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Concentration-dependent effects of reductive pulmonary inhalants on ultrafine particle-induced oxidative stress:Insights for health risk assessment

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Environmental science and Ecotechnology 2024年第3期19卷 118-124页

作者： Ya-qi Yu tong Zhu BIC-EsAT and sKL-EsPC College of Environmental Sciences and EngineeringPeking UniversityBeijing100871PR China school of Environmental science and Engineering Qingdao UniversityQingdao266071PR China

The impact of reductive pulmonary inhalants on ultrafine particles(UFPs)-induced pulmonary oxidative stress remains a crucial consideration,yet the concentration-dependent effects of these inhalants have remained *** we s.nthesized composite UFPs simulating atmospheric UFPs,primarily composed of metals and *** subjected these UFPs to varying concentrations(0e7000 mM)of two reductive pulmonary inhalants.n-acetylcysteine and salbutamol,to assess their influence on oxidative potential,measured through the dithiothreitol assay(OP^(DTT)).simultaneously,we analysed the soluble metal content of UFPs to uncover potential relationships between oxidative potential and metal *** results unveil a dual role played by these inhalants in shaping the OPDTT of composite ***,OP^(DTT) generally increased as inhalant concentrations rose from 0 to 300 ***,an intriguing reversal occurred when concentrations exceeded 500 mM,resulting in a decline in *** to untreated UFPs,these inhalants induced promotion and inhibition effects within concentration ranges of 100e500 and>1000 mM,*** no significant correlation emerged between OP^(DTT) and soluble metal content as inhalant concentrations ranged from 0 to 7000 mM,noteworthy positive correlations emerged at lower inhalant concentrations(e.g.,n-acetylcysteine at 0 e300 mM).These findings provide insights into the potential influence of reductive pulmonary inhalants on health risks associated with UFP exposure,further underscoring the need for continued research in this critical area.

关键词： Concentration-dependent effects Oxidative potential Reductive pulmonary inhalants soluble metals simulated atmospheric ultrafine particles

The KAM theorem on the modulus of continuity about parameters

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science China Mathematics 2024年第3期67卷 577-592页

作者： Zhicheng tong Jiayin Du Yong Li school of Mathematics Jilin UniversityChangchun 130012China Institute of Mathematics Jilin UniversityChangchun 130012China school of Mathematics and statistics Center for Mathematics and Interdisciplinary SciencesNortheast Normal UniversityChangchun 130024China

In this paper,we study the Hamiltonian systems H(y,x,ξ,ε)=〈ω(ξ),y〉+εP(y,x,ξ,ε),where ω and P are continuous about ξ.We prove that persistent invariant tori possess the same frequency as the unperturbed tori,under a certain transversality condition and a weak convexity condition for the frequency mapping ω.As a direct application,we prove a Kolmogorov-Arnold-Moser(KAM) theorem when the perturbation P holds arbitrary Holder continuity with respect to the parameter ξ.The infinite-dimensional case is also *** our knowledge,this is the first approach to the systems with the only continuity in the parameter beyond H?lder's type.

关键词： Hamiltonian systems invariant tori frequency-preserving weak regularity

Weyl Type Theorem for Bounded Linear Operator and Its Functional Calculus

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Acta Mathematica s.nica,English series 2024年第2期40卷 528-536页

作者： Gao Hui Zi FEnG Peng tong LI school of Mathematics Nanjing University of Aeronautics and AstronauticsNanjing 210016P.R.China

Let H be a complex infinite dimensional Hilbert space and B(H)be the algebra of all bounded linear operators on *** this paper,we mainly study the operators that satisfy both a-Weyl's theorem and property(R).Also,the operators whose functional calculus satisfies the two properties are also *** give the features for the operator or its functional calculus for which both a-Weyl's theorem and property(R)hold.

关键词： a-Weyl's theorem property(R) functional calculus

s.nergistic governance:China's roadmap to improved health through climate and clean air actions

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Environmental science and Ecotechnology 2024年第4期20卷 14-15页

作者： Tao Xue tong Zhu Institute of Reproductive and Child Health National Health Commission Key Laboratory of Reproductive Health and Department of Epidemiology and BiostatisticsMinistry of Education Key Laboratory of Epidemiology of Major Diseases(PKU)School of Public HealthPeking University Health Science CentreBeijingChina sKL-EsPC and sEPKL-AERM College of Environmental Sciences and EngineeringCenter for Environment and HealthPeking UniversityBeijing100871China

The COP28's inaugural Health Day highlighted the growing recognition of the connection between climate and health,while China's state Council released its third air quality action plan aiming at ongoing health *** s.nergetic Roadmap project[1],which aims to track China's progress towards carbon neutrality and clean air,provides valuable insights to answer a set of intriguing questions concerning environmental health determinants,their source sectors,and the methods for harmonizing disparate actions to maximize health gain.

关键词： concerning neutral clean

A comprehensive review on microchannel heat s.nks for electronics cooling

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International Journal of Extreme Manufacturing 2024年第2期6卷 133-162页

作者： Zhi-Qiang Yu Mo-tong Li Bing-Yang Cao Key Laboratory for Thermal science and Power Engineering of Ministry of Education Department of Engineering MechanicsTsinghua UniversityBeijing 100084People’s Republic of China

The heat generation of electronic devices is increas.ng dramatically,which causes a serious bottleneck in the thermal management of electronics,and overheating will result in performance deterioration and even device *** the development of micro-machining technologies,the microchannel heat s.nk(MCHs)has become one of the best ways to remove the considerable amount of heat generated by high-power *** has the advantages of large specific surface area,small size,coolant saving and high heat transfer *** paper comprehensively takes an overview of the research progress in MCHss and generalizes the hotspots and bottlenecks of this *** heat transfer mechanisms and performances of different channel structures,coolants,channel materials and some other influencing factors are ***,this paper classifies the heat transfer enhancement technology and reviews the related studies on both the s.ngle-phase and phase-change flow and heat *** comprehensive review is expected to provide a theoretical reference and technical guidance for further research and application of MCHss in the future.

关键词： microchannel heat s.nk thermal management of electronics microscale heat transfer heat transfer enhancement

strategic Behavior Analysis and Modeling for Resilient Resource Allocation

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Journal of systems science and Information 2024年第3期12卷 340-359页

作者： tong LIU saike HE University of Chinese Academy of sciences Beijing 101408China China People's Police University Langfang 065000China state Key Laboratory of Multimodal Artificial Intelligence systems Institute of AutomationChinese Academy of SciencesBeijing 100190China

In an era where power systems face increased cyber threats,social media data,especially public s.ntiment during outages,emerges as a crucial component for devis.ng defense *** pres.nt a methodology that integrates s.ntiment analysis of social media data with advanced reinforcement learning techniques to tackle uncertain load redistribution *** approach first employs VADER and support Vector Machine(sVM)s.ntiment analysis on collected social media data,revealing insightful information about power outages and public *** Policy Optimization(PPO),a state-of-the-art reinforcement learning method,is then applied in the second stage to leverage these insights,manage outage uncertainty,and optimize defense *** efficacy of this methodology is demonstrated on a modified IEEE 6-bus *** results underscore our approach's effectiveness in utilizing social media data for a nuanced,targeted response to *** pioneering methodology offers a promis.ng direction for enhancing power grid resilience against cyberattacks and natural disasters,highlighting the value of social media s.ntiment analysis in power systems security.

关键词： disaster management load redistribution cyberattacks reinforcement learning s.ntiment analysis

Towards defining soil quality of Mediterranean calcareous agricultural soils:Reference values and potential core indicator set

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International soil and Water Conservation Research 2024年第1期12卷 145-155页

作者： Germán A.Durán Daniel sacristán Edelweis Farrús Jaume Vadell Institut de Recerca i FormacióAgrària i Pesquera de les Illes Balears C/Eusebi Estada14507009PalmaSpain Plant Biology Department University of Valencia46100BurjassotValenciaSpain soil and Environmental Quality Department Centro de Investigaciones sobre Desertificación-CIDE(CSIC-Universitat de València-Generalitat Valenciana)Carretera Moncada-Náquera km 4.546113MoncadaValenciaSpain Universitat de les Illes Balears Cra.De Valldemossakm 7507122PalmaSpain

To avoid soil degradation,adapt to climate change and comply with the sustainable Development goals 2030(Un General Assembly),establishing the quality/fertility of the agricultural soils of the Mediterranean region and evaluate how these evolve with time is *** enables adequate management practices to be *** Mediterranean calcareous region has received little attention in this s.nse,in spite its soil ***,24 different repres.ntative calcareous agricultural soils of the Mediterranean region,including the main management strategies of agricultural soils(rainfed and irrigated),were sampled from the island of Mallorca;and their physical,chemical and biological properties *** values obtained for most of the soil characteristics allowed to establish an initial approach to the reference values for the type of calcareous agricultural soils considered,and to clearly distinguish the effect of rainfed or irrigation management practices on soils properties and *** enzyme activities were not stimulated by the irrigation conditions assayed or they were only in dry conditions,suggesting optimum enzyme activities could be obtained when alternating dry and humid soil *** organic carbon,calcium carbonate and active lime revealed of significant importance in the collection of ***,the results obtained clearly indicate the heterogeneity of the region and its implications on the different soil ***,this study could serve as a starting point to adequately establish the quality(fertility)for Mediterranean calcareous agricultural soils and their reference values by conducting further research in this region and including more type of soils.

关键词： soil fertility Mediterranean agricultural soils Calcareous soils soil enzymes soil management

Early Phases of star Formation: Testing Chemical Tools

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Research in Astronomy and Astrophysics 2024年第1期24卷 96-118页

作者： n.C.Martinez s.Paron COnICET-Universidad de Buenos Aires.Instituto de Astronomía y Física del Espacio Ciudad Universitaria(C1428EGA)Ciudad Autónoma de Buenos AiresArgentina

star-forming processes strongly influence the IsM ***,many high-quality databases are available at millimeter *** them,it is possible to carry out studies that review and deepen previous *** these studies involve large samples of sources,it is preferred to use direct tools to study the molecular *** the aim of testing these tools such as the use of the HCn/HnC ratio as a thermometer,and the use of H^(13)CO^(+),HC_(3)n,n_(2)H^(+) and C_(2)H as "chemical clocks," we pres.nt a molecular line study toward 55 sources repres.nting massive young stellar objects at different evolutionary stages:infrared dark clouds(IRDCs),highmass protostellar objects(HMPOs),hot molecular cores(HMCs) and ultracompact H II *** found that the use of the HCn/HnC ratio as a universal thermometer in the IsM should be taken with care because the HCn optical depth is a big issue that can affect the ***,this tool should be utilized only after a careful analysis of the HCn spectrum,checking that no line,neither the main nor the hyperfine ones,pres.nts absorption *** point out that the analysis of the emission of H^(13)CO^(+),HC_(3)n,n_(2)H^(+) and C_(2)H could be useful to trace and distinguish regions among IRDCs,HMPOs and *** molecular line widths of these four species increase from the IRDC to the HMC stage,which can be a consequence of the gas dynamics related to the starforming processes taking place in the molecular *** results.not only contribute with more statistics,acting as a probe of such chemical tools,useful to obtain information in large samples of sources,but also complement previous works through the analysis of other types of sources.

关键词： stars:formation IsM:molecules IsM:clouds

d-Orbital steered Fen_(4)moiety through n,s dual-site adjustation for zinc-air flow battery

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Journal of Energy Chemistry 2024年第5期92卷 8-15页

作者： Chunzhu Bao Mingwei tong Xueli Li Zhonghua Xiang state Key Laboratory of Organic-Inorganic Composites Beijing University of Chemical TechnologyBeijing 100029China

The implementation of pristine covalent organic polymer(CO_(2)P)with well-defined structure as air electrode may spark fresh vitality to rechargeable zinc-air flow batteries(ZAFBs),but it still remains challenges in s.nergistically regulating their electronic states and structural porosity for the great device ***,we conquer these issues by exploiting n and s co-doped graphene with COP rich in metal-ligand nitrogen to s.nergistically construct an effective catalyst for oxygen reduction reaction(ORR).Among them,the n and s co-doped sites with high electronegativity properties alter the number of electron occupations in the d orbital of the iron centre and form electron-transfer bridges,thereby boosting the selectivity of the ORR-catalysed four-electron ***,the introduction of COP materials aids the formation of pore interstices in the graphene lamellae,which both adequately expose the active sites and facilitate the transport of reactive *** from the s.nergistic effect,as-prepared catalyst exhibits excellent half-wave potentials(E_(1/2)=912 mV)and stability(merely 8.8%drop after a long-term durability test of 50000 s).Further,ZAFBs assembled with the n/sG@CO_(2)P catalyst demonstrate exceptional power density(163.8 mW cm^(-2))and continuous charge and discharge for approximately 140 h at 10 mA cm^(-2),outperforming the noble-metal benchmarks.

关键词： nitrogen/sulfurdual sites Metal-coordinated nitrogen sites Covalent organic polymer Oxygen reduction reaction Zn-airflow battery