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Neural Regeneration Research 2015年第4期10卷 594-598页

作者： Zhen Feng Ying-jun Zhong Liang Wang tian-qi wei Department of Rehabilitation Medicine the First Affiliated Hospital of Nanchang University

In this study, rats were put into traumatic brain injury-induced coma and treated with median nerve electrical stimulation. We explored the wake-promoting effect, and possible mechanisms, of median nerve electrical stimulation. Electrical stimulation upregulated the expression levels of orexin-A and its receptor OX1R in the rat prefrontal cortex. Orexin-A expression gradually in-creased with increasing stimulation, while OX1R expression reached a peak at 12 hours and then decreased. In addition, after the OX1R antagonist, SB334867, was injected into the brain of rats after traumatic brain injury, fewer rats were restored to consciousness, and orexin-A and OXIR expression in the prefrontal cortex was downregulated. Our ifndings indicate that median nerve electrical stimulation induced an up-regulation of orexin-A and OX1R expression in the pre-frontal cortex of traumatic brain injury-induced coma rats, which may be a potential mechanism involved in the wake-promoting effects of median nerve electrical stimulation.

关键词： nerve regeneration traumatic brain injury coma median nerve electrical stimulation wake-promoting orexin-A OX1R NSFC grants neural regeneration

Mn(Ⅲ)-mediated radical cascade reaction of boronic acids with isocyanides:Synthesis of diimide derivatives

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Chinese Chemical Letters 2019年第2期30卷 379-382页

作者： Fei Wang tian-qi wei Pei Xu Shun-Yi Wang Shun-Jun Ji Key Laboratory of Organic Synthesis of Jiangsu Province College of ChemistryChemical Engineering and Materials Science ξ Collaborative Innovation Center of Suzhou Nano Science and Technology Soochow University

A manganese (Ⅲ)-promoted oxidative radical cascade reaction of easily accessible arylboronic acids with isocyanides to construct diimide derivatives was studied. This protocol provides a new way to synthesis of acety... 详细信息

关键词： Mn(OAc)3 Isocyanide Arylboronic acid Diimide derivatives Radical cascade

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新经济背景下食用菌市场营销目标差异化定位

中国食用菌 2020年第6期39卷 165-168页

作者：田琦玮上海理工大学管理学院上海200093

为了更好地满足消费者对食用菌的需求和提高食用菌企业销售能力,针对新经济背景下食用菌市场营销目标差异化定位进行分析。通过调查问卷的形式了解食用菌消费人群的消费行为,最终将消费者划分为节俭型、享受型、谨慎型、健康型,并分析... 详细信息

为了更好地满足消费者对食用菌的需求和提高食用菌企业销售能力,针对新经济背景下食用菌市场营销目标差异化定位进行分析。通过调查问卷的形式了解食用菌消费人群的消费行为,最终将消费者划分为节俭型、享受型、谨慎型、健康型,并分析了每种类型消费者的消费心理。基于消费心理调研,提出食用菌市场营销目标差异化定位和策略。分别从营养角度、安全角度、生态角度确立食用菌市场营销目标定位:绿色健康、生态且无污染,高营养且无公害的产品;从品牌策略和营销组合方面给出了销售对策:以产品、价格、渠道、促销、网络销售策略等为营销组合,实现食用菌高效销售。

关键词：新经济食用菌市场营销目标差异化定位

棒束通道内定位格架的两相流动局部阻力实验研究

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原子能科学技术 2015年第2期49卷 279-284页

作者：闫超星阎昌琪孙立成田齐伟哈尔滨工程大学核安全与仿真技术国防重点学科实验室黑龙江哈尔滨150001

在常温、常压条件下,对竖直3×3棒束通道内定位格架的单相及两相局部阻力特性进行了实验研究。单相流动实验时,水雷诺数的变化范围为290-18 007;两相实验时,气相、液相表观速度变化范围分别为0.013-3.763m/s和0.076-1.792m/s。利用单相... 详细信息

在常温、常压条件下,对竖直3×3棒束通道内定位格架的单相及两相局部阻力特性进行了实验研究。单相流动实验时,水雷诺数的变化范围为290-18 007;两相实验时,气相、液相表观速度变化范围分别为0.013-3.763m/s和0.076-1.792m/s。利用单相实验数据得到的定位格架局部阻力系数计算关系式,用两相实验数据对均相流模型中8种不同的两相等效黏度计算方法进行了评价。Re1〈9000时,Dukler模型的预测效果最好;Re1≥9000时,McAdams计算方法预测效果最好;基于所有数据,Dukler模型的计算值与实验值吻合最好,平均相对误差为29.03%。考虑了质量含气率、两相雷诺数及气液相密度的影响,对Re1〈9000时的实验数据进行了拟合,得到的经验关系式的计算值与实验值符合较好。

关键词：棒束通道定位格架单相流两相流局部阻力特性

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棒束通道内两相流动摩擦阻力特性分析

原子能科学技术 2015年第5期49卷 819-824页

作者：田齐伟阎昌琪孙立成闫超星哈尔滨工程大学核安全与仿真技术国防重点学科实验室黑龙江哈尔滨150001

常温常压下,对竖直3×3棒束通道内气液两相流动阻力特性进行了实验研究。利用所获得的实验数据,对8种典型的两相流动摩擦压降计算模型进行了评价。结果表明,均相模型在两相流速较高时精度较高,在两相流速较低时则偏差较大。分相模型中,F... 详细信息

常温常压下,对竖直3×3棒束通道内气液两相流动阻力特性进行了实验研究。利用所获得的实验数据,对8种典型的两相流动摩擦压降计算模型进行了评价。结果表明,均相模型在两相流速较高时精度较高,在两相流速较低时则偏差较大。分相模型中,Friedel模型和Lombodi-Pedrocchi模型不适用于本实验条件下棒束通道内气液两相流动摩擦压降的计算。Chisholm C模型、Zhang-Mishima模型、ChisholmB模型、Mishima-Hibiki模型及***模型的预测值与实验值的平均相对误差介于20%~30%之间。基于实验数据,通过修正ChisholmC模型的C系数,给出一个新的修正模型,其计算值与实验值符合良好。

关键词：棒束通道两相流动摩擦阻力 ChisholmC模型

Solidification of nanostructured lipid carrier onto pellets by fluid-bed coating:preparation,in vitro characterization and bioavailability in dogs

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Solidification of nanostructured lipid carrier onto pellets ...

并行产品设计人员学习与交流能力对下游活动影响的研究

2012年中国药物制剂大会——中国药学会药剂专业委员会年会、亚洲阿登制药技术研讨会暨国际控释协会中国分会年会

作者： Zhiqiang tian.Jianping qi,wei Wu~* Department of pharmaceutics,school of pharmacy,Fudan University,Shanghai 201201,P.R.China

Previous studies have demonstrated that nanostructured lipid carrier(NLC)is a promising system for poorly water-soluble drugs delivery with improved *** NLC,however,is mostly prepared in a liquid form,which has some disadvantages:drug expulsion during storage,thermodynamic instability and high water content of NLC suspension. Therefore,the conversion of the NLC suspension into a dry product is necessary. The present work investigates fluid-bed coating as a new technique to prepare a pellet-based NLC of *** suspension was prepared by high pressure homogenization and the physicochemical properties of nanocarriers were *** were selected to entrap NLC as the matrix of coating *** electron microscopic was used to characterize the morphology of both the surface and cross-section of the solidified NLC pellets and using powder x-ray diffraction analysis and differential scanning calorimeter(DSC)identify the physical state of fenofibrate in solidified NLC *** capacity of the coating layer to entrap NLC and the redispersion of NLC from solidified NLC pellets were also ***,in vivo absorption of both solidified NLC pellets and NLC suspension in dogs was evaluated. Solidified NLC pellets were successfully prepared by a fluid-bed coating technique with good surface properties observing by scanning electron ***,obtained with small particle size and good size distribution,can be entrapped with PVP-K17 to get good quality of solidified NLC pellets in *** optimized solidified NLC pellets was prepared by single factor test,in which the coated weight was 100%,drug loading 5.6%in NLC,and NLC suspension agent 67%.Powder x-ray diffraction analysis and DSC confirmed nonexistence of crystalline fenofibrate in the *** redispersed readily from solidified NLC pellets at high rate within about 15 min to arrive high cumulative redispersion extent achieving over 90%.The particl

关键词： solidification nanostructured lipid carrier fluid-bed coating poorly water-soluble drugs bioavailability

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工程设计学报 2016年第5期23卷 424-430页

作者：田启华汪巍巍杜义贤董群梅文小勇三峡大学机械与动力学院湖北宜昌443002

设计人员的学习与交流能力是影响并行产品开发的重要因素.为了研究设计人员学习与交流能力对下游设计活动的影响,构建了学习知识量函数与返工率函数,提出了下游设计活动启动时刻与设计活动间信息交流次数的数学模型,研究了设计人员学习... 详细信息

设计人员的学习与交流能力是影响并行产品开发的重要因素.为了研究设计人员学习与交流能力对下游设计活动的影响,构建了学习知识量函数与返工率函数,提出了下游设计活动启动时刻与设计活动间信息交流次数的数学模型,研究了设计人员学习与交流能力对下游设计活动启动时刻及设计活动间信息交流次数的影响,得出了下游设计活动启动时刻与设计活动间信息交流次数的判断条件,并通过实例对判断条件进行了分析验证.根据判断条件以及设计人员学习与交流能力指数,计算出下游设计活动启动时刻与设计活动间信息交流次数.研究结果为缩短产品开发时间与减少产品开发成本提供了理论参考.

关键词：并行产品开发学习能力交流能力启动时刻信息交流次数

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熄焦车箱的技术改造

机械管理开发 2013年第5期28卷 59-60页

作者：田其伟山西省焦炭集团龙源园区焦化有限公司山西介休032000

通过生产中遇到数次对熄焦车箱的检修与抢修,经过多次对熄焦车箱的制作经验,不断摸索,对熄焦车箱实施几处技改,从而降低对车箱的维修频率,提高车箱的使用寿命,降低生产成本。

关键词：熄焦车车箱技术改造降低维修频率提高使用寿命降低生产成本

A novel active-passive protection strategy endows carbonyl iron with excellent intelligent anti-corrosion and microwave absorption dual functional characteristics

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Nano Research 2025年第1期18卷 487-500页

作者： wei tian Quanyuan Feng Linbo Zhang Yinfan Liu Xian Jian Longjiang Deng Institute of Microelectronics School of Information Science and TechnologySouthwest Jiaotong UniversityChengdu 611756China National Engineering Researching Centre of Electromagnetic Radiation Control Materials Key Laboratory of Multi-Spectral Absorbing Materials and Structures of Ministry of EducationState Key Laboratory of Electronic Thin Films and Integrated DevicesSchool of Electronic Science and EngineeringUniversity of Electronic Science and Technology of ChinaChengdu 611731China School of Materials and Energy University of Electronic Science and Technology of ChinaChengdu 611731China The Yangtze Delta Region Institute(Huzhou)&School of Electronic Science and Engineering University of Electronic Science and Technology of ChinaHuzhou 313001China

Carbonyl iron absorbers(CI)face significant challenges in practical applications,such as corrosion,interface bonding failure,detachment,and high maintenance ***,we have developed intelligent self-healing technology based on proactive/passive mechanisms via in situ synthesis of self-healing factors(polydopamine/benzotriazole(PDA/BTA))and physical barrier layers(SiO_(2)/1,1,1,3,3,3-hexamethyl disilazane,SiO_(2)/HMDS)to enhance corrosion resistance,while also being compatible with efficient microwave absorption *** unique multiscale structure gives full play to the utilization of the roles of each functional layer,including the intelligent self-healing features of PDA/BTA,physical shielding and spatial confinement characteristics of SiO_(2)/HMDS,and magnetic-dielectric synergistic mechanism resulted from the good impedance matching characteristics,the conduction loss,the interfacial polarization loss and natural *** asfabricated composites achieved an exceptional minimum reflection loss value of-55.4 dB at 10.7 GHz and the effective absorption band of 7.6 ***,it still exhibits obvious self-healing and corrosion resistance characteristics after 360 h corrosion treatment,ascribed to the self-healing mechanism of PDA/BTA and the blocking intervention effect of SiO_(2)/*** work is considered to pave the way for the synthesis of high-performance magnetic absorbers,especially in enhancing their intelligent self-healing ability in corrosive environments.

关键词： microwave absorption intelligent self-healing technology carbonyl iron multiscale structure magneticdielectric synergistic mechanism

Metal nanoparticles decorated CoFe-(oxy)hydroxysulfides nanosheets fabricated by a general strategy for electrocatalytic water splitting

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Journal of Energy Chemistry 2025年第1期100卷 26-38页

作者： Xiaodong Yang Haochen Shen Xiaoming Xiao Zhichao Li qi Zhou wei Yang Bin Jiang Yongli Sun Luhong Zhang Zhenhua Yan School of Chemical Engineering and Technology Tianjin University Key Laboratory of Advanced Energy Materials Chemistry (Ministry of Education) Nankai University

This study presents a novel method to fabricate metal-decorated,sulfur-doped layered double hydroxides （M/SLDH） through spontaneous redox and sulfurization *** developed Ag/SLDH and Pt/SLDH catalysts with abundant heterogeneous interfaces and hierarchical nanostructures demonstrated outstanding oxygen evolution reaction （OER） and hydrogen evolution reaction （HER） performance,achieving low overpotentials of 212 and 35 mV at 10 mA cm-2in 1 M KOH,*** both anode and cathode in water splitting,they required only 1.47 V to reach 10 mA cm-2and exhibited high structural robustness,maintaining stability at 1000 mA cm-2for 300 ***-situ Raman analysis revealed that the synergistic effects of metal nanoparticles and S doping significantly promote the transformation into the S-Co1-xFexOOH layer,which serves as the active phase for water ***,ultraviolet photoelectron spectroscopy （UPS） and density functional theory （DFT） analyses indicated that incorporating metal nanoparticles and S doping increase electron density near the Fermi level and reduce reaction energy barriers,thus enhancing intrinsic OER and HER *** study provides a scalable strategy for synthesizing high-performance electrocatalysts for water splitting,with promising potential for broader applications.

关键词： LDH Spontaneous reaction Metal nanoparticles Water splitting