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2024 Wheelchair Compendium of Physical Activities:An update of activity codes and energy expenditure values

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Journal of sport and Health science 2024年第1期13卷 18-23页

作者： scott A.Conger stephen D.Herrmann Erik A.Willis tom E.Nightingale Joseph R.sherman Barbara E.Ainsworth Department of Kinesiology Boise State UniversityBoiseID 83725USA Kansas Center for Metabolism and Obesity Research The University of Kansas Medical CenterKansas CityKS 66160USA Center for Health Promotion and Disease Prevention University of North Carolina at Chapel HillChapel HillNC 27599USA school of sport Exercise and Rehabilitation SciencesUniversity of BirminghamBirmingham AL B152TTUK Centre for Trauma sciences Research University of BirminghamEdgbastonBirmingham AL B152TTUK College of Health solutions Arizona State UniversityPhoenixAZ 85003USA school of Exercise and Health Shanghai University of SportShanghai 200438China

Purpose:This paper presents an update of the 2011 Wheelchair Compendium of Physical Activities designed for wheelchair users and is referred to as the 2024 Wheelchair *** Wheelchair Compendium aims to curate existing knowledge of the energy expenditure for wheelchair physical activities(PAs).Methods:A systematic review of the published energy expenditure of PA for wheelchair users was completed between 2011 and May *** added these data to the 2011 Wheelchair Compendium data that was compiled previously in a systematic review through ***:A total of 47 studies were included,and 124 different wheelchair PA reported energy expenditure values ranging from 0.8 metabolic equivalents for wheelchair users(filing papers,light effort)to 11.8 metabolic equivalents for wheelchair users(Nordic sit skiing).Conclusion:In introducing the updated 2024 Wheelchair Compendium,we hope to bridge the resource gap and challenge the prevailing narratives that inadvertently exclude wheelchair users from physical fitness and health PAs.

关键词： Disability Exercise MET Mobility

Expanding catalytic promiscuity of a bifunctional terpene synthase through a single mutation-induced change in hydrogen-bond network within the catalytic pocket

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synthetic and systems Biotechnology 2024年第2期9卷 380-387页

作者： Xinye Wang Yiyi Huang Weiyan Zhang Kangjie Lv Xiaoying Li Zhixin Wang Li Zhang tom Hsiang Lixin Zhang Liming Ouyang Xueting Liu state Key Laboratory of Bioreactor Engineering East China University of Science and TechnologyShanghai200237China Department of Chemistry Boston UniversityBostonMAUSA school of Environmental sciences University of Guelph50 Stone Road EastGuelphOntarioN1G 2W1Canada

Fungal bifunctional terpene synthases(BFTss)catalyze the formation of numerous di-/sester-/tri-terpenes ***,the mechanism in controlling the cyclization pattern of terpene scaffolds is rarely deciphered for further application of tuning the catalytic promiscuity of terpene synthases for expanding the chemical *** this study,we expanded the catalytic promiscuity of Fusarium oxysporum fusoxypene synthase(FoFs)by a single mutation at L89,leading to the production of three new *** computational analysis revealed that the reconstitution of the hydrogen-bond(H-bond)network of second-shell residues around the active site of FoFs influences the orientation of the aromatic residue W69 within the first-shell catalytic ***,the dynamic orientation of W69 alters the carbocation transport,leading to the production of diverse ring system *** findings enhance our knowledge on understanding the molecular mechanisms,which could be applied on protein engineering terpene synthases on regulating the terpene skeletons.

关键词： Bifunctional terpene synthase sesterterpene Carbocation transportation Density functional theory calculations Molecular dynamics simulations

Inbreeding and genetic load in a pair of sibling grouse species:Tetrastes sewersowi and ***

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Avian Research 2024年第2期15卷 265-270页

作者： Kai song tom van der Valk Bin Gao Peter Halvarsson Yun Fang Wendong Xie siegfried Klaus Zhiming Han Yue-Hua sun Jacob Hoglund Key Laboratory of Animal Ecology and Conservation Biology Institute of ZoologyChinese Academy of SciencesBeijing100101China Animal Ecology Department of Ecology and GeneticsUppsala UniversityNorbyvagen 18DUppsala75236Sweden Department of Cell and Molecular Biology Uppsala75273Sweden Unit of Parasitology Department of Biomedicine and Veterinary Public HealthSwedish University of Agricultural SciencesPO Box 7036Uppsala75007Sweden Lindenhohe 5 JenaD-07749Germany The state Key Laboratory of Reproductive Biology Institute of ZoologyChinese Academy of SciencesBeijing100101China

Genetic load and inbreeding are recognized as important factors to be considered in conservation *** levels of both can increase the risk of population extinction by negatively impacting fitness-related characters in many species of plants and animals,including humans(inbreeding depression).Genomic tech-niques are increasingly used in measuring and understanding genetic load and inbreeding and their importance in evolution and *** used whole genome resequencing data from two sibling grouse species in subarctic Eurasia to quantify *** found a large range of inbreeding measured as FROH(fraction of runs of homozygosity)in individuals from different populations of Chinese Grouse(Tetrastes sewerzowi)and Hazel Grouse(***).FROH estimated from genome-wide runs of homozygosity(ROH)ranged from 0.02 to 0.24 among Chinese Grouse populations and from 0.01 to 0.44 in Hazel *** from a population of Chinese Grouse residing in the Qilian mountains and from the European populations of Hazel Grouse(including samples from sweden,Germany and Northeast Poland)were the most inbred(FROH ranged from 0.10 to 0.23 and 0.11 to 0.44,respectively).These levels are comparable to other highly inbred populations of *** Grouse from northern China and Chinese Grouse residing in the Qinghai-Tibetan Plateau showed relatively lower inbreeding *** of the ratio between deleterious missense mutations and synonymous mutations revealed higher levels in Chinese Grouse as compared to Hazel *** results are possibly explained by higher fixation rates,mutational melt down,in the range-restricted Chinese Grouse compared to the wide-ranging Hazel ***,when we compared the relatively more severe class of loss-of-function muta-tions,Hazel Grouse had slightly higher levels than Chinese Grouse,a result which may indicate that purifying selection(purging)has been more efficient in Chinese Grouse on this class of mutations.

关键词： Genetic load Inbreeding Purifying selection Qinghai-Tibetan Plateau ROH Tetrastes

san Antonio witnesses Chinese urological achievements:The World Chinese Urological society achievement and Rising star Awards at the 16th annual meeting

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UroPrecision 2024年第2期2卷 65-72页

作者： Guiting Lin Run Wang tom F.Lue Knuppe Molecular Urology Laboratory Department of UrologySchool of MedicineUniversity of CaliforniaSan FranciscoCaliforniaUSA Department of Urology Uniersity of Texas MD Anderson Cancer CenterHoustonTexasUSA Division of Urology Department of SurgeryUniversity of Texas McGovern Medical SchoolHoustonTexasUSA

san Antonio,May 3,2024—The 16th Annual meeting of the World Chinese Urological society(WCUs)was successfully held in san Antonio,drawing together experts and scholars from around the globe in the field of Chinese *** conference served as a platform for academic exchange,as well as an occasion for medical professionals of Chinese descent to learn from,inspire,and motivate one *** events are crucial for advancing research and clinical practice in Chinese urology worldwide,and the success of this conference signals a bright and progressive future for the field.

关键词： World exchange witness

16th Annual Meeting of the World Chinese Urological society:Reunion and sharing of global Chinese urological advances

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UroPrecision 2024年第2期2卷 62-64页

作者： Guiting Lin Run Wang tom F.Lue Knuppe Molecular Urology Laboratory Department of UrologySchool of MedicineUniversity of CaliforniaSan FranciscoCaliforniaUSA Department of Urology MD Anderson Cancer CenterHoustonTexasUSA Department of surgery Division of UrologyUniversity of Texas McGovern Medical SchoolHoustonTexasUSA

1|*** few years without in-person meeting during the American Urological Association(AUA)due to COVID-19 pandemic,the world's brightest Chinese urologists and urological researchers gathered *** May 3,2024,the 16th Annual Meeting of the World Chinese Urological society(WCUs)was successfully held in san Antonio,*** conference attracted Chinese experts and scholars from the field of urology around the world to discuss and share the latest academic achievements and research *** significant event provided an important academic exchange platform for Chinese urology experts globally.

关键词： union globally World

secondary rectal linitis plastica caused by prostatic adenocarcinoma-magnetic resonance imaging findings and dissemination pathways:A case report

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World Journal of Radiology 2024年第9期16卷 473-481页

作者： Andres Antonio Labra Giancarlo schiappacasse Rolando Alfonso Cocio Jorge tom.s Torres Fernando Omar González Joaquin Alberto Cristi Marcela schultz Department of Radiology Facultad de Medicina Clínica Alemana-Universidad del DesarrolloSantiago 7650568Región MetropolitanaChile Department of Pathology Clínica Alemana de SantiagoSantiago 7650568Región MetropolitanaChile

BACKGROUND secondary rectal linitis plastica(RLP)from prostatic adenocarcinoma is a rare and poorly understood form of metastatic spread,characterized by a desmoplastic response and concentric rectal wall infiltration with mucosal *** complicates endoscopic diagnosis and can mimic gastrointestinal *** case series underscores the critical role of magnetic resonance imaging(MRI)in identifying the distinct imaging features of RLP and highlights the importance of considering this condition in the differential diagnosis of patients with a history of prostate *** sUMMARY Three patients with secondary RLP due to prostatic adenocarcinoma presented with varied clinical *** first patient,a 76-year-old man with advanced prostate cancer,had rectal pain and *** showed diffuse prostatic invasion and significant rectal wall thickening with a characteristic"target sign"*** second,a 57-year-old asymptomatic man with elevated prostatespecific antigen levels and a history of prostate cancer exhibited rectoprostatic angle involvement and rectal wall thickening on MRI,with positron emission tomography/computed tomography PsMA confirming the prostatic origin of the metastatic *** third patient,an 80-year-old post-radical prostatectomy,presented with refractory *** revealed a neoplastic mass infiltrating the rectal *** all cases,MRI consistently showed stratified thickening,concentric signal changes,restricted diffusion,and contrast enhancement,which were essential for diagnosing secondary *** confirmed the prostatic origin of the neoplastic involvement in the *** Recognizing MRI findings of secondary RLP is essential for accurate diagnosis and management in prostate cancer patients.

关键词： Rectal linitis plastica Prostatic adenocarcinoma signet ring cell carcinoma Metastatic spread Magnetic resonance imaging Concentric wall infiltration Case report

Multi‐energy system horizon planning:Early decarbonisation in China avoids stranded assets

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Energy Internet 2024年第1期1卷 81-98页

作者： Xiaowei Zhou Kai strunz tom Brown Hongbin sun Fabian Neumann Department of sustainable Electric Networks and sources of Energy Technische Universität BerlinBerlinGermany Department of Digital Transformation in Energy systems Technische Universität BerlinBerlinGermany Department of Electrical Engineering Tsinghua UniversityBeijingChina

An appropriate decarbonisation pathway is crucial to achieving carbon neutrality in China before *** paper studies decarbonisation pathways for China's energy system between 2020 and 2060 using an open,provincial,and hourly resolved,networked model within the context of multi‐period planning with myopic investment *** representative decarbonisation pathways are compared,with particular attention to the synergies of coupling the electricity and heating *** early and steady path in which emissions are strongly reduced in the first decade is more cost‐effective than following a late and rapid *** decarbonisation in the electricity sector avoids stranded in-vestments in fossil infrastructure and preserves the carbon budget for later emissions in the difficult‐to‐decarbonise heating *** the existing coal power plants by adding carbon capture facilities is cost‐effective in both decarbonisation *** hourly and non‐interrupted resolution for a full weather year reveals the balancing strategies of highly renewable,sector‐coupled *** significant seasonal variation of heat demand dominates long‐term storage behaviours.

关键词： system horizon sector

Discrimination of polysorbate 20 by high-performance liquid chromatography-charged aerosol detection and characterization for components by expanding compound database and library

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Journal of Pharmaceutical Analysis 2024年第5期14卷 722-732页

作者： shi-Qi Wang Xun Zhao Li-Jun Zhang Yue-Mei Zhao Lei Chen Jin-Lin Zhang Bao-Cheng Wang sheng Tang tom Yuan Yaozuo Yuan Mei Zhang Hian Kee Lee Hai-Wei shi Jiangsu Institute for Food and Drug Control Nanjing210019China school of Pharmacy China Pharmaceutical UniversityNanjing211112China school of Pharmacy Nanjing University of Chinese MedicineNanjing210046China Chinese Pharmacopoeia Commission Beijing100061China Nanjing Well Pharmaceutical Group Co. Ltd.Nanjing210018China school of Environmental and Chemical Engineering Jiangsu University of Science and TechnologyZhenjiangJiangsu212003China University of Massachusetts Amherst Amherst01003USA Department of Chemistry National University of SingaporeSingapore117543Singapore

Analyzing polysorbate 20(Ps20)composition and the impact of each component on stability and safety is crucial due to formulation variations and individual *** similar structures and polarities of Ps20 components make accurate separation,identification,and quantification *** this work,a high-resolution quantitative method was developed using single-dimensional high-performance liquid chromatography(HPLC)with charged aerosol detection(CAD)to separate 18 key components with multiple *** separated components were characterized by ultra-high-performance liquid chromatography-quadrupole time-of-flight mass spectrometry(UHPLC-Q-TOF-Ms)with an identical gradient as the HPLC-CAD *** polysorbate compound database and library were expanded over 7-time compared to the commercial *** method investigated differences in Ps20 samples from various origins and grades for different dosage forms to evaluate the composition-process ***-Q-TOF-Ms identified 1329 to 1511 compounds in 4 batches of Ps20 from different *** method observed the impact of 4 degradation conditions on peak components,identifying stable components and their tendencies to ***-CAD and UHPLC-Q-TOF-Ms results provided insights into fingerprint differences,distinguishing quasi products.

关键词： Polysorbate 20 Component Database Discrimination Degradation

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长白山地区蜜环菌属真菌资源

菌物研究 2024年第2期22卷 149-157页

作者：朱艳杨非一吕孟洁袁雪艳 HsIANG tom 刘淑艳吉林农业大学植物保护学院长春130118 吉林农业大学菌物学院长春130118 食药用菌教育部工程研究中心长春130118 圭尔夫大学环境科学学院圭尔夫市3227

蜜环菌属Armillaria真菌是长白山地区代表性野生菌,具有重要的食药用价值。本研究采用样方调查和随机踏查相结合的方法对该地区蜜环菌属物种展开资源调查和种类鉴定,结果表明,长白山地区蜜环菌有5种,即北方蜜环菌Armillaira borealis、... 详细信息

蜜环菌属Armillaria真菌是长白山地区代表性野生菌,具有重要的食药用价值。本研究采用样方调查和随机踏查相结合的方法对该地区蜜环菌属物种展开资源调查和种类鉴定,结果表明,长白山地区蜜环菌有5种,即北方蜜环菌Armillaira borealis、法国蜜环菌***、黄小蜜环菌***、芥黄蜜环菌***以及Armillaira sp.,其中北方蜜环菌为吉林省新记录种,法国蜜环菌为该地区的优势物种。多样性分析结果表明,在阔叶林、针阔混交林、针叶林3种林型中,针阔混交林中蜜环菌属α多样性指数相对较高,说明针阔混交林的物种丰富度最高。本研究为蜜环菌属资源的开发和利用提供理论基础和实践依据。

关键词：蜜环菌属物种多样性长白山