32.2 ms,P =0.001,respectively）.Analysis of the patient and controls groups combined revealed a weak-moderate correlation between AHI and QRS duration （r =0.292,P =0.070）.OSAS group had no correlation between AHI and QRS duration （r =-0.231,P =0.203）.Conclusions：In our study fragmented QRS frequency and QRS duration were found to increase in OSAS *** parameters are related with increased cardiovascular *** the prognostic importance of ECG parameters,it may be reasonable to recommend more detailed evaluation of OSAS patients with fragmented or prolonged QRS complexes with respect to presence of cardiovascular diseases.

关键词： Electrocardiogram Fragmented QRS Obstructive Sleep Apnea QRS Duration QT Duration

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