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Neuropeptide cholecystokinin:a key neuromodulator for hippocampal functions

Neural Regeneration Research 2025年第7期20卷 1991-1992页

作者： Fengwen huang Stephen Temitayo Bello Department of Neuroscience City University of Hong KongKowloon TongHong Kong Special Administrative RegionChina Center for Regenerative Medicine and Health Hong Kong Institute of Science&InnovationChinese Academy of SciencesHong Kong Special Administrative RegionChina

Spatial memory is crucial for survival within external surroundings and wild *** hippocampus,a critical hub for spatial learning and memory formation,has received extensive investigations on how neuromodulators shape its functions(Teixeira et al.,2018;Zhang et al.,2024).However,the landscape of neuromodulations in the hippocampal system remains poorly understood because most studies focus on classical monoamine neuromodulators,such as acetylcholine,serotonin,dopamine,and *** neuropeptides,comprising the most abundant neuromodulators in the central nervous system,play a pivotal role in neural information processing in the hippocampal ***(CCK),one of the most abundant neuropeptides,has been implicated in regulating various physiological and neurobiological statuses(Chen et al.,2019).CCK-A receptor(CCK-AR)and CCK-B receptors(CCK-BR)are two key receptors mediating the biological functions of CCK,both of which belong to class-A sevenfold transmembrane g protein-coupled receptors(Nishimura et al.,2015).CCK-AR preferentially reacts to sulfated CCK,whereas CCK-BR binds both CCK and gastrin with similar affinities(Ding et al.,2022).The expression patterns of CCK-AR and CCK-BR are distinct,implying that CCK has various functions in target *** instance,CCK-AR is widely expressed in the gI and brain subregions and is hence implicated in the control of digestive function and satiety ***,CCK-BR is abundantly and widely distributed in the central nervous system,which majorly regulates anxiety,learning,and memory(Ding et al.,2022).However,the roles of endogenous CCK and CCK receptors in regulating hippocampal function at electrophysiological and behavioral levels have received less attention.

关键词： abundant functions modulator

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Enhanced post-combustion CO2 capture and direct air capture by plasma surface functionalization of graphene adsorbent

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Journal of Energy Chemistry 2025年第1期100卷 653-664页

作者： Rahul Navik Eryu Wang Xiao Ding huang Yunyi Yiyu Liu Jia Li guangdong-Hong Kong Joint Laboratory for Carbon Neutrality Jiangmen Laboratory of Carbon and Science and Technology guangzhou HKUST Fok Ying tung Research Institute The Hong Kong University of Science and Technology (guangzhou) Carbon Neutrality and Climate Change Thrust Society Hub The Hong Kong University of Science and Technology (Guangzhou) Stoddart Institute of Molecular Science Department of Chemistry Zhejiang University

graphene has enormous potential to capture CO2due to its unique properties and ***,graphene-based adsorbents have drawbacks of lower CO2adsorption capacity and poor *** work demonstrates a one-step rapid and sustainable N2/H2plasma treatment process to prepare graphene-based sorbent material with enhanced CO2adsorption *** treatment directly enriches amine species,increases surface area,and improves textural *** CO2adsorption capacity increases from 1.6 to 3.3 mmol/g for capturing flue gas,and from 0.14 to 1.3 mmol/g for direct air capture （DAC）.Importantly,the electrothermal property of the plasma-modified aerogels has been significantly improved,resulting in faster heating rates and significantly reducing energy consumption compared to conventional external heating for regeneration of *** aerogels display improved selectivity of 42 and 87 after plasma modification for 5 and 10 min,*** plasma-treated aerogels display minimal loss between 17%and 19% in capacity after 40 adsorption/desorption cycles,rendering excellent *** N2/H2plasma treatment of adsorbent materials would lower energy expenses and prevent negative effects on the global economy caused by climate change.

关键词： Carbon neutrality CO 2 capture Climate change Plasma treatment graphene aerogel

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Synergistic promotion strategy of “dual-site” and “dual-path” to enhance the C–C coupling between CO2 and HCHO driven by photoelectrocatalysis

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Journal of Energy Chemistry 2025年第1期100卷 39-49页

作者： Hongqiang Yang Jianfeng Zheng guoyu Wang Yifei gao Yatao Yang Jia Li Xiaojin Han Yan Cui Zhanggen huang National Key Laboratory of High Efficiency and Low Carbon Utilization of Coal Institute of Coal Chemistry Chinese Academy of Science University of Chinese Academy of Science Shenyang University of Chemical Technology

Photoelectrocatalytic coupling CO2and volatile organic compounds （VOCs） is a promising green strategy for the synergistic conversion of the two carbon-containing resources to *** catalytic efficiency is always at the mercy of chemical inertness of CO2and the competitive hydrogen evolution of ***,a modified g-C3N4/ZnAl-LDH Z-scheme heterojunction catalyst with dual reaction site was rationally designed and precisely *** Faraday efficiency of ethanol reached 68.67%with a corresponding formation rate of 227.3μmol *** revealed by in-situ characterizations and density functional theory calculations,CO2and HCHO were absorbed at Zn site and N site,***,*CO generated from CO2and HCHO was converted to*CH3O and*CHO on the dual-active-site *** detailed reaction mechanism experiments indicated that C–C coupling only occurred between*CO and*CH3O in electrocatalysis *** from the“*CO+*CH3O”path,another“*CO+*CHO”coupling path was also detected in photoelectrocatalytic *** selectivity of ethanol was significantly enhanced due to the synthesis of dual-site catalyst and the dual-path coupling path between CO2and HCHO simultaneously driven by light and electricity.

关键词： Photoelectrocatalysis Z-scheme C–C coupling Ethanol

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A low redox potential and long life organic anode material for sodium-ion batteries

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Journal of Energy Chemistry 2025年第1期100卷 557-564页

作者： Zhi Li Yang Wei Kang Zhou Xin huang Xing Zhou Jie Xu Taoyi Kong Junwei Lucas Bao Xiaoli Dong Yonggang Wang Department of Chemistry and Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials Institute of New Energy Collaborative Innovation Center of Chemistry for Energy Materials (iChEM) Fudan University Department of Chemistry Boston College School of Materials Science and Engineering Anhui University of Technology

Sodium-ion batteries （SIBs） with organic electrodes are an emerging research direction due to the sustainability of organic materials based on elements like C,H,O,and sodium ***,organic electrode materials for SIBs are mainly used as cathodes because of their relatively high redox potentials（>1 V）.Organic electrodes with low redox potential that can be used as anode are ***,a novel organic anode material （tetrasodium 1,4,5,8-naphthalenetetracarboxylate,Na4TDC） has been developed with low redox potential （ge mechanism was demonstrated with various in-situ/ex-situ spectroscopy and theoretical calculations,showing a high capacity of 208 mAh/g and an average decay rate of merely 0.022%per ***,the Na4TDC-hard carbon composite can further acquire improved capacity and cycling stability for 1200 cycles even with a high mass loading of up to 20 mg *** pairing with a thick Na3V2（PO4）3cathode (20.6 mg cm-2),the as-fabricated full cell exhibited high operating voltage （2.8 V）,excellent rate performance and cycling stability with a high capacity retention of 88.7% after 200 cycles,well highlighting the Na4TDC anode material for SIBs.

关键词： Organic anode material Low redox potential Composite anode Sodium-ion batteries

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Cholesterol metabolism: physiological versus pathological aspects in intracerebral hemorrhage

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Neural Regeneration Research 2025年第4期20卷 1015-1030页

作者： Ruoyu huang Qiuyu Pang Lexin Zheng Jiaxi Lin Hanxi Li Lingbo Wan Tao Wang Department of Forensic Science School of Basic Medicine and Biological SciencesSuzhou Medicine College of Soochow UniversitySuzhouJiangsu ProvinceChina

Cholesterol is an important component of plasma membranes and participates in many basic life functions,such as the maintenance of cell membrane stability,the synthesis of steroid hormones,and *** plays a key role in the establishment and maintenance of the central nervous *** brain contains 20%of the whole body’s cholesterol,80%of which is located within myelin.A huge number of processes(e.g.,the sterol regulatory element-binding protein pathway and liver X receptor pathway)participate in the regulation of cholesterol metabolism in the brain via mechanisms that include cholesterol biosynthesis,intracellular transport,and *** brain injuries or diseases involving crosstalk among the processes above can affect normal cholesterol metabolism to induce detrimental ***,we hypothesized that cholesterol-related molecules and pathways can serve as therapeutic targets for central nervous system *** hemorrhage is the most severe hemorrhagic stroke subtype,with high mortality and *** cholesterol levels are associated with the risk of intracerebral ***,secondary pathological changes after intracerebral hemorrhage are associated with cholesterol metabolism dysregulation,such as neuroinflammation,demyelination,and multiple types of programmed cell *** cholesterol accumulation in the brain has been found after intracerebral *** this paper,we review normal cholesterol metabolism in the central nervous system,the mechanisms known to participate in the disturbance of cholesterol metabolism after intracerebral hemorrhage,and the links between cholesterol metabolism and cell *** also review several possible and constructive therapeutic targets identified based on cholesterol metabolism to provide cholesterol-based perspectives and a reference for those interested in the treatment of intracerebral hemorrhage.

关键词： cell death cholesterol metabolism intracerebral hemorrhage myelination therapeutic target

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支持IPv4/IPv6双栈的5g通信网络可靠性组网部署研究

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现代电子技术 2025年第1期48卷 102-106页

作者：黄琳黄劼蒋平湖北师范大学计算机与信息工程学院湖北黄石435002 腾讯科技(深圳)有限公司广州深圳518000 湖北理工学院计算机学院湖北黄石435003

5g网络要求更多的基站部署以支持更高的数据传输速率和连接密度。为实现网络数据的并行高速传输,确保网络应用业务的实时性和稳定性,文中提出一种支持IPv4/IPv6双栈的5g通信网络可靠性组网部署方法。结合IPv4和IPv6双栈,构建双栈转换机... 详细信息

5g网络要求更多的基站部署以支持更高的数据传输速率和连接密度。为实现网络数据的并行高速传输,确保网络应用业务的实时性和稳定性,文中提出一种支持IPv4/IPv6双栈的5g通信网络可靠性组网部署方法。结合IPv4和IPv6双栈,构建双栈转换机制结合有限双协议栈模型,在模型下构建5g通信网络结构,并通过高架立体交叉网优化IPv4/IPv6双栈的5g通信网络组网结构,提升IPv4/IPv6双栈5g通信网络的通信速度。采用冗余路径算法,实现5g网络IPv4/IPv6双栈通信中的服务功能链编排,解决IPv4/IPv6双栈通信中的冗余问题。实验结果表明,该方法能够构建一种更稳定、更高效的5g通信网络组网结构,提高了网络频谱效率,优化了网络环境。

关键词： 5g通信网络 IPv4/IPv6双栈可靠性组网部署服务功能链冗余路径算法有限双协议栈模型

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Few-layer Ti3C2Tx MXene delaminated via flash freezing for high-rate electrochemical capacitive energy storage

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Journal of Energy Chemistry 2020年第9期29卷 233-240,I0007页

作者： Xianli Wang Liubing Dong Wenbao Liu Yongfeng huang Xuechao Pu Jinjie Wang Feiyu Kang Jia lia Chengjun Xu Shenzhen geim graphene Center Tsinghua Shenzhen International Graduate SchoolTsinghua UniversityShenzhen 518055GuangdongChina State Key Laboratory of New Ceramics and Fine Processing School of Materials Science and EngineeringTsinghua UniversityBeijing 100084China

Few-layer Ti3C2Tx MXene is synthesized from multi-layered Ti3C2Tx via a flash freezing-assisted delamination *** the flash freezing process,the water molecules in the interlayers of multi-layered MXene are induced to rearrange and produce volume expansion,thus notably expand the MXenes’interlayer distance to form few-layer *** synthesized few-layer Ti3C2Tx MXene nanosheets display a very small thickness(less than 5 Ti3C2 atom-layers)and expanded interlayer ***,the few-layer Ti3C2Tx exhibits enhanced capacitance(255 F g^-1 vs.177 F g^-1 for the multi-layered Ti3C2Tx)and significantly optimized rate capability(150 F g^-1 at 200 mV s^-1 vs.25 F g^-1 for the multi-layered Ti3C2Tx),because redox-active sites in the few-layer MXene are easily accessible to electrolyte ***,an asymmetric supercapacitor is constructed using the few-layer Ti3C2Tx negative electrode and an activated carbon fiber positive *** asymmetric supercapacitor presents a high energy density of 17.9 Wh kg^-1 and a high power density of 14 kW kg^-1,which is inseparable from its wide voltage window of 1.4 V and the good rate performance of the few-layer Ti3C2Tx MXene ***,the flash freezing-assist delamination provides an effective and environmental-friendly strategy to synthesize few-layer MXene materials for high-rate electrochemical energy storage.

关键词： Ti3C2Tx MXene Pseudocapacitance Activated carbon fiber Asymmetric supercapacitor Flash freezing

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Active elastic metamaterials for subwavelength wave propagation control

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Acta Mechanica Sinica 2015年第3期31卷 349-363页

作者： Y.Y.Chen g.L.huang Department of Mechanical and Aerospace Engineering University of Missouri

Recent research activities in elastic metamaterials demonstrate a significant potential for subwavelength wave propagation control owing to their interior locally resonant mechanism. The growing technological developments in electro/magnetomechanical couplings of smart materials have introduced a controlling degree of freedom for passive elastic metamaterials. Active elastic metamaterials could allow for a fine control of material physical behavior and thereby induce new functional properties that cannot be produced by passive approaches. In this paper, two types of active elastic metamaterials with shunted piezoelectric materials and electrorheological elastomers are proposed. Theoretical analyses and numerical validations of the active elastic metamaterials with detailed microstructures are pre- sented for designing adaptive applications in band gap structures and extraordinary waveguides. The active elastic metamaterial could provide a new design methodology for adaptive wave filters, high signal-to-noise sensors, and structural health monitoring applications.

关键词： Active elastic metamaterials Subwavelengthwave control Adaptive metastructures Smart materials

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淤地坝溃坝风险性评估综述

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灾害学 2025年第1期40卷 123-128,134页

作者：黄波张耀南中国科学院西北生态环境资源研究院兰州甘肃730000 中国科学院大学北京1000493 国家冰川冻土沙漠科学数据中心兰州甘肃730000 甘肃省科学数据总中心兰州甘肃730000

淤地坝作为一种关键的防灾减灾设施,对于粮食生产、水资源保持和洪水控制等方面发挥着至关重要的作用。上世纪六七十年代修建的大部分淤地坝面临淤满失效问题,突发的暴雨、地震等自然灾害将极大概率引起溃决,从而导致引发更为严重的次... 详细信息

淤地坝作为一种关键的防灾减灾设施,对于粮食生产、水资源保持和洪水控制等方面发挥着至关重要的作用。上世纪六七十年代修建的大部分淤地坝面临淤满失效问题,突发的暴雨、地震等自然灾害将极大概率引起溃决,从而导致引发更为严重的次生灾害。该文通过梳理黄土高原淤地坝溃坝风险性评价文献,总结了现有淤地坝溃坝风险性评价方法。结果表明,传统淤地坝风险性评价方法对影响因素数据的依赖程度很高;选取评价因子及其权重赋予存在较强的主观经验性;缺乏大范围的风险评估。因此,该文建议整合数据驱动模型的研究思路,利用多源数据,区域尺度上开展淤地坝溃坝风险性评价,为相关部门提供更可靠的决策支持,及具有提高防灾减灾能力实践意义。

关键词：淤地坝溃坝数据工程风险性评价

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Boundedness and Spectrum of Multiplicative Convolution Operators Induced by Arithmetic Functions

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Acta Mathematica Sinica,English Series 2019年第8期35卷 1300-1310页

作者： Kibrom g.EBREMESKEL Lin Zhe huang Academy of Mathematics and Systems Science Chinese Academy of SciencesBeijing 100190P.R.China Department of Mathematics College of Natural and Computational SciencesAksum UniversityAksumTigrayEthiopia

In this paper, we consider a multiplicative convolution operator Mf acting on a Hilbert spaces l^2(N,ω;). In particular, we focus on the operators M1 and Mμ, where μ, is the Mobius function. We investigate conditions on the weight ω under which the operators M1 and Mμ are bounded. We show that for a positive and completely multiplicative function f,M1 is bounded on l^2(N, f^2) if and only if ||f||1 gously, we show that Mμ is bounded on l^2(N, 1/n^2α) with ||M1||2,ω=ζ(α)/ζ(2α),where ωn= 1 /n^2α,α> 1. As an application, we obtain some results on the spectrum of M1^*M1 and M^*μMμ. Moreover, von Neumann algebra generated by a certain family of bounded operators is also considered.

关键词： Arithmetic functions Mobius function von Neumann algebra

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