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Detection of decline in estimated glomerular filtration rate in patients with type 2 diabetes by cystatin C-based equations

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World Journal of Nephrology 2024年第4期13卷 103-116页

作者： Tam Thai Thanh Tran tien kim ha Nhut Minh Phan Minh Van Le Tin Hoang Nguyen Department of Physiology Faculty of MedicineCan Tho University of Medicine and PharmacyCan Tho 900000Viet Nam Department of Functional Exploration Can Tho University of Medicine and Pharmacy HospitalCan Tho 900000Viet Nam School of Medicine and Pharmacy The University of Da NangDa Nang 550000Viet Nam Faculty of Medicine Can Tho University of Medicine and PharmacyCan Tho 900000Viet Nam

BACKGROUND Aging population is a significant issue in Viet Nam and across the *** individuals are at higher risk of chronic kidney disease(CKD),especially those with *** studies found that the estimated glomerular filtration rate(eGFR)determined using creatinine-based equations was not as accurate as that determined using cystatin C-based *** C-based equations may be beneficial in elderly patients with an age-associated decline in kidney *** determination of eGFR decline and associated factors would aid in appropriate interventions to improve kidney function in elderly patients with *** To determine the utility of cystatin C-based equations in early detection of eGFR decline and to explore factors associated with eGFR decline in elderly patients with *** This cross-sectional study included 93 participants aged≥60 years evaluated in Can Tho University of Medicine and Pharmacy Hospital between October 2022 and July 2023,including 47 and 46 participants with and without diabetes respectively,according to the American Diabetes Association criteria for *** kappa coefficient,Student’s t,Mann-Whitney,χ2,Pearson’s correlation,multivariate logistic regression,and multiple linear regression analyses were *** The eGFRs were lower with the cystatin C-based equations than with the creatinine-based *** agreement was found between the Modification of Diet in Renal Disease(MDRD)and CKD Epidemiology Collaboration(CKD-EPI)2021 creatinine-cystatin C equations(kappa=0.66).In the diabetes group,30%of the participants had low *** plasma glucose and glycated hemoglobin were associated with an increased risk of eGFR decline(P<0.05)and negatively correlated with eGFR(P=0.001).By multivariate logistic regression,total cholesterol,and exercise were independently associated with low *** multiple linear regression,higher plasma glucose levels were correlated with lower eGFR(P=0.026,

关键词： Cystatin C Estimated glomerular filtration rate Elderly Diabetes Nephrology Kidney function

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On Types of Isolated KKT Points in Polynomial Optimization

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Journal of Systems Science & Complexity 2023年第5期36卷 2186-2213页

作者： GUO Feng JIAO Liguo kim Do Sang PhaM tien-Son School of Mathematical Sciences Dalian University of TechnologyDalian 116024China Academy for Advanced Interdisciplinary Studies Northeast Normal UniversityChangchun 130024China Department of Applied Mathematics Pukyong National UniversityBusan 48513South Korea Department of Mathematics Dalat UniversityDalat 96300Vietnam.

Let f be a real polynomial function with n variables and S be a basic closed semialgebraic set in R^(n).In this paper,the authors are interested in the problem of identifying the type(local minimizer,maximizer or not extremum point)of a given isolated KKT point x^(*)of f over *** this end,the authors investigate some properties of the tangency variety of f on S at x^(*),by which the authors introduce the definition of faithful radius of f over S at x^(*).Then,the authors show that the type of x^(*)can be determined by the global extrema of f over the intersection of S and the Euclidean ball centered at x^(*)with a faithful ***,the authors propose an algorithm involving algebraic computations to compute a faithful radius of x*and determine its type.

关键词： Faithful radii KKT points polynomial functions tangency varieties types

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Endoscopic submucosal dissection for early gastric cancer:It is time to consider the quality of its outcomes

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World Journal of Gastroenterology 2023年第43期29卷 5800-5803页

作者： Gwang ha kim Internal Medicine Pusan National University School of Medicine and Biomedical Research InstitutePusan National University HospitalBusan 47241South Korea

Endoscopic resection,particularly endoscopic submucosal dissection(ESD),is widely used as a standard treatment modality for early gastric cancer(EGC)when the risk of lymph node metastasis is *** with surgical gastrectomy,ESD is a minimally invasive procedure with additional advantages,such as preservation of the entire stomach and maintenance of the patient’s quality of ***,not all patients achieve curative resection after ESD of *** patients require surgical gastrectomy after ESD to achieve a curative *** surgery after ESD,owing to non-curative resection,places considerable emotional and financial burdens on ***,as the number of endoscopists performing ESD has increased,the rate of non-curative resection after ESD has increased *** order to decrease the non-curative resection rate,as well as determine the ideal rate of non-curative resection after ESD,it is time to consider quality indicators for the outcomes of ESD for EGC.

关键词： Early gastric cancer Endoscopic resection Quality indicator

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Globus pharyngeus:A review of its etiology,diagnosis and treatment

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World Journal of Gastroenterology 2012年第20期18卷 2462-2471页

作者： Bong Eun Lee Gwang ha kim Department of Internal Medi cine Pusan National University School of Medicine and Biomedical Research InstitutePusan National University Hospital Busan 602-739South Korea

Globus is a persistent or intermittent non-painful sensation of a lump or foreign body in the *** is a commonly encountered clinical condition that is usually long-lasting,difficult to treat,and has a tendency to ***,due to the uncertain etiology of globus,it remains difficult to establish standard investigation and treatment strategies for affected patients. As a first step for managing globus,careful history taking and nasolaryngoscopy are *** the benign nature of the condition and the recent notion that gastroesophageal reflux disease is a major cause of globus,empirical therapy with a high dose of proton pump inhibitors is reasonable for patients with typical *** patients are nonresponsive to this therapy, definitive assessments such as endoscopy,multichannel intraluminal impedance/pH monitoring,and ma-nometry should be *** and language therapy,anti-depressants,and cognitive-behavioral therapy can be helpful in patients whose symptoms persist despite negative investigations.

关键词： Diagnosis Gastroesophageal reflux disease Globus Proton pump inhibitor Treatment

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A nanofilter composed of carbon nanotube-silver composites for virus removal and antibacterial activity improvement

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Journal of Environmental Sciences 2016年第4期28卷 275-283页

作者： Jun Pyo kim Jae ha kim Jieun kim Soo No Lee han-Oh Park Nano Development Team Bioneer Corporation Daejeon 306-220 Republic of Korea

We have developed a new nanofilter using a carbon nanotube-silver composite material that is capable of efficiently removing waterborne viruses and *** nanofilter was subjected to plasma surface treatment to enhance its flow rate,which was improved by approximately 62%.Nanoscale pores were obtained by fabricating a carbon nanotube network and using nanoparticle fixation technology for the removal of *** pore size of the nanofilter was approximately 38 nm and the measured flow rate ranged from 21.0 to 97.2 L/（min·m^2）under a pressure of 1–6 kgf/cm^2 when the amount of loaded carbon nanotube-silver composite was 1.0 mg/cm^*** nanofilter was tested against Polio-,Noro-,and Coxsackie viruses using a sensitive real-time polymerase chain reaction assay to detect the presence of viral particles within the *** trace of viruses was found to flow through the nanofilter with carbon nanotube-silver composite loaded above 0.8 mg/cm^***,the surface of the filter has antibacterial properties to prevent bacterial clogging due to the presence of 20-nm silver nanoparticles,which were synthesized on the carbon nanotube surface.

关键词： Carbon nanotube Silver nanoparticle Virus removal Nanofilter Water purification

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Surface properties of Al-doped ZnO thin film before and after CF_4/Ar plasma etching

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Plasma Science and Technology 2022年第7期24卷 194-200页

作者： Young-Hee JOO Gwan-ha kim Doo-Seung UM Chang-Il kim School of Electrical and Electronics Engineering Chung-Ang UniversitySeoul 06974Republic of Korea Department of Semiconductor Materials and Applications Korea PolytechnicSeongnam 13122Republic of Korea Department of Electrical Engineering Sejong UniversitySeoul 05006Republic of Korea

Al-doped ZnO(AZO) is considered as an alternative to transparent conductive oxide *** and achieving a stable surface are important challenges in the development and optimization of dry etching processes, which must be overcome for the application of AZO in various devices. Therefore, in this study, the etch rate and surface properties of an AZO thin film after plasma etching using the adaptive coupled plasma system were investigated. The fastest etch rate was achieved with a CF_(4)/Ar ratio of 50:50 sccm. Regardless of the ratio of CF_(4) to Ar,the transmittance of the film in the visible region exceeded 80%. X-ray photoelectron spectroscopy analysis of the AZO thin film confirmed that metal-F bonding persists on the surface after plasma etching. It was also shown that F eliminates O vacancies. Consequently, the work function and bandgap energy increased as the ratio of CF-4 increased. This study not only provides information on the effect of plasma on AZO thin film, but identifies the cause of changes in the device characteristics during device fabrication.

关键词： Al-doped ZnO plasma etching F-based plasma surface characteristics X-ray photoelectron spectroscopy ultraviolet photoelectron spectroscopy

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Analytical evaluation and experimental validation on dynamic rocking behavior for shallow foundation considering structural response

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Earthquake Engineering and Engineering Vibration 2022年第1期21卷 37-51页

作者： Kil-Wan Ko Jeong-Gon ha Dong-Soo kim Department of Civil and Environmental Engineering UC BerkeleyCalifornia 94720USA Advanced Structures and Seismic Safety Research Division Daejeon 34057Korea Department of Civil and Environmental Engineering KAISTDaejeon 34141Korea

The challenge in the practical application of rocking foundations is the estimation of its performance,particularly the rotation angle,during a strong *** this study,the dynamic rocking behavior for a shallow foundation considering structural response was evaluated through two analytical approaches:the conventional soil-foundation-structure interaction(SFSI)governing equation of a single-degree-of-freedom(SDOF)structure on a rocking shallow foundation,and the Housner rocking model(i.e.,a rocking rigid block on a rigid base).Both approaches were validated with dynamic centrifuge *** test models consisted of a soft soil deposit,a shallow rectangular foundation,and an SDOF structure dominated by a bending behavior.A total of 11 foundation-structure systems and six seismic waves,including recorded earthquake signals and sinusoidal waves,were *** results showed that the conventional SFSI equation well predicted the maximum rotation during strong ***,this method was less accurate regarding the rotational phase information and maximum rotation of the foundation during weak *** the other hand,although the modified Housner′s rocking model required five parameters relevant to a soil-foundation-structure system,it overestimated the maximum rotation of the foundation when compared with the results from dynamic centrifuge tests.

关键词： soil-foundation-structure interaction maximum rotation angle rocking foundation Housner rocking model dynamic centrifuge test

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Wearable Triboelectric Nanogenerators Based on Printed Polyvinylidene Fluoride Films Incorporated with Cobalt-Based Metal-Organic Framework for Self-Powered Mobile Electronics

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Energy & Environmental Materials 2024年第4期7卷 396-403页

作者： Myeong-Hyeon kim Sang-Joon Park Tae-Jun ha Department of Electronic Materials Engineering Kwangwoon UniversitySeoul 01897Korea

In this study,wearable triboelectric nanogenerators comprising bar-printed polyvinylidene fluoride(PVDF)films incorporated with cobalt-based metal-organic framework(Co-MOF)were *** enhanced output performance of the TENGs was attributed to the phase transition of PVDF from a-crystals toβ-crystals,as facilitated by the incorporation of the *** synthesis conditions,including metal ion,concentration,and particle size of the MOF,were optimized to increase open-circuit voltage(VOC)and open-circuit current(I_(SC))of PVDF-based *** addition to high operational stability,mechanical robustness,and long-term reliability,the developed TENG consisting of PVDF incorporated with Co-MOF(Co-MOF@PVDF)achieved a VOC of 194 V and an I_(SC)of 18.8μ***,the feasibility of self-powered mobile electronics was demonstrated by integrating the developed wearable TENG with rectifier and control units to power a global positioning system(GPS)*** local position of the user in real-time through GPS was displayed on a mobile interface,powered by the battery charged through friction-induced electricity generation.

关键词： bar printing phase transition polyvinylidene fluoride incorporated with cobalt-based metal-organic framework self-powered mobile electronics wearable triboelectric nanogenerators

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Role and Mechanisms of Actions of Thyroid Hormone on the Skeletal Development

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Bone Research 2013年第2期1卷 146-161页

作者： ha-Young kim Subburaman Mohan Musculoskeletal Disease Center Loma Linda VA HealthCare System Departments of Medicine Loma Linda University Division of Endocrinology Department of Internal MedicineWonkwang University Sanbon Hospital

The importance of the thyroid hormone axis in the regulation of skeletal growth and maintenance has been well established from clinical studies involving patients with mutations in proteins that regulate synthesis and/or actions of thyroid hormone. Data from genetic mouse models involving disruption and overexpression of components of the thyroid hormone axis also provide direct support for a key role for thyroid hormone in the regulation of bone metabolism. Thyroid hormone regulates proliferation and/or differentiated actions of multiple cell types in bone including chondrocytes, osteoblasts and osteoclasts. Thyroid hormone effects on the target cells are mediated via ligand-inducible nuclear receptors/transcription factors, thyroid hormone receptor （TR） a and ~, of which TRa seems to be critically important in regulating bone cell functions. In terms of mechanisms for thyroid hormone action, studies suggest that thyroid hormone regulates a number of key growth factor signaling pathways including insulin-like growth factor-I, parathyroid hormone related protein, fibroblast growth factor, Indian hedgehog and Wnt to influence skeletal growth. In this review we describe findings from various genetic mouse models and clinical mutations of thyroid hormone signaling related mutations in humans that pertain to the role and mechanism of action of thyroid hormone in the regulation of skeletal growth and maintenance.

关键词： thyroid hormone bone cartilage growth factors bone cells

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Optimal Spatial Allocation of Initial Attack Resources for Firefighting in the Republic of Korea Using a Scenario Optimization Model

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Journal of Mountain Science 2014年第2期11卷 323-335页

作者： Yohan LEE Byungdoo LEE Kyung ha kim Korea Rural Economic Institute 117-3 Hoegi-ro Dongdeamun-guSeoul 130-710 South Korea Korea Forest Research Institute Hoegiro 57 Dongdaemun-guSeoul 130-712 South Korea

【Title】 This study explores the optimal spatial allocation of initial attack resources for firefighting in the Republic of Korea. To improve the effectiveness of Korean initial attack resources with a range of policy goals, we create a scenario optimization model that minimizes the expected number of fires not receiving a predefined response. In this study, the predefined response indicates the number of firefighting resources that must arrive at a fire before the fire escapes and becomes a large fire. We use spatially explicit GIS-based information on the ecology, fire behavior, and economic characterizations important in Korea. The data include historical fire events in the Republic of Korea from 1991 to 2007, suppression costs, and spatial information on forest fire extent. Interviews with forest managers inform the range of we address in the decision model. Based on the geographic data, we conduct a sensitivity analysis by varying the parameters systematically. Information on the relative importance of the components of the settings helps us to identify “rules of thumb” for initial attack resource allocations in particular ecological and policy settings.

关键词： Spatial allocation Initial attack Firefighting The Republic of Korea Senario optimization

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