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Frequency of Floodplain Spills in the Tisza River Valley at Vylok (Transcarpathia, Ukraine)

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Journal of Geological Resource and Engineering 2021年第1期9卷 1-12页

作者： tibor izhak Department of Geography and Tourism Ferenc Rakoczi II Transcarpathian Hungarian College of Higher EducationBerehove 90202TranscarpathiaUkraine

Record-breaking floods occurred in the autumn of 1998 and the spring of 2001 in the lowlands of Transcarpathia,as well as in the areas of Hungary and Romania bordering Ukraine,which caused severe *** research was to determine the frequency of *** fluctuation of precipitation values brings about the increased frequency of the rivers’inundation as *** research is based on the data of the Tisza River’s inundation onto the flood plain near Vylok,as well as the precipitation data of the Rakhiv meteorological *** data series include the data of the latest 46 years(1970-2015),highlighting the pre-flood period of *** evaluate the data,we used linear trend analysis,which was edited using the Microsoft Excel spreadsheet *** results of the study showed that no particular changes in precipitation were observed,but the frequency of flood waves and the coverage of the floodplain with water showed a gradually increasing *** results of studying the amount of precipitation and the Tisza River’s inundation:in recent decades the frequency of flood wave formation and the coverage of the flood plain with water show a gradually increasing tendency.

关键词： Transcarpathia floods precipitation flood plain inundation

Managing type 2 diabetes:targeting a microbial enzyme as a novel treatment option

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Signal Transduction and Targeted Therapy 2024年第1期9卷 3-5页

作者： Anikó Keller-Pintér Tamás Korcsmáros tibor Vellai Department of Biochemistry Albert Szent-Györgyi Medical SchoolUniversity of SzegedSzeged6720Hungary Department of Metabolism Digestion and ReproductionImperial College LondonLondonW120NNUK Quadram Institute Bioscience Norwich Research ParkNorwichNR47UQUK Department of Genetics Eötvös Loránd University(ELTE)Budapest1117Hungary Hungarian Research Network HUN-REN-ELTE Genetics Research Group Budapest1117Hungary

In a recent Science article,Wang and colleagues showed that the dipeptidyl peptidase 4(DPP4)enzyme produced by the gut microbiota can interfere with the effect of host glucagon-like peptide-1(GLP-1)involved in stimulating insulin secretion,and the specific inhibitor of microbial DPP4(mDPP4),combined with clinical inhibitors of host DPP4 isoenzymes,further promotes blood glucose homeostasis.1 These results point out why certain patients respond inadequately to an antidiabetic medication.

关键词： homeostasis stimulating clinical

Constraints on what controls millennial-scale basin-wide denudation across mountain belts, Asia

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Science China Earth Sciences 2024年

作者： Ye YANG Steven A.BINNIE Sheng XU Cong-Qiang LIU tibor J.DUNAI Institute of Surface-Earth System Science School of Earth System Science Tianjin University Institute of Geology and Mineralogy University of Cologne

The terrestrial cosmogenic nuclide dataset consisting of 123310Be measurements of fluvial sediment samples across the Asian mountain belts is used to constrain the influence of climate,tectonics and topography on Earth-surface denudation processes.10Be-derived basin-wide denudation rates were recalculated using a Monte Carlo simulation approach that relied on pixel-by-pixel production *** rates derived span four orders of magnitude,from 7.4±0.7 mm kyr-1（1σ;Central Tibetan Plateau） to 9,646+777744mm kyr-1（1σ;Southern Tibetan Plateau）,with a median of 186 mm *** our results with the traditional basin-wide production rate scaling model using a centroid coordinate and mean elevation,suggests that 96.6%of production rates will be underestimated using the latter method,especially for basins with a large *** bias between both methods reaches as large as 40%,caused by basin hypsometry and the nonlinear scaling of production rate with elevation and *** of the correlations between uniformly recalculated denudation rates and tectonics,climate,topography,and rock lithology will facilitate the extrapolation of denudation rates in unknown basins using available *** the perspective of local scales,precipitation coupled with neotectonics-driven landslides is likely the most influential factor in subtropical Taiwan Island,while topography primarily constrains surface denudation rates in the eastern Tibetan Plateau within a narrow range of *** highland regions with glacier coverage,such as the Pamir,central and southern Tibetan Plateau,high denudation rates are affected by glaciation,whereas lower precipitation and high erosion base level may limit river incision and evolving relief in the Central Tibetan *** contrast to local-scale findings highlighting a dominant factor constraining denudation rate,our large-scale quantitative analyses across the Asian mountain belts finds that （1） topographic metrics including

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亚洲高山流域千年尺度地表剥蚀的制约因素

中国科学:地球科学 2024年

作者：杨业 Steven A.BINNIE 徐胜刘丛强 tibor J.DUNAI 天津大学地球系统科学学院表层地球系统科学研究院 Institute of Geology and Mineralogy University of Cologne

本研究利用前人1233个亚洲高山流域沉积物宇宙成因核素10Be数据统一计算了地表剥蚀速率,以约束构造、气候和地形如何影响和控制地表剥蚀过程.基于高程数据逐个像元的核素产率,使用蒙特卡洛模拟方法重新计算了10Be流域剥蚀速率.剥蚀速率... 详细信息

本研究利用前人1233个亚洲高山流域沉积物宇宙成因核素10Be数据统一计算了地表剥蚀速率,以约束构造、气候和地形如何影响和控制地表剥蚀过程.基于高程数据逐个像元的核素产率,使用蒙特卡洛模拟方法重新计算了10Be流域剥蚀速率.剥蚀速率变化范围从（7.4±0.7）mm ka-1（1σ;青藏高原内部）到(9,646744+777)mm ka-1（1σ;青藏高原南部）跨四个数量级,中位数为186mm ka-1.逐个像元计算的核素产率与传统模型使用质心坐标和平均高程计算的核素产率相比,后者96.6%核素产率被低估,其中高程差越大越被低估.两种方法计算的产率偏差可达40%,究其原因可能是流域高程分布不均和核素产率随海拔和纬度呈非线性变化.通过量化地表剥蚀速率与构造、气候、地形和岩性之间的相关性将有助于推演未知流域的剥蚀速率.从局部小尺度分析,亚热带台湾岛地区剥蚀速率可能主要受降水和新构造驱动的山体滑坡影响,而降水变化范围较窄的青藏高原东部的剥蚀速率主要受控于地形;冰川覆盖的高原地区剥蚀速率受冰川作用影响,如帕米尔、青藏高原内部和南部地区;青藏高原内部剥蚀速率较低是因为较低的降水和较高的侵蚀基准面,从而限制了河流的下切和地表起伏度演化.与局部小尺度强调单一主控因素不同,本研究对亚洲高山流域宏观大尺度进行量化分析发现:（1）地形指标（包括坡度、地形起伏度和河道陡峭指数）与剥蚀速率在千年尺度呈现一致的幂函数关系,而非简单线性;（2）剥蚀速率与气候（包括与海拔相关的降水、温度和植被覆盖度）和新构造活动（地震核密度分布）呈近似幂函数关系,为次要控制因素;（3）岩性与剥蚀速率没有明显的相关性,可能受限于流域复杂的岩性混合和低分辨率的可侵蚀指数数据.

关键词： Be剥蚀速率气候变化构造抬升地形梯度亚洲高山流域

An advanced efficient model for adhesive wear in elastic-plastic spherical contact

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Friction 2022年第8期10卷 1276-1284页

作者： Haibo ZHANG izhak ETSION School of Mechanical Engineering Beijing Institute of TechnologyBeijing 100081China Department of Mechanical Engineering TechnionHaifa 32000Israel

A finite element(FE)model combining submodel technique is presented for the adhesive wear in elastic–plastic spherical *** consists of a global model,showing the potential location of fracture under combined normal and tangential loading,and a refined mesh submodel covering only the region near the potential *** allows to describe the morphology of wear particle more accurately than that in a previously developed model by the authors.A range of normal loading is studied to show its effect on the shape and volume of wear *** main regimes of mild and severe wear(along with a relatively narrow transition region between them)are found,which show almost linear and power-law dependency of wear rate on normal loading,*** behavior agrees with published experimental ***,the transition region is theoretically predicted here for the first time.

关键词： spherical contact adhesive wear normal loading power law

Modeling of surface texturing in hydrodynamic lubrication

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Friction 2013年第3期1卷 195-209页

作者： izhak ETSION Department of Mechanical Engineering Technion-Israel Institute of TechnologyHaifa 32000Israel

Theoretical modeling of surface texturing in hydrodynamic lubrication is a necessary first step to obtain favorable effect of the *** invited review presents a comprehensive summary of the modeling of several basic ap... 详细信息

关键词： surface texturing modeling hydrodynamic lubrication

Model for the static friction coefficient in a full stick elastic-plastic coated spherical contact

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Friction 2019年第6期7卷 613-624页

作者： Zhou CHEN izhak ETSION Department of Mechanical Engineering Technion

Finite element analysis is used to investigate an elastic-plastic coated spherical contact in full stick contact condition under combined normal and tangential loading. Sliding inception is associated with a loss of tangential stiffness. The effect of coating thickness on the static friction coefficient is intensively investigated for the case of hard coatings. For this case, with the increase in coating thickness, the static friction coefficient first increases to its maximum value at a certain coating thickness, thereafter decreases, and eventually levels off. The effect of the normal load and material properties on this behavior is discussed. Finally, a model for the static friction coefficient as a function of the coating thickness is provided for a wide range of material properties and normal loading.

关键词： contact mechanics elastic‐plastic contact spherical contact static friction hard coatings

Development of donor specific antibodies after SARS-CoV-2 vaccination:What do we know so far?

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World Journal of Meta-Analysis 2024年第2期12卷 1-4页

作者： Ahmed Daoud Karim Soliman Maria Aurora Posadas Salas Sakshi Vaishnav Genta Uehara AhmedAbdelkader tibor Fulop Michael J Casey Department of Medicine Division of NephrologyMedical University of South CarolinaCharlestonSC 29425United States Department of Medicine Cairo University Medical SchoolCairo 11211Egypt Department of Medicine Medical ServicesRalph H.Johnson VA Medical CenterCharlestonSC 29425United States Department of Medicine Division of NephrologyMedical ServicesRalph H.Johnson VA Medical CenterCharlestonSC 29425United States

Vaccination against Coronavirus disease-19(COVID-19)was pivotal to limit spread,morbidity and *** aim is to find out whether vaccines against COVID-19 lead to an immunological response stimulating the production of de novo donor specific antibodies(DSAs)or increase in mean fluorescence intensity(MFI)of pre-existing DSAs in kidney transplant recipients(KTRs).This study involved a detailed literature search through December 2nd,2023 using PubMed as the primary *** search strategy incorporated a combination of relevant Medical Subject Headings terms and keywords:"COVID-19","SARS-CoV-2 Vaccination","Kidney,Renal Transplant",and"Donor specific antibodies".The results from related studies were collated and analyzed.A total of 6 studies were identified,encompassing 460 KTRs vaccinated against *** responses were detected in 8 KTRs of which 5 had increased MFIs,1 had de novo DSA,and 2 were categorized as either having de novo DSA or increased *** were 48 KTRs with pre-existing DSAs prior to vaccination,but one study(Massa et al)did not report whether pre-existing DSAs were associated with post vaccination *** the remaining 5 studies,35 KTRs with pre-existing DSAs were identified of which 7 KTRs(20%)developed de novo DSAs or increased ***,no immunological response was detected in 452(98.3%)*** study affirms prior reports that COVID-19 vaccination is safe for KTRs,especially if there are no pre-existing ***,if KTRs have pre-existing DSAs,then an increased immunological risk may be *** findings need to be taken cautiously as they are based on a limited number of patients so further studies are still needed for confirmation.

关键词： COVID-19 SARS-CoV-2 vaccination Kidney Renal transplant Donor specific antibodies

A comparison of stick and slip contact conditions for a coated sphere compressed by a rigid flat

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Friction 2017年第3期5卷 326-338页

作者： Shai RONEN Roman GOLTSBERG izhak ETSION Department of Mechanical Engineering Technion Haifa 32000 Israel

A finite element analysis is used to study the elastic-plastic contact of a coated sphere compressed by a rigid flat under the stick contact *** was done for a wide range of hard coating material properties and coating thicknesses.A comparison with the slip contact condition is presented in terms of the critical contact parameters (at yield inception) and plasticity *** expressions are provided for critical interferences of the first and second yield inceptions,in the coating and on the substrate side of the interface,*** expression is also provided for the dimensionless coating thickness for optimal resistance to plasticity under the stick contact ***,the relations between different contact parameters in the elastic-plastic regime are *** general,it was found that the contact condition has a negligible effect on the contact parameters,except for phenomena occurring close to the contact area.

关键词： contact mechanics coatings stick elastic-plastic