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Effects of contact/collision sport history on gait in early-to mid-adulthood

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journal of Sport and Health Science 2023年第3期12卷 398-405页

作者： Katherine j.Hunzinger jaclyn B.Caccese rebekah Mannix William P.MeehanⅢ jocelyn F.Hafer C.Buz Swanik thomas A.Buckley Department of Biostatistics Epidemiologyand InformaticsUniversity of Pennsylvania Perelman School of MedicinePhiladelphiaPA 19104USA Penn Injury Science Center University of PennsylvaniaPhiladelphiaPA 19104USA School of Health and rehabilitation Sciences The Ohio State University College of MedicineColumbusOH 43210USA Division of Emergency Medicine Boston Children's HospitalBostonMA 02115USA Departments of Pediatrics and Emergency Medicine Harvard Medical SchoolBostonMA 02115USA The Micheli Center for Sports Injury Prevention WalthamMA 02453USA Division of Sports Medicine Department of OrthopedicsBoston Children's HospitalBostonMA 02453USA Department of Pediatrics and Orthopedics Harvard Medical SchoolBostonMA 02453USA Department of Kinesiology and Applied Physiology University of DelawareNewarkDE 02453USA Interdisciplinary Program in Biomechanics and Movement Science University of DelawareNewarkDE 02453USA

Background:To determine the effect of contact/collision sport participation on measures of single-task(ST)and dual-task(DT)gait among early-to middle-aged ***:The study recruited 113 adults(34.88±11.80 years,(mean±SD);53.0%female)representing 4 *** included(a)former non-contact/collision athletes and non-athletes who are not physically active(n=28);(b)former non-contact/collision athletes who are physically active(n=29);(c)former contact/collision sport athletes who participated in high-risk sports and are physically active(n=29);and(d)former rugby players with prolonged repetitive head impact exposure history who are physically active(n=27).Gait parameters were collected using inertial measurement units during ST and DT *** cost was calculated for all gait parameters(double support,gait speed,and stride length).Groups were compared first using one-way analysis of *** a multiple regression was performed for participants in the highrisk sport athletes and repetitive head impact exposure athletes groups only to predict gait outcomes from contact/collision sport career ***:There were no significant differences between groups on any ST,DT,or DT cost outcomes(p>0.05).Contact/collision sport duration did not predict any ST,DT,or DT cost gait ***:Years and history of contact/collision sport participation does not appear to negatively affect or predict neurobehavioral function in early-to mid-adulthood among physically active individuals.

关键词： Exercise Neurodegenerative disease Postural control rugby Subconcussive impacts

Analysis of PFAAs in American alligators part 2： Potential dietary exposure of South Carolina hunters from recreationally harvested alligator meat

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journal of Environmental Sciences 2017年第11期29卷 31-38页

作者： jessica j.Tipton Louis j.Guillette jr Susan Lovelace Benjamin B.Parrott thomas r.rainwater jessica L.reiner College of Charleston Charleston SC 29724 USA Medical University of South Carolina Department of Obstetrics and Gynecology Charleston SC 29425 USA University of Georgia Odum School of Ecology Savannah River Ecology Laboratory Jackson SC 29831 USA Torn Yawkey Wildlife Center & Belle W. Baruch Institute of Coastal Ecology and Forest Science Clemson University P.O. Box 59(5 Georgetown SC 29442 USA National Institute of Standards and Technology Chemical Sciences Division Hollings Marine Laboratory Charleston SC 29412 USA

Exposure to perfluorinated alkyl acids（PFAAs） has been linked to many harmful health effects including reproductive disorders, developmental delays, and altered liver and kidney function. Most human exposure to environmental contaminants, including PFAAs,occurs through consumption of contaminated food or drinking water. This study uses PFAA data from meat samples collected from recreationally harvested American alligators（Alligator mississippiensis） in South Carolina to assess potential dietary exposure of hunters and their families to PFAAs. Consumption patterns were investigated using intercept surveys of 23 hunters at a wild game meat processor. An exposure scenario using the average consumption frequency, portion size, and median perfluorooctane sulfonic acid（PFOS） concentration in alligator meat from all hunt units found the daily dietary exposure to be 2.11 ng/kg body weight per day for an adult human. Dietary PFOS exposure scenarios based on location of harvest suggested the highest daily exposure occurs with alligator meat from the Middle Coastal hunt unit in South Carolina. Although no samples were found to exceed the recommended threshold for no consumption of PFOS found in Minnesota state guidelines, exposure to a mixture of PFAAs found in alligator meat and site-specific exposures based on harvest location should be considered in determining an appropriate guideline for vulnerable populations potentially exposed to PFAAs through consumption of wild alligator meat.

关键词： Public hunt American alligator Dietary exposure PFOS Consumption advisory Contaminant consumption

Microbial influences on paleoenvironmental changes during the Permian-Triassic boundary crisis

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Science China Earth Sciences 2014年第6期57卷 965-975页

作者： LUO GenMing XIE ShuCheng LIU Deng thomas j. ALGEO State Key Laboratory of Biogeology and Environmental Geology China University of Geosciences

The biosphere interacts and co-evolves with natural *** is known about the biosphere’s response to ancient environmental perturbations,but less about the biosphere’s influences on environmental change through earth ***,we discuss the roles of microbes in environmental changes during the critical Permian-Triassic(P-Tr)transition and present a perspective on future geomicrobiological *** biomarkers,stable isotopic compositions of carbon,nitrogen and sulfur,and mineralogical investigations have shown that a series of microbial functional groups might have flourished during the P-Tr transition,including those capable of sulfate reduction,anaerobic H2S oxidation,methanogenesis,aerobic CH4oxidation,denitrification,and nitrogen *** microbes may have served to both enhance and degrade the habitability of the Earth-surface environment during this *** integrated microbial roles have enabled the Earth’s exosphere to be a self-regulating system.

关键词：古环境变化微生物学二叠系三叠系界线地球历史硫同位素组成厌氧氧化

Analysis of PFAAs in American alligators part 1： Concentrations in alligators harvested for consumption during South Carolina public hunts

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journal of Environmental Sciences 2017年第11期29卷 24-30页

作者： jessica j.Tipton Louis j.Guillette jr Susan Lovelace Benjamin B.Parrott thomas r.rainwater jessica L.reiner College of Charleston Charleston SC 29424 USA Medical University of South Carolina Department of Obstetrics and Gynecology Charleston SC 29425 USA University of Georgia Odum School of Ecology Savannah River Ecology Laboratory Jackson SC 29831 USA Tom Yawkey Wildlife Center & Belle W. Baruch Institute of Coastal Ecology and Forest Science Clemson University P.O. Box 596 Georgetown SC 29442 USA National Institute of Standards and Technology Chemical Sciences Division Hollings Marine Laboratory Charleston SC 29412 USA

Environmental contamination resulting from the production or release of harmful chemicals can lead to negative consequences for wildlife and human health. Perfluorinated alkyl acids（PFAAs） were historically produced as protective coatings for many household items and currently persist in the environment, wildlife, and humans. PFAAs have been linked to immune suppression, endocrine disruption, and developmental toxicity in wildlife and laboratory studies. This study examines the American alligator, Alligator mississippiensis,as an important indicator of ecosystem contamination and a potential pathway for PFAA exposure in humans. Alligator meat harvested in the 2015 South Carolina（SC） public hunt season and prepared for human consumption was collected and analyzed for PFAAs to determine meat concentrations and relationships with animal body size（total length）, sex, and location of harvest. Of the 15 PFAAs analyzed, perfluorooctane sulfonate（PFOS） was found in all alligator meat samples and at the highest concentrations（median 6.73 ng/g）. No relationship was found between PFAA concentrations and total length or *** of one or all compounds varied significantly across sampling locations, with alligators harvested in the Middle Coastal hunt unit having the highest PFOS concentrations（median 16.0 ng/g; p = 0.0001）. Alligators harvested specifically from Berkley County, SC（located in the Middle Coastal hunt unit） had the highest PFOS concentrations and the greatest number of PFAAs detected（p 〈 0.0001）. The site-specific nature of PFAA concentrations in alligator meat observed in this study suggests a source of PFAA contamination in Berkley County, SC.

关键词： Perfluorinated alkyl acids American alligators South Carolina Perfluorooctane sulfonate(PFOS) Dietary exposure

Evaluation of a model for providing cost effective,accessible continuing education to the forensic science community

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Forensic Sciences research 2021年第4期6卷 224-230页

作者： thomas j.Gluodenis Department of chemistry&Physics Lincoln UniversityLincoln UniversityPAUSA

This study presents a detailed model and its subsequent assessment for the development and optimized delivery of continuing education for the forensic science *** continuing education is on the rise as this modality of content dissemination allows for accessibility,convenience,and *** model,which includes an educational needs assessment,gap analysis,online content delivery and archival,was evaluated through the launch of a global training event/symposium *** four-year study of over 6000 participants representing>75 countries provides empirical support for the model based upon registration/attendance data and participant self-assessment *** practices are identified relative to content and format,operational excellence,technology,and financing of the *** directions along with opportunities to further enhance the model are also discussed.

关键词： Forensic sciences continuing education educational requirements online web-based certification

Probing the Impact of Solvent on the Strength of Lewis Acids via Fluorescent Lewis Adducts

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Precision Chemistry 2023年第1期1卷 49-56页

作者： Amy E.Laturski joshua r.Gaffen Paul Demay-Drouhard Christopher B.Caputo thomas Baumgartner Department of Chemistry York UniversityTorontoON M3J 1P3Canada

Various methods have been developed to measure the strength of a Lewis acid.A major challenge for these measurements lies in the complexity that arises from variable solvent interactions and perturbations of Lewis acids as their reaction environment ***,we investigate the impact of solvent effects on Lewis acids for the first time as measured by the fluorescent Lewis adduct(FLA)*** binding of a Lewis acid in various solvents reveals a measurable dichotomy between both polarity and donor ability of the *** not strictly separable,we observe that the influence of solvent polarity on Lewis acid unit(LAU)values is distinctly opposite to the influence of donor *** dichotomy was confirmed by titration data,illustrating that solvation effects can be appropriately and precisely gauged by the FLA method.

关键词： Fluorescence Fluorescent Lewis adducts Lewis acids Effective Lewis acidity Solvent polarity Solvent donor strength

Solid-state emissive biphenylene bridged bisaroyl-S,N-ketene acetals as distinct aggregation-induced enhanced emitters and fluorometric probes

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Aggregate

Aggregate 2021年第5期2卷 179-184页

作者： Lukas Biesen thomas j.j.Muller Institut fur Organische und Makromolekulare Chemie Heinrich-Heine-Universitat DusseldorfDüsseldorfGermany

Biphenylene bridged bisaroyl-S,N-ketene acetals can be readily synthesized by a one-pot Masuda borylation-Suzuki arylation sequence,thus,yielding a library of 20 bisaroyl-S,N-ketene acetals with tunable solid-state emission and aggregationinduced enhanced emission characteristics depending on the para substituents in the starting *** applications as fluorometric probe of alcoholic beverages are outlined.

关键词： aggregation-induced emission aroyl-S N-ketene acetals liquor sensors one-pot reaction solid-state

Prospective,multicentre study of screening,investigation and management of hyponatraemia after subarachnoid haemorrhage in the UK and Ireland

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Stroke & Vascular Neurology 2023年第3期8卷 207-216,I0028-I0059页

作者： james j M Loan Steven Tominey Kirun Baweja julie Woodfield thomas j G Chambers Mark Haley Simran S Kundu H Y josephine Tang Anthony N Wiggins Michael T C Poon Paul M Brennan Translational Neurosurgery The University of Edinburgh Centre for Clinical Brain SciencesEdinburghUK Neurosurgery NHS LothianEdinburghUK Neurosurgery Institute of Neurological SciencesGlasgowUK Department of Medicine School of MedicineDentisty and NuringUniversity of GlasgowGlasgowUK Internal Medicine Queen's UniversityKingstonOntarioCanada Centre for Discovery Brain Sciences University of EdinburghEdinburghUK Edinburgh Centre for Diabetes and Endocrinology NHS LothianEdinburghUK radiology University Hospitals Plymouth NHS TrustPlymouthUK Department of Medicine Cork University HospitalUniversity College CorkCorkIreland

Background Hyponatraemia often occurs after subarachnoid haemorrhage(SAH).However,its clinical significance and optimal management are *** audited the screening,investigation and management of hyponatraemia after *** We prospectively identified consecutive patients with spontaneous SAH admitted to neurosurgical units in the United Kingdom or *** reviewed medical records daily from admission to discharge,21 days or death and extracted all measurements of serum sodium to identify hyponatraemia(re death/dependency at discharge or 21 days and admission duration>10 *** of hyponatraemia with outcome were assessed using logistic regression with adjustment for predictors of outcome after SAH and admission *** assessed hyponatraemia-free survival using multivariable Cox *** 175/407(43%)patients admitted to 24 neurosurgical units developed hyponatraemia.5976 serum sodium measurements were *** osmolality,urine osmolality and urine sodium were measured in 30/166(18%)hyponatraemic patients with complete *** most frequently target daily fluid intake was>3 L and this did not differ during hyponatraemic or non-hyponatraemic episodes.26%(n/N=42/164)patients with hyponatraemia received sodium supplementation.133(35%)patients were dead or dependent within the study period and 240(68%)patients had hospital admission for over 10 *** the multivariable analyses,hyponatraemia was associated with less dependency(adjusted Or(aOr)=0.35(95%CI 0.17 to 0.69))but longer admissions(aOr=3.2(1.8 to 5.7)).World Federation of Neurosurgical Societies grade I-III,modified Fisher 2-4 and posterior circulation aneurysms were associated with greater hazards of *** In this comprehensive multicentre prospective-adjusted analysis of patients with SAH,hyponatraemia was investigated inconsistently and,for most patients,was not associated with changes in management or clinical outcome.T

关键词： admitted urine centre

Patient selection essential in optimizing the benefit of radical prostatectomy for patients with organ-confined prostate cancer

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Asian journal of Andrology 2011年第6期13卷 789-790页

作者： Matthew j resnick thomas j Guzzo The Division of Urology The Hospital of the University of Pennsylvania Philadelphia PA 19104 USA

P rostate cancer is the most common noncutaneous malignancy in the United States and is a highly prevalent disease worldwide in industrialized nations.1 Prostate cancer is also a leading cause of cancer related mortality in the United States with an estimated 32 050 deaths in 2010. If one were to simply look at the raw mortality data,

关键词： Prostate cancer noncutaneous appropriate treatment decisions