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Journal of Natural Gas Chemistry 2011年第5期20卷 547-552页

作者： tingting zhao hongxia wang Key Laboratory of Design and Synthesis of Functional Materials and Green Catalysis Colleges of Heilongjiang Province Harbin Normal University Harbin 150025 Heilongjiang China

The effect of steam-treatment to HZSM-5 zeolite and Mo/HZSM-5 with a steaming time range of 0.5-1 h on the catalytic performance of methane dehydro-aromatization （MDA） over Mo/HZSM-5 catalyst prepared with impregnation has been studied in detail in combination with the characterization of 1H MAS NMR technique. Both the deactivation rate constant （kd） and the Brtnsted acid sites per unit cell were calculated to quantitatively evaluate the stability of Mo/HZSM-5 catalysts treated with steam at 813 K before and after impregnation of molybdenum species, and the corresponding variation of their Brtnsted acid sites. The results reveal that a V-shape relationship between kd and the number of B 1 acid sites per unit cell is presented on Mo/HZSM-5 catalyst under the tested steam-treatment and reaction conditions.

关键词： steam-treatment HZSM-5 zeolite Mo/HZSM-5 methane dehydro-aromatization in the absence of oxygen

Hydrogen sulfide reduces oxidative stress in Huntington's disease via Nrf2

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Neural Regeneration Research 2025年第6期20卷 1776-1788页

作者： Zige Jiang Dexiang Liu tingting Li Chengcheng Gai Danqing Xin Yijing zhao Yan Song Yahong Cheng Tong Li Zhen wang Department of Physiology School of Basic Medical SciencesCheeloo College of MedicineShandong UniversityJinanShandong ProvinceChina Department of Medical Psychology and Ethics School of Basic Medicine SciencesCheeloo College of MedicineShandong UniversityJinanShandong ProvinceChina Department of Neurosurgery Surgery Qingdao Municipal HospitalQingdaoShandong ProvinceChina

The pathophysiology of Huntington's disease involves high levels of the neurotoxin quinolinic acid. Quinolinic acid accumulation results in oxidative stress, which leads to neurotoxicity. However, the molecular and cellular mechanisms by which quinolinic acid contributes to Huntington's disease pathology remain unknown. In this study, we established in vitro and in vivo models of Huntington's disease by administering quinolinic acid to the PC12 neuronal cell line and the striatum of mice, respectively. We observed a decrease in the levels of hydrogen sulfide in both PC12 cells and mouse serum, which was accompanied by down-regulation of cystathionine β-synthase, an enzyme responsible for hydrogen sulfide production. However, treatment with NaHS(a hydrogen sulfide donor) increased hydrogen sulfide levels in the neurons and in mouse serum, as well as cystathionine β-synthase expression in the neurons and the mouse striatum, while also improving oxidative imbalance and mitochondrial dysfunction in PC12 cells and the mouse striatum. These beneficial effects correlated with upregulation of nuclear factor erythroid 2-related factor 2 expression. Finally, treatment with the nuclear factor erythroid 2-related factor 2inhibitor ML385 reversed the beneficial impact of exogenous hydrogen sulfide on quinolinic acid-induced oxidative stress. Taken together, our findings show that hydrogen sulfide reduces oxidative stress in Huntington's disease by activating nuclear factor erythroid 2-related factor 2,suggesting that hydrogen sulfide is a novel neuroprotective drug candidate for treating patients with Huntington's disease.

关键词： apoptosis cystathionine-β-synthase nuclear factor erythroid 2-related factor 2 Huntington's disease hydrogen sulfide mitochondrion neuroplasticity oxidative stress quinolinic acid reactive oxygen species

基于乳脂肪球膜结构以提高液态乳体系的稳定性:乳脂肪球膜构建机制综述

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食品科学 2025年第2期46卷 308-316页

作者：王鑫于景华赵亭亭刘晓辉天津科技大学食品科学与工程学院食品营养与安全国家重点实验室天津300457 河北省功能油脂微胶囊化技术创新中心河北石家庄052160

乳脂肪球起源于乳腺上皮细胞,脂肪球膜中的脂质和蛋白质通过静电斥力和空间位阻维持脂肪球的稳定性,同时膜上的成分具有特定的营养特性。脂肪球界面的重新构建对液态乳制品的品质至关重要,本文对近年来加工中乳脂肪球界面构建机制的研... 详细信息

乳脂肪球起源于乳腺上皮细胞,脂肪球膜中的脂质和蛋白质通过静电斥力和空间位阻维持脂肪球的稳定性,同时膜上的成分具有特定的营养特性。脂肪球界面的重新构建对液态乳制品的品质至关重要,本文对近年来加工中乳脂肪球界面构建机制的研究进行总结并发掘共通之处。均质会破坏脂肪球膜的原生结构,导致膜结构重新排列。此外,热处理也会改变蛋白质的结构,并引起脂质结构域的侧向分离。同时,脂肪球膜上蛋白质和脂质的热响应会导致原始膜成分的损失。外源添加物通过改善油水界面和增强脂肪球的稳定性,参与体系稳定化的重构建。未来需深入研究脂肪球膜构建机制与宏观体系的联系,并优化特定的加工条件,以获得更高品质的乳制品。

关键词：脂肪球脂肪球膜脂肪球膜蛋白脂质域重构建

B-Spline Method for Spatio-Temporal Inverse Model

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Journal of Systems Science & Complexity 2022年第6期35卷 2336-2360页

作者： wang hongxia zhao Zihan WU Yuehua LUO Xuehong School of Statistics and Data Science Nanjing Audit UniversityNanjing 211815China Department of Mathematics and Statistics York UniversityTorontoOntarioCanada Department of Statistics and Data Science School of EconomicsXiamen UniversityXiamen 361005China

Inverse models can be used to estimate surface fluxes in terms of the observed atmospheric concentration measurement *** paper proposes a new nonparametric spatio-temporal inverse model and provides the global expressions for the estimates by employing the B-spline *** authors establish the asymptotic normality of the estimators under mild *** authors also conduct numerical studies to evaluate the finite sample performance of the proposed ***,the authors apply the method to anthropogenic carbon dioxide(CO_(2))emission data from different provinces of Canada to illustrate the validity of the proposed techniques.

关键词： Inverse model spatio-temporal heterogeneity spatio-temporal correlation

Ideas, properties, and standards of fracture repositioning with osteopathy in traditional Mongolian medicine in China

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Journal of Traditional Chinese Medicine 2015年第1期35卷 117-120页

作者： wang Mei wang hongxia zhao Namula Department of Orthopedics and Traumatology lnner Mongolia International Hospital of Mongolian Hospital Medicine Beijing Dascom Software Technology Development Co. Ltd. Department of Orthopedics and Traumatology lnner Mongolia International Hospital of Mongolian Hospital Medicine Orthopedics Research Base of Inner Mongolia University for the Nationalities

OBJECTIVE: To explore the unique ideas, properties, and standards of fracture repositioning with osteopathy in traditional Mongolian medicine in ***: Based on the natural life concept of "integration of universe and man," osteopathy in traditional Mongolian medicine in China uses the modern principles and methods of physiology, psychol-ogy, and biomechanics. Against this background,we explored the unique ideas, properties, and standards of fracture repositioning in traditional Mongolian ***: Fracture treatment with osteopathy in traditional Mongolian medicine in China is based on(a) the ideas of natural, sealed, self and dynamic repositioning of fractures;(b) the properties of structural continuity and functional completeness;(c) the standards of "integration of movement and stillness" and "force to force." CONCLUSION: The unique ideas, properties, and standards of fracture repositioning with osteopathy in traditional Mongolian medicine in China have resulted in the widespread use of such techniques and represents the future direction of the development of fracture repositioning.

关键词： Osteopathy Medicine, Mongolian traditional Fracture repositioning

Cooperation between single atom catalyst and support to promote nitrogen electroreduction to ammonia:A theoretical insight

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Journal of Energy Chemistry 2024年第9期96卷 336-344页

作者： Wanying Guo Siyao wang hongxia wang Qinghai Cai Jingxiang zhao College of Chemistry and Chemical Engineering Harbin Normal UniversityHarbin 150025HeilongjiangChina

The co-catalysis between single atom catalyst(SAC)and its support has recently emerged as a promising strategy to synergistically boost the catalytic activity of some complex electrochemical reactions,encompassing multiple intermediates and ***,we utilized defective BC_(3)monolayer-supported SACs as a prototype to investigate the cooperative effects of SACs and their support on the catalytic performance of the nitrogen reduction reaction(NRR)for ammonia(NH_(3))*** results showed that these SACs can be firmly stabilized on these defective BC_(3)supports with high stability against ***,co-activation of the inert N_(2)reactant was observed in certain embedded SACs and their neighboring B atoms on certain BC3 sheets due to the noticeable charge transfer and significant N–N bond *** high-throughput screening revealed that the Mo/DV_(CC)and W/DV_(CC)exhibit superior NRR catalytic performance,characterized by a low limiting potential of−0.33 and−0.43 V,respectively,which can be further increased under acid conditions based on the constant potential ***,varying NRR catalytic activities can be attributed to the differences in the valence state of active ***,further microkinetic modeling analysis displayed that the turnover frequency of N_(2)–to–NH_(3)conversion on Mo/DV_(CC)is as large as 1.20×10^(−3)s^(−1)site^(−1) at 700 K and 100 bar,thus guaranteeing its ultra-fast reaction *** results not only suggest promising advanced electrocatalysts for NRR but also offer an effective avenue to regulate the electrocatalytic performance via the co-catalytic metal–support interactions.

关键词： Co-catalysis Single atom catalyst Nitrogen reduction DFT computations

Distribution characteristics of indoor oxygen concentration under natural ventilation in oxygen-enriched buildings at high altitudes

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Building Simulation 2021年第6期14卷 1823-1841页

作者： Cong Song tingting zhao Yanfeng Liu Dengjia wang State Key Laboratory of Green Building in Western China Xi'an University of Architecture and TechnologyXi'anShaanxi 710055China School of Building Services Science and Engineering Xi'an University of Architecture and TechnologyXi'anShaanxi 710055China

Diffuse oxygen supply is an important means to improve the indoor oxygen environment of buildings and ensure physiological and psychological health of immigrants in plateau *** research on oxygen enrichment strategies at high altitudes has mainly focused on confined spaces under mechanical ventilation,with few studies on the distribution of indoor oxygen concentration under natural ventilation in actual *** study used a verified computational fluid dynamics(CFD)method to investigate the indoor oxygen distribution with practical consideration of natural ventilation at high *** results showed that the oxygen distribution under wind-driven natural ventilation was more nonuniform than that under buoyancy-driven natural ventilation,with the ratio of local oxygen concentration to overall-mean oxygen concentration,the k value,between 0.8 and 1.3 under wind-driven natural ventilation and between 0.9 and 1.1 under buoyancy-driven natural *** effects of meteorological condition and oxygen source position on indoor spatial oxygen distribution characteristics were explored with careful examination in human occupied zone under lying,sitting and standing *** results can provide implications for effective and energy saving design of indoor oxygen supply system in plateau buildings.

关键词： high altitude indoor environment-oxygen concentration distribution natural ventilation oxygen enrichment

Investigation on the Performance of the Pump-Free Double Heat Source Ejector Refrigeration System with R1234yf

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Journal of Thermal Science 2022年第5期31卷 1452-1464页

作者： YU Meihong zhao hongxia wang Xinli HAN Jitian LAI Yanhua School of Energy and Power Engineering Shandong UniversityJi’nan250061China School of Control Science and Engineering Shandong UniversityJi’nan250061China

A pump is needed in an ejector refrigeration system,which makes the system high cost and complicated and hinders its application.A pump-free double heat source ejector refrigeration system using R1234yf as working fluid is proposed in which an injector driven by another heat source replaces the liquid circulating pump,making the system more affordable,simpler and more *** effect of different operation conditions on entrainment ratios and the influence of different factors on system performance are analyzed on the basis of mass,momentum and energy conservation *** influence degree of each factor on system performance is investigated by the orthogonal test *** condenser temperature has the largest effect on system *** pressure drop in the suction chamber of gas-liquid injector has the least impact on system *** COP can reach about 0.35 under a certain working *** system can be driven by two different temperature heat sources with no electricity needed,and it is a good choice for places with abundant heat resources or lack of electricity.

关键词： ejector refrigeration system injector entrainment ratio coefficient of performance(COP)

Amending Research on the Expression of the Contact Force of the Spindle Barrel Finishing Based on EDEM Simulation

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Chinese Journal of Mechanical Engineering 2020年第6期33卷 105-117页

作者： Na wang Shengqiang Yang tingting zhao Bo Cao Chengwei wang College of Mechanical and Vehicle Engineering Taiyuan University of TechnologyTaiyuan030024China Shanxi Key Laboratory of Precision Machining Taiyuan University of TechnologyTaiyuan030024China

The spindle barrel finishing is commonly used to improve the surface integrity of the important parts of the high-end equipment while it is difficult to provide enough test artifacts for the traditional trial and error experiment to obtain the desirable processing *** EDEM simulation of the spindle barrel finishing can provide effective help for the process design,however,the difference between the simulation and experiment is closely related to the selection of the contact model during *** this paper,simulations and experiments are conducted based on the identical apparatus and conditions to facilitate the comparison and validation between each *** on the Hertz contact theory,the effect of the material properties of contact objects and the relative position of the workpiece on the contact force is *** expression of the correlation coefficient of the contact model is *** the formula for calculating the contact force between the barrel finishing abrasive and the workpiece that includes influence coefficient of the material properties and the relative positions is ***,the contact force calculation formula is verified by changing the rotating *** result shows that the material correction coefficient ranges from 1.41 to 2.38,which is inversely related to the equivalent modulus *** position correction coefficient ranges from 2.0 to *** relative error value between the calculation result and the experimental test result is from 0.58%to 14.07%.This research lay a theoretical foundation for the correction theory of the core elements of the spindle barrel finishing process.

关键词： Spindle barrel finishing processing EDEM simulation Hertz-Mindlin(no slip)contact model Average contact force Modified coefficient

Advances in friction of aluminium alloy deep drawing

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Friction 2024年第3期12卷 396-427页

作者： Yiren GAO hongxia LI Danyang zhao Minjie wang Xiaobo FAN School of Mechanical Engineering Dalian University of TechnologyDalian 116023China

Broad use of lightweight aluminium alloy parts in automobile manufacturing,aerospace,electronic communication,and rail transit is mainly formed through deep drawing *** drawing friction is a key boundary condition for controlling the forming quality of aluminium alloy ***,due to the oxidation and adhesion tendency of aluminium alloys,the tribological situations of aluminium alloy deep drawing(AADD)system is more complicated than those of traditional deep drawing of steel ***,the study of AADD friction is essential for manufacturing high-performance aluminium alloy ***,aiming to provide a valuable reference for researchers in related fields,a comprehensive review of AADD friction is provided,including friction mechanism,influencing factors,friction measurement,friction model,friction simulation,and lubrication-free friction ***,a brief conclusion and several current challenges were discussed.

关键词： aluminium alloy deep drawing(AADD) influencing factors friction measurement friction model friction control