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Stability of unicortical locked fixation versus bicortical non-locked fixation for forearm fractures

Bone Research 2014年第2期2卷 131-135页

作者： timothy j pater Steve I Grindel Gregory j Schmeling Mei Wang Department of Orthopaedic Surgery Medical College of Wisconsin Milwaukee WI USA Orthopaedic & Rehabilitation Engineering Center Marquette University Milwaukee WI USA

Locking plate fixation is being widely applied for fixation of forearm fractures and has many potential advantages, such as fixed angle fixation and improved construct stability, especially in osteoporotic bone. Biomechanical data comparing locking devices to commonly used Low Contact Dynamic Compression （LCDCP） plates for the fixation of forearm fractures has been lacking. The purpose of this study was to compare the fixation stability of a 3.5-mm unicortical locked plate with bicortical non-locked LCDCP plates. Six matched pairs of fresh frozen cadaveric forearms were randomly assigned to unicortical locked and bicortical unlocked groups. Non-destructive four-point bending and torsional test was performed on the ulna and radius separately, using a servohydraulic testing system to obtain construct stiffness of the intact specimens and specimens after osteotomy and plating. The specimens were then loaded to failure to test the fixation strength. The locked unicortical fixation showed significantly higher bending stiffness than the unlocked bicortical fixation, but with significantly lower stiffness and strength in torsion. Fixation strength was comparable between the two groups under bending, but significantly greater in the bicortical non-locked group under torsion. Findings from this study suggest that postoperative rehabilitation protocols may need modification to limit torsional loading in the early stage when using locked unicortical fixation. The study also points out the potential advantage of a hybrid fixation that combines locked unicortical and unlocked bicortical screws.

关键词： Stability of unicortical locked fixation versus bicortical non-locked fixation for forearm fractures

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Cross-Wedge Rolling of Shafts With an Eccentric Step

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journal of Iron and Steel Research International 2011年第6期18卷 26-30页

作者： Zbigniew pater Lublin University of Technology Lublin 20-618Poland

A new concept for forming eccentric shafts on the basis of the cross-wedge rolling （CWR） process was presented. This concept was based on the application of special guides, which, by acting on a billet, lead to its controlled movement in the vertical direction. This movement made possible eccentric cutting of tools into the billet. FEM calculations and experimental rolling tests clearly confirmed the effectiveness of the proposed forming method.

关键词： cross-wedge rolling process eccentric shaft FEM

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Multi-Wedge Cross Rolling of Balls

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journal of Iron and Steel Research International 2013年第10期20卷 46-50页

作者： Zbigniew pater Mechanical Faculty Lublin University of Technology

The multi-wedge cross rolling process of forming balls is described. The process tool for rolling 8 balls with a diameter of 35 mm is presented. The course of the rolling process, distributions of forming forces as well as maps of effective strain and temperature in the obtained balls are presented by finite element modeling （FEM）. Ex- perimental tests of simultaneous forming of 4 balls with a diameter of 22 mm conducted in laboratory conditions at Lublin University of Technology have proved that the balls obtained in multi-wedge cross rolling are of good quality and can therefore be used in both ball mills and rolling bearings.

关键词： cross wedge rolling ball finite element modeling (FEM) experimental test

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Cavity formation in cross-wedge rolling processes

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journal of Iron and Steel Research International 2019年第1期26卷 1-10页

作者： Zbigniew pater janusz Tomczak Tomasz Bulzak Department of Computer Modelling and Metal Forming Technologies Mechanical Engineering FacultyLublin University of TechnologyLublin 20-618Poland

The problem of end-face cavity formation in parts produced by cross-wedge rolling was studied in order to reduce material *** cavity depth was measured by the displacemern ***-one different cases of rolling were analysed by finile element method to determine the effects of process parameters such as the wedge tool angle,the temperature of material,the tool velocity and the reduction ratio on the depth of end-face *** between these parameters are examined in order to establish depe ndencies enabling quick and simple selection of a con cavity allowance in order to remove the *** equations for calculating the con cavity allowance were verified in an experimental process for manufacturing ball pins with the use of flat *** tests were performed using a billet with its length selected in compliance with the established *** experimental results demonstrate that the proposed solution is a viable method for end-face cavity removal.

关键词： Cross-wedge rolling End-face cavity Concavity allowance Ball pin

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CD40 stimulation as a molecular adjuvant for cancer vaccines and other immunotherapies

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Cellular & Molecular Immunology 2022年第1期19卷 14-22页

作者： timothy N.j.Bullock Department of Pathology University of VirginiaCharlottesvilleVAUSA

The substantial advances attained by checkpoint blockade immunotherapies have driven an expansion in the approaches used to promote T cell access to the tumor microenvironment to provide targets for checkpoint *** in any T cell response to a tumor antigen is the capacity of dendritic cells to initiate and support such ***,the rationale and early immunobiology of CD40 as a master regulator of dendritic cell activation is reviewed,with further contextualization and appreciation for the role of CD40 stimulation not only in cancer vaccines but also in other contemporary immune-oncology approaches.

关键词： CD40 vaccine CD40L T cell dendritic cell

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Kinetics of glyphosate and aminomethylphosphonic acid sorption onto montmorillonite clays in soil and their translocation to genetically modified corn

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journal of Environmental Sciences 2024年第1期135卷 669-680页

作者： Meichen Wang Kelly j Rivenbark timothy D Phillips Veterinary Physiology and Pharmacology College of Veterinary Medicine and Biomedical SciencesTexas A&M UniversityTX 77845USA

The co-occurrence of glyphosate(GLP)and aminomethylphosphonic acid(AMPA)in contaminated water,soil,sediment and plants is a cause for concern due to potential threats to the ecosystem and human health.A major route of exposure is through contact with contaminated soil and consumption of crops containing GLP and AMPA ***,clay-based sorption strategies for mixtures of GLP and AMPA in soil,plants and garden produce have been very *** this study,in vitro soil and in vivo genetically modified corn models were used to establish the proof of concept that the inclusion of clay sorbents in contaminated soils will reduce the bioavailability of GLP and AMPA in soils and their adverse effects on plant *** of chemical concentration(1–10 mg/kg),sorbent dose(0.5%-3%in soil and 0.5%-1%in plants)and duration(up to 28 days)on sorption kinetics were *** time course results showed a continuous GLP degradation to *** inclusion of calcium montmorillonite(CM)and acid processed montmorillonite(APM)clays at all doses significantly and consistently reduced the bioavailability of both chemicals from soils to plant roots and leaves in a dose-and time-dependent manner without detectable *** treated with 0.5%and 1%APM inclusion showed the highest growth rate(p≤0.05)and lowest chemical bioavailability with up to 76%reduction in roots and57%reduction in *** indicated that montmorillonite clays could be added as soil supplements to reduce hazardous mixtures of GLP and AMPA in soils and plants.

关键词： Glyphosate AMPA Adsorption Soil remediation Plant Hydroponic system

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Making the link between ADF and 4D STEM:Resolution,transfer and coherence

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Chinese Physics B 2024年第11期33卷 26-33页

作者： Peter D.Nellist timothy j.Pennycook Department of Materials University of OxfordOxfordUK EMAT University of AntwerpGroenenborgerlaan 1712020 AntwerpBelgium

Steve Pennycook is a pioneer in the application of high-resolution scanning transmission electron microscopy(STEM)and in particular the use of annular dark-field(ADF)*** we show how a general framework for 4D STEM allows clear links to be made between ADF imaging and the emerging methods for reconstructing images from 4D STEM data *** show that both ADF imaging and ptychographical reconstruction can be thought of in terms of integrating over the overlap regions of diffracted discs in the detector *** approach allows the similarities in parts of their transfer functions to be understood,though we note that the transfer functions for ptychographic imaging cannot be used as a measure of information *** also show that conditions of partial spatial and temporal coherence affect ADF imaging and ptychography similarly,showing that achromatic interference can always contribute to the image in both cases,leading to a robustness to partial temporal coherence that has enabled high-resolution imaging.

关键词： image forming and processing phase retrieval electron microscopy scanning transmission electron microscope(STEM)

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Adapting the botanical landscape of Melbourne Gardens(Royal Botanic Gardens Victoria)in response to climate change

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Plant Diversity 2017年第6期39卷 338-347页

作者： timothy j.Entwisle Chris Cole Peter Symes Royal Botanic Gardens Victoria

Botanic gardens around the world maintain collections of living plants for science, conservation, education, beauty and more. These collections change over time-in scope and content-but the predicted impacts of climate change will require a more strategic approach to the succession of plant species and their landscapes. Royal Botanic Gardens Victoria has recently published a 'Landscape Succession Strategy'for its Melbourne Gardens, a spectacular botanical landscape established in 1846. The strategy recognizes that with 1.6 million visitors each year, responsibility for a heritage-listed landscape and the need to care for a collection of 8500 plant species of conservation and scientific importance, planting and planning must take into account anticipated changes to rainfall and temperature. The trees we plant today must be suitable for the climate of the twenty-second century. Specifically, the Strategy sets out the steps needed over the next twenty years to transition the botanic garden to one resilient to the climate modelled for2090. The document includes a range of practical measures and achievable(and at times somewhat aspirational) targets. Climate analogues will be used to identify places in Australia and elsewhere with conditions today similar to those predicted for Melbourne in 2090, to help select new species for the collection. Modelling of the natural and cultivated distribution of species will be used to help select suitable growth forms to replace existing species of high value or interest. Improved understanding of temperature gradients within the botanic garden, water holding capacity of soils and plant water use behaviour is already resulting in better targeted planting and irrigation. The goal is to retain a similar diversity of species but transition the collection so that by 2036 at least 75% of the species are suitable for the climate in 2090. Over the next few years we hope to provide 100% of irrigation water from sustainable water sources, and

关键词： Climate change Landscape succession Botanic garden Uving collection

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Organization of future training in bariatric gastroenterology

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World journal of Gastroenterology 2017年第35期23卷 6371-6378页

作者： timothy R Koch timothy R Shope Christopher j Gostout Center for Advanced Laparoscopic General and Bariatric Surgery Med Star Washington Hospital Center and Georgetown University School of Medicine Division of Gastroenterology and Hepatology Mayo Clinic

A world-wide rise in the prevalence of obesity continues. This rise increases the occurrence of, risks of, and costs of treating obesity-related medical conditions. Diet and activity programs are largely inadequate for the long-term treatment of medically-complicated obesity. Physicians who deliver gastrointestinal care after completing traditional training programs, including gastroenterologists and general surgeons, are not uniformly trained in or familiar with available bariatric care. It is certain that gastrointestinal physicians will incorporate new endoscopic methods into their practice for the treatment of individuals with medically-complicated obesity, although the longterm impact of these endoscopic techniques remains under investigation. It is presently unclear whether gastrointestinal physicians will be able to provide or coordinate important allied services in bariatric surgery, endocrinology, nutrition, psychological evaluation and support, and social work. Obtaining longitudinal results examining the effectiveness of this ad hoc approach will likely be difficult, based on prior experience with other endoscopic measures, such as the adenoma detection rates from screening colonoscopy. As a longterm approach, development of a specific curriculum incorporating one year of subspecialty training in bariatrics to the present training of gastrointestinal fellows needs to be reconsidered. This approach should be facilitated by gastrointestinal trainees' prior residency training in subspecialties that provide care for individuals with medical complications of obesity, including endocrinology, cardiology, nephrology, and neurology. Such training could incorporate additional rotations with collaborating providers in bariatric surgery, nutrition, and psychiatry. Since such training would be provided in accredited programs, longitudinal studies could be developed to examine the potential impact on accepted measures of care, such as complication rates, outcomes, and

关键词： Obesity Bariatrics Bariatric surgery Intragastric balloon Endoscopic sleeve gastroplasty Nutrition Endoscopy Training

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Recent advances and trends in roll bonding process and bonding model:A review

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Chinese journal of Aeronautics 2023年第4期36卷 36-74页

作者： Zixuan LI Shahed REZAEI Tao WANG jianchao HAN Xuedao SHU Zbigniew pater Qingxue HUANG College of Mechanical and Vehicle Engineering Taiyuan University of TechnologyTaiyuan 030002China Institute of Materials Science Technische Universita¨t DarmstadtDarmstadt 64287Germany Faculty of Mechanical Engineering&Mechanics Ningbo UniversityNingbo 315211China Faculty of Mechanical Engineering Lublin University of TechnologyLublin20618Poland

This review presents a thorough survey of the roll bonding process with a focus on the bimetallic bars/tubes as well as the bonding models and *** review aims to provide insight into cold,hot and cryogenic bonding mechanisms at the micro and atomic scale and act as a guide for researchers working on roll bonding,other joining processes and bonding ***-while,the shortcomings of roll bonding processes are presented from the aspect of formable shapes,while bonding models are shown from the aspect of calculation time,convergence,interface behav-ior of dissimilar materials as well as hot bonding status *** well-accepted numerical methodologies of bonding models,namely the contact algorithm and cohesive zone model(CZM)of bonding models and in simulations of the bonding process are ***,recent advances and trends in the application of the combination of mechanical interlocking and metallurgical bonding,special energy fields,gradient structure,novel materials,green technology and soft computing method in the roll bonding process are also *** challenges for advancing and prospects of the roll bonding process and bonding model are presented in an attempt to shed some light on the future research direction.

关键词： Bimetallic Bonding mechanism Bonding model Numerical simulation Roll bonding process

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