Brain activation induced by different strengths of hand grasp: a functional magnetic resonance imaging study

作     者：Hyeok Gyu Kwon Ju Sang Kim Mi Young Lee Hyeok Gyu Kwon;Ju Sang Kim;Mi Young Lee

作者机构：Department of Physical TherapyCollege of Health ScienceEulji UniversityGyeonggiRepublic of Korea Department of Physical Therapy and RehabilitationYeungnam University HospitalDaeguRepublic of Korea Department of Physical TherapyCollege of Health and TherapyDaegu Haany UniversityGyeongsansiRepublic of Korea 

出 版 物：《Neural Regeneration Research》 (中国神经再生研究（英文版）)

年 卷 期：2020年第15卷第5期

页      面：875-879页

核心收录：

学科分类：0710[理学-生物学] 0831[工学-生物医学工程（可授工学、理学、医学学位）] 100207[医学-影像医学与核医学] 1002[医学-临床医学] 1001[医学-基础医学(可授医学、理学学位)] 08[工学] 1010[医学-医学技术（可授医学、理学学位）] 100204[医学-神经病学] 10[医学] 

基　　金：supported by the Basic Science Research Program through the National Research Foundation of Korea(NRF) funded by the Ministry of Education(No.2017R1D1A1B03033985 to MYL) the National Research Foundation of Korea(NRF) grant funded by the Korea government(MSIT)(No.2018R1A5A2025272 to MYL) 

主　　题：brain activation fMRI human brain inferior parietal lobule light grasp mirror neuron system powerful grasp 

摘      要：Mirror neuron system can be activated by observation and execution of an *** has an important function of action *** investigated brain activations in humans by observing the strength of a hand grasp using functional magnetic resonance *** right-handed healthy individuals,consisting of 10 males and 10 females,aged 22.40 ± 2.04 years,were recruited into this study from September to November 2017 via *** hand grasp task video showed a hand lightly grasping and releasing a ball *** hand grasp task video showed a hand tightly grasping and releasing a ball *** magnetic resonance imaging block design paradigm comprised five stimulation blocks alternating with five baseline *** blocks were presented with two stimulus tasks,consisting of a light grasp and a powerful *** of interest was defined around the inferior parietal lobule,inferior frontal gyrus,and superior temporal sulcus which have been called mirror neuron *** inferior parietal lobule,fusiform,postcentral,occipital,temporal,and frontal gyri were activated during light and powerful grasp *** BOLD signal response of a powerful grasp was stronger than that of a light *** results suggest that brain activation of the inferior parietal lobule,which is the core brain region of the mirror neuron system,was stronger in the powerful grasp task than in the light grasp *** believe that our results might be helpful for instructing rehabilitation of brain *** study was approved by the Institutional Review Board of Daegu Oriental Hospital of Daegu Haany University on September 8,2017 (approval ***-D-17020-PRO-01).