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Numerical solutions of 2-D steady compressible natural convection using high-order flux reconstruction

Acta Mechanica Sinica 2019年第2期35卷 401-410页

作者： Yaojie Yu Feng Liu Tingbo Zhou Chao Gao Ya Liu National Key Laboratory of Aerodynamic Design and Research Northwestern Polytechnical UniversityXi’an 710072 China Department of Mechanical and Aerospace Engineering University of California Irvine Irvine CA 92697 USA Facility Design and Instrumentation Institute China Aerodynamics Research and Development CenterMianyang 621000 China

Low Mach number flows are common and typical in industrial applications. When simulating these flows, performance of traditional compressible flow solvers can deteriorate in terms of both efficiency and accuracy. In this paper, a new high-order numerical method for two-dimensional(2-D)state low Mach number flows is proposed by combining flux reconstruction(FR)and preconditioning. Firstly, a Couette flow problem is used to assess the efficiency and accuracy of preconditioned FR. It is found that the FR scheme with preconditioning is much more efficient than the original FR scheme. Meanwhile,this improvement still preserves the numerical accuracy. Using this new method and without the Boussinesq assumption,classic natural convection is directly simulated for cases of small and large temperature differences. For the small temperature difference, a p and h refinement study is conducted to verify the grid convergence and accuracy. Then, the influence of the Rayleigh number (Ra) is analyzed. By comparing with the reference results, the numerical results of preconditioned FR is very close to that calculated by incompressible solvers. Furthermore, a large temperature difference test case is calculated and analyzed, indicating this method is not limited by the Boussinesq assumption and is also applicable to heat convection with large temperature differences.

关键词： Flux reconstruction Preconditioning method Low Mach flows Natural convection

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Protective Effects of Six PPTs on Hypoxia/Reoxygenation Induced Cardiomyocyte Injury by Different Treatments

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Medicinal Plant 2022年第5期13卷 66-69,73页

作者： tingbo CHEN Dong HUANG Ziming zhou Gengting DONG Zhongshan Torch Polytechnic Zhongshan 528436China Zhongshan Functional Cosmetics(Zhongshan Torch Polytechnic)Engineering Research Center Zhongshan 528436China Zhongshan Hospital of Traditional Chinese Medicine Zhongshan 528400China

[Objectives]To detect the protective effects of six protopanaxatriols(PPTs)on hypoxia/reoxygenation(H/R)induced cardiomyocyte injury by different treatments.[Methods]The 3-[4,5-dimethylthiazol-2-yl]-2,5 diphenyl tetrazolium bromide(MTT)assay was used for detecting the protective effects of six PPTs including ginsenoside Rg1,Re,Rf,Rg2,(R)Rh1 and(S)Rh1 on cell viability reduced by H/R in different treatments.And the adenosine triphosphate(ATP)content and mitochondrial membrane potential(MMP)were used for detecting the mitochondrial function change during PPTs treatment.[Results]Among six PPTs,ginsenoside Rg1,Re,Rf,Rg2 and(R)Rh1 at the concentration of 12.5μM significantly increased the cell survival when treated before and during H/R.These five PPTs also significantly increased the ATP content and MMP reduced by H/R in the same manner.In comparison,only Rg1 significantly increased the cell viability compared with H/R group by pretreating and treating the cells during hypoxia process.[Conclusions]Different treatments affect the protective effects of PPTs.When treated before and during H/R,ginsenoside Rg1,Re,Rf,Rg2 and(R)Rh1 protect the cardiomyocyte against H/R injury mitochondrial function,and only ginsenoside Rg1 has protective effects when treated before and during hypoxia process.

关键词： Protopanaxatriols(PPTs) Ginsenoside Rg1 Mitochondrial function Treatment process

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Abscisic acid and jasmonic acid are involved in drought priming-induced tolerance to drought in wheat

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The Crop Journal 2021年第1期9卷 120-132页

作者： Xiao Wang Qing Li Jingjing Xie Mei Huang Jian Cai Qin zhou tingbo Dai Dong Jiang National Technique Innovation Center for Regional Wheat Production/Key Laboratory of Crop Ecophysiology Ministry of AgricultureNanjing Agricultural UniversityNanjing 210095JiangsuChina

Drought stress is a limiting factor for wheat production and food security.Drought priming has been shown to increase drought tolerance in wheat.However,the underlying mechanisms are unknown.In the present study,the genes encoding the biosynthesis and metabolism of abscisic acid(ABA)and jasmonic acid(JA),as well as genes involved in the ABA and JA signaling pathways were up-regulated by drought priming.Endogenous concentrations of JA and ABA increased following drought priming.The interplay between JA and ABA in plant responses to drought priming was further investigated using inhibitors of ABA and JA biosynthesis.Application of fluridone(FLU)or nordihydroguaiaretic acid(NDGA)to primed plants resulted in lower chlorophyll-fluorescence parameters and activities of superoxide dismutase and glutathione reductase,and higher cell membrane damage,compared to primed plants(PD)under drought stress.NDGA+ABA,but not FLU+JA,restored priming-induced tolerance,as indicated by a finding of no significant difference from PD under drought stress.Under drought priming,NDGA induced the suppression of ABA accumulation,while FLU did not affect JA accumulation.These results were consistent with the expression of genes involved in the biosynthesis of ABA and JA.They suggest that ABA and JA are required for priming-induced drought tolerance in wheat,with JA acting upstream of ABA.

关键词： Wheat Drought priming Abscisic acid Jasmonic acid Antioxidant activity

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The different root apex zones contribute to drought priming induced tolerance to a reoccurring drought stress in wheat

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The Crop Journal 2021年第5期9卷 1088-1097页

作者： Xiao Wang Jing Chen Jiakun Ge Mei Huang Jian Cai Qin zhou tingbo Dai Luis Alejandro Jose Mur Dong Jiang National Technique Innovation Center for Regional Wheat Production/Key Laboratory of Crop Ecophysiology Ministry of Agriculture/Nanjing Agricultural UniversityNanjing 210095JiangsuChina Institute of Biological Environmental and Rural SciencesAberystwyth UniversityAberystwyth SY233DAUK

Drought priming is a promising approach to improve tolerance to further drought in wheat.The root apex plays important roles in drought however,its contribution to drought priming remains unknown.To provide mechanistic insights into this process,the transcriptomes and proteomes at three different zones along the root axis under drought stress were analyzed.Physiological assessment of root growth indicated that priming augmented roots growth in response to drought and also the levels of protective proline and glycine betaine.Scanning across the proximal to the distal zones of the root apex indicated increases the transcription of genes involved in primary and secondary metabolism.Conversely,genes related to translation,transcription,folding,sorting and degradation,replication and repair were increased in the apex compared to the proximal zone.A single drought episode suppressed their expression but prior drought priming served to maintain expression with recurrent drought stress.The differentially primed responses genes were mainly involved in the pathways related to plant hormone signaling,stress defense and cell wall modification.The prediction of regulatory hubs using Cytoscape implicated signaling components such as the ABA receptor PYL4 as influencing antioxidant status and the cell cycle.Based our integrative transcriptomic-proteomic assessments we present a model for drought priming protected plant hormone signaling transduction pathways to drive the cell cycle and cell wall loosening to confer beneficial effects on roots to counter the effects of drought.This model provides a theoretical basis for improvement of drought tolerance in wheat,via an increased understanding of drought priming induced drought tolerance.

关键词： Wheat Drought priming Drought tolerance Root Transcriptome

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Over expression of TaFer gene from Tamarix androssowii improves iron and drought tolerance in transgenic Populus tomentosa

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Journal of Forestry Research 2019年第1期30卷 171-181页

作者： Bo Zhao Jingli Yang Wenjing Yao Boru zhou Wei Zheng tingbo Jiang State Key Laboratory of Tree Genetics and Breeding Northeast Forestry University Department of Pharmacy Heilongjiang University of Chinese Medicine Research Center on Life Sciences and Environmental Sciences Harbin University of Commerce

Ferritin, a universal intracellular protein, can store large amounts of iron and improve plant resistance to abiotic and biotic stress. In this study, a ferritin gene(TaFer) from Tamarix androssowii Litv. was transferred into Populus tomentosa Carr. cv 'BJR01' via Agrobacterium. Six independent transgenic lines were obtained with a tolerance to kanamycin and three were randomly selected for further analysis. The PCR and RT-PCR results indicate that the TaFer gene had been integrated into the poplar genome. The effect of the gene on abiotic stress tolerance was tested, and the results show that transgenic plants improve growth, had higher chlorophyll and lower MDA contents, and higher relative electrical conductivity,fewer changes of SOD and POD activities, higher iron content, higher root ferric reductase activity and lower levels of ROS accumulation and cell death in response to drought, Fe-insufficient or Fe-excess tolerance. These results indicate that the TaFer gene can improve abiotic stress tolerance in transgenic Populus tomentosa.

关键词： Tarmarix andnssowii Ferritin Iron Genetic transformation Stress resistance

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Correction To:POD Nanozyme optimized by charge separation engineering for light/pH activated bacteria catalytic/photodynamic therapy

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Signal Transduction and Targeted Therapy 2023年第6期8卷 3185-3187页

作者： Changyu Cao tingbo Zhang Nan Yang Xianghong Niu Zhaobo zhou Jinlan Wang Dongliang Yang Peng Chen Liping Zhong Xiaochen Dong Yongxiang Zhao Key Laboratory of Flexible Electronics (KLOFE) and Institute of Advanced Materials (IAM) School of Physical and Mathematical Sciences Nanjing Tech University (NanjingTech) Nanjing 211816 China School of Physics Southeast University Nanjing 211189 China School of Chemical and Biomedical Engineering Nanyang Technological University 62 Nanyang Drive Singapore 637459 Singapore National Center for International Biotargeting Theranostics Guangxi Key Laboratory of Biotargeting Theranostics Collaborative Innovation Center for Targeting Tumor Theranostics Guangxi Medical University Nanning Guangxi 530021 China

Correction to:Signal Transduction and Targeted Therapy https://***/10.1038/s41392-022-00900-8,published online 28 March 2022 The plate photo from Control in Figure 4c of the published work was mistakenly used when editing the photos,and the corrected version is demonstrated below.The results and conclusions of this paper were not affected by this error.

关键词： Figure separation charge

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大气环境变化对真空管道温度场影响的研究

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实验流体力学 2023年第1期37卷 72-81页

作者：高超严日华武斌周廷波西北工业大学翼型、叶栅空气动力学国家级重点实验室西安710072 中国空气动力研究与发展中心设备设计与测试技术研究所绵阳621000

真空管道内的温度分布直接影响管道内磁浮列车的气动性能及运行安全,研究大气环境对真空管道温度场的影响,对未来真空管道列车运输系统的建设具有重要意义。基于四川省成都市近5年(2017—2021)的气象数据,总结了各季节的太阳辐射强度、... 详细信息

真空管道内的温度分布直接影响管道内磁浮列车的气动性能及运行安全,研究大气环境对真空管道温度场的影响,对未来真空管道列车运输系统的建设具有重要意义。基于四川省成都市近5年(2017—2021)的气象数据,总结了各季节的太阳辐射强度、空气湿度、大气温度和风速等大气环境参数,建立了真空管道辐射传热数值计算方法,采用DO(Discrete Ordinate)辐射模型研究了太阳辐射对真空管道内气流温度的影响,得到了不同季节、不同真空度下管道内气流温度分布及变化规律。研究表明:在太阳辐射的影响下,真空管道内气流温度提升较大;在相同真空度下,管道内气流温度夏季最高、冬季最低;随着真空度逐渐降低,管道内气流温度逐渐升高,真空度为0.1 atm(约10.1 kPa)时,夏季管道内气流温度最大提升56.60 K。

关键词：真空管道辐射传热自然对流大气环境计算流体力学

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POD Nanozyme optimized by charge separation engineering for light/pH activated bacteria catalytic/photodynamic therapy

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Signal Transduction and Targeted Therapy 2022年第4期7卷 1334-1342页

作者： Changyu Cao tingbo Zhang Nan Yang Xianghong Niu Zhaobo zhou Jinlan Wang Dongliang Yang Peng Chen Liping Zhong Xiaochen Dong Yongxiang Zhao Key Laboratory of Flexible Electronics(KLOFE)and Institute of Advanced Materials(IAM) School of Physical and Mathematical SciencesNanjing Tech University(NanjingTech)Nanjing 211816China School of Physics Southeast UniversityNanjing 211189China School of Chemical and Biomedical Engineering Nanyang Technological University62 Nanyang DriveSingapore 637459Singapore National Center for International Biotargeting Theranostics Guangxi Key Laboratory of Biotargeting TheranosticsCollaborative Innovation Center for Targeting Tumor TheranosticsGuangxi Medical UniversityNanningGuangxi 530021China

The current feasibility of nanocatalysts in clinical anti-infection therapy,especially for drug-resistant bacteria infection is extremely restrained because of the insufficient reactive oxygen generation.Herein,a novel Ag/Bi2MoO6(Ag/BMO)nanozyme optimized by charge separation engineering with photoactivated sustainable peroxidase-mimicking activities and NIR-II photodynamic performance was synthesized by solvothermal reaction and photoreduction.The Ag/BMO nanozyme held satisfactory bactericidal performance against methicillin-resistant Staphylococcus aureus(MRSA)(~99.9%).The excellent antibacterial performance of Ag/BMO NPs was ascribed to the corporation of peroxidase-like activity,NIR-II photodynamic behavior,and acidity-enhanced release of Ag^(+).As revealed by theoretical calculations,the introduction of Ag to BMO made it easier to separate photo-triggered electronhole pairs for ROS production.And the conduction and valence band potentials of Ag/BMO NPs were favorable for the reduction of O_(2) to·O_(2)^(−).Under 1064 nm laser irradiation,the electron transfer to BMO was beneficial to the reversible change of Mo^(5+)/Mo^(6+),further improving the peroxidase-like catalytic activity and NIR-II photodynamic performance based on the Russell mechanism.In vivo,the Ag/BMO NPs exhibited promising therapeutic effects towards MRSA-infected wounds.This study enriches the nanozyme research and proves that nanozymes can be rationally optimized by charge separation engineering strategy.

关键词： mechanism. separation charge

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Simultaneous Determination of 20 Ginsenosides in Panax Ginseng and the Change of These Compounds with Cultivation Time in Different Cultivars

Simultaneous Determination of 20 Ginsenosides in Panax Ginse...

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第十四届全国中药和天然药物学术研讨会

作者： HUANG Baoming CHEN tingbo LIU Liang zhou Hua Macau University of Science and Technology

Panax ginseng is an important herbal medicine that has more than one thousand years of history in medical use.The ginsengs of different cultivation time,geographical origins and cultivars will have different composition of secondary metabolites.As the most important secondary metabolites,the content of the ginsenosides will make the difference in the quality of ginsengs.We invent a new approach to estimate the quality of ginsengs that 20 ginsenosides are simultaneous quantified in ginsengs using UHPLC-TOF/MS.The method validation showed good precision,LLOQ and LLOD,matrix effect,linear and recovery.After the determination,the content of the 20 ginsenosides in 350 ginseng samples are analysis by using the orthogonal projection to latent structure-discriminant analysis（OPLS-DA）.The results show that the OPLS-DA model can separate the samples of different ages,which are two to six years old.And this model can also separate the samples of some particular cultivars including the cultivated ginsengs and the wild ginsengs.

关键词： UHPLC-TOF/MS ginsenoside OPLS-DA

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多孔介质对风洞管道内压缩波传播的影响

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实验流体力学 2023年第3期37卷 50-58页

作者：周廷波于馨凝周国龙贾乐凡张家忠中国空气动力研究与发展中心设备设计与测试技术研究所绵阳621000 成都流体动力创新中心成都610072 西安交通大学能源与动力工程学院西安710048

磁浮飞行风洞运行中产生的压缩波在风洞管道内传播至风洞端面后反射,可能在测试段与模型发生碰撞,干扰试验结果。为了消除压缩波对风洞试验的影响,采用在风洞管道内部铺设多孔介质的方式降低风洞内压缩波强度,依据现有的多孔介质压降模... 详细信息

磁浮飞行风洞运行中产生的压缩波在风洞管道内传播至风洞端面后反射,可能在测试段与模型发生碰撞,干扰试验结果。为了消除压缩波对风洞试验的影响,采用在风洞管道内部铺设多孔介质的方式降低风洞内压缩波强度,依据现有的多孔介质压降模型推导管道内压缩波通过多孔介质区域压降规律方程,并根据方程内影响多孔介质消波能力的参数进行了数值模拟。结果表明:多孔介质对不同强度压缩波均有相似比例的压降作用,其消波能力随压缩波强度、多孔介质惯性阻力系数及厚度的增大而增大;但当多孔介质惯性阻力系数及厚度增大时,部分压缩波不能通过多孔介质而是被其反射,反射压缩波强度也随惯性阻力系数及厚度的增大而增大。增加层数可以在不改变多孔介质其他参数的情况下降低反射压缩波强度,提高多孔介质的总体消波能力;多孔介质可以在较宽的环境压力(0.0001~1 atm)内保持良好的消波能力。

关键词：压缩波多孔介质磁浮飞行风洞

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