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Antidiabetic and antioxidant activities of red seaweed Laurencia dendroidea

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Asian Pacific Journal of Tropical Biomedicine 2019年第12期9卷 501-509页

作者： The Han nguyen Thi Huyen nguyen Van Minh nguyen Thi Lan Phuong nguyen Thi Van anh Tran anh Duy Do Sang Moo Kim Faculty of Food Technology Nha Trang University02 Nguyen Dinh Chieu StreetNha Trang CityKhanh HoaVietnam Quality Control Department Institute of Vaccines and Medical BiologicalsNha Trang CityKhanh HoaVietnam Faculty of Pharmacy University of Medicine and Pharmacy of Ho Chi Minh City41 Dinh Tien Hoang StreetHo Chi Minh CityVietnam Research Department of Marine Conservation Research Institute for Marine Fisheries224 Le Lai StreetHai Phong CityVietnam Department of Marine Food Science and Technology Gangneung-Wonju National University7 Jukheon-gilGangneung 25457Republic of Korea

Objective:To investigate antidiabetic and antioxidant activities of the extract and fractions from Vietnamese red seaweed Laurencia ***:The seaweed Laurencia dendroidea was extracted by using microwave-assisted extraction method in 80%*** seaweed extract was then fractionated using different solvents(n-hexane,chloroform,ethyl acetate,butanol and water).These obtained fractions were evaluated forα-glucosidase inhibitory and antioxidant *** activities were tested using DPPH,nitric oxide radical scavenging and metal chelating *** enzyme inhibition mode was determined using Lineweaver-Burk *** acidic and thermal stabilities,the ethyl acetate fraction was treated at pH 2.0 and 100℃,*** residual inhibitory activity of the fraction was calculated based on the initial inhibitory *** in vivo antidiabetic activity,mice were divided into four groups,including normal control,diabetic control,diabetic mice treated with ethyl acetate fraction and diabetic mice treated with *** glucose level of treated mice during acute and prolonged treatments was *** evaluate the toxicity of the ethyl acetate fraction,the body weight changes and activities of liver function enzymes(aspartate transaminase,alanine transaminase and gammaglutamyl transferase)were carried ***:The extract of Laurencia dendroidea showed strongα-glucosidase inhibitory and DPPH radical scavenging *** concentrations affected bothα-glucosidase inhibitory and antioxidant activities.A 80%aqueous methanol was the suitable solvent for extraction of enzyme inhibitors and *** solvent fractions,ethyl acetate fraction had the highest inhibitory activities againstα-glucosidase with a mixed type of inhibition and the strongest antioxidant activities,and was stable under acidic and thermal *** ethyl acetate fraction treated diabetic mice significantly reduced blood glucose level compare

关键词： α-Glucosidase inhibitor Antidiabetic Antioxidant Red seaweeds Vietnam

Studies on sustainable features of vernacular architecture in different regions across the world:A comprehensive synthesis and evaluation

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Frontiers of Architectural Research 2019年第4期8卷 535-548页

作者： anh tuan nguyen nguyen Song Ha Truong David Rockwood anh Dung Tran Le Faculty of Architecture the University of Danang-University of Science and TechnologyDa NangViet Nam School of Architecture University of Hawaii at ManoaUSA Laborotoire des Technologies Innovantes(LTI) Universite de Picardie Jules VerneFrance

Due to the increasing pressure brought by recent global environmental problems,building designers are embracing regionalism and the knowledge of traditional structures,arguing that these structures are energy efficient and highly *** observe clear evidence of the increasing interest in vernacular architecture among the research *** study therefore aims to clarify the contents and issues raised in the studies on vernacular architecture and the knowledge and recommendations that can be derived from them.A database of the research is established by collecting many studies from primary *** data is carefully refined and categorized into a table where synthesized information is *** results of this study show an uneven geographic and climatic distribution of the studies;the trend in selecting research objectives and research objects;the choice of research methods with a clear shift towards quantitative research methods,and the generic findings from the database of the *** results can support diverse inquiries about vernacular architecture across the world and be used as a resource or an orientation to support numerous subsequent studies.

关键词： Vernacular architecture Traditional architecture Sustainable feature Research method Building design

Land subsidence prediction for a new urban mass rapid transit line in Hanoi

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Underground Space 2020年第2期5卷 93-104页

作者： Pham Huy Giao Vu Thi Hue nguyen Dang Han nguyen Thi Hai anh nguyen Ngoc Minh Asian Institute of Technology BangkokThailand Institute of Foundation and Underground FECONHanoiViet Nam Sonhai JSC Viet Nam

The rapidly increasing population,urbanization,and industrialization of Hanoi city in the last few decades have necessitated the urgent development of a new underground public transport infrastructure such as the urban mass rapid transit(UMRT)system that is now under ***,concerns on the possible effects of land subsidence on the to-be-constructed and operated UMRT lines must be *** of the difficulties while assessing land subsidence in Hanoi is the insufficient subsidence monitoring ***,a good geotechnical characterization of the subsoil profile and proper numerical analysis can help predict groundwater pumping-induced subsidence *** UMRT line No.2 that was selected for this study is special as it runs across the old quarter downtown,located at the very heart of Hanoi *** this paper,the Hanoi aquifer system,groundwater extraction,and subsidence monitoring network of Hanoi are reviewed *** data from 30 investigation boreholes were analyzed to characterize the subsoil profile underlying a segment of the UMRT line No.2 that consists of both elevated and underground *** soil layers were identified up to a depth of 50 m,including a compressible soft clay layer 10-15 m thick that is supposed to be most vulnerable to subsidence by groundwater *** on the long-term groundwater monitoring data,one-dimensional finite element method(FEM)consolidation analyses were carried out for three drawdown boundary conditions of 5,10,and 15 m and yielded a total subsidence of 0.15,0.35,and 0.5 m,respectively,after 25 years with 1994 as the reference *** results of this study confirmed that land subsidence in particular should be considered in the construction and maintenance of the UMRT lines in Hanoi,in particular for underground sections that are founded on soft to medium clay layers.

关键词： Hanoi aquifer system Groundwater pumping Land subsidence UMRT line Geotechnical characterization

Building 3D CityGML models of mining industrial structures using integrated UAV and TLS point clouds

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International Journal of Coal Science & Technology 2023年第5期10卷 158-177页

作者： Canh Le Van Cuong Xuan Cao anh Ngoc nguyen Chung Van Pham Long Quoc nguyen Department of Mine Surveying Hanoi University of Mining and GeologyHanoiVietnam Viettel Group Viettel Cyberspace CenterHanoiVietnam

Mining industrial areas with anthropogenic engineering structures are one of the most distinctive features of the real world.3D models of the real world have been increasingly popular with numerous applications,such as digital twins and smart factory *** this study,3D models of mining engineering structures were built based on the CityGML *** collecting spatial data,the two most popular geospatial technologies,namely UAV-SfM and TLS were *** accuracy of the UAV survey was at the centimeter level,and it satisfied the absolute positional accuracy requirement of creat-ing all levels of detail(LoD)according to the CityGML ***,the UAV-SfM point cloud dataset was used to build LoD 2 *** addition,the comparison between the UAV-SfM and TLS sub-clouds of facades and roofs indicates that the UAV-SfM and TLS point clouds of these objects are highly consistent,therefore,point clouds with a higher level of detail and accuracy provided by the integration of UAV-SfM and TLS were used to build LoD 3 *** resulting 3D CityGML models include 39 buildings at LoD 2,and two mine shafts with hoistrooms,headframes,and sheave wheels at LoD3.

关键词： 3D modelling CityGML-Mining industry UAV Terrestrial laser scanning Point cloud

Combining Entropy Optimization and Sobel Operator for Medical Image Fusion

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Computer Systems Science & Engineering 2023年第1期44卷 535-544页

作者： nguyen tu Trung Tran Thi Ngan Tran Manh tuan To Huu nguyen Faculty of Computer Science and Engineering Thuyloi University175 Tay SonDong DaHanoi010000Vietnam University of Information and Communication Technology Thai Nguyen UniversityThai Nguyen240000Vietnam

Fusing medical images is a topic of interest in processing medical *** is achieved to through fusing information from multimodality images for the purpose of increasing the clinical diagnosis *** fusion aims to improve the image quality and preserve the specific *** methods of medical image fusion generally use knowledge in many differentfields such as clinical medicine,computer vision,digital imaging,machine learning,pattern recognition to fuse different medical *** are two main approaches in fusing image,including spatial domain approach and transform domain *** paper proposes a new algorithm to fusion multimodal *** algorithm is based on Entropy optimization and the Sobel *** transform is used to split the input images into components over the low and high frequency ***,two fusion rules are used for obtaining the fusing *** rule,based on the Sobel operator,is used for high frequency *** second rule,based on Entropy optimization by using Particle Swarm Optimization(PSO)algorithm,is used for low frequency *** algorithm is implemented on the images related to central nervous system *** experimental results of the paper show that the proposed algorithm is better than some recent methods in term of brightness level,the contrast,the entropy,the gradient and visual informationfidelity for fusion(VIFF),Feature Mutual Information(FMI)indices.

关键词： Medical image fusion wavelet entropy optimization PSO Sobel operator

New guidelines for fluorophore application in peroxisome targeting analyses in transient plant expression systems

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Journal of Integrative Plant Biology 2019年第7期61卷 884-899页

作者： Christian Falter nguyen Binh anh Thu Saugat Pokhrel Sigrun Reumann Plant Biochemistry and Infection Biology Institute of Plant Science and Microbiology University of Hamburg

Peroxisome research has been revolutionized by proteome studies combined with in vivo subcellular targeting analyses. Yellow and cyan fluorescent protein(YFP and CFP) are the classical fluorophores of plant peroxisome research. In the new transient expression system of Arabidopsis seedlings co-cultivated with Agrobacterium we detected the YFP fusion of one candidate protein in peroxisomes, but only upon co-transformation with the peroxisome marker, CFP-PTS1. The data suggested that the YFP fusion was directed to peroxisomes due to its weak heterodimerization ability with CFP-PTS1,allowing piggy-back import into peroxisomes. Indeed, if co-expressed with monomeric Cerulean-PTS1(mCer-PTS1),the YFP fusion was no longer matrix localized. We systematically investigated the occurrence and extent of dimerization-based piggy-back import for different fluorophore combinations in five major transient plant expression systems. In Arabidopsis seedlings and tobacco leaves both untagged YFP and monomeric Venus were imported into peroxisomes if co-expressed with CFP-PTS1 but not with mCer-PTS1. By contrast, piggy-back import of cytosolic proteins was not observed in Arabidopsis and tobacco protoplasts or in onion epidermal cells for any fluorophore combination at any time point. Based on these important results we formulate new guidelines for fluorophore usage and experimental design to guarantee reliable identification of novel plant peroxisomal proteins.

关键词： transient plant expression systems fluorophore

Numerical analysis of plasma arc physical characteristics under additional constraint of keyhole

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Chinese Physics B 2018年第3期27卷 306-313页

作者： Bin Xu Fan Jiang Shujun Chen Manabu Tanaka Shinichi Tashiro nguyen Van anh Engineering Research Center of Advanced Manufacturing Technology for Automotive Components Ministry of EducationBeijing 100124China joining and Welding Research Institute Osaka UniversityOsaka 567-0047Japan

The physical characteristics of a plasma arc affect the stability of the keyhole and weld pool directly during keyhole plasma arc welding(KPAW).There will be significant change for these characteristics because of the interaction between the keyhole weld pool and plasma arc after ***,in order to obtain the temperature field,flow field,and arc pressure of a plasma arc under the reaction of the keyhole,the physical model of a plasma arc with a pre-set keyhole was *** addition,the tungsten and base metal were established into the calculated domain,which can reflect the effect of plasma arc to weld pool *** on magneto hydrodynamics and Maxwell equations,a twoSdimensional steady state mathematical model was *** the heat production of anode and cathode,the distribution of temperature field,flow field,welding current density,and plasma arc pressure were solved out by the finite difference *** the calculated results,it is found that the plasma arc was compressed a second time by the *** additional constraint results in an obvious rise of the plasma arc pressure and flow velocity at the minimum diameter place of the keyhole,while the temperature field is impacted ***,the observational and metallographic experiments are conducted,and the shapes of plasma arc and fusion line agree with the simulated results generally.

关键词： characteristics of plasma arc interaction of keyhole and plasma arc pre-set keyhole model nu-merical analysis

A New Inertial Self-adaptive Gradient Algorithm for the Split Feasibility Problem and an Application to the Sparse Recovery Problem

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Acta Mathematica Sinica,English Series 2023年第12期39卷 2489-2506页

作者： nguyen The VINH Pham Thi HOAI Le anh DUNG Yeol Je CHO Department of Mathematical Analysis University of Transport and Communications3 Cau Giay StreetHanoiVietnam Department of Applied Mathematics School of Applied Mathematics and InformaticsHano University of Science and Technology1 Dai Co Viet RoadHanoiVietnam Department of Mathematics and Informatics Hanoi University of Education136 Xuan ThuyCau GiayHanoiVietnam Department of Mathematics Education Gyeongsang National UniversityJinju52828Republicof Korea

In this paper,by combining the inertial technique and the gradient descent method with Polyak's stepsizes,we propose a novel inertial self-adaptive gradient algorithm to solve the split feasi-bility problem in Hilbert spaces and prove some strong and weak convergence theorems of our method under standard *** examine the performance of our method on the sparse recovery prob-lem beside an example in an infinite dimensional Hilbert space with synthetic data and give some numerical results to show the potential applicability of the proposed method and comparisons with related methods emphasize it further.

关键词： Split feasibility problem CQ algorithm Hilbert space sparse recovery problem

Adaptive data fusion framework for modeling of non-uniform aerodynamic data

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Chinese Journal of Aeronautics 2023年第7期36卷 316-336页

作者： Vinh PHAM Maxim TYAN tuan anh nguyen Chi-Ho LEE L.V.Thang nguyen Jae-Woo LEE Department of Aerospace Information Engineering Konkuk UniversitySeoul 05029Republic of Korea Konkuk Aerospace Design-Airworthiness Institute Konkuk UniversitySeoul 05029Republic of Korea

Multi-fidelity Data Fusion(MDF)frameworks have emerged as a prominent approach to producing economical but accurate surrogate models for aerodynamic data modeling by integrating data with different fidelity ***,most existing MDF frameworks assume a uniform data structure between sampling data sources;thus,producing an accurate solution at the required level,for cases of non-uniform data structures is *** address this challenge,an Adaptive Multi-fidelity Data Fusion(AMDF)framework is proposed to produce a composite surrogate model which can efficiently model multi-fidelity data featuring non-uniform ***,the design space of the input data with non-uniform data structures is decomposed into subdomains containing simplified ***,different MDF frameworks and a rule-based selection process are adopted to construct multiple local models for the subdomain *** the other hand,the Enhanced Local Fidelity Modeling(ELFM)method is proposed to combine the generated local models into a unique and continuous global ***,the resulting model inherits the features of local models and approximates a complete database for the whole design *** validation of the proposed framework is performed to demonstrate its approximation capabilities in(A)four multi-dimensional analytical problems and(B)a practical engineering case study of constructing an F16C fighter aircraft’s aerodynamic *** comparisons of the generated models using the proposed AMDF framework and conventional MDF approaches using a single global modeling algorithm are performed to reveal the adaptability of the proposed approach for fusing multi-fidelity data featuring non-uniform ***,the results indicated that the proposed framework outperforms the state-of-the-art MDF approach in the cases of non-uniform data.

关键词： Aerodynamic modeling Data fusion Diverse data structure Multi-fidelity data Multi-fidelity surrogate modeling