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Rare Metals 2022年第12期41卷 4104-4115页

作者： Ye-Mao Lin Hao-sen Fan Cai-Zhen Zhu Jian xu College of Chemistry and Environmental Engineering Shenzhen UniversityShenzhen 518060China College of Materials Science and Metallurgy Engineering Guizhou UniversityGuiyang 550025China

Owning to the wide distribution,low cost,and similar chemical-electrochemical properties with lithium,sodium-ion batteries(SIBs) have attracted much attention during recent years and may have the potential to replace the commercial lithium-ion ***,facile and simple bottom-up approach has been rationally applied to fabricate carbon-encapsulated ZnSe@CoSe_(2)micro spheres and Cu_(2)Se@CoSe_(2)*** as-prepared ZnSe@-CoSe_(2)microspheres and Cu_(2)Se@CoSe_(2)nanocubes composites inherited the original structure of ZnCo-MOF and CuCo-MOF,***,both ZnSe@CoSe_(2)micro spheres and Cu_(2)Se@CoSe_(2)nanocubes delivered excellent electrochemical performance when presented as anode materials for *** ZnSe@CoSe2micro spheres and Cu_(2)Se@CoSe_(2)nanocubes electrode could display a long-term cycling stability with a reversible capacity of 525 and 423 mAh·g^(-1)at the current density of 1 A·g^(-1)after 500 cycles,***,even at a high current density of 5 A·g^(-1),ZnSe@CoSe_(2)microsphere could still maintain 520 mAh·g^(-1)after 500 cycles,demonstrating remarkable capacity and excellent cycling *** high performances were beneficial from the unique hollow and porous structure of ZnSe@CoSe_(2)microspheres and Cu_(2)Se@CoSe_(2)nanocubes derived from the precursor which facilitate the transport of sodium ions,contributing to high capacity,improved excellent cycle stability and rate capability.

关键词： Metal selenides Prussian blue analogue Sodium-ion batteries Metal-organic frameworks(MOF)

Risk Factors for Mortality in Critically Ill Patients with Coagulation Abnormalities:A Retrospective Cohort Study

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Current Medical Science 2024年第5期44卷 912-922页

作者： Qiu-yu GUO Jun PENG ti-chao SHAN Miao xu Department of Hematology Qilu Hospital of Shandong UniversityJinan250012China Department of Critical Care Medicine Qilu Hospital of Shandong UniversityJinan250012China

Objective Coagulation abnormalities are common and prognostically significant in intensive care units(ICUs)and are associated with increased *** study aimed to explore the association between the levels of coagulation markers and the risk of mortality among ICU patients with coagulation *** This retrospective study investigated patients with coagulation abnormalities in the ICU between January 2021 and December *** initial point for detecting hemostatic biomarkers due to clinical assessment of coagulation abnormalities was designated day *** were followed up for 28 days,and multivariate logistic regression analysis was utilized to identify risk factors for *** Of the 451 patients analyzed,115 died,and 336 were alive at the end of the 28-day *** analysis revealed that elevated thrombin-antithrombin complex(TAT),tissue plasminogen activator inhibitor complex(tPAIC),prolonged prothrombin time,and thrombocytopenia were independent risk factors for *** nonovert disseminated intravascular coagulation(DIC)patients,older age and thrombocytopenia were associated with increased risks of mortality,whereas elevated levels of plasminα2-plasmin inhibitor complex(PIC)were found to be independent predictors of *** patients with overt DIC,elevated levels of tPAIC were independently associated with increased risks of ***,thrombocytopenia was independently associated with increased risks of mortality in patients with *** Coagulation markers such as the TAT,tPAIC,PIC,and platelet count were significantly associated with mortality,underscoring the importance of maintaining a balance between coagulation and *** findings highlight the potential for targeted therapeutic interventions based on specific coagulation markers to improve patient outcomes.

关键词： blood coagulation markers mortality risk factors disseminated intravascular coagulation intensive care unit

A low redox potential and long life organic anode material for sodium-ion batteries

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Journal of Energy Chemistry 2025年第1期100卷 557-564页

作者： Zhi Li Yang Wei Kang Zhou Xin Huang Xing Zhou Jie xu Taoyi Kong Junwei Lucas Bao Xiaoli Dong Yonggang Wang Department of Chemistry and Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials Institute of New Energy Collaborative Innovation Center of Chemistry for Energy Materials (iChEM) Fudan University Department of Chemistry Boston College School of Materials Science and Engineering Anhui University of Technology

Sodium-ion batteries （SIBs） with organic electrodes are an emerging research direction due to the sustainability of organic materials based on elements like C,H,O,and sodium ***,organic electrode materials for SIBs are mainly used as cathodes because of their relatively high redox potentials（>1 V）.Organic electrodes with low redox potential that can be used as anode are ***,a novel organic anode material （tetrasodium 1,4,5,8-naphthalenetetracarboxylate,Na4TDC） has been developed with low redox potential （tical calculations,showing a high capacity of 208 mAh/g and an average decay rate of merely 0.022%per ***,the Na4TDC-hard carbon composite can further acquire improved capacity and cycling stability for 1200 cycles even with a high mass loading of up to 20 mg *** pairing with a thick Na3V2（PO4）3cathode (20.6 mg cm-2),the as-fabricated full cell exhibited high operating voltage （2.8 V）,excellent rate performance and cycling stability with a high capacity retention of 88.7% after 200 cycles,well highlighting the Na4TDC anode material for SIBs.

关键词： Organic anode material Low redox potential Composite anode Sodium-ion batteries

Inhibition of the cGAS–StiNG pathway:contributing to the treatment of cerebral ischemia-reperfusion injury

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Neural Regeneration Research 2025年第7期20卷 1900-1918页

作者： Hang Yang Yulei Xia Yue Ma Mingtong Gao Shuai Hou Shanshan xu Yanqiang Wang School of Clinical Medicine Shandong Second Medical UniversityWeifangShandong ProvinceChina Department of Emergency The Affiliated Hospital of Weifang Medical UniversityWeifangShandong ProvinceChina Department of Neurology Ⅱ The Affiliated Hospital of Weifang Medical UniversityWeifangShandong ProvinceChina

The cGAS–StiNG pathway plays an important role in ischemia-reperfusion injury in the heart,liver,brain,and kidney,but its role and mechanisms in cerebral ischemia-reperfusion injury have not been systematically ***,we outline the components of the cGAS–StiNG pathway and then analyze its role in autophagy,ferroptosis,cellular pyroptosis,disequilibrium of calcium homeostasis,inflammatory responses,disruption of the blood–brain barrier,microglia transformation,and complement system activation following cerebral ischemia-reperfusion *** further analyze the value of cGAS–StiNG pathway inhibitors in the treatment of cerebral ischemia-reperfusion injury and conclude that the pathway can regulate cerebral ischemia-reperfusion injury through multiple *** of the cGAS–StiNG pathway may be helpful in the treatment of cerebral ischemia-reperfusion injury.

关键词： calcium homeostasis cellular autophagy cerebral ischemia-reperfusion injury cGAS–StiNG pathway ferroptosis gut–brain–microbiota axis inflammatory light chain 3 microglial cells Syntaxin-17 protein

Optimization Strategies of Na_(3)V_(2)(PO_(4))_(3) Cathode Materials for Sodium‑Ion Batteries

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Nano-Micro Letters 2025年第2期17卷 204-251页

作者： Jiawen Hu Xinwei Li Qianqian Liang Li xu Changsheng Ding Yu Liu Yanfeng Gao School of Materials Science and Engineering Shanghai UniversityShanghai 200444People’s Republic of China Shanghai Institute of Ceramics Chinese Academy of SciencesShanghai 200050People’s Republic of China

Na_(3)V_(2)(PO_(4))_(3)(NVP)has garnered great attentions as a prospective cathode material for sodium-ion batteries(SIBs)by virtue of its decent theoretical capacity,superior ion conductivity and high structural ***,the inherently poor electronic conductivity and sluggish sodium-ion diffusion kinetics of NVP material give rise to inferior rate performance and unsatisfactory energy density,which strictly confine its further application in ***,it is of significance to boost the sodium storage performance of NVP cathode *** to now,many methods have been developed to optimize the electrochemical performance of NVP cathode *** this review,the latest advances in optimization strategies for improving the electrochemical performance of NVP cathode material are well summarized and discussed,including carbon coating or modification,foreign-ion doping or substitution and nanostructure and morphology *** foreign-ion doping or substitution is highlighted,involving Na,V,and PO_(4)^(3−)sites,which include single-site doping,multiple-site doping,single-ion doping,multiple-ion doping and so ***,the challenges and prospects of high-performance NVP cathode material are also put *** is believed that this review can provide a useful reference for designing and developing high-performance NVP cathode material toward the large-scale application in SIBs.

关键词： Sodium-ion batteries Na_(3)V_(2)(PO_(4))_(3) Cathode materials Electrochemical performance Optimization strategies

Perfluoropentane-based oxygen-loaded nanodroplets reduce microglial activation through metabolic reprogramming

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Neural Regeneration Research 2025年第4期20卷 1178-1191页

作者： Wanxian Luo Chuanhui xu Linxi Li Yunxiang Ji Yezhong Wang Yingjia Li Yongyi Ye Department of Medicine Ultrasonics Nanfang HospitalSouthern Medical UniversityGuangzhouGuangdong ProvinceChina Institute of Neuroscience Department of NeurosurgeryThe Second Affiliated Hospital of Guangzhou Medical UniversityGuangzhouGuangdong ProvinceChina

Microglia,the primary immune cells within the brain,have gained recognition as a promising therapeutic target for managing neurodegenerative diseases within the central nervous system,including Parkinson’s *** perfluorocarbon droplets have been reported to not only possess a high oxygen-carrying capacity,but also exhibit remarkable anti-inflammatory ***,the role of perfluoropentane in microglia-mediated central inflammatory reactions remains poorly *** this study,we developed perfluoropentane-based oxygen-loaded nanodroplets(PFP-OLNDs)and found that pretreatment with these droplets suppressed the lipopolysaccharide-induced activation of M1-type microglia in vitro and in vivo,and suppressed microglial activation in a mouse model of Parkinson’s *** suppression led to a reduction in the inflammatory response,oxidative stress,and cell migration capacity in ***,the neurotoxic effects were mitigated,which alleviated neuronal ***,ultrahigh-performance liquid chromatography–tandem mass spectrometry showed that the anti-inflammatory effects of PFP-OLNDs mainly resulted from the modulation of microglial metabolic *** further showed that PFP-OLNDs regulated microglial metabolic reprogramming through the AKT-mTOR-HIF-1α***,our findings suggest that the novel PFP-OLNDs constructed in this study alleviate microglia-mediated central inflammatory reactions through metabolic reprogramming.

关键词： metabolic reprogramming microglia microglial migration nanotherapy neurodegenerative diseases neuroinflammation oxygen-loaded nanodroplets Parkinson’s disease perfluoropentane ultra-performance liquid chromatography–mass spectrometry

Delivery methods for CRISPR/Cas9 gene editing in crustaceans

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Marine Life Science & Technology 2020年第1期2卷 1-5页

作者： sen xu Thinh Phu Pham Swatantra Neupane Department of Biology University of Texas at Arlington501 S.Nedderman Dr.ArlingtonTX 76019USA

In this mini-review,we provide an up-to-date overview of the delivery methods that have been used for CRISPR/Cas9 genomic editing in crustacean *** embryonic microinjection as the main workforce for delivering CRISPR/Cas9 reagents,biologists working with crustacean species have to tackle the technical challenges involved in *** use examples of three Crustacean species(the branchiopod Daphnia,amphipod Parhyale hawaiensis,and decapod Exopalaemon carinicauda)to provide a technical guide for embryonic ***,we outline two potentially useful new techniques for delivering CRISPR/Cas9 components into crustaceans,i.e.,Receptor-Mediated Ovary Transduction of Cargo(ReMOT Control)and electroporation.

关键词： Microinjection Electroporation Vitellogenesis Daphnia Parhyale hawaiensis Exopalaemon carinicauda

Effect of Sodium Sulfate on Direct Reduction of Beach titanomagnetite for Separation of Iron and titanium

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Journal of Iron and Steel Research International 2016年第5期23卷 428-433页

作者： En-xia GAO ti-chang SUN Zhi-guo LIU Chao GENG Cheng-yan xu School of Civil and Environmental Engineering University of Science and Technology Beijing

The effect of sodium sulfate on direct reduction of beach titanomagnetite,followed by magnetic separation,to separate iron and titanium was investigated. Direct reduced iron（ DRI） with a high Fe content,low tiO_2 content and low iron recovery was obtained after adding sodium sulfate. When the sodium sulfate dosage was increased from 0 to 10 mass%,the Fe content of the DRI increased from 90. 00 mass% to 93. 55 mass% and the tiO_2 content decreased from 1. 27 mass% to 0. 70 mass%. The reduction mechanism of sodium sulfate was investigated by X-ray diffraction（ XRD） and scanning electron microscopy（ SEM） with energy dispersive spectrometer（ EDS）. Results revealed that the metallic iron grains in the reduced ore with sodium sulfate were larger than those in the ore without sodium sulfate. Sodium sulfate promoted the migration of iron as well as the accumulation and growth of metallic iron grains by low-melting-point carnegieite and troilite formed in the redox system. Low-melting-point carnegieite decreased the melting point of the system and then promoted liquefaction. Troilite could decrease the surface tension and melting point of metallic iron grains.

关键词： beach titanomagnetite sodium sulfate direct reduction separation iron titanium

Long-Term Sunspot Number Prediction based on EMD Analysis and AR Model

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Chinese Journal of Astronomy and Astrophysics 2008年第3期8卷 337-342页

作者： Tong xu Jian Wu Zhen-sen Wu Qiang Li School of Science Xidian University Xi＇an 710071 China National Key Laboratory of Electromagnetic Environment China Research Institute of Radio Wave Propagation Beijing 102206 China IAP University of Rostock Schlosstr. 6 Kuehlungsbom 18225 Germany

The Empirical Mode Decomposition （EMD） and Auto-Regressive model （AR） are applied to a long-term prediction of sunspot numbers. With the sample data of sunspot numbers from 1848 to 1992, the method is evaluated by examining the measured data of the solar cycle 23 with the prediction： different time scale components are obtained by the EMD method and multi-step predicted values are combined to reconstruct the sunspot number time series. The result is remarkably good in comparison to the predictions made by the solar dynamo and precursor approaches for cycle 23. Sunspot numbers of the coming solar cycle 24 are obtained with the data from 1848 to 2007, the maximum amplitude of the next solar cycle is predicted to be about 112 in 2011-2012.

关键词： Sun sunspots- Sun activity

Flow variability along a vegetated natural stream under various sediment transport rates

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Journal of Mountain Science 2018年第11期15卷 2347-2364页

作者： WANG Hai-zhou xu Ze-xing Yu Hai-ti WANG Xie-kang State Key Laboratory of Hydraulics and Mountain River Engineering Sichuan University

The influence of vegetation and sediment on flow characteristics in open channels cannot be neglected. To study the flow variability under the effects of the instream natural vegetation and sediment supply, experiments were conducted with varied water and sediment supply in a movable bed of a river prototype. The instantaneous threedimensional velocities near two types of vegetation patches(the shrub and the weed) and along the centerline of the main channel with vegetation belts were measured using a 3-D side-looking acoustic Doppler velocimetry. The experimental results show that both the instream vegetation and sediment supply strongly affect the flow and turbulence characteristics. In the case of vegetation patches, both the shrub and weed have a considerable influence on the distribution of the streamwise velocity and turbulence intensity of their surrounding water. The streamwise velocity distribution followed as J-shape and linear shape around the weed and shrub under different experimental conditions. The turbulence intensity was large at the top of the weed and shrub;the shrub had its greatest influence on the downstream water flow. In the case of vegetation belts,the streamwise velocity along the centerline of the main channel exhibited an S-shape, J-shape and linear shape at different locations under varied water,vegetation structures and riverbed *** turbulence intensity along the centerline of the main channel ranged from 0.0 to 0.1. The upstream turbulence intensity was affected considerably by a sediment supply, while the downstream turbulence intensity changed with the varied vegetation characteristics and riverbed topography. The second flow coefficient M-value increased longitudinally and was almost positive along the centerline of the main channel, implying that the rotational direction of the secondary current cell was clockwise.

关键词： Natural vegetation Sediment supply Velocity profile Turbulence intensity Secondary flow Movable bed