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Phase-field model of precipitation processes with coherency loss

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npj Computational Materials 2021年第1期7卷 338-348页

作者： tian-le Cheng You-Hai Wen National Energy Technology Laboratory AlbanyORUSA leidos Research Support Team AlbanyORUSA

A phase-field model is proposed to simulate coherency loss coupled with microstructure evolution.A special field variable is employed to describe the degree of coherency loss of each particle and its evolution is governed by a Ginzburg-Landau type kinetic *** the sake of computational efficiency,a flood-fill algorithm is introduced that can drastically reduce the required number of field variables,which allows the model to efficiently simulate a large number of particles sufficient for characterizing their statistical features during Ostwald *** model can incorporate size dependence of coherency loss,metastability of coherent particles,and effectively incorporate the underlying mechanisms of coherency loss by introducing a so-called differential energy *** model is applied to simulate coarsening of Al3Sc precipitates in aluminum alloy and comprehensively compared with *** results clearly show how the particle size distribution is changed during coherency loss and affects the coarsening rate.

关键词： coherency alloy microstructure

Review on Fault-Tolerant NoC Designs

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Journal of Electronic Science and Technology 2018年第3期16卷 191-221页

作者： Jun-Shi Wang le-tian Huang the School of Electronic Science and Engineering University of Electronic Science and Technology of ChinaChengdu 611731 Beijing Zhaoxin Electronic Technology Co. Ltd.Beijing 100084 the School of Electronic Science and Engineering University of Electronic Science and Technology of ChinaChengdu 610054

By benefiting from the development of the semiconductor technology, many-core system-on-chips(SoCs)have been widely used in electronic devices. Network-on-chips(NoCs) can address the massive stress of on-chip communications due to the advantages of high bandwidth, low latency, and good flexibility. Since deep sub-micron era, the reliability has become a critical constraint for integrated circuits. To provide correct data transmission, faulttolerant NoCs have been researched widely in last decades, and many valuable designs have been proposed. This work introduces and summarizes the state-of-the-art technologies for fault diagnosis and fault recovery in faulttolerant NoCs. Moreover, this work makes prospects for the future’s research.

关键词： Fault diagnosis fault recovery fault-tolerant network-on-chip

Emerging approaches to probing ion channel structure and function

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Neuroscience Bulletin 2012年第4期28卷 351-374页

作者： Wei-Guang Li tian-le Xu Neuroscience Division Department of Biochemistry and Molecular Cell BiologyInstitute of Medical SciencesShanghaiJiao Tong University School of MedicineShanghai 200025China

Ion channels,as membrane proteins,are the sensors of the *** act as the first line of communication with the world beyond the plasma membrane and transduce changes in the external and internal environments into unique electrical signals to shape the responses of excitable *** of their importance in cellular communication,ion channels have been intensively studied at the structural and functional ***,we summarize the diverse approaches,including molecular and cellular,chemical,optical,biophysical,and computational,used to probe the structural and functional rearrangements that occur during channel activation（or sensitization）,inactivation（or desensitization）,and various forms of *** emerging insights into the structure and function of ion channels by multidisciplinary approaches allow the development of new pharmacotherapies as well as new tools useful in controlling cellular activity.

关键词： ion channel structure and function mutagenesis covalent modification voltage-clamp fluorometry computational chemistry

Cell-Type Identification in the Autonomic Nervous System

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Neuroscience Bulletin 2019年第1期35卷 145-155页

作者： Di-Shi Liu tian-le Xu Department of Anatomy and Physiology Shanghai Jiao Tong University School of Medicine

The autonomic nervous system controls various internal organs and executes crucial functions through sophisticated neural connectivity and circuits. Its dysfunction causes an imbalance of homeostasis and numerous human disorders. In the past decades, great efforts have been made to study the structure and functions of this system, but so far, our understanding of the classification of autonomic neuronal subpopulations remains limited and a precise map of their connectivity has not been *** of the major challenges that hinder rapid progress in these areas is the complexity and heterogeneity of autonomic neurons. To facilitate the identification of neuronal subgroups in the autonomic nervous system, here we review the well-established and cutting-edge technologies that are frequently used in peripheral neuronal tracing and profiling, and discuss their operating mechanisms, advantages, and targeted applications.

关键词： Autonomic nervous system Neuronal tracing Genetic marker Molecular profiling Cell-type diversity

Proton production,regulation and pathophysiological roles in the mammalian brain

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Neuroscience Bulletin 2012年第1期28卷 1-13页

作者： Wei-Zheng Zeng tian-le Xu Neuroscience Division Department of Biochemistry and Molecular Cell Biology Institute of Medical Sciences ShanghaiJiao Tong University School of Medicine Shanghai 200025 China Institute of Neuroscience and State Key Laboratory of Neuroscience Shanghai Institutes for Biological Sciences ChineseAcademy of Sciences Shanghai 200031 China

The recent demonstration of proton signaling in C. elegans muscle contraction suggests a novel mechanism for proton-based intercellular communication and has stimulated enthusiasm for exploring proton signaling in higher organ- isms. Emerging evidence indicates that protons are produced and regulated in localized space and time. Furthermore, identification of proton regulators and sensors in the brain leads to the speculation that proton production and regulation may be of major importance for both physiological and pathological functions ranging from nociception to learning and memory. Extracellular protons may play a role in signal transmission by not only acting on adjacent ceils hut also af- fecting the cell from which they were released. In this review, we summarize the upstream and downstream pathways of proton production and regulation in the mammalian brain, with special emphasis on the proton extruders and sensors that are critical in the homeostatic regulation of pH, and discuss their potential roles in proton signaling under normal and pathophysiological conditions.

关键词： proton extruders proton sensors pH homeostasis proton signaling pH microdomains local accumulation

Unraveling the Mechanisms of Memory Extinction

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Neuroscience Bulletin 2018年第2期34卷 385-388页

作者： Shao-Ling Han tian-le Xu Collaborative Innovation Center for Brain Science Department of Anatomy and Physiology Shanghai Jiao Tong University School of Medicine

Memory is a crucial biological function conserved across almost all *** established and consolidated,a memory is considered stable and long-lasting unless it is disrupted or manipulated by behavioral,physical,or chemi...

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Understanding the Activity Performance of Comets 38P/Stephan-Oterma,64P/Swift-Gehrels and C/2017 M4(ATLAS)through Broadband Photometric Observations

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Research in Astronomy and Astrophysics 2024年第8期24卷 147-156页

作者： Xuan Zhang Jin-Zhong Liu le-tian Wang Xinjiang Astronomical Observatory Chinese Academy of SciencesUrumqi 830011China

In this work,we report observations of three comets:38P/Stephan-Oterma,64P/Swift-Gehrels,and C/2017 M4(ATLAS),conducted with the Nanshan one-meter wide-field telescope in 2018 August and November,and *** extracted morphological features through image enhancement techniques and calculated the dust activity parameter,Afρ,along with dust mass loss rates and coma color indices using broadband photometric *** morphological analysis uncovered a spectrum of dust characteristics among the observed comets,ranging from a significant twisted structure in comet 38P/Stephan-Oterma’s coma to the regular coma envelope surrounding comet 64P/*** Afρvalues varied between 148.8±0.3 cm for 64P/Swift-Gehrels and1118.5±6.2 cm for C/2017 M4(ATLAS)(measured within a reference aperture radius ofρ=6″),indicating a range from moderate to high activity *** mass loss rates were estimated from 328.1 kg s^(-1)for comet 64P/Swift-Gehrels to 1395.5 kg s^(-1)for comet C/2017 M4(ATLAS).The color indices of comets 38P/Stephan-Oterma and C/2017 M4(ATLAS)closely resemble the average colors of active short-period comets and active longperiod comets,*** contrast,64P/Swift-Gehrels exhibits a significantly bluer hue than typical Jupiter family comets.

关键词： comets general-comets individual(38P/Stephan-Oterma,64P/Swift-Gehrels,C/2017 M4(ATLAS))-techniques photometric

Saturation throughput analysis of RTS/CTS scheme in an error-prone WLAN channel

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2009年第12期10卷 1714-1719页

作者： Xiang-yu PENG le-tian JIANG Guo-zhi XU Department of Electronic Engineering Shanghai Jiao Tong University Shanghai 200240 China

In this paper, a new three-dimensional Markov model is proposed for the estimation of saturation throughput of RTS/CTS (request to send/clear to send) scheme in an error-prone wireless local area network (WLAN) channel. The model takes account of the effect of bit error on all the frames, and station short and long retry limits. Saturation throughput was re-analyzed using the new Markov model and numerical results closely matched those from simulation, confirming the accuracy of the new model. Evaluation of the influence of different parameters on throughput showed that the saturation throughput is sensitive to channel bit error rates and packet length, especially in high bit error conditions.

关键词： Saturation throughput RTS/CTS Error-prone WLAN channel Markov model _ _

Pancreatic panniculitis and solid pseudopapillary tumor of the pancreas: A case report

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World Journal of Clinical Cases 2018年第15期6卷 1036-1041页

作者： Meng-Yu Zhang Bo-le tian Department of Pancreatic Surgery West China Hospital/West China School of Medicine Sichuan University Department of Hepatobiliary Surgery the Affiliated Hospital of Southwest Medical University

Solid pseudopapillary tumor of the pancreas(SPTP), also known as solid and papillary epithelial neoplasm of the pancreas, is a rare pancreatic exocrine tumor that is difficult to diagnose before surgery. Pancreatic panniculitis is a rare type that occurs in less than 3% of all patients with pancreatic diseases. We here report a 19-year-old woman who presented with persistent left upper quadrant pain without obvious cause for 1 d. The patient also developed subcutaneous nodules involving lower abdomen bilaterally and lower limbs, and subcutaneous nodules were pathologically diagnosed as pancreatic panniculitis. Plain abdominal computed tomography revealed a soft-tissue mass in the body and tail of the pancreas, which was closely associated with the gastric wall. Contrast-enhanced ultrasound showed inhomogeneous echogenicity in the anterior pancreatic body, which had blurred parenchymal demarcation of the body and tail of the pancreas. Contrast-enhanced abdominal computed tomography revealed a mixed density mass with solid and cystic components in the body and tail of the pancreas, and the solid component was markedly enhanced. The lesion was pathologically diagnosed as SPTP after laparoscopic resection. Clinicians should be aware of the clinical manifestation, diagnosis, and treatment of pancreatic panniculitis and SPTP.

关键词： Case report Pancreatic panniculitis Solid pseudopapillary tumor of the pancreas Subcutaneous nodules Laparoscopy