检索结果-南通市图书馆

Research 2024年第1期2023卷 721-733页

作者： Miao Liu Haiqing Zhang Zhichao Wang tingting mo Xuefeng Lai Yaling He Minghui Jiang Meian He Weijia Kong Tangchun Wu Xiaomin Zhang Department of Occupational and Environmental Health Ministry of Education Key Laboratory of Environment and Healthand State Key Laboratory of Environmental Health(Incubating)School of Public HealthTongji Medical CollegeHuazhong University of Science and TechnologyWuhanHubeiChina Department of Otorhinolaryngology Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhanHubeiChina Department of Epidemiology and Biostatistics School of Public HealthTongji Medical CollegeHuazhong University of Science and TechnologyWuhanHubeiChina

Evidence available on the independent and combined associations of sleep duration,bedtime,and genetic predisposition with hearing loss was *** present study included 15,827 participants from the Dongfeng–Tongji cohort *** risk was characterized by polygenic risk score(PRS)based on 37 genetic loci related to hearing *** conducted multivariate logistic regression models to assess the odds ratio(OR)for hearing loss with sleep duration and bedtime,as well as the joint association and interaction with *** showed that hearing loss was independently associated with sleeping≥9 h/night compared to the recommended 7 to9:00 *** 10:00 *** to those with bedtime>10:00 *** 11:00 p.m.,with estimated ORs of 1.25,1.27,and 1.16,respectively.

关键词： Middle hearing fen

Determination of Benzoylaconitine Compounds in the Decoctions of Aconiti Lateralis Radix Praeparata(Heishun Pieces),Trichosanthis Fructus and Their Combination

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Medicinal Plant 2024年第3期15卷 1-3,22页

作者： Luyao XIE Xiaoxia LI Jing FU Jinhua LIU Yaobin HUANG Xuri WEI tingting mo Shaomian PAN Lin HUANG Jiabao MA Graduate School of Guangxi University of Chinese Medicine Nanning 530200China The First Affiliated Hospital of Guangxi University of Chinese Medicine Nanning 530023China

[Objectives]This study was conducted to determine the contents of benzoylmesaconine,benzoylaconitine and benzoylhypacoitine in the decoctions of Heishun pieces,Trichosanthis Fructus and their combination.[Methods]Heishun pieces,Trichosanthis Fructus and their combination were extracted for different time periods,and then *** was performed using an Agilent ZORBAX SB-C 18 chromatographic column(4.6 mm×250 mm,5μm)and acetonitrile-0.02 mol/L sodium dihydrogen phosphate as the mobile phase at a flow rate of 1 mL/min and a column temperature of 30℃,and the sample volume was 20μ*** detection wavelength was 230 nm.[Results]The total amounts of benzoylmesaconine,benzoylaconitine and benzoylhypacoitine in the single decoction group of Heishun pieces were all significantly different from those in the combined decoction group at corresponding time.[Conclusions]The total content of the benzoylaconitine type increased significantly after the combined decoction of Heishun pieces and Fructus Trichosanthis,which proves the scientificity of"eighteen incompatible medicaments,19 counteraction"in traditional Chinese medicine to some extent.

关键词： Aconiti Lateralis Radix Praeparata Trichosanthis Fructus Benzoylaconitine compound Content determination

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

法国判例的法源地位、作用与制约

法国研究 2024年第1期 96-112页

作者：莫婷婷广西财经学院中南大学法学院法国蒙彼利埃大学法学院

判例是彰显公平正义的载体。依托制定法传统,精准划分制定法与判例的边界,明确判例的法学性质及制度价值是成文法国家判例制度发挥其应有价值的前提。在与我国同样有着浓厚制定法传统的法国,司法机构行使最终法律解释权而作出的、起到... 详细信息

判例是彰显公平正义的载体。依托制定法传统,精准划分制定法与判例的边界,明确判例的法学性质及制度价值是成文法国家判例制度发挥其应有价值的前提。在与我国同样有着浓厚制定法传统的法国,司法机构行使最终法律解释权而作出的、起到生成法律规则作用的判决具有独立法源地位。法源地位的确立强化了法国判例的事实约束力,使其能在尊重司法权与立法权分离原则的基础上,持续发挥解释制定法、推动制定法发展的作用。同时,也为“准宪法”条款等制定法及合宪性审查对判例进行约束提供了正当性依据。法国法学界论述判例法源地位的路径、判例制度的构建及相关约束措施的设置,为我国指导性案例制度的发展提供了可供参考的样本。

关键词：法国判例制度独立法源地位判例的作用对判例的约束

补肾调肝降浊方对肥胖多囊卵巢综合征大鼠白色脂肪褐变的影响

同方期刊数据库博看期刊评论

在线全文

学校读者我要写书评

暂无评论

中华中医药杂志 2024年第7期39卷 3729-3734页

作者：庞颖刘雁峰吴豆豆孔鑫靓莫婷婷陈然北京核工业医院北京100045 北京中医药大学东直门医院北京100700 北京中医药大学北京100029

目的:探讨补肾调肝降浊方治疗肥胖型多囊卵巢综合征(PCOS)的可能作用机制。方法:将60只6周龄SPF级SD雌性大鼠分为空白组(10只)和造模组(50只),造模组采用来曲唑灌胃联合高脂饮食喂养制备肥胖型PCOS大鼠模型,将造模成功的50只大鼠随机分... 详细信息

目的:探讨补肾调肝降浊方治疗肥胖型多囊卵巢综合征(PCOS)的可能作用机制。方法:将60只6周龄SPF级SD雌性大鼠分为空白组(10只)和造模组(50只),造模组采用来曲唑灌胃联合高脂饮食喂养制备肥胖型PCOS大鼠模型,将造模成功的50只大鼠随机分为模型组,中药低、中、高剂量组和二甲双胍组。给药结束后,ELISA法检测血清中瘦素(LP)、脂联素(ADPN);WesternBlot及RT-qPCR法检测大鼠白色脂肪组织(WAT)和棕色脂肪组织(BAT)中腺苷酸活化蛋白激酶(AMPK)、过氧化物酶增殖激活受体-共激活子-1α(PGC-1α)、解偶联蛋白1(UCP-1)蛋白及mRNA表达情况。结果:与空白组比较,模型组大鼠LP显著升高和ADPN显著降低(P<0.01);与模型组比较,中药低、中、高剂量组LP显著降低(P<0.01),中药中、高剂量组ADPN显著升高(P<0.05)。与模型组比较,中药中剂量组可以激活WAT中AMPK/PGC-1α通路及提高UCP-1的表达(P<0.01);二甲双胍组亦可激活WAT中AMPK/PGC-1α通路(P<0.05,P<0.01)。与空白组比较,模型组BAT中AMPK、PGC-1α、UCP-1mRNA和蛋白表达降低(P<0.05,P<0.01);与模型组比较,中药中剂量组AMPK、PGC-1α、UCP-1mRNA和蛋白表达显著升高(P<0.01,P<0.05)。结论:补肾调肝降浊方可以通过激活肥胖型PCOS模型大鼠AMPK/PGC-1α通路,提高UCP-1表达,降低LP,提高ADPN水平,促使WAT褐变,激活BAT,使机体的脂代谢恢复正常,降低游离睾酮,恢复排卵。

关键词：补肾调肝降浊方多囊卵巢综合征肥胖白色脂肪组织褐变棕色脂肪组织机制

胶艾汤联合米非司酮治疗安装曼月乐后不规则出血的临床观察

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

佛山科学技术学院学报（自然科学版） 2024年第4期42卷 75-80页

作者：莫婷婷黄洁琳陈慕音江门市妇幼保健院妇科广东江门529000

目的探讨胶艾汤联合米非司酮治疗安装左炔诺孕酮宫内节育系统后不规则出血的疗效。方法选取2022年4月至2024年3月我院收治的60例因异常子宫出血-排卵障碍(AUB-O)安装左炔诺孕酮宫内节育系统后出现不规则阴道流血的患者,随机分为对照组... 详细信息

目的探讨胶艾汤联合米非司酮治疗安装左炔诺孕酮宫内节育系统后不规则出血的疗效。方法选取2022年4月至2024年3月我院收治的60例因异常子宫出血-排卵障碍(AUB-O)安装左炔诺孕酮宫内节育系统后出现不规则阴道流血的患者,随机分为对照组和联合治疗组,各30例。在安装左炔诺孕酮宫内节育系统后给予米非司酮治疗过程中,实验组与对照组的两组患者在干预前后的血红蛋白浓度、不良反应、依从性、出血时间、出血量进行比较。结果联合治疗组患者在治疗后的总有效率显著高于对照组,且经过统计学分析证明两组之间存在显著差异。此外,联合治疗组在干预后的一些指标,如血红蛋白浓度、子宫内膜厚度、出血时间、出血量以及某些激素水平,与对照组相比均呈现出显著差异,并且这些差异也具有统计学意义。同时,联合治疗组的总依从性也显著高于对照组,差异具有统计学意义。结论胶艾汤联合米非司酮治疗安装左炔诺孕酮宫内节育系统后不规则出血患者,能够改善血红蛋白浓度,缩短出血时间,降低出血量,提高患者依从性。

关键词：胶艾汤米非司酮左炔诺孕酮宫内节育系统不规则出血临床观察

神经外科重症患者院内检查标准化转运方案的构建与实施

在线全文

学校读者我要写书评

暂无评论

护理实践与研究 2024年第6期21卷 792-799页

作者：王玉果苏微微王鲁繁周亭亭侯辉辉墨婷婷滨州医学院附属医院山东省滨州市256600

目的以校正改良早期预警评分(MEWS)和转运核查单为基础建立神经外科重症患者院内检查标准化分级转运模式,并观察临床应用效果。方法选取2022年1—6月某三级甲等综合医院神经外科重症监护室行院内检查转运的656例患者为研究对象,其中,2... 详细信息

目的以校正改良早期预警评分(MEWS)和转运核查单为基础建立神经外科重症患者院内检查标准化分级转运模式,并观察临床应用效果。方法选取2022年1—6月某三级甲等综合医院神经外科重症监护室行院内检查转运的656例患者为研究对象,其中,2022年1—3月的321例患者为对照组,实行常规转运;2022年4—6月的335例患者为观察组,实施标准化分级转运模式,转运前使用校正MEWS对患者进行病情分级、使用转运核查单做好患者转运前准备工作,根据病情分级配备转运人员及设备。比较两组患者转运时长及转运相关不良事件发生率。结果标准化分级转运模式下,观察组患者CT、CTA、MRI 3项检查各自所用的转运时间及总转运时间短于对照组,组间比较差异有统计学意义(P<0.05)。观察组患者转运不良事件发生率低于对照组,组间比较差异有统计学意义(P<0.05)。结论基于校正MEWS和转运核查单的标准化分级转运模式可提高转运效率,降低转运风险,保障患者转运安全。

关键词：神经外科重症监护室改良早期预警评分分级转运转运核查单患者安全

补肾解郁调冲方治疗肾虚肝郁型多囊卵巢综合征不孕的临床研究

同方期刊数据库博看期刊评论

在线全文

学校读者我要写书评

暂无评论

山东中医杂志 2024年第7期43卷 700-706页

作者：莫婷婷刘雁峰陈然潘雪徐子涵郭霖霖北京中医药大学东直门医院北京100700 天津市西青区中医院天津300380 北京中医药大学第三附属医院北京100029

目的:观察补肾解郁调冲方联合来曲唑治疗肾虚肝郁型多囊卵巢综合征(PCOS)不孕患者的临床疗效。方法:选取83例肾虚肝郁型PCOS不孕患者按随机数字表法分为对照组41例和观察组42例。对照组采用来曲唑促排卵治疗,观察组加用补肾解郁调冲方... 详细信息

目的:观察补肾解郁调冲方联合来曲唑治疗肾虚肝郁型多囊卵巢综合征(PCOS)不孕患者的临床疗效。方法:选取83例肾虚肝郁型PCOS不孕患者按随机数字表法分为对照组41例和观察组42例。对照组采用来曲唑促排卵治疗,观察组加用补肾解郁调冲方进行治疗。观察两组治疗前后排卵率、妊娠率、中医证候评分、月经周期评分、性激素、超声学指标、多毛及痤疮积分、焦虑自评量表评分、抑郁自评量表评分,以及血清吻肽(Kiss1)、多巴胺(DA)、5-羟色胺(5-HT)和去甲肾上腺素(NE)水平。结果:与对照组相比,观察组患者的排卵率和妊娠率显著提高,患者痤疮、焦虑、抑郁和中医证候显著改善。与治疗前相比,治疗后观察组患者卵泡个数和卵巢体积显著减小,血清黄体生成素、黄体生成素与卵泡刺激素的比值、睾酮、泌乳素水平显著降低,Kiss1水平显著降低,DA、5-HT水平显著升高,差异均具有统计学意义(P<0.05)。观察组总有效率为88.10%,临床疗效显著优于对照组(P<0.05)。结论:补肾解郁调冲方能有效改善肾虚肝郁型PCOS不孕患者的临床症状,改善性激素紊乱状态,促进排卵,提高临床妊娠率,改善焦虑抑郁症状,这可能与其调节血清吻肽和单胺类神经递质水平有关。

关键词：多囊卵巢综合征不孕症补肾解郁调冲方肾虚肝郁心理应激

Development in oxide metallurgy for improving the weldability of high -strength low-alloy steel-Combined deoxidizers and microalloying elements

同方期刊数据库博看期刊评论

在线全文

学校读者我要写书评

暂无评论

International Journal of Minerals,Metallurgy and Materials 2024年第6期31卷 1263-1284页

作者： tingting Li Jian Yang State Key Laboratory of Advanced Special Steel School of Materials Science and EngineeringShanghai UniversityShanghai 200444China

The mechanisms of oxide metallurgy include inducing the formation of intragranular acicular ferrite(IAF)using micron-sized inclusions and restricting the growth of prior austenite grains(PAGs)by nanosized particles during *** chaotically oriented IAF and refined PAGs inhibit crack initiation and propagation in the steel,resulting in high impact *** work summarizes the com-bined effect of deoxidizers and alloying elements,with the aim to provide a new perspective for the research and practice related to im-proving the impact toughness of the heat affected zone(HAZ)during the high heat input *** complex deoxidation with other strong deoxidants,such as Mg,Ca,Zr,and rare earth metals(REMs),can improve the toughness of the heat-affected zone(HAZ)by re-fining PAGs or increasing IAF ***,it is difficult to identify the specific phase responsible for IAF nucleation because ef-fective inclusions formed by complex deoxidation are usually *** alloying elements,such as C,Si,Al,Nb,or Cr,con-tents can impair HAZ toughness.A high C content typically increases the number of coarse carbides and decreases the potency of IAF ***,Cr,or Al addition leads to the formation of undesirable *** reduces the high-temperature stability of the ***,V,and B can enhance HAZ ***-containing precipitates present good thermal *** or V(C,N)is ef-fective in promoting IAF nucleation due to its good coherent crystallographic relationship with *** formation of the B-depleted zone around the inclusion promotes IAF *** interactions between alloying elements are complex,and the effect of adding dif-ferent alloying elements remains to be *** the future,the interactions between various alloying elements and their effects on ox-ide metallurgy,as well as the calculation of the nucleation effects of effective inclusions using first principles calculations will become the focus of

关键词： oxide metallurgy technology heat affected zone high-strength low-alloy steel intragranular acicular ferrite microalloying element

欧洲人权法院视野中的疫苗接种义务——以“瓦里夫等人诉捷克案”为例

在线全文

学校读者我要写书评

暂无评论

人权 2022年第6期 80-97页

作者：陈云良莫婷婷中南大学医疗卫生法研究中心中南大学法学院广西财经学院

“瓦里夫等人诉捷克案”涉及捷克立法以暂缓入学及罚款为惩罚机制,强制儿童接种常规疫苗,是否违反《欧洲人权公约》的问题。在案件的裁决中,欧洲人权法院重申,公共卫生措施的选择属于成员国自由裁量的范围。与此同时,为了将对个人利益... 详细信息

“瓦里夫等人诉捷克案”涉及捷克立法以暂缓入学及罚款为惩罚机制,强制儿童接种常规疫苗,是否违反《欧洲人权公约》的问题。在案件的裁决中,欧洲人权法院重申,公共卫生措施的选择属于成员国自由裁量的范围。与此同时,为了将对个人利益的侵犯限制在必要且合理的范围之内,欧洲人权法院明确常规疫苗强制接种的人权保障标准:具有法律依据、合法目的且符合“民主社会之所需”。据此,欧洲人权法院认为该案涉诉法律规定并不违反《欧洲人权公约》。作为该法院首次针对疫苗强制接种问题作出的回应,“瓦里夫等人诉捷克案”在维护成员国自由裁量权的基础上,强化了欧盟法在公共卫生领域的影响。此外,虽然“瓦里夫等人诉捷克案”仅涉及常规疫苗接种的问题,但在新冠肺炎全球大流行的背景下,该案提炼的人权保障标准,对新冠疫苗接种措施的出台也有一定的参考意义。

关键词：疫苗接种义务强制欧洲人权法院

Key elements that determine the efficacy of cupping therapy:A bibliometric analysis and review of clinical studies

在线全文

学校读者我要写书评

暂无评论

Journal of Traditional Chinese Medical Sciences 2020年第4期7卷 345-354页

作者： Jiayin Tao Pei Zhao tingting mo Ruiming Zhao Nan Yang Myeong Soo Lee Jianping Liu Huijuan Cao Dongzhimen Hospital Beijing University of Chinese MedicineBeijing100700China Department of Respiration China-Japan Friendship HospitalBeijing100029China Clinical Research Division Korea Institute of Oriental MedicineDaejeon34054South Korea Korean Convergence Medicine University of Science&TechnologyDaejeon34113South Korea Centre for Evidence-Based Chinese Medicine Beijing University of Chinese MedicineBeijing100029China

Objective:The aim of this review was to identify the possible mechanisms behind cupping therapy by employing an evidence-based approach,and to explore its possible regional and systemic effects in the human ***:We searched six electronic databases and four online trial registries for articles published up to January 1,*** studies on the mechanisms of retained cupping,flashing cupping,moving cupping,and vacuum cupping were considered for this *** methodological qualities of controlled studies were assessed using the National Institute for Clinical Excellence methodology checklist,the Newcastle-Ottawa Scale,and the Cochrane risk of bias *** statistical description and qualitative summary of results were used for data ***:Thirty-eight studies(37 full texts and one abstract)were included in this *** to the clinical heterogeneity among the studies,we could not conduct a *** results showed that the key factors that contribute to the efficacy of cupping therapy are negative pressure and *** therapy mainly causes local and systemic changes in hemodynamics,immune regulation,metabolism,and pain ***:We identified negative pressure as the key element behind cupping *** therapy may cause redistribution of oxygen at the cupping site and in neighboring tissues,thereby inducing a therapeutic effect by increasing regional blood *** may also induce metabolic change,immunomodulation,and ***,additional rigorous clinical research needs to be conducted to further clarify the mechanism behind cupping therapy.

关键词： Cupping therapy Negative pressure Immunomodulation Temperature Hemodynamics Bibliometrics