检索结果-南通市图书馆

Viromes of Haemaphysalis longicornis reveal different viral abundance and diversity in free and engorged ticks

同方期刊数据库博看期刊评论

在线全文

学校读者我要写书评

暂无评论

Virologica Sinica 2024年第2期39卷 194-204页

作者： Jian Xiao xuan Yao Xuhua Guan Jinfeng Xiong Yaohui Fang Jingyuan Zhang You Zhang Abulimiti Moming Zhengyuan Su Jiayin Jin Yingying Ge Jun Wang Zhaojun Fan Shuang tang Shu Shen Fei Deng Key Laboratory of Virology and Biosafety and National Virus Resource Center Wuhan Institute of VirologyChinese Academy of SciencesWuhan430071China Hubei Provincial Center for Disease Control and Prevention Wuhan430070China university of Chinese Academy of Sciences Beijing101408China Hubei Jiangxia Laboratory Wuhan430200China Xinjiang Key Laboratory of Vector-borne Infectious Diseases Urumqi830002China Current address:Department of Medical Laboratory The Second Affiliated HospitalHainan Medical UniversityHaikou57000China

Haemaphysalis longicornis ticks,commonly found in East Asia,can transmit various pathogenic viruses,includingthe severe fever with thrombocytopenia syndrome virus(SFTSV)that has caused febrile diseases among humansin Hubei ***,understanding of the viromes of *** was limited,and the prevalence ofviruses among *** ticks in Hubei was not well *** study investigates the viromes of bothengorged(fed)and free(unfed)*** ticks across three mountainous regions in Hubei Province from 2019to ***-sequencing analysis identified viral sequences that were related to 39 reference viruses belonging tounclassified viruses and seven RNA viral families,namely Chuviridae,Nairoviridae,Orthomyxoviridae,Parvoviridae,Phenuiviridae,Rhabdoviridae,and *** abundance and diversity in these ticks were analysed,andphylogenetic characteristics of the Henan tick virus(HNTV),Dabieshan tick virus(DBSTV),Okutama tick virus(OKTV),and Jingmen tick virus(JMTV)were elucidated based on their full genomic *** demonstrated that DBSTV was the most common virus found in individual *** ticks(12.59%),followed by HNTV(0.35%),whereas JMTV and OKTV were not *** results improve our understanding of *** tick viromes in central China and highlight the role of tick feeding status and geographyin shaping the viral *** findings of new viral strains and their potential impact on public health raisethe need to strengthen surveillance efforts for comprehensively assessing their spillover potentials.

关键词： Ticks Virome Haemaphysalis longicornis Phylogenetic analysis Viral abundance and diversity

A widely used nonionic surfactant with desired functional groups as aqueous electrolyte additives for stabilizing Zn anode

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Rare Metals 2024年第8期43卷 3692-3701页

作者： Yue-Xian Song Xiao-Feng Wang Cai-Bin Liu Kai-xuan Guo Xu-Huan Guo Xiao-Bin Zhong Yao-Hui Zhang Kai Wang Hui-Juan Guo Li-Xin Zhang Jun-Fei Liang School of Energy and Power Engineering North University of China Key Laboratory of Green Chemical Process of Ministry of Education Hubei Key Laboratory of Novel Chemical Reactor and Green Chemical TechnologySchool of Chemical Engineering and PharmacyWuhan Institute of Technology Shanxi Provincial Key Laboratory for High Performance Battery Materials and Devices

Aqueous Zn-ion batteries（AZIBs） have emerged as potential candidates for Li-ion batteries due to their intrinsic safety and high ***,metallic Zn anodes encounter dendrite growth and water-induced corrosion,rendering poor stability and severe irreversibility at the electrode/electrolyte interface during *** stabilize the Zn anode,we report a low-cost and effective nonionic surfactant,Tween-20 polymer,as an electrolyte additive for *** Tween-20,sequential oxyethylene groups tended to be preferentially adsorbed on the Zn electrode to form a shielding layer for regulating uniform Zn ***,the hydrophobic hendecyl chains prevented H2O-induced corrosion on the Zn anode *** from the desired functional groups,when only trace amounts of Tween-20(0.050 g·L-1) were used,the Zn anode displayed good cycling stability over 2170 h at10 mA·cm-2and a high average Coulombic efficiency of98.94% over 1000 *** Tween-20 polymer can also be effectively employed in MnO2/Zn full *** their toxicity,price and amount of usage,these surfactant additives provide a promising strategy for realizing the stability and reversibility of high-performance Zn anodes.

关键词： Zn anode Dendrite growth Tween-20 polymer Surfactant additive Aqueous electrolyte

High formability Mg-Zn-Gd wire facilitates ACL reconstruction via its swift degradation to accelerate intra-tunnel endochondral ossification

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Journal of Magnesium and Alloys 2024年第1期12卷 295-315页

作者： xuan He Ye Li Hongwei Miao Jiankun Xu Michael Tim-yun Ong Chenmin Wang Lizhen Zheng Jiali Wang Le Huang Haiyue Zu Zhi Yao Jie Mi Bingyang Dai Xu Li Patrick Shu-hang Yung Guangyin Yuan Ling Qin Musculoskeletal Research Laboratory of Department of Orthopaedics&Traumatology and Innovative Orthopaedic Biomaterial and Drug Translational Research Laboratory of Li Ka Shing Institute of Health Sciences The Chinese University of Hong KongHong KongChina National Engineering Research Center of Light Alloy Net Forming School of Materials Science&EngineeringShanghai Jiao Tong UniversityShanghaiChina Department of Orthopaedics and Traumatology Li Ka Shing Faculty of MedicineThe University of Hong KongHong KongChina Orthopaedic Department Peking University Third HospitalBeijingChina Department of Rehabilitation Sciences The Hong Kong Polytechnic UniversityHong KongChina

After reconstructing the anterior cruciate ligament(ACL),unsatisfactory bone tendon interface healing may often induce tunnel enlargement at the early healing *** good biological features and high formability,Magnesium-Zinc-Gadolinium(ZG21)wires are developed to bunch the tendon graft for matching the bone tunnel during ***,tensile strength,degradation,and cytotoxicity of ZG21 wire are *** rabbit model is used for assessing the biological effects of ZG21 wire by Micro-CT,histology,and mechanical *** SEM/EDS,immunochemistry,and in vitro assessments are performed to investigate the underlying *** tests demonstrate the high formability of ZG21 wire as surgical ***-CT shows ZG21 wire degradation accelerates tunnel bone formation,and histologically with earlier and more fibrocartilage regeneration at the healing *** mechanical test shows higher ultimate load in the ZG21 *** SEM/EDS presents ZG21 wire degradation triggered calcium phosphate(Ca-P)*** results demonstrate upregulation of Wnt3a,BMP2,and VEGF at the early phase and TGFβ3 and Type II collagen at the late phase of *** vitro tests also confirmed the Ca-P in the metal extract could elevate the expression of Wnt3a,βcatenin,ocn and opn to stimulate *** vivo tests of clinical samples indicated suturing with ZG21 wire did not weaken the ultimate loading of human tendon *** conclusion,the ZG21 wire is feasible for tendon graft *** degradation products accelerated intra-tunnel endochondral ossification at the early healing stage and therefore enhanced bone-tendon interface healing in ACL reconstruction.

关键词： Magnesium wire ACL reconstruction Magnesium alloy Biomaterials Endochondral ossification

在线全文

学校读者我要写书评

暂无评论

u型组合再生混凝土-高强混凝土梁抗火性能

工程力学 2024年第6期41卷 9-18页

作者：肖建庄陈子璇同济大学土木工程学院上海200092 广西大学土木建筑工程学院南宁530004 广西大学双碳科学与技术研究院南宁530004

为突破单一混凝土材料在受力和抗火两方面的性能难以协同优化的难题,该文创新性地提出u型组合再生混凝土-高强混凝土梁(简称为RAC-HSC组合梁),系统地开展了火灾试验和常温、火后受弯试验,综合分析了不同工况下组合梁的性能表现。研究表... 详细信息

为突破单一混凝土材料在受力和抗火两方面的性能难以协同优化的难题,该文创新性地提出u型组合再生混凝土-高强混凝土梁(简称为RAC-HSC组合梁),系统地开展了火灾试验和常温、火后受弯试验,综合分析了不同工况下组合梁的性能表现。研究表明:火灾下,RAC-HSC组合梁的耐火性能显著优于高强混凝土整浇梁,其梁内温度较低,跨中挠度较小,跨中未出现明显裂缝,且未观察到爆裂现象;常温及高温后的受弯试验中,RAC-HSC组合梁的屈服荷载、极限承载力及初始刚度均显著优于再生混凝土梁,基本达到或超过普通混凝土整浇梁和高强混凝土整浇梁的水平。该文所提出的u型组合再生混凝土-高强混凝土梁是混凝土构件“抗火-受力一体化设计”的有益尝试。

关键词：组合混凝土梁再生混凝土高强混凝土抗火性能受力性能

Association of Human Whole-blood NAD+Levels with Nabothian Cyst

同方期刊数据库

同方期刊数据库博看期刊评论

在线全文

学校读者我要写书评

暂无评论

Biomedical and Environmental Sciences 2024年第5期37卷 471-478页

作者： Xu Ling WANG Yue xuan WANG Wei FAN Xue CHEN Xue Yu ZHOu Tian Yun LIu Yu He Yu Ye YANG Fan Ju Zhen Yu ZHOu Yong WANG Deng Liang Clinical Research Institute Shanghai General HospitalShanghai Jiao Tong University School of MedicineShanghai 200080China NHC Key Lab of Reproduction Regulation Shanghai Engineering Research Center of Reproductive Health Drugs and DevicesShanghai Institute for Biomedical and Pharmaceutical TechnologiesShanghai 200237China Department of Applied Statistics Johannes Kepler University LinzLinz 4040Austria Hematology Center Beijing Key Laboratory of Pediatric Hematology OncologyNational Key Discipline of Pediatrics(Capital Medical University)Key Laboratory of Major Diseases in ChildrenMinistry of EducationBeijing Children's HospitalCapital Medical UniversityNational Center for Children's HealthBeijing 100045China Department of Biostatistics School of Public HealthCheeloo College of MedicineShandong UniversityJinan 250012ShandongChina Clinical Medicine School of Basic MedicineShanghai Medical College Fudan UniversityShanghai 200032China Department of Biochemistry and Molecular Biology Hengyang Medical SchoolUniversity of South ChinaHengyang 421001HunanChina Administrative Office Total Quality Management OfficeTotal Quality Management InstituteShanghai General HospitalShanghai Jiao Tong University School of MedicineShanghai 200080China The First Affiliated Hospital of Jinan university Institute of Aging and Regenerative MedicineJinan UniversityJinan 510632GuangzhouChina Department of Scientific Research The First Affiliated Hospital of Huzhou UniversityHuzhou 313000ZhejiangChina Department of Neurosurgery Neurosurgery Research InstituteThe First Affiliated HospitalFujian Medical UniversityFuzhou 350005FujianChina Department of Neurosurgery Binhai Branch of National Regional Medical CenterThe First Affiliated HospitalFujian Medical UniversityFuzhou 350209FujianChina Fujian Provincial Institutes of Brain Disorders and Brain Sciences The First Affiliated HospitalFujian Medical UniversityFuzhou 350005FujianChina Fujian Provincial Clinical Research Center for Neurological

Objective Little is known about the association between whole-blood nicotinamide adenine dinucleotide(NAD^(+))levels and nabothian *** study aimed to assess the association between NAD^(+)levels and nabothian cysts in healthy Chinese *** Multivariate logistic regression analysis was performed to analyze the association between NAD^(+)levels and nabothian *** The mean age was 43.0±11.5 years,and the mean level of NAD^(+)was 31.3±5.3μmol/*** cysts occurred in 184(27.7%)participants,with single and multiple cysts in 100(15.0%)and84(12.6%)participants,*** total nabothian cyst prevalence gradually decreased from37.4%to 21.6%from Q1 to Q4 of NAD^(+)and the prevalence of single and multiple nabothian cysts also decreased across the NAD^(+)*** compared with the highest NAD^(+)quartile(≥34.4μmol/L),the adjusted odds ratios with 95%confidence interval of the NAD^(+)Q1 was 1.89(1.14–3.14)for total nabothian *** risk of total and single nabothian cysts linearly decreased with increasing NAD^(+)levels,while the risk of multiple nabothian cysts decreased more rapidly at NAD^(+)levels of 28.0 to35.0μmol/***:Low NAD^(+)levels were associated with an increased risk of total and multiple nabothian cysts.

关键词： Nicotinamide adenine dinucleotide Nabothian cyst Female Risk factor

LncRNA CCRR maintains Ca^(2+)homeostasis against myocardial infarction through the FTO-SERCA2a pathway

在线全文

学校读者我要写书评

暂无评论

Science China(Life Sciences) 2024年第8期67卷 1601-1619页

作者： Hua Yang Lina xuan Shengjie Wang Huishan Luo Xiaomeng Duan Jianjun Guo Shijia Cui Jieru Xin Junwei Hao Xiufang Li Jun Chen Feihan Sun Xiaolin Hu Siyun Li Ying Zhang Lei Jiao Baofeng Yang Lihua Sun Department of Pharmacology Harbin Medical University(State Key Laboratory of Frigid Zone Cardiovascular Diseasethe State-Province Key Laboratories of Biomedicine-Pharmaceutics of ChinaKey Laboratory of Cardiovascular ResearchMinistry of EducationJoint International Research Laboratory of Cardiovascular Medicine ResearchMinistry of EducationChina)College of PharmacyHarbin Medical UniversityHarbin 150081China

Cardiac conduction regulatory RNA(CCRR)has been documented as an antiarrhythmic lncRNA in our earlier *** study aimed to evaluate the effects of CCRR on SERCA2a and the associated Ca^(2+)homeostasis in myocardial infarction(MI).Overexpression of CCRR via AAV9-mediated delivery not only partially reversed ischemia-induced contractile dysfunction but also alleviated abnormal Ca^(2+)homeostasis and reduced the heightened methylation level of SERCA2a following *** effects were also observed in CCRR overexpressing transgenic mice.A conserved sequence domain of CCRR mimicked the protective function observed with the full ***,silencing CCRR in healthy mice led to intracellular Ca^(2+)overloading of *** increased SERCA2a protein stability by upregulating FTO *** direct interaction between CCRR and FTO protein was characterized by RNA-binding protein immunoprecipitation(RIP)analysis and RNA pulldown *** of NFATc3 was identified as an upstream mechanism responsible for CCRR downregulation in *** study demonstrates that CCRR is a protective lncRNA that acts by maintaining the function of FTO,thereby reducing the m^(6)A RNA methylation level of SERCA2a,ultimately preserving calcium homeostasis for myocardial contractile function in ***,CCRR may be considered a promising therapeutic strategy with a beneficial role in cardiac pathology.

关键词： CCRR calcium homeostasis FTO myocardial infarction SERCA2a

基于α-葡萄糖苷酶抑制活性评价青稞全粉提取物抑制效果及其相互作用

在线全文

学校读者我要写书评

暂无评论

粮油食品科技 2024年第3期32卷 132-139页

作者：任欣刘璇王补珍张敏王林萱北京工商大学食品与健康学院国家粮食产业(青稞深加工)技术创新中心北京市食品添加剂工程技术研究中心北京100048

青稞是我国青藏高原地区特有的粮食作物,具有良好的改善血糖代谢功效,但其具体降糖活性成分以及它们之间的配伍关系尚未明确。以青稞全粉为研究对象,提取青稞全粉中的多酚、多糖、多肽三种关键活性成分,探究青稞全粉提取物对α-葡萄糖... 详细信息

青稞是我国青藏高原地区特有的粮食作物,具有良好的改善血糖代谢功效,但其具体降糖活性成分以及它们之间的配伍关系尚未明确。以青稞全粉为研究对象,提取青稞全粉中的多酚、多糖、多肽三种关键活性成分,探究青稞全粉提取物对α-葡萄糖苷酶的抑制能力及其相互作用。通过单因素实验以及Box-Benhnken响应面优化实验,确定了利用微孔板法测定α-葡萄糖苷酶抑制活性的最佳反应体系,即酶浓度0.5 u/mL、缓冲液浓度80 mmol/L、底物浓度5 mmol/L。三种青稞全粉提取物均具有一定的α-葡萄糖苷酶抑制活性,其中青稞多酚的抑制活性最强,α-葡萄糖苷酶活性抑制率达到83.63%±2.92%,对应的IC_(50)值为0.18 mg/mL。三种青稞全粉提取物两两复配均具有一定的协同增效作用。结果可为血糖控制人群的膳食选择和功能性食品的复配开发提供理论指导。

关键词：青稞全粉活性组分 α-葡萄糖苷酶抑制活性协同配伍

在线全文

学校读者我要写书评

暂无评论

连接界面黏滑摩擦行为的非线性载荷重构方法

振动工程学报 2024年第2期37卷 200-209页

作者：王东范宣华张周锁中国工程物理研究院总体工程研究所四川绵阳621999 西安交通大学机械工程学院陕西西安710049

提出一种连接界面黏滑摩擦行为的非线性载荷重构方法。基于非线性动力学子结构建模方法,将复杂连接结构视作线性子结构和非线性连接两部分,通过虚拟非线性激励载荷进行关联。以线性子结构为研究对象,采用两次动刚度矩阵求逆的反转技术... 详细信息

提出一种连接界面黏滑摩擦行为的非线性载荷重构方法。基于非线性动力学子结构建模方法,将复杂连接结构视作线性子结构和非线性连接两部分,通过虚拟非线性激励载荷进行关联。以线性子结构为研究对象,采用两次动刚度矩阵求逆的反转技术消除传递函数的病态奇异性,建立观测点自由度和非线性连接自由度之间的传递关系。考虑连接界面黏滑摩擦行为的影响,将观测的非线性动力响应进行谐波级数展开,直接辨识连接界面的局部非线性接触载荷。利用螺栓连接梁结构的数值仿真和实验结果进行验证。结果表明:重构的虚拟非线性激励载荷能够直接反映连接界面黏滑摩擦行为的影响,并且能够有效地识别螺栓连接界面预紧性能的变化。

关键词：非线性载荷重构预紧状态识别连接界面黏滑摩擦

共线反射式二次谐波实验中二阶非线性极化率的定量测定

同方期刊数据库博看期刊评论

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Chemical Physics 2024年第2期37卷 171-176,I0101页

作者：赵璇严力耕张文凯北京师范大学物理系应用光学北京市重点实验室北京100875

偏振二次谐波是一种广泛使用的对称性表征技术.然而,在共线反射式实验构型中,光路中必不可少的分束器会导致基频光和倍频光的偏振状态经透射或反射后发生改变,从而导致二次谐波信号的偏振态发生畸变,进而影响二阶非线性极化率的定量测... 详细信息

偏振二次谐波是一种广泛使用的对称性表征技术.然而,在共线反射式实验构型中,光路中必不可少的分束器会导致基频光和倍频光的偏振状态经透射或反射后发生改变,从而导致二次谐波信号的偏振态发生畸变,进而影响二阶非线性极化率的定量测定本文提出了一种基于菲涅尔系数的数据校正方法来解决这个问题,从而实现归一化二阶非线性极化率的定量测定,进一步通过理论模拟和实验证明了该方法的有效性和通用性.

关键词：二次谐波偏振态畸变分束器二阶非线性极化率