Presence of Fragmented QRS Complexes in Patients with Obstructive Sleep Apnea Syndrome

作     者：Muhammet Rasit Sayin Murat Altuntas Ziyaeddin Aktop Ibrahim I Oz Nesimi Yavuz Ibrahim Akpinar Erol Sagatli Turgut Karabag Mustafa Aydin Sayin Muhammet Rasit;Altuntas Murat;Aktop Ziyaeddin;Oz Ibrahim I;Yavuz Nesimi;Akpinar Ibrahim;Sagatli Erol;Karabag Turgut;Aydin Mustafa

作者机构：Department of CardiologySchool of MedicineBulent Ecevit UniversityZonguldakTurkey Department of PulmonologyUzun Mehmet State HospitalZonguldakTurkey Department of RadiologySchool of MedicineBulent Ecevit UniversityZonguldakTurkey Department of Cardiology Ataturk State Hospital Zonguldak Turkey 

出 版 物：《Chinese Medical Journal》 (中华医学杂志（英文版）)

年 卷 期：2015年第128卷第16期

页      面：2141-2146页

核心收录：

学科分类：0831[工学-生物医学工程（可授工学、理学、医学学位）] 1004[医学-公共卫生与预防医学(可授医学、理学学位)] 07[理学] 0707[理学-海洋科学] 08[工学] 10[医学] 

主　　题：Electrocardiogram Fragmented QRS Obstructive Sleep Apnea QRS Duration QT Duration 

摘      要：Background：Obstructive sleep apnea syndrome （OSAS） is a disease with increasing prevalence,which is mainly characterized by increased cardiopulmonary mortality and *** is well-known that OSAS patients have increased prevalence of cardiovascular diseases including coronary heart disease,heart failure,and *** aim of this study was to evaluate the presence of prolonged and fragmented QRS complexes,which have previously been associated with cardiovascular mortality,in OSAS ***：Our study included 51 patients （mean age 41.6 ± 10.1 years） who were recently diagnosed with OSAS （apnea-hypopnea index [AHI] ≥5 events/h） and never received *** control group consisted of 34 volunteers （mean age 43.1 ± 11.6 years） in whom OSAS was excluded （AHI 〈5 events/h）.The longest QRS complexes was measured in the 12-lead electrocardiogram （ECG） and the presence of fragmentation in QRS complexes was ***：Fragmented QRS frequency was significantly higher in patients with OSAS （n =31 [61%] vs.n =12 [35%],P =0.021）.QRS and QTc durations were also significantly longer in OSAS patients than controls （99.8 ± 13.9 ms vs.84.7 ± 14.3 ms,P 〈 0.001;411.4 ± 26.9 ms vs.390.1 ± 32.2 ms,P =0.001,respectively）.Analysis of the patient and controls groups combined revealed a weak-moderate correlation between AHI and QRS duration （r =0.292,P =0.070）.OSAS group had no correlation between AHI and QRS duration （r =-0.231,P =0.203）.Conclusions：In our study fragmented QRS frequency and QRS duration were found to increase in OSAS *** parameters are related with increased cardiovascular *** the prognostic importance of ECG parameters,it may be reasonable to recommend more detailed evaluation of OSAS patients with fragmented or prolonged QRS complexes with respect to presence of cardiovascular diseases.