检索结果-南通市图书馆

Simulation software and virtual environments for acceleration of agricultural robotics:Features highlights and performance comparison

引用

International Journal of Agricultural and Biological engineering 2018年第4期11卷 15-31页

作者： Redmond Ramin Shamshiri Ibrahim A.Hameed Lenka Pitonakova Cornelia Weltzien Siva K.Balasundram Ian J.Yule tony e.grift Girish Chowdhary Department of Agriculture Technology Faculty of AgricultureUniversiti Putra Malaysia43400SerdangSelangorMalaysia Dept.of ICT and Natural Sciences Faculty of Information Technology and Electrical EngineeringNorwegian University of Science and Technology(NTNU)Larsgårdsveien 2NO-6009ÅlesundNorway Department of Computer Science University of BristolBristolUnited Kingdom Leibniz Institute for Agricultural engineering and Bioeconomy Max-Eyth-Allee 10014469 Potsdam-BornimGermany New Zealand Centre for Precision Agriculture(NZCPA) School of Agriculture and EnvironmentMassey UniversityPrivate Bag 11222Palmerston North 4442New Zealand Department of Agricultural and Biological engineering University of Illinois at Urbana Champaign1304 West Pennsylvania Avenue UrbanaIL 61801USA

Research efforts for development of agricultural robots that can effectively perform tedious field tasks have grown significantly in the past *** robots are complex systems that require interdisciplinary collaborations between different research groups for effective task delivery in unstructured crops and plants *** the exception of milking robots,the extensive research works that have been carried out in the past two decades for adaptation of robotics in agriculture have not yielded a commercial product to *** accelerate this pace,simulation approach and evaluation methods in virtual environments can provide an affordable and reliable framework for experimenting with different sensing and acting mechanisms in order to verify the performance functionality of the robot in dynamic *** paper reviews several professional simulators and custom-built virtual environments that have been used for agricultural robotic *** key features and performance efficiency of three selected simulators were also compared.A simulation case study was demonstrated to highlight some of the powerful functionalities of the Virtual Robot experimentation *** of the objects and scenes were presented as the proof-of-concept for using a completely simulated robotic platform and sensing systems in a virtual citrus *** was shown that the simulated workspace can provide a configurable and modular prototype robotic system that is capable of adapting to several field conditions and tasks through easy testing and debugging of control algorithms with zero damage risk to the real robot and to the actual *** review suggests that an open-source software platform for agricultural robotics will significantly accelerate effective collaborations between different research groups for sharing existing workspaces,algorithms,and reusing the materials.

关键词： agricultural robotics precision agriculture virtual orchards digital agriculture simulation software multi-robots

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Research and development in agricultural robotics:A perspective of digital farming

引用

International Journal of Agricultural and Biological engineering 2018年第4期11卷 1-14页

作者： Redmond Ramin Shamshiri Cornelia Weltzien Ibrahim A.Hameed Ian J.Yule tony e.grift Siva K.Balasundram Lenka Pitonakova Desa Ahmad Girish Chowdhary Department of Agriculture Technology Faculty of AgricultureUniversiti Putra Malaysia43400SerdangSelangorMalaysia Leibniz Institute for Agricultural engineering and Bioeconomy Max-Eyth-Allee 10014469 Potsdam-BornimGermany Dept.of ICT and Natural Sciences Faculty of Information Technology and Electrical EngineeringNorwegian University of Science and Technology(NTNU)Larsgårdsveien 2NO-6009ÅlesundNorway New Zealand Centre for Precision Agriculture(NZCPA) School of Agriculture and EnvironmentMassey UniversityPrivate Bag 11222Palmerston North 4442New Zealand Department of Agricultural and Biological engineering University of Illinois at Urbana Champaign1304 West Pennsylvania Avenue UrbanaIL 61801USA Department of Computer Science University of BristolBristolUnited Kingdom Department of Biological and Agricultural engineering Faculty of EngineeringUniversiti Putra Malaysia

Digital farming is the practice of modern technologies such as sensors,robotics,and data analysis for shifting from tedious operations to continuously automated *** paper reviews some of the latest achievements in agricultural robotics,specifically those that are used for autonomous weed control,field scouting,and *** identification,task planning algorithms,digitalization and optimization of sensors are highlighted as some of the facing challenges in the context of digital *** concepts of multi-robots,human-robot collaboration,and environment reconstruction from aerial images and ground-based sensors for the creation of virtual farms were highlighted as some of the gateways of digital *** was shown that one of the trends and research focuses in agricultural field robotics is towards building a swarm of small scale robots and drones that collaborate together to optimize farming inputs and reveal denied or concealed *** the case of robotic harvesting,an autonomous framework with several simple axis manipulators can be faster and more efficient than the currently adapted professional expensive *** robots are becoming the inseparable parts of the modern farms,our conclusion is that it is not realistic to expect an entirely automated farming system in the future.

关键词： agricultural robotics precision agriculture virtual orchards digital agriculture simulation software multi-robots

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Dual ligand-targeted Pluronic P123 polymeric micelles enhance the therapeutic effect of breast cancer with bone metastases

引用

Oncology Research 2024年第4期32卷 769-784页

作者： HUAN GAO JIe ZHANG tony GKLeIJN ZHAOYONG WU BING LIU YUJIN MA BAOYUe DING DONGFeNG YIN Jiaxing Key Laboratory for Photonanomedicine and experimental Therapeutics Department of PharmaceuticsCollege of MedicineJiaxing UniversityJiaxing314001China Department of Pharmacy The General Hospital of Xinjiang Military RegionUrumqi830000China Department of Pathology and Medical Biology University Medical Center GroningenUniversity of GroningenGroningen9713 GZThe Netherlands Department of Pathology Laboratory of Experimental OncologyErasmus MCRotterdam3015 GDThe Netherlands Department of Pharmacy Jiaxing Maternal and Child Health Care HospitalAffiliated Hospital of Jiaxing UniversityJiaxing314001China Qinghai enlu Biotechnology Co. Ltd.Haidong810700China

Bone metastasis secondary to breast cancer negatively impacts patient quality of life and *** treatment of bone metastases is challenging since many anticancer drugs are not effectively delivered to the bone to exert a therapeutic *** improve the treatment efficacy,we developed Pluronic P123(P123)-based polymeric micelles dually decorated with alendronate(ALN)and cancer-specific phage protein DMPGTVLP(DP-8)for targeted drug delivery to breast cancer bone ***(DOX)was selected as the anticancer drug and was encapsulated into the hydrophobic core of the micelles with a high drug loading capacity(3.44%).The DOX-loaded polymeric micelles were spherical,123 nm in diameter on average,and exhibited a narrow size *** in vitro experiments demonstrated that a pH decrease from 7.4 to 5.0 markedly accelerated DOX *** micelles were well internalized by cultured breast cancer cells and the cell death rate of micelle-treated breast cancer cells was increased compared to that of free DOX-treated *** binding of the micelles to hydroxyapatite(HA)microparticles indicated their high affinity for bone.P123-ALN/DP-8@DOX inhibited tumor growth and reduced bone resorption in a 3D cancer bone metastasis *** vivo experiments using a breast cancer bone metastasis nude model demonstrated increased accumulation of the micelles in the tumor region and considerable antitumor activity with no organ-specific histological damage and minimal systemic *** conclusion,our study provided strong evidence that these pH-sensitive dual ligand-targeted polymeric micelles may be a successful treatment strategy for breast cancer bone metastasis.

关键词： Pluronic micelles Targeted nanotherapeutics Nanoparticulate drug delivery system Breast cancer with bone metastasis Therapeutic efficacy

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Functionalization of cellulose carbon dots with different elements(N,B and S)for mercury ion detection and anti-counterfeit applications

引用

Chinese Chemical Letters 2024年第7期35卷 355-359页

作者： Xiaoning Li Quanyu Shi Meng Li Ningxin Song Yumeng Xiao Huining Xiao tony D.James Lei Feng Second Affiliated Hospital of Dalian Medical University Dalian 116023China Hebei Key Lab of Power Plant Flue Gas Multi-Pollutants Control Department of Environmental Science and EngineeringNorth China Electric Power UniversityBaoding 071003China Department of Chemical engineering and Limerick Pulp&Paper Centre University of New Brunswick15 Dineen DriveFredericton NB E3B 5A3Canada Department of Chemistry University of BathBath BA27AYUnited Kingdom School of Chemistry and Chemical engineering Henan Normal UniversityXinxiang 453007China

Mercury ion(Hg^(2+)),as one of the most toxic heavy metal ions,accumulates easily in the environment,which can generate potential hazards to the ecosystem and human *** effectively detect and remove Hg^(2+),we fabricated four types of carbon dots(CDs)using carboxymethyl nanocellulose as a carbon source doped with different elements using a hydrothermal *** the CDs exhibited a strong fluorescence emission,excitation-dependent emission and possessed good water ***,the four fluorescent CDs were used for Hg^(2+)recognition in aqueous solution,where the CDs-N exhibited better sensitivity and selectivity for Hg^(2+)detection,with a low limit of detection of 8.29×10^(-6)mol/*** was determined that the fluorescence quenching could be ascribed to a photoinduced charge-transfer processes between Hg^(2+)and the *** addition,the CDs-N were used as a smart invisible ink for anticounterfeiting,information encryption and ***,the CDs-N were immersed into a cellulose(CMC)-based hydrogel network to prepare fluorescent hydrogels capable of simultaneously detecting and adsorbing Hg^(2+).We anticipate that this research will open possibilities for a green method to synthesize fluorescent CDs for metal ion detection and fluorescent ink production.

关键词： Carbon dots Functional groups Hg^(2+)detection Mechanism Anti-counterfeiting

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

An acoustofluidic device for the automated separation of platelet-reduced plasma from whole blood

引用

Microsystems & Nanoengineering 2024年第3期10卷 293-303页

作者： Zhehan Ma Jianping Xia Neil Upreti emeraghi David Joseph Rufo Yuyang Gu Kaichun Yang Shujie Yang Xiangchen Xu Jean Kwun eileen Chambers tony Jun Huang Thomas Lord Department of Mechanical engineering and Materials Science Duke UniversityDurhamNCUSA Department of Biomedical engineering Duke UniversityDurhamNCUSA Department of Pediatrics Duke UniversityDurhamNCUSA Duke Transplant Center Department of SurgeryDuke University School of MedicineDurhamNCUSA

Separating plasma from whole blood is an important sample processing technique required for fundamental biomedical research,medical diagnostics,and therapeutic *** protocols for plasma isolation require multiple centrifugation steps or multiunit microfluidic processing to sequentially remove large red blood cells(RBCs)and white blood cells(WBCs),followed by the removal of small ***,we present an acoustofluidic platform capable of efficiently removing RBCs,WBCs,and platelets from whole blood in a single *** leveraging differences in the acoustic impedances of fluids,our device generates significantly greater forces on suspended particles than conventional microfluidic approaches,enabling the removal of both large blood cells and smaller platelets in a single *** a result,undiluted human whole blood can be processed by our device to remove both blood cells and platelets(>90%)at low voltages(25 Vpp).The ability to successfully remove blood cells and platelets from plasma without altering the properties of the proteins and antibodies present creates numerous potential applications for our platform in biomedical research,as well as plasma-based diagnostics and ***,the microfluidic nature of our device offers advantages such as portability,cost efficiency,and the ability to process small-volume samples.

关键词： remove separation removing

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Diagnosis of CAH in a Sub Saharan Country: Visible Part of Iceberg

引用

Open Journal of Pediatrics 2024年第2期14卷 227-233页

作者： Suzanne Sap Ritha Mbono Hélène Kamo Jocelyn tony Charlotte eposse Jeannette epée Isabelle Mekone Adele Bodieu Gaelle Ntsoli Paul Olivier Koki Mother and Child Center of the Chantal Biya Foundation University of Yaoundé I Yaoundé Cameroon Laquintinie Hospital University of Douala Douala Cameroon Genral Hospital of Garoua University of Garoua Garoua Cameroon Human Reproductive Center and Research on Fertility of Yaoundé University of Yaoundé I Yaoundé Cameroon Yaounde General Hospital University of Yaoundé I Yaoundé Cameroon Yaounde Central Hospital Yaoundé Cameroon Laquintiinie Hospital Douala Cameroon

Introduction :Congenital adrenal hyperplasia (CAH) is the most common cause of primary adrenal insufficiency. It is a rare monogenic recessive disorder. In African setting in absence of neonatal screening, the diagnosis is still late, based on a clinical approach. During this clinical enquiry, information from past history or pedigree of the patient is of a huge importance and may revealed surprises. Patients and Methods: In this observational study, we retrospectively included all patients with a diagnosis of CAH. The diagnosis of CAH was retained based on a high 17 hydroxyprogesterone level in addition to clinical and morphological findings. From patients’ files, we extracted data on family history of disease, pedigree, clinical findings and genetics when available of 39 patients from two endocrinopeadiatric centers. Results: In 13 (30%) families, we found 20 reported deaths of infant less than 12 months. In these 13 families, half of the patients followed had 21 hydroxylase deficiencies and had 11 hydroxylase deficiencies. Unsurprisingly, we suspected adrenal insufficiency in these patients at verbal autopsy even in families with a patient with 11 hydroxylase deficiency. Other non DSD malformations or genetic disorders with apparently no link with CAH were reported in 3 families. The father of a patient reported to have hypospadias. Conclusion: each diagnosis of CAH made in our context is visible part of an iceberg. Behind a diagnosis of CAH made in our setting, is a long course of care, a dramatic past history revealing access to appropriate care disparity. Neonatal screening should thus be considered as an emergency.

关键词： Congenital Adrenal Hyperplasia

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Assessing parameter sensitivity in a university campus COVID-19 model with vaccinations

引用

Infectious Disease Modelling 2023年第2期8卷 374-389页

作者： Meghan Rowan Childs tony e.Wong Rochester Institute of Technology 1 Lomb Memorial DrRochesterNY14623USA

From the beginning of the COVID-19 pandemic,universities have experienced unique challenges due to their dual nature as a place of education and *** research has explored non-pharmaceutical approaches to combating COVID-19,including representing in models different categories such as age *** key area not currently well represented in models is the effect of pharmaceutical preventative measures,specifically vaccinations,on COVID-19 spread on college *** remain key questions on the sensitivity of COVID-19 infection rates on college campuses to potentially time-varying vaccine *** we introduce a compartment model that decomposes a campus population into constituent subpopulations and implements vaccinations with timevarying *** use this model to represent a campus population with both vaccinated and unvaccinated individuals,and we analyze this model using two metrics of interest:maximum isolation population and symptomatic *** demonstrate a decrease in symptomatic infections occurs for vaccinated individuals when the frequency of testing for unvaccinated individuals is *** find that the number of symptomatic infections is insensitive to the frequency of testing of the unvaccinated subpopulation once about 80%or more of the population is *** a Sobol’global sensitivity analysis,we characterize the sensitivity of modeled infection rates to these uncertain *** find that in order to manage symptomatic infections and the maximum isolation population campuses must minimize contact between infected and uninfected individuals,promote high vaccine protection at the beginning of the semester,and minimize the number of individuals developing symptoms.

关键词： COVID-19 Vaccination Subpopulation Modeling Sensitivity analysis University

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Acoustofluidics for simultaneous nanopartide-based drug loading and exosome encapsulation

引用

Microsystems & Nanoengineering 2022年第2期8卷 149-159页

作者： Zeyu Wang Joseph Rich Nanjing Hao Yuyang Gu Chuyi Chen Shujie Yang Peiran Zhang tony Jun Huang Department of Mechanical engineering and Materials Science Duke UniversityDurhamNC 27708USA Department of Biomedical engineering Duke UniversityDurhamNC 27708USA

Nanocarrier and exosome encapsulation has been found to significantly increase the efficacy of targeted drug delivery while also minimizing unwanted side ***,the development of exosome-encapsulated drug nanocarriers is limited by low drug loading efficiencies and/or complex,time-consuming drug loading ***,we have developed an acoustofluidic device that simultaneously performs both drug loading and exosome *** synergistically leveraging the acoustic radiation force,acoustic microstreaming,and shear stresses in a rotating droplet,the concentration,and fusion of exosomes,drugs,and porous silica nanoparticles is *** final product consists of drug-loaded silica nanocarriers that are encased within an exosomal *** drug loading efficiency is significantly improved,with nearly 30%of the free drug(e.g.,doxorubicin)molecules loaded into the ***,this acoustofluidic drug loading system circumvents the need for complex chemical modification,allowing drug loading and encapsulation to be completed within a matter of *** exosome-encapsulated nanocarriers exhibit excellent efficiency in intracellular transport and are capable of significantly inhibiting tumor cell *** utilizing physical forces to rapidly generate hybrid nanocarriers,this acoustofluidic drug loading platform wields the potential to significantly impact innovation in both drug delivery research and applications.

关键词： exosome loading simultaneous

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

extracellular vesicles:emerging tools as therapeutic agent carriers

引用

Acta Pharmaceutica Sinica B 2022年第10期12卷 3822-3842页

作者： Shan Liu Xue Wu Sutapa Chandra Christopher Lyon Bo Ning Li jiang Jia Fan tony Y.Hu Sichuan Provincial Key Laboratory for Human Disease Gene Study Department of Medical GeneticsDepartment of Laboratory MedicineSichuan Academy of Medical Sciences&Sichuan Provincial People’s HospitalChengdu 610072China Department of Biochemistry and Molecular Biology Center for Cellular and Molecular DiagnosisSchool of MedicineTulane UniversityNew OrleansLA 70112USA The M.O.e.Key Laboratory of Laboratory Medical Diagnostics the College of Laboratory MedicineChongqing Medical UniversityChongqing 400016China

extracellular vesicles(eVs)are secreted by both eukaryotes and prokaryotes,and are present in all biological fluids of vertebrates,where they transfer DNA,RNA,proteins,lipids,and metabolites from donor to recipient cells in cell-to-cell *** eV components can also indicate the type and biological status of their parent cells and serve as diagnostic targets for liquid *** can also natively carry or be modified to contain therapeutic agents(e.g.,nucleic acids,proteins,polysaccharides,and small molecules)by physical,chemical,or bioengineering *** to their excellent biocompatibility and stability,eVs are ideal nanocarriers for bioactive ingredients to induce signal transduction,immunoregulation,or other therapeutic effects,which can be targeted to specific cell ***,we review eV classification,intercellular communication,isolation,and characterization strategies as they apply to eV *** review focuses on recent advances in eV applications as therapeutic carriers from in vitro research towards in vivo animal models and early clinical applications,using representative examples in the fields of cancer chemotherapeutic drug,cancer vaccine,infectious disease vaccines,regenerative medicine and gene ***,we discuss current challenges for eV therapeutics and their future development.

关键词： extracellular vesicle Therapeutic agent Delivery carrier Outer membrane vesicle Cancer therapy Infectious disease vaccine Regenerative medicine Gene therapy

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Novel in-capsule synthesis of metal-organic framework for innovative carbon dioxide capture system

引用

Green energy & environment 2023年第3期8卷 767-774页

作者： Wei Yu Ming Gao Guanhe Rim tony G.Feric Mark L.Rivers Ammar Alahmed Aqil Jamal Ah-Hyung Alissa Park State Key Laboratory of Clean energy Utilization Zhejiang UniversityHangzhou310027China Lenfest Center for Sustainable energy The Earth InstituteColumbia University918 S.W.Mudd HallMail Code 4711500 W 120th St.New YorkNY10027USA Department of earth and environmental engineering 918 S.W.Mudd HallMail Code 4711500 W 120th St.New YorkNY10027USA Department of Chemical engineering Columbia UniversityNew YorkNY10027USA University of Chicago ChicagoIL60637USA Research and Development Center Saudi AramcoDhahran31311Saudi Arabia

Metal-Organic Frameworks(MOFs)have been developed as solid sorbents for CO_(2) capture applications and their properties can be controlled by tuning the chemical blocks of their crystalline units.A number of MOFs(e.g.,HKUST-1)have been developed but the question remains how to deploy them for gas-solid ***,the direct use of MOFs as nanocrystals would lead to serious problems and ***,for the first time,we report a novel MOF-based hybrid sorbent that is produced via an innovative in-situ microencapsulated *** a custom-made double capillary microfluidic assembly,double emulsions of the MOF precursor solutions and UV-curable silicone shell fluid are ***,HKUST-1 MOF is successfully synthesized within the droplets enclosed in the gas permeable *** developed MOF-bearing microcapsules uniquely allow the deployment of functional nanocrystals without the challenge of handling ultrafine particles,and further,can selectively reject undesired compounds to protect encapsulated MOFs.

关键词： encapsulation Metal-Organic Frameworks(MOFs) Carbon capture In-situ microencapsulated synthesis

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：