检索结果-南通市图书馆

Brain activation induced by different strengths of hand grasp: a functional magnetic resonance imaging study

Neural Regeneration Research 2020年第5期15卷 875-879页

作者： Hyeok Gyu kwon Ju Sang kim Mi Young Lee Department of Physical Therapy College of Health ScienceEulji UniversityGyeonggiRepublic of Korea Department of Physical Therapy and Rehabilitation Yeungnam University HospitalDaeguRepublic of Korea Department of Physical Therapy College of Health and TherapyDaegu Haany UniversityGyeongsansiRepublic of Korea

Mirror neuron system can be activated by observation and execution of an *** has an important function of action *** investigated brain activations in humans by observing the strength of a hand grasp using functional magnetic resonance *** right-handed healthy individuals,consisting of 10 males and 10 females,aged 22.40 ± 2.04 years,were recruited into this study from September to November 2017 via *** hand grasp task video showed a hand lightly grasping and releasing a ball *** hand grasp task video showed a hand tightly grasping and releasing a ball *** magnetic resonance imaging block design paradigm comprised five stimulation blocks alternating with five baseline *** blocks were presented with two stimulus tasks,consisting of a light grasp and a powerful *** of interest was defined around the inferior parietal lobule,inferior frontal gyrus,and superior temporal sulcus which have been called mirror neuron *** inferior parietal lobule,fusiform,postcentral,occipital,temporal,and frontal gyri were activated during light and powerful grasp *** BOLD signal response of a powerful grasp was stronger than that of a light *** results suggest that brain activation of the inferior parietal lobule,which is the core brain region of the mirror neuron system,was stronger in the powerful grasp task than in the light grasp *** believe that our results might be helpful for instructing rehabilitation of brain *** study was approved by the Institutional Review Board of Daegu Oriental Hospital of Daegu Haany University on September 8,2017 (approval ***-D-17020-PRO-01).

关键词： brain activation fMRI human brain inferior parietal lobule light grasp mirror neuron system powerful grasp

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Fracture Characteristics of Frit Bonding through In-Situ Nano-Indentation Testing

引用

Journal of Materials Science & Technology 2016年第11期32卷 1204-1210页

作者： Won Je Jo Hee-Jun Ahn Jong Hyoung kim Dongil kwon Department of Materials Science and Engineering Seoul National University

Because frit bonding material is brittle, sudden impacts such as dropping may damage the bonding significantly. Strain-rate-controlled in-situ nano-indentation testing, which can determine localized material properties, was carried out on the frit-bonded specimen, especially on the frit bonding matrix and the filler. The results were compared with the drop-impact fracture behavior to understand the fracture characteristics. Mechanical properties at static condition or low strain rate did not show proper relationship with the fracture tendency of the drop tested result of the frit bonding. From the relationship between fracture toughness and the ratio of modulus/hardness, fracture characteristics at the drop impact situation could be estimated by the values at the high strain rate nano-indentation. The ratio between modulus and hardness on frit matrix showed close relationship with drop impact fracture. Though crack propagation path deflected at filler interface, filler property gave less influence on fracture tendency of drop impact fracture due to its small volume fraction. The properties of frit matrix were crucial to the fracture characteristics of the frit bonding.

关键词： Nanoindentation Bonding Fracture behavior

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

EAFoC： Enterprise Architecture Framework Based on Commonality

引用

Journal of Computer Science & Technology 2006年第6期21卷 952-964页

作者： Jin-Woo kim Ju-Hum Kwo Young-Gab kim Chee-Yang Song Hyun-Seok kim Doo-kwon Baik Department of Computer Science and Engineering Korea University 1 5-Ga Anam-Dong Sungbuk-Ku Seoul 136-701 Korea Department of Software Engineering Sang-Ju National University 386 Street Kajang-Dong Sang-Ju 742-711 Korea

The recent rapid development in information systems （ISs） has resulted in a critical need for integration and interoperability between heterogeneous ISs in various domains, using specific commonalities. However, stovepipe systems have been caused due to inconsistencies in planning IS architecture among stakeholders. So far, there has been no research on an enterprise architecture framework （EAF） that can satisfy with the coefficient factors of system architecture （SA） and enterprise architecture （EA）. This paper proposes a new EAF that can resolve the problems inherent in existing legacy EAFs and their features. EAFoC （Enterprise Architecture Framework based on Commonality） is based on commonality that can be satisfied as the coefficient factors in both SA and EA within a common information technology （IT） domain. Thus, it should be possible to integrate an established heterogeneous framework for each stakeholder＇s view. Consequently, the most important contribution of this paper is to establish the appropriate EAFoC for the development of consistent IS architecture, smooth communication among stakeholders, systematic integration management of diversified and complicated new IT technologies, interoperability among heterogeneous ISs, and reusability based on commonality with other platforms.

关键词： enterprise architecture (EA) enterprise architecture framework based on commonality (EAFoC) enterprise integration (El) requirements engineering process system architecture (SA)

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Distribution of electric field for carbon nanotube assembly: Experiments (II)

引用

Transactions of Nonferrous Metals Society of China 2011年第A1期21卷 121-125页

作者： Soongeun kwon Soo-Hyun kim Kwang-ho kim Myung-chang KANG Hyung-woo LEE Department of Mechanical Engineering Korea Advanced Institute of Science and Technology (KAIST) Daejeon 305-701 Korea National Core Research Center for Hybrid Materials Solution Pusan National University

The distribution effect of electric field on the alignment and attachment of carbon nanotubes （CNTs） were investigated. The experimental results were compared with the simulation results according to three different shaped electrodes. In previous simulation, the round shaped electrodes were expected to be more effective for aligning and attaching a single CNT between two electrodes than conical or rectangular shaped electrodes. To verify the simulation results, three different shaped electrodes were introduced and a single multi-walled carbon nanotube （MWNT） was attached. The optimal conditions for aligning and attaching MWNTs such as the frequency, applied voltage and concentration of MWNTs solution were investigated. Through repeated experiments, frequency of 100 kHz-10 MHz, applied voltage of 0.3-1.3 V^s/~m, concentration of 5 ktg/mL in MWNTs solution were obtained as a possible condition range to attach MWNTs. Under these conditions, the yield of MWNTs attachment between two electrodes was up to 70%. In previous simulation, furthermore, it was verified that the size of the stable or quasi-stable region made CNTs aligned and attached on different shaped electrodes from the comparison of the experimental and simulation results. Most single MWNT attachment was accomplished on the round shaped electrodes.

关键词： carbon nanotubes dielectrophoresis round shaped electrode simulation

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

A metallic anti-biofouling surface with a hierarchical topography containing nanostructures on curved micro-riblets

引用

Microsystems & Nanoengineering 2022年第1期8卷 83-96页

作者： Taekyung kim Sunmok kwon Jeehyeon Lee Joon Sang Lee Shinill Kang National Center for Optically-assisted high precision Mechanical Systems Yonsei UniversitySeoul 03722Korea School of Mechanical Engineering Yonsei University50 Yonsei-roSeodaemun-guSeoul 03722Korea

Metallic surface finishes have been used in the anti-biofouling,but it is very difficult to produce surfaces with hierarchically ordered *** the present study,anti-biofouling metallic surfaces with nanostructures superimposed on curved micro-riblets were produced via top-down *** to the attachment theory,these surfaces feature few attachment points for organisms,the nanostructures prevent the attachment of bacteria and algal zoospores,while the micro-riblets prohibit the settlement of *** oxidation was performed to induce *** forms a hydration layer on the surface,which physically blocks foulant adsorption along with the anti-biofouling *** characterized the surfaces via scanning electron and atomic force microscopy,contact-angle measurement,and wear-resistance *** contact angle of the hierarchical structures was less than 1°.Laboratory settlement assays verified that bacterial attachment was dramatically reduced by the nanostructures and/or the hydration layer,attributable to *** micro-riblets prohibited the settlement of *** 77 days of static immersion in the sea during summer,the metallic surface showed significantly less biofouling compared to a surface painted with an anticorrosive coating.

关键词： Anti-biofouling Superhydrophilic Hierarchical topography Metallic engineered surface Nanoimprinting,static immersion test,field trials

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Coastal landscape evolution tracked from late Holocene wave-cut benches in the Sinan Archipelago,Southwest Korea

引用

Geoscience Frontiers 2020年第1期11卷 293-301页

作者： Sung-Ja Choi Bokchul kim Yong Sik Gihm Sanghoon kwon Geology Division Korea Institute of Geoscience and Mineral ResourcesDaejeon34132Republic of Korea Department of Earth System Sciences Yonsei UniversitySeoul03722Republic of Korea School of Earth Sciences The Ohio State UniversityColumbusOH43210USA

Glacio-isostatic adjustment(GIA)and tectonic activity are important factors in the formation of marine *** Holocene wave-cut benches in the eastern part of the West Sea of Korea,also called the Yellow Sea,can be divided into two steps:531 cm above sea level(ASL)for the upper bench(T2)and 464-481 cm ASL for the lower bench(T1).Sediments on the benches a re classified into four units,and are interpreted to be beach deposits acco rding to gravel shape,textu re,and seaward *** ove rlying sediment indicates that T2 was formed at approximately 530 cm ASL before 2900 yr BP,and T1 at approximately 460-480 cm ASL before 1520 yr *** Holocene(4000-2000 yr BP)relative sea level(RSL)curves based on GIA models are inconsistent with the wave-cut bench *** T1 and T2 benches to the RSL curves of the West Sea,the upper and the lower benches were uplifted by approximately 5-8 m and 4-7 m,*** the area is several hundred kilometers away from plate boundaries,the high frequency of earthquakes in the West Sea may have induced the uplift of wave-cut benches during the last 2000 *** indicate that the west coast of the Korean Peninsula(KP)should no longer be considered an area of subsidence,but be assigned to a regime of uplift during the late Holocene.

关键词： West Sea of Korea Yellow Sea Late Holocene Wave-cut benches Beach sediment Uplift Tectonics

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Effectiveness of gastric cancer screening programs in South Korea:Organized vs opportunistic models

引用

World Journal of Gastroenterology 2013年第5期19卷 736-741页

作者： Beom Jin kim Chae Heo Byoung kwon kim Jae Yeol kim Jae Gyu kim Department of Internal Medicine Chung-Ang University College of MedicineHeukseok-dongDongjak-guSeoul 156-755South Korea Department of Pathology Green Cross Reference Laboratory314 Pojung-dongGiheung-guYongin-siKyunggi-do 446-913South Korea

AIM:To investigate the outcome and effectiveness of two screening programs,National Cancer Screening Program(NCSP)and opportunistic screening(OS),for the detection of gastric cancer. METHODS:A total of 45 654 subjects underwent upper endoscopy as part of the NCSP or OS at the Chung-Ang University Healthcare System in Korea between January 2007 and December *** study population was comprised of subjects over the age of 40 *** specifically,subjects who took part in the NCSP were Medicaid recipients and beneficiaries of the National Health Insurance *** photo-graphs from the endoscopies diagnosed as gastric cancer were reviewed by two experienced endoscopists. RESULTS:The mean age of the screened subjects was 55 years for men and 54 years for women.A total of 126 cases(0.28%)of gastric cancer were detected from both screening programs;100 cases(0.3%)from NCSP and in 26 cases(0.2%)from *** proportion of early gastric cancer(EGC)detected in NCSP was higher than that in OS(74.0%vs 53.8%,P=0.046). Among the 34 416 screenees in NCSP,6585(19.1%) underwent upper endoscopy every other year as *** the 11 238 screenees in OS,3050(27.1%) underwent upper endoscopy at least once every two years during the study *** detection rate of gastric cancer was found to be significantly higher during irregular follow-up than during regular follow-up in both screening programs(0.3%vs 0.2%,P=0.036).A higher incidence of EGC than advanced gastric cancer was observed during regular follow-up compared with irregular follow-up. CONCLUSION:Compliance to the screening program is more important than the type of screening system used.

关键词： Gastric cancer National Cancer Screening Program Opportunistic screening Early gastric cancer

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

How has the disease course of pediatric ulcerative colitis changed throughout the biologics era?A comparison with the IBSEN study

引用

World Journal of Gastroenterology 2022年第28期28卷 3666-3681页

作者： Yiyoung kwon Eun Sil kim Yon Ho Choe Mi Jin kim Department of Pediatrics Samsung Medical CenterSeoul 06351South Korea Department of Pediatrics Kangbuk Samsung Medical CenterSeoul 03181South Korea

BACKGROUND In Korea,infliximab was approved for use in children with ulcerative colitis(UC)in October *** To compare the clinical course of UC before and after the introduction of biological agents,and to compare with the IBSEN *** Patients under 18 years of age,who were diagnosed with UC and followed from January 2003 to October 2020,were included in the *** A(n=48)was followed for at least 2 years between January 2003 and October 2012,and Group B(n=62)was followed for at least 2 years between November 2012 and October *** compared endoscopic remission,drug composition,relapse rate,steroidfree period,and the quality of life of each *** plotted the clinical course of the included patients using the pediatric UC activity index score,and compared our patients with those in the IBSEN *** After 2 years of treatment,colonoscopy evaluation revealed different outcomes in the two treatment *** was confirmed in 14 patients(29.2%)of Group A,and in 31 patients(50.0%)of Group B(P<0.012).The median cumulative corticosteroid-free period was 3.0 years in Group A and 4.4 years in Group ***-free period of Group B was significantly longer than that of Group A(P<0.001).There was a statistically significant difference between the two groups in evaluation of the relapse rate during the observation period(P<0.001).The plotted clinical course graphs of Group A showed similar proportions to the graphs in the IBSEN ***,in Group B,the proportion of patients corresponding to curve 1(remission or mild severity after initial high activity)was high at 76%(47/62).CONCLUSION The incidence of relapse has decreased and the steroid-free period has increased after the introduction of the biological *** clinical course also showed a different pattern from that of IBSEN *** active use of biological agents may change the long-term disease course in moderate to severe pediatric UC.

关键词： Colitis Ulcerative Children Infliximab Relapse Steroid

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Deep learning-based virtual staining,segmentation,and classification in label-free photoacoustic histology of human specimens

引用

Light(Science & Applications) 2024年第10期13卷 2353-2366页

作者： Chiho Yoon Eunwoo Park Sampa Misra Jin Young kim Jin Woo Baik Kwang Gi kim Chan kwon Jung Chulhong kim Departments of Electrical Engineering Convergence IT EngineeringMechanical EngineeringMedical Science and EngineeringGraduate School of Artificial Intelligenceand Medical Device Innovation CenterPohang University of Science and Technology(POSTECH)PohangRepublic of Korea Opticho Inc. PohangRepublic of Korea Department of Health Sciences and Technology Gachon Advanced Institute for Health Sciences and Technology(GAIHST)Gachon UniversityIncheonRepublic of Korea Cancer Research Institute College of MedicineThe Catholic University of KoreaSeoulRepublic of Korea Department of Hospital Pathology Seoul St.Mary’s HospitalCollege of MedicineThe Catholic University of KoreaSeoulRepublic of Korea

In pathological diagnostics,histological images highlight the oncological features of excised specimens,but they require laborious and costly staining *** recent innovations in label-free microscopy that simplify complex staining procedures,technical limitations and inadequate histological visualization are still problems in clinical ***,we demonstrate an interconnected deep learning(DL)-based framework for performing automated virtual staining,segmentation,and classification in label-free photoacoustic histology(PAH)of human *** framework comprises three components:(1)an explainable contrastive unpaired translation(E-CUT)method for virtual H&E(VHE)staining,(2)an U-net architecture for feature segmentation,and(3)a DL-based stepwise feature fusion method(StepFF)for *** framework demonstrates promising performance at each step of its application to human liver *** virtual staining,the E-CUT preserves the morphological aspects of the cell nucleus and cytoplasm,making VHE images highly similar to real H&E *** segmentation,various features(e.g.,the cell area,number of cells,and the distance between cell nuclei)have been successfully segmented in VHE ***,by using deep feature vectors from PAH,VHE,and segmented images,StepFF has achieved a 98.00%classification accuracy,compared to the 94.80%accuracy of conventional PAH *** particular,StepFF’s classification reached a sensitivity of 100%based on the evaluation of three pathologists,demonstrating its applicability in real clinical *** series of DL methods for label-free PAH has great potential as a practical clinical strategy for digital pathology.

关键词： stepwise Deep spite

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Regeneration-associated macrophages： a novel approach to boost intrinsic regenerative capacity for axon regeneration

引用

Neural Regeneration Research 2016年第9期11卷 1368-1371页

作者： Min Jung kwon Hyuk Jun Yoon Byung Gon kim Department of Brain Science Ajou University School of Medicine Suwon Republic of Korea Department of Neurology Ajou University School of Medicine Suwon Republic of Korea Neuroscience Graduate Program Department of Biomedical Sciences Ajou University Graduate School of Medicine Suwon Republic of Korea

Axons in central nervous system （CNS） do not regenerate spontaneously after injuries such as stroke and traumatic spinal cord iniury. Both intrinsic and extrinsic factors are responsible for the regeneration fail- ure, Although intensive research efforts have been invested on extrinsic regeneration inhibitors, the extent to which glial inhibitors contribute to the regeneration failure in viva still remains elusive. Recent exper- imental evidence has rekindled interests in intrinsic factors for the regulation of regeneration capacity in adult mammals. In this review, we propose that activating macrophages with pro-regenerative molecular signatures could be a novel approach for boosting intrinsic regenerative capacity of CNS neurons. Using a conditioning injury model in which regeneration of central branches of dorsal root ganglia sensory neu- rons is enhanced by a preceding injury to the peripheral branches, we have demonstrated that perineuronal macrophages surrounding dorsal root ganglia neurons are critically involved in the maintenance of en- hanced regeneration capacity. Neuron-derived chemokine （C-C motif） ligand 2 （CCL2） seems to mediate neuron-macrophage interactions conveying injury signals to perineuronal macrophages taking on a soley pro-regenerative phenotype, which we designate as regeneration-associated macrophages （RAMs）. Ma- nipulation of the CCL2 signaling could boost regeneration potential mimicking the conditioning injury, suggesting that the chemokine-mediated RAM activation could be utilized as a regenerative therapeutic strategy for CNS injuries.

关键词： axon regeneration conditioning injury neuron-macrophage interaction regeneration-associatedmacrophage cAMP CCL2 M2 polarization spinal cord injury

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：