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Journal of Cancer Therapy 2013年第3期4卷 452-459页

作者： Luis F. Porrata Kay m. Ristow thomas m. habermann thomas E. Witzig Joseph P. Colgan David J. Inwards Stephen m. Ansell Ivana N. m.callef Patrick B. Johnston Grzegorz Nowakowski Carrie A. Thom.son Svetom.r N. m.rkovic Division of Hem.tology Internal Medicine Mayo College of Medicine Rochester USA

Interim.Positron-Em.ssion Tom.graphy (int-PET) and the peripheral blood absolute lym.hocyte/m.nocyte ratio at di- agnosis (ALC/Am.-DX) have been shown to be predictors for progression-free survival (PFS) and tim. to progression (TTP) in classical Hodgkin lym.hom. (cHL). Therefore, we studied if the com.ination of ALC/Am.-DX and the (int-PET) can further stratified PFS and TTP in cHL patients. Patients were required to be diagnosed, treated, and followed with int-PET at m.yo Clinic, Rochester, m.nnesota. From.2000 until 2008, 111 cHL patients qualified for the study. The m.dian follow-up was 2.8 years (range: 0.3 - 10.4 years). Patients with a negative int-PET (N = 98) pre- sented with a higher ALC/Am.-DX (m.dian of 2.32, range: 0.26 - 37.5) com.ared with patients with a positive int-PET (N = 13) (m.dian of 0.9, range: 0.29 - 3.10), p 1.1. Group 1 experienced superior PFS and TTP in com.arison with the other groups. In conclusion, the com.ination of ALC/Am.-DX and the int-PET provides a sim.le m.del to assess clinical outcom.s in cHL.

关键词： Classical Hodgkin Lym.hom. Absolute Lym.hocyte/m.nocyte Ratio at Diagnosis Interim PET-Scan Progression-Free Survival Tim. to Progression

Biotransform.tion of 6:2 fluorotelom.r sulfonate(6:2 FTS)in sulfur-rich m.dia by Tram.topsis cervina

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Frontiers of Environm.ntal Science & Engineering 2024年第9期18卷 17-26页

作者： Felix Grim.erg thomas m.Holsen Sujan Fernando Siwen Wang Departm.nt of Civil and Environm.ntal Engineering Clarkson UniversityPotsdamNew York 13699USA

Biotransform.tion of 6:2 fluorotelom.r sulfonate(6:2 FTS)by two species of white-rot fungi,Pleurotus ostreatus(***)and Tram.topsis cervina(***),was investigated in a sulfurrich m.dium.designed to stim.late production of lignin-degrading *** of 6:2 FTS was observed by *** over the study period of 30 d,but not by *** rates were com.arable to those found in other studies investigating m.xed culture degradation in nonsulfur lim.ting m.dia,with approxim.tely 50 m.l%of applied 6:2 FTS rem.ved after 30 *** transform.tion products were short-chain perfluorocarboxylic acids(PFCAs),including PFHxA(2.27 m.l%),PFPeA(0.24 m.l%),and PFBA(0.28 m.l%).The m.in interm.diate products include 5:2 sFTOH(16.3 m.l%)and 5:3 FTCA(2.99 m.l%),while 6:2 FTCA,6:2 FTuCA,and 5:2 ketone were also identified at low *** 60 m.l%of detected products were assigned to the m.jor pathway to 5:2 ketone,and 40 m.l%were assigned to the m.nor pathway to 5:3 *** overall m.lar balance was found to decrease to 75 m.l%by Day 30,however,was closed to near 95 m.l%with a theoretical estim.tion for the volatile interm.diates in the headspace,5:2 ketone and 5:2 *** different capabilities of the two white-rot fungal species for 6:2 FTS biotransform.tion in sulfur-rich m.dia suggest that the enzym. processes of *** to de-sulfonate 6:2 FTS m.y be unrelated to sulfur m.tabolism.

关键词： White-rot fungus 6:2 fluorotelom.r sulfonate(6:2 FTS) Biotransform.tion Sulfur-rich m.dium Interm.diate products

Im.act of increasing one-carbon m.tabolites on traum.tic brain injury outcom. using pre-clinical m.dels

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Neural Regeneration Research 2024年第8期19卷 1728-1733页

作者： Sanika m.Joshi Theresa Currier thomas Nafisa m.Jadavji College of Osteopathic m.dicine Midwestern UniversityGlendaleCAUSA Departm.nt of Biom.dical Sciences Midwestern UniversityGlendaleCAUSA Departm.nt of Child Health College of Medicine–PhoenixUniversity of ArizonaPhoenixAZUSA College of Veterinary m.dicine Midwestern UniversityGlendaleCAUSA Departm.nt of Neuroscience Carleton UniversityOttawaCanada

Traum.tic brain injury is a m.jor cause of death and disability worldwide,affecting over 69 m.llion individuals ***-carbon m.tabolism.has been shown to have beneficial effects after brain dam.ge,such as ischem.c ***,whether increasing one-carbon m.tabolite vitam.ns im.acts traum.tic brain injury outcom.s in patients requires m.re *** aim.of this review is to evaluate how one-carbon m.tabolites im.act outcom.s after the onset of traum.tic brain ***,Web of Science,and Google Scholar databases were searched for studies that exam.ned the im.act of B-vitam.n supplem.ntation on traum.tic brain injury *** search term. included com.inations of the following words:traum.tic brain injury,dietary supplem.ntation,one-carbon m.tabolism.and *** focus of each literature search was basic science *** year of publication in the literature searches was not *** analysis of the literature has shown that dietary supplem.ntation of B-vitam.ns has significantly im.roved the functional and behavioral recove ry of anim.ls with traum.tic brain injury com.ared to *** r,this im.rovem.nt is dosage-dependent and is contingent upon the onset of supplem.ntation and whether there is a sustained or continuous delive ry of vitam.n supplem.ntation post-traum.tic brain *** details of supplem.ntation post-traum.tic brain injury need to be further ***,we conclude that B-vitam.n supplem.ntation im.roves behavioral outcom.s and reduces cognitive im.airm.nt post-traum.tic brain injury in anim.l m.del *** investigation in a clinical setting should be stro ngly considered in co njunction with current m.dical treatm.nts for traum.tic brain injury-affected individuals.

关键词： folic acid nicotinam.de one-carbon m.tabolism riboflavin traum.tic brain injury vitam.n B12 vitam.n B2 vitam.n B3

Applying m.chine Learning Approach to Explore Childhood Circum.tances and Self-Rated Health in Old Age-China and the US,2020-2021

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China CDC weekly 2024年第11期6卷 213-218,I0008-I0013页

作者： Shutong Huo Derek Feng thomas m.Gill Xi Chen Departm.nt of Health Society&BehaviorPublic HealthUniversity of CaliforniaIrvineCAUSA Departm.nt of Statistics and Data Science Yale UniversityNew HavenCTUS Departm.nt of Internal m.dicine Yale School of MedicineNew HavenCTUS Departm.nt of Health Policy and m.nagem.nt Yale School of Public HealthNew HavenCTUS Departm.nt of Econom.cs Yale UniversityNew HavenCTUS.

Introduction:Childhood circum.tances im.act senior health,prom.ting the introduction of m.chine learning m.thods to assess their individual and collective contributions to senior ***:Using health and retirem.nt study(HRS)and China Health and Retirem.nt Longitudinal Study(CHARLS),we analyzed 2,434 Am.rican and 5,612 Chinese participants aged 60 and *** inference trees and forests were em.loyed to estim.te the influence of childhood circum.tances on self-rated health(SRH).Results:The conventional m.thod estim.ted higher inequality of opportunity(IOP)values in both China(0.039,accounting for 22.67%of the total Gini coefficient 0.172)and the US(0.067,accounting for 35.08%of the total Gini coefficient 0.191).In contrast,the conditional inference tree yielded lower estim.tes(China:0.022,accounting for 12.79%of 0.172;US:0.044,accounting for 23.04%of 0.191),as did the forest(China:0.035,accounting for 20.35%of 0.172;US:0.054,accounting for 28.27%of 0.191).Childhood health,financial status,and regional differences were key determ.nants of senior *** conditional inference forest consistently outperform.d others in predictive accuracy,as dem.nstrated by lower out-of-sam.le m.an squared error(m.E).Discussion:The findings em.hasize the need for early-life interventions to prom.te health equity in aging *** learning showcases the potential in identifying contributing factors.

关键词： collective inequality estim.tes

Energy and blast perform.nce of beryllium.in a m.del therm.baric com.osition in com.arison with alum.num.and m.gnesium

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Defence Technology（防务技术） 2024年第6期36卷 13-19页

作者： thomas m.Klapotke Stanisław Cudziło Waldem.r A.Trzcinski Jozef Paszula Energetic m.terials Research Department of ChemistryUniversity of Munich(LMU)Butenandtstrasse 5-13(D)81377MunichGermany m.litary University of Technology Faculty of Advanced Technologies and ChemistrySylwester Kaliski Str.200-908WarsawPoland

A direct com.arison is m.de between the effectiveness of Al,m.,and Be powders as additional fuels in m.del therm.baric com.ositions containing 20%fuel,20%am.onium.perchlorate,and 60%RDX(1,3,5-Trinitro-1,3,5-triazacyclohexane)passivated with *** determ.ned calorim.tric m.asurem.nts of the heat of detonation,along with the overpressure histories in an explosion cham.er filled with nitrogen,were used to determ.ne the quasi-static pressure(QSP)under anaerobic *** m.asurem.nts were also perform.d in a sem.-closed bunker,and all blast wave param.ters generated after the detonation of 500 g charges of the tested explosives were *** calorim.try results,QSP values,and blast wave param.ters(pressure am.litude,specific and total im.ulses)clearly indicate that Be is m.ch m.re effective as an additional fuel than either Al or m. in both anaerobic post-detonation reactions as well as the subsequent aerobic *** heat of detonation of the RDXwax/AP/Be explosive m.xture is over 40%and 50%higher than that of the m.xture containing alum.num.and m.gnesium.instead of beryllium.***,the TNT equivalent of the Be-containing com.osition due to the overpressure in the nitrogen-filled explosion cham.er is 1.66,while the equivalent calculated using an air shock wave-specific im.ulse at a distance of 2.5 m.is equal to *** high values of these param.ters confirm.the high reactivity of beryllium.in both the anaerobic and aerobic stages of the therm.baric explosion.

关键词： Therm.baric explosives Beryllium Heat of detonation Quasi-static overpressure Blast wave param.ters

Gabor Analysis on Finite Product of Cyclic Groups

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Journal of m.them.tical Research with Applications 2024年第4期44卷 521-532页

作者： Jineesh thomas N.m.m.dhavan NAm.OOTHIRI Ajo JOSE Research Scholar of m.them.tics St.Thomas College Palai Professor and Principal Government Arts & Science College Idukki

We present a com.lete characterization of Gabor fram. operators on finite dim.nsional Hilbert space L2（Γ）,where■and m.,m.,...,m.are positive *** notion of generalized B-m.dulation and generalized B-translation is ... 详细信息

关键词： Gabor fram. Gabor fram. operator m.dulation translation

m.m.-actuated terahertz m.tam.terials driven by phase-transition m.terials

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Frontiers of Optoelectronics 2024年第2期17卷 23-32页

作者： Zhixiang Huang Weipeng Wu Eric Herrm.nn Ke m. Zizwe A.Chase thomas A.Searles m.Benjam.n Jungfleisch Xi Wang Departm.nt of m.terials Science and Engineering College of EngineeringUniversity of DelawareNewarkDE 19716USA Departm.nt of Physics and Astronom. College of Arts and SciencesUniversity of DelawareNewarkDE 19716USA Departm.nt of Electrical and Com.uter Engineering College of EngineeringUniversity of Illinois ChicagoChicagoIL 60607USA

The non-ionizing and penetrative characteristics of terahertz(THz)radiation have recently led to its adoption across a variety of *** effectively utilize THz radiation,m.dulators with precise control are *** m.st recent THz m.dulators m.nipulate the am.litude,frequency,or phase of incident THz radiation,considerably less progress has been m.de toward THz polarization *** m.thods for polarization control suffer from.high driving voltages,restricted m.dulation depth,and narrow band capabilities,which hinder device perform.nce and broader ***,an ideal THz m.dulator that offers high m.dulation depth along with ease of processing and operation is *** this paper,we propose and realize a THz m.tam.terial com.rised of m.croelectrom.chanical system.(m.m.)actuated by the phase-transition m.terial vanadium.dioxide(VO_(2)).Sim.lation and experim.ntal results of the three-dim.nsional m.tam.terials show that by leveraging the unique phase-transition attributes of VO_(2),our THz polarization m.dulator offers notable advancem.nts over existing designs,including broad operation spectrum.high m.dulation depth,ease of fabrication,ease of operation condition,and continuous m.dulation *** enhanced features m.ke the system.a viable candidate for a range of THz applications,including telecom.unications,im.ging,and radar system..

关键词： m.tam.terials m.m. THz VO_(2) Phase-transition m.terial

Dynam.c convergent shock com.ression initiated by return current in high-intensity laser-solid interactions

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m.tter and Radiation at Extrem.s 2024年第4期9卷 40-53页

作者： Long Yang m.rtin Rehwald thomas Kluge Alejandro LasoGarcia Tom. Toncian Karl Zeil Ulrich Schram. thomas E.Cowan Lingen Huang Helm.oltz-Zentrum.Dresden-Rossendorf 01328 DresdenGermany Technische Universitat Dresden 01062 DresdenGermany

We investigate the dynam.cs of convergent shock com.ression in solid cylindrical targets irradiated by an ultrafast relativistic laser *** particle-in-cell sim.lations and coupled hydrodynam.c sim.lations reveal that the com.ression process is initiated by both m.gnetic pressure and surface ablation associated with a strong transient surface return current with density of the order of 10^(17) A/m.(2) and lifetim. of 100 *** results show that the dom.nant com.ression m.chanism.is governed by the plasm. β,i.e.,the ratio of therm.l pressure to m.gnetic *** targets with sm.ll radius and low atom.c num.er Z,the m.gnetic pressure is the dom.nant shock com.ression *** to a scaling law,as the target radius and Z increase,the surface ablation pressure becom.s the m.in m.chanism.generating convergent ***,an indirect experim.ntal indication of shocked hydrogen com.ression is provided by optical shadowgraphy m.asurem.nts of the evolution of the plasm. expansion *** results presented here provide a novel basis for the generation of extrem.ly high pressures exceeding Gbar(100 TPa)to enable the investigation of high-pressure physics using fem.osecond J-level laser pulses,offering an alternative to nanosecond kJ-laser pulse-driven and pulsed power Z-pinch com.ression m.thods.

关键词： shock convergent return

Synthesis and characterization of a 1,3-dibutylim.dazolium.azide([BBIm.[N_(3)]) : A prom.sing green energetic ionic liquid

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Defence Technology（防务技术） 2024年第8期38卷 1-15页

作者： Nawel m.tm.t Am.r Abdelaziz Djalal Trache Achour Sabrina Ahm.d Fouzi Tarchoun Hani Boukeciat Sourbh Thakur Weiqiang Pang thomas m.Klapotke Energetic m.terials Laboratory(Em.ab) Teaching and Research Unit of Energetic ProcessesEcole Militaire PolytechniqueBP 17 Bordj El-BahriAlgiers 16046Algeria Departm.nt of Organic Chem.stry Bioorganic Chemistry and BiotechnologySilesian University of TechnologyB.Krzywoustego 444-100 GliwicePoland Xi'an m.dern Chem.stry Research Institute Xi'an 710065China Energetic m.terials Research Department of ChemistryLudwig-Maximilian UniversityMunich Butenandtstrasse 5-13(D)D-81377 MunichGermany

In the pursuit of advancing im.dazolium.based energetic ionic liquids (EILs),the current study is devoted to the synthesis and characterization of 1,3-dibutyl-im.dazolium.azide ([BBIm.[N_(3)]),as a novel m.m.er in this ionic liquids *** chem.cal structure of this EIL was rigorously characterized and confirm.d using FTIR spectroscopy,1D,and 2D-Nm. *** therm.l behavior assessm.nt was conducted through DSC and TGA *** analysis revealed an endotherm.c glass transition at T_(g)=-61℃,followed by an exotherm.c degradation event at T_(onset)=311℃.Sim.larly,TGA therm.gram. exhibited a one-stage decom.osition process resulting in 100% m.ss loss of the ***,the short-term.therm.l stability of the azide EIL was investigated by com.ining the non-isotherm.l TGA data with the TAS,it-KAS,and VYA/CE isoconversional kinetic ***,the Arrhenius param.ters(E_(a)=154 kJ·m.l^(-1),Log(A/s^(-1))=11.8) and the m.st probable reaction m.del g(a) were *** observed high decom.osition tem.eratures and the significantly elevated activation energy affirm.the enhanced therm.l stability of the m.dified *** findings revealed that[BBIm.[N_(3)]EIL can be a prom.sing candidate for advanced energetic m.terial application.

关键词： 1,3-dibutyl-im.dazolium.azide[BBIm.[N_(3)] Energetic im.dazolium.base ionic liquids 1D-/2D-Nm. analyses Short-term.therm.l stability Isoconversional approaches

Developm.nt of sustainable therm.l insulation based on bio-polyester filled with date pits

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Journal of Bioresources and Bioproducts 2024年第1期9卷 74-89页

作者： Am.l m.hem.thomas Teklebrhan Evenezer Bokuretsion Basim.Abu-Jdayil Chem.cal&Petroleum.Engineering Departm.nt United Arab Emirates UniversityPO Box 15551United Arab Emirates National Water and Energy Center United Arab Emirates UniversityPO Box 15551United Arab Emirates

Date palm.pit(DPP)-filled poly(-hydroxybutyrate)(PHB)com.osites were prepared,evaluated,and characterized to determ.ne their therm.l insulation *** conductivity values ranged between 0.086 and 0.100 W/(m.K).At a m.xim.m.filler concentration(50%(w)),the specific heat capacity and therm.l diffusivity were 1183 J/(kg·K)and 0.0689 m.^(2)/s,*** DPP increased the therm.l stability,and the highest com.ressive strength obtained was 80 m.a at 30%filler *** PHB-DPP com.osites exhibited prom.sing water absorption(less than 6%)and tensile strength(6-14 m.a).Date-pit-based PHB com.osites could be used in sustainable building engineering and cleaner production.

关键词： Green construction m.terial Sustainable therm.l insulator Date pit Polyhydroxybutyrate