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检索条件"作者=Tomi Pastinen"
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Asthma-associated polymorphisms in 17q12-21 locus modulate methylation and gene expression of GSDMA in naive CD4^+ T cells
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Journal of Genetics and Genomics 2020年 第3期47卷 171-174页
作者: Anne-Marie Madore Lucile Pain Anne-Marie Boucher-Lafleur Andréanne Morin Jolyane Meloche Marie-Michelle Simon Bing Ge Tony Kwan Warren A.Cheung tomi pastinen Catherine Laprise Departement des sciences fondamentales Universite du Quebec a ChicoutimiSaguenayQuebecG7H 2B1Canada Department of Human Genetics McGill UniversityMontrealQuebecH3A 0C7Canada Department of Human Genetics University of ChicagoIL60637USA McGill University and Genome Quebec Innovation Centre MontrealQuebecH3A 0G1Canada Center for Pediatric Genomic Medicine Kansas CityMO64108USA Centre intersectoriel en sante durable Universite du Quebec a ChicoutimiSaguenayQuebecG7H 2B1Canada
The 17q12-21 locus harboring ORMDL sphingolipid biosynthesis regulator 3(ORMDL3)and Gasdermin B(GSDMB)genes exhibits one of the most significant and replicated associations with asthma[MIM:600807](Stein et al.,2018).S... 详细信息
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