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Control Policy learning Design for Vehicle Urban Positioning via BeiDou Navigation

Journal of Systems Science & Complexity 2024年第1期37卷 114-135页

作者： QIN Yahang ZHANG Chengye CHEN ci XIE Shengli lEWIS Frank l School of Automation Guangdong University of TechnologyGuangzhou 510006China Guangdong Key laboratory of IoT Information Technology Guangzhou 510006China. Center for Intelligent Batch Manufacturing Based on IoT Technology Key laboratory of Intelligent Detection and The Internet of Things in Manufacturing Ministry of EducationGuangzhou 510006China Guangdong-HongKong-Macao Joint laboratory for Smart Discrete Manufacturing Guangzhou 510006China Key laboratory of Intelligent Information Processing and System Integration of IoT Ministry of EducationGuangzhou 510006China. UTA Research Institute The University of Texas at ArlingtonFort WorthTX 76019USA

This paper presents a learning-based control policy design for point-to-point vehicle positioning in the urban environment via BeiDou *** navigating in urban canyons,the multipath effect is a kind of interference that causes the navigation signal to drift and thus imposes severe impacts on vehicle localization due to the reflection and diffraction of the BeiDou ***,the authors formulated the navigation control system with unknown vehicle dynamics into an optimal control-seeking problem through a linear discrete-time system,and the point-to-point localization control is modeled and handled by leveraging off-policy reinforcement learning for feedback *** proposed learning-based design guarantees optimality with prescribed performance and also stabilizes the closed-loop navigation system,without the full knowledge of the vehicle *** is seen that the proposed method can withstand the impact of the multipath effect while satisfying the prescribed convergence rate.A case study demonstrates that the proposed algorithms effectively drive the vehicle to a desired setpoint under the multipath effect introduced by actual experiments of BeiDou navigation in the urban environment.

关键词： BeiDou navigation multipath effect prescribed convergence rate reinforcement learning urban localization.

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Dark Matter Search in Dwarf Irregular Galaxies with Ten Years of Data from the Ice Cube Neutrino Observatory

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Research in Astronomy and Astrophysics 2024年第3期24卷 75-82页

作者： Yi-Fei lü Ben-Yang Zhu Rong-lan li Xue-Kang Guo Tian-ci liu Yong-Bo Huang Yun-Feng liang Guangxi Key laboratory for Relativistic AstrophysicsSchool of Physical Science and TechnologyGuangxi University Nanning 530004China

Dwarf irregular galaxies(dIrrs),as rotationally supported systems,have more reliable J-factor measurements than dwarf spheroidal galaxies and have received attention as targets for dark matter detection in recent *** this paper,we use 10 yr of IceCube muon-track data and an unbinned maximum-likelihood-ratio method to search for neutrino signals beyond the background from the directions of seven dIrrs,aiming to detect neutrinos produced by heavy annihilation dark *** do not detect any significant *** on such null results,we calculate the upper limits on the velocity-averaged annihilation cross section for 1 TeV–10 PeV dark *** limits,although weaker than the strictest constraints in the literature in this mass range,are also a good complement to the existing results considering the more reliable J-factor measurements of dIrrs.

关键词： (cosmology) dark matter-cosmology theory-galaxies dwarf

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Comparing the efficacy and safety of low,medium,and high dosages of selexipag for treating pulmonary hypertension:A systematic review and meta-analysis

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Animal Models and Experimental Medicine 2024年第1期7卷 56-70页

作者： Shang Wang Yi Yan Jian Zhang Ping Yuan ci-Jun luo Hong-ling Qiu Hui-Ting li Jian Xu lan Wang Tian-lan li Rong Jiang Department of Cardio-Pulmonary circulation Shanghai Pulmonary HospitalSchool of MedicineTongji UniversityShanghaiChina Heart Center and Shanghai Institute of Pediatric Congenital Heart Disease Shanghai Children's Medical CenterNational Children's Medical CenterShanghai Jiaotong University School of MedicineShanghaiChina Department of Respiratory and Critical Care Medicine The 416 Hospital of Nuclear IndustryThe Second Affiliated Hospital of Chengdu Medical CollegeChengduChina Department of Hematology The Affiliated Hospital of Qingdao UniversityQingdaoChina

Background:The maintenance dosage of selexipag is categorized as low,medium or *** order to assess the efficacy and safety of different dosages of selexipag for the risk stratification of pulmonary arterial hypertension(PAH),we performed a sys-tematic review and ***:Studies assessing PAH risk stratification indices,such as the World Health Organization functional class(WHO-FC),six-minute walk distance(6MWD),N-terminal pro-B-type natriuretic peptide(NT-proBNP)level,right atrial pressure(RAP),cardiac index(ci)and mixed venous oxygen saturation(SvO2),were ***:Thirteen studies were *** led to improvements in the 6MWD(MD:24.20 m,95%ci:10.74-37.67),NT-proBNP(SMD:-0.41,95%ci:-0.79-0.04),ci(MD:0.47 l/min/m^(2),95%ci:0.17-0.77)and WHO-FC(OR:0.564,95%ci:0.457-0.697).Subgroup analysis demonstrated that all three dosages improved the 6MWD.A moderate dosage led to improvements in the ci(MD:0.30 l/min/m^(2),95%ci:0.15-0.46)and WHO-FC(OR:0.589,95%ci:0.376-0.922).Within 6 months of treatment,only the WHO-FC and ci were significantly improved(OR:0.614,95%ci:0.380-0.993;MD:0.30 l/min/m^(2),95%ci:0.16-0.45,respectively).More than 6 months of treatment significantly improved the 6MWD,WHO-FC and NT-proBNP(MD:40.87 m,95%ci:10.97-70.77;OR:0.557,95%ci:0.440-0.705;SMD:-0.61,95%ci:-1.17-0.05,respectively).Conclusions:low,medium,and high dosages of selexipag all exhibited good *** treatment lasted for more than 6 months,selexipag exerted obvious effects,even in the low-dosage *** finding is important for guiding individualized treatments.

关键词： individualized treatments meta-analysis prostacyclin receptor agonist risk stratification systematic review

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Optimized new Shengmai powder(优化新生脉散方) inhibits myocardial fibrosis in heart failure by regulating the rat sarcoma/rapidly accelerated fibrosarcoma/mitogen-activated protein kinase kinase/extracellular regulated protein kinases signaling pathway

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Journal of traditional Chinese Medicine 2024年第3期44卷 448-457页

作者： ZHANG Zeyu JIA Zhuangzhuang SONG Yuwei ZHANG Xuan WANG ci WANG Shuai ZHANG Peipei REN Qiuan WANG Xianliang MAO Jingyuan Department of Cardiovascular the First Teaching Hospital of Tianjin University of Traditional Chinese MedicineNational Clinical Research Center for Chinese Medicine Acupuncture and MoxibustionTianjin 300381China

OBJECTIVE: Exploring the effect of Optimized New Shengmai powder(优化新生脉散方, ONSMP) on myocardial fibrosis in heart failure(HF) based on rat sarcoma(RAS)/rapidly accelerated fibrosarcoma(RAF)/mitogen-activated protein kinase kinase(MEK)/extracellular regulated protein kinases(erK) signaling pathway. METHODS: Randomized 70 Sprague-Dawley rats into sham(n = 10) and operation(n = 60) groups, then established the HF rat by ligating the left anterior descending branch of the coronary artery. We randomly divided the operation group rats into the model, ONSMP [including low(l), medium(M), and high(H) dose], and enalapril groups. After the 4-week drug intervention, echocardiography examines the cardiac function and calculates the ratios of the whole/left heart to the rat's body weight. Finally, we observed the degree of myocardial fibrosis by pathological sections, determined myocardium collagen(COl) Ⅰ and COl Ⅲ content by enzyme-linked immunosorbent assay, detected the m RNA levels of COl Ⅰ, COl Ⅲ, α-smooth muscle actin(α-SMA), and c-Fos proto-oncogene(c-Fos) by universal real-time, and detected the protein expression of p-RAS, p-RAF, p-MEK1/2, p-erK1/2, p-ETS-like-1 transcription factor(p-ElK1), p-c-Fos, α-SMA, COl Ⅰ, and COl Ⅲ by Western blot. RESUlTS: ONSMP can effectively improve HF rat's cardiac function, decrease cardiac organ coefficient, COl volume fraction, and COl Ⅰ/Ⅲ content, down-regulate the m RNA of COl Ⅰ/Ⅲ, α-SMA and c-Fos, and the protein of p-RAS, p-RAF, p-MEK1/2, p-erK1/2, p-ElK1, c-Fos, COl Ⅰ/Ⅲ, and α-SMA. CONClUSIONS: ONSMP can effectively reduce myocardial fibrosis in HF rats, and the mechanism may be related to the inhibition of the RAS/RAF/MEK/erK signaling pathway.

关键词： myocardial fibrosis heart failure sarcoma rapidly accelerated fibrosarcoma mitogen-activated protein kinases extracellular regulated protein kinases optimized new Shengmai powder

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Microbial phenolic metabolites are associated with better frontal lobe cognition

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Food Science and Human Wellness 2024年

作者： Inés Domínguez-lópez Isabella Parilli-Moser Anna Vallverdú-Queralt Anna tresserra-Rimbau cinta Valls-Pedret Zenaida Vázquez-Ruiz Olga Casta?er Ramon Estruch Emili Ros Rosa M.lamuela-Raventós lipid Clinic， Endocrinology and Nutrition Service， Institut d'Investigacions Biomèdiques August Pi i Sunyer， Hospital Clínic 08036 Barcelona， Spain Unit of Cardiovascular Risk and Nutrition， Institut Hospital del Mar de Investigaciones Médicas (IMIM) Department of Preventive Medicine and Public Health， University of Navarra Departament de Nutr.ció， ciències de l'Alimentació i Gastronomía， Facultat de Farmacia， Universitat de Barcelon (UB)， Av.de Joan XXII Department of Endocrinology， Hospital Clinic IDIBAPS， Barcelona， Spain Department of Internal Medicine， Hospital Clinic， Institut d'Investigació Biomèdica August Pi i Sunyer (IDIBAPS)， University of Barcelona ciBer Fisiopatología de la Obesidad y Nutr.ción (ciBerOBN)， Instituto de Salud Carlos III Institut de Nutr.ció i Seguretat Alimentària (INSA)， Universitat de Barcelona (UB)

With increasing life expectancy， neurodegenerative diseases have become one of the leading causes of ill-health in the elderly. Preventive strategies include following healthy diets， such as the Mediterranean diet， which is particularly rich in polyphenols， bioactive compounds with neuroprotective properties. The aim of this study was to assess the association of microbial phenolic metabolites (MPM) with cognition. This cross-sectional analysis was performed with 200 participants of the PREDIMED trial (Barcelona-Clinic recruitment center). A novel method based on liquid chromatography coupled to mass spectrometry was used to identify urinary MPM (protocatechuic acid， enterodiol glucuronide， enterolactone glucuronide， urolithin B glucuronide， and vanillic acid glucuronide)， and cognitive function was evaluated with neuropsychological tests. Multivariable-adjusted ordinary least squares regression was used to assess the associations between cognitive function and MPM， and a score was calculated as the weighted sum of MPM. A higher MPM score was associated with better frontal lobe function. Among individual metabolites， vanillic acid glucuronide was correlated with frontal cognitive performance. Participants with higher concentrations of vanillic acid glucuronide and urolithin B glucuronide obtained better scores in the Color trail test part 2. A higher score for urinary multi-MPM was associated with better frontal cognitive performance in an older Mediterranean population.

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融合多结构信息的代码注释生成模型

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计算机工程与科学 2024年第4期46卷 667-675页

作者：余天赐高尚江苏科技大学计算机学院江苏镇江212100

代码注释可以帮助开发人员理解代码的功能和实现方法。代码注释生成模型可以自动识别代码中的关键信息,并生成相关注释,提高代码的可读性和可维护性。现有的代码注释生成模型通常只使用抽象语法树结构信息来表示代码,导致模型生成注释... 详细信息

代码注释可以帮助开发人员理解代码的功能和实现方法。代码注释生成模型可以自动识别代码中的关键信息,并生成相关注释,提高代码的可读性和可维护性。现有的代码注释生成模型通常只使用抽象语法树结构信息来表示代码,导致模型生成注释质量不高。提出一种融合多结构信息的代码注释生成模型,该模型在代码抽象语法树的基础上,增加了数据流图结构信息来表示代码。模型使用transformer的编码器对抽象语法树序列进行编码,捕获代码全局信息。使用图神经网络对数据流图进行特征提取,提供变量之间的计算依赖关系等信息。然后使用跨模态注意力机制融合抽象语法树和数据流2种特征,经过transformer的解码器生成相应的注释。实验结果表明,与6种主流模型相比,所提出的模型在Java和Python数据集上的BlEU、METEOR和ROUGE-l指标得分均有提高,生成的注释也具有良好的可读性。

关键词：代码理解代码注释生成图神经网络多特征融合自然语言处理

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translating Pathological Brain Activity Primers in Parkinson’s Disease Research

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Research 2024年第1期2023卷 735-752页

作者： Daniela Mirzac Svenja l.Kreis Heiko J.luhmann Gabriel Gonzalez-Escamilla Sergiu Groppa Movement Disorders and Neurostimulation Department of NeurologyFocus Program Translational NeuroscienceRhine Main Neuroscience NetworkUniversity Medical Center of the Johannes Gutenberg University Mainz55131 MainzGermany Institute of Physiology University Medical Center of the Johannes Gutenberg University Mainz55131 MainzGermany

translational experimental approaches that help us better trace Parkinson’s disease(PD)pathophysiological mechanisms leading to new therapeutic targets are urgently *** this article,we review recent experimental and clinical studies addressing abnormal neuronal activity and pathological network oscillations,as well as their underlying mechanisms and *** aim is to enhance our knowledge about the progression of Parkinson's disease pathology and the timing of its symptom’s ***,we present mechanistic insights relevant for the generation of aberrant oscillatory activity within the cortico-basal ganglia *** summarize recent achievements extrapolated from available PD animal models,discuss their advantages and limitations,debate on their differential applicability,and suggest approaches for transferring knowledge on disease pathology into future research and clinical applications.

关键词： clinical knowledge insight

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Efficient fidelity estimation:alternative derivation and related applications

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Communications in Theoretical Physics 2024年第9期76卷 16-20页

作者： Diego S Starke Marcos l W Basso Jonas Maziero Physics Department Center for Natural and Exact SciencesFederal University of Santa MariaRoraima Avenue 1000Santa MariaRS97105-900Brazil Center for Natural and Human Sciences Federal University of ABCAvenue of the StatesSanto AndréSão Paulo09210-580Brazil

In[***.A 107012427(2023)],Baldwin and Jones prove that Uhlmann–Jozsa’s fidelity between two quantum statesρandσ,i.e.,F(ρ,σ)=(tr√√ρσ√ρ)^(2),can be written in a simplified form as F(ρ,σ)=(tr√ρσ)^(2).In this article,we give an alternative proof of this result,using a function power series expansion and the properties of the trace *** approach not only reinforces the validity of the simplified expression but also facilitates the exploration of novel dissimilarity functions for quantum states and more complex trace functions of density operators.

关键词： Ulhmann–Jozsa fidelity Rényi entropy efficient fidelity estimation Chebyshev polynomials

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Consensus controller for multi-UAV navigation

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Control Theory and Technology 2018年第2期16卷 110-121页

作者： Patrik KOlARIC ci CHEN Ankur DAlAl Frank l. lEWIS UTA Research Institute University of Texas at Arlington 7300 Jack Newell Bird S Fort Worth TX 76118 U.S.A. School of Automation Guangdong University of Technology Guangdong Key laboratory of loT Information Technology Guangzhou Guangzhou 510006 China State Key laboratory of Synthetical Automation for Process Industries Northeastern University Shenyang Liaoning 110819 China

In this paper, we design consensus algorithms for multiple unmanned aerial vehicles （UAV）. We mainly focus on the control design in the face of measurement noise and propose a position consensus controller based on the sliding mode control by using the distributed UAV information. Within the framework of lyapunov theory, it is shown that all signals in the closed-loop multi- UAV systems are stabilized by the proposed algorithm, while consensus errors are uniformly ultimately bounded. Moreover, for each local UAV, we propose a mechanism to define the trustworthiness, based on which the edge weights are tuned to eliminate negative influence from stubborn agents or agents exposed to extremely noisy measurement. Finally, we develop software for a nano UAV platform, based on which we implement our algorithms to address measurement noises in UAV flight tests. The experimental results validate the effectiveness of the proposed algorithms.

关键词： Consensus control multi-agent system quadrotor lyapunov stability distributed system

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Cylinder Pressure Prediction of An HCci Engine Using Deep learning

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Chinese Journal of Mechanical Engineering 2021年第2期34卷 160-167页

作者： Halit Yaşar GültekinÇağıl Orhan Torkul MerveŞişci Department of Mechanical Engineering Engineering FacultySakarya UniversityEsentepe Campus54187 SerdivanSakaryaTurkey Department of Industrial Engineering Engineering FacultySakarya UniversityEsentepe Campus54187 SerdivanSakaryaTurkey

Engine tests are both costly and time consuming in developing a new internal combustion ***,it is of great importance to predict engine characteristics with high accuracy using artificial ***,it is possible to reduce engine testing costs and speed up the engine development *** learning is an effective artificial intelligence method that shows high performance in many research areas through its ability to learn high-level hidden features in data *** present paper describes a method to predict the cylinder pressure of a Homogeneous Charge Compression Ignition(HCci)engine for various excess air coefficients by using Deep Neural Network,which is one of the Deep learning methods and is based on the Artificial Neural Network(ANN).The Deep learning results were compared with the ANN and experimental *** results show that the difference between experimental and the Deep Neural Network(DNN)results were less than 1%.The best results were obtained by Deep learning *** cylinder pressure was predicted with a maximum accuracy of 97.83%of the experimental value by using *** the other hand,the accuracy value was increased up to 99.84%using *** results show that the DNN method can be used effectively to predict cylinder pressures of internal combustion engines.

关键词： Artificial neural network Deep neural network HCci engine Cylinder pressure Excess air coefficient

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