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Anti-N-methyl-D-aspartate receptor-associated encephalitis: A review of clinicopathologic hallmarks and multimodal imaging manifestations

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World Journal of Radiology 2024年第1期16卷 1-8页

作者： Bryce David Beutler Alastair e Moody Jerry Mathew thomas Benjamin Phillip Sugar Mark B Ulanja Daniel Antwi-Amoabeng Lucas Anthony Tsikitas Department of Radiology University of Southern CaliforniaKeck School of MedicineLos AngelesCA 90033United States Department of Anesthesiology University of UtahSalt Lake CityUT 84132United States Department of Internal Medicine Christus Ochsner St.Patrick HospitalLake CharlesLA 70601United States

Anti-N-methyl-D-aspartate receptor-associated encephalitis(NMDARe)is a rare immune-mediated neuroinflammatory condition characterized by the rapid onset of neuropsychiatric symptoms and autonomic *** mechanism of pathogenesis remains incompletely understood,but is thought to be related to antibodies targeting the GluN1 subunit of the NMDA receptor with resultant downstream dysregulation of dopaminergic *** adults are most frequently affected;the median age at diagnosis is 21 *** is a strong female predilection with a female sex predominance of 4:*** often develops as a paraneoplastic process and is most commonly associated with ovarian ***,NMDARe has also been described in patients with small cell lung cancer,clear cell renal carcinoma,and other benign and malignant *** is based on correlation of the clinical presentation,electro-encephalography,laboratory studies,and *** tomography,positron emission tomography,and magnetic resonance imaging are essential to identify an underlying tumor,exclude clinicopathologic mimics,and predict the likelihood of long-term functional *** imaging may be of value for prognostication and to assess the response to *** may involve high-dose corticosteroids,intravenous immunoglobulin,and plasma ***,we review the hallmark clinicopathologic features and imaging findings of this rare but potentially devastating condition and summarize diagnostic criteria,treatment regimens,and proposed pathogenetic mechanisms.

关键词： Anti-N-methyl-D-aspartate receptor-associated encephalitis Autoimmune encephalitis encephalitis Ovarian teratoma Paraneoplastic syndrome Teratoma

Ion emission from warm dense matter produced by irradiation with a soft x-ray free-electron laser

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Matter and Radiation at extremes 2024年第1期9卷 71-84页

作者： Josef Krása Tomás Burian Vera Hájková Jaromír Chalupský Šimon Jelínek Katerina Frantálová Michal Krupka Zuzana Kuglerová Sushil Kumar Singh Vojtech Vozda Ludek Vysín MichalŠmíd Pablo Perez-Martin Marion Kühlman Juan Pintor Jakub Cikhardt Matthias Dreimann Dennis eckermann Felix Rosenthal Sam M.Vinko Alessandro Forte thomas Gawne thomas Campbell Shenyuan Ren YuanFeng Shi Trevor Hutchinson Oliver Humphries thomas Preston Mikako Makita Motoaki Nakatsutsumi Xiayun Pan Alexander Köhler Marion Harmand Sven Toleikis Katerina Falk Libor Juha Department of Radiation and Chemical Physics Institute of PhysicsCzech Academy of SciencesNa Slovance 218221 Prague 8Czech Republic Laser Plasma Department Institute of Plasma PhysicsCzech Academy of SciencesZa Slovankou 318200 Prague 8Czech Republic Department of Surface and Plasma Science Faculty of Mathematics and PhysicsCharles University in PragueV Holesovi ckách 218000 Prague 8Czech Republic Department of Physical electronics Faculty of Nuclear Science and Engineering PhysicsCzech Technical University in PragueV Holesovi ckách 218000 Prague 8Czech Republic Helmholtz-Zentrum Dresden-Rossendorf Bautzner Landstraße 40001328 DresdenGermany DeSY Photon Science Notkestraße 85D-22607 HamburgGermany Institut de Minéralogie de Physique des Matériaux et de CosmochimieUMR 7590–UPMC/CNRS/IRD/MNHNSorbonne Université4 place Jussieu75005 ParisFrance Department of Physics Faculty of Electrical EngineeringCzech Technical University in PragueTechnická216627 Prague 6Czech Republic Center for Soft Nanoscience University of MünsterBusso-Peus-Straße 10D-48149 MünsterGermany Department of Physics Clarendon LaboratoryUniversity of OxfordParks RoadOxford OX13PUUnited Kingdom Central Laser Facility STFC Rutherford Appleton LaboratoryDidcot OX110QXUnited Kingdom Lawrence Livermore National Laboratory 7000 East AvenueLivermoreCalifornia 94550USA european XFeL GmbH Holzkoppel 4D-22869 SchenefeldGermany Technische Universität Dresden 01062 DresdenGermany

We report on an experiment performed at the FLASH2 free-electron laser(FeL)aimed at producing warm dense matter via soft x-ray isochoric *** the experiment,we focus on study of the ions emitted during the soft x-ray ablation process using time-of-flight electron multipliers and a shifted Maxwell–Boltzmann velocity distribution *** find that most emitted ions are thermal,but that some impurities chemisorbed on the target surface,such as protons,are accelerated by the electrostatic field created in the plasma by escaped *** morphology of the complex crater structure indicates the presence of several ion groups with varying *** find that the ion sound velocity is controlled by the ion temperature and show how the ion yield depends on the FeL radiation attenuation length in different materials.

关键词： electrostatic emitted chemi

Modulating p-type doping of two-dimensional material palladium diselenide

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Nano Research 2024年第4期17卷 3232-3244页

作者： Jiali Yang Yu Liu en-Yang Wang Jinbo Pang Shirong Huang thomas Gemming Jinshun Bi Alicja Bachmatiuk Hao Jia Shu-Xian Hu Chongyun Jiang Hong Liu Gianaurelio Cuniberti Weijia Zhou Mark H Rümmeli Institute for Advanced Interdisciplinary Research(iAIR) University of JinanJinan 250022China Institute for Materials Chemistry Leibniz Institute for Solid State and Materials Research Dresden(IFW Dresden)20 Helmholtz StrasseDresden 01069Germany State Key Lab of Transducer Technology Shanghai Institute of Microsystem and Information TechnologyChinese Academy of SciencesShanghai 200050China College of energy Soochow Institute for Energy and Materials Innovations Soochow UniversitySuzhou 215006China Key Laboratory of Advanced Carbon Materials and Wearable energy Technologies of Jiangsu Province Soochow UniversitySuzhou 215006China School of Integrated Circuits University of Chinese Academy of SciencesBeijing 101408China Institute of Microelectronics of Tianjin Binhai New Area Tianjin 300451China Institute of Microelectronics Chinese Academy of SciencesBeijing 100029China Lukasiewicz Research Network PORT Polish Center for Technology DevelopmentStablowicka 147Wroclaw 54-066Poland School of Mathematics and Physics University of Science and Technology BeijingBeijing 100083China College of electronic information and optical engineering Nankai UniversityTianjin 300350China Centre of Polymer and Carbon Materials Polish Academy of SciencesM.Curie Sklodowskiej 34Zabrze 41-819Poland Center for energy and environmental Technologies VŠB-Technical University of Ostrava17.Listopadu 15Ostrava 70833Czech Republic State Key Laboratory of Crystal Materials Center of Bio&Micro/Nano Functional MaterialsShandong UniversityJinan 250100China Dresden Center for Computational Materials Science Technische Universität DresdenDresden 01062Germany Dresden Center for Intelligent Materials(GCL DCIM) Technische Universität DresdenDresden 01062Germany Institute for Materials Science and Max Bergmann Center of Biomaterials Technische Universität DresdenDresden 01069Germany Center for Advancing electronics Dresden Technische Universität DresdenDresden 01069Germany

The van der Waals heterostructures have evolved as novel materials for complementing the Si-based semiconductor ***-10 noble metal dichalcogenides(e.g.,PtS_(2),PtSe_(2),PdS_(2),and PdSe_(2))have been listed into two-dimensional(2D)materials toolkit to assemble van der Waals *** them,PdSe_(2) demonstrates advantages of high stability in air,high mobility,and wide tunable ***,the regulation of p-type doping of PdSe_(2) remains unsolved problem prior to fabricating p–n junction as a fundamental platform of semiconductor ***,a quantitative method for the controllable doping of PdSe_(2) is yet to be *** this study,the doping level of PdSe_(2) was correlated with the concentration of Lewis acids,for example,SnCl_(4),used for *** the transfer characteristics,the threshold voltage(the gate voltage corresponding to the minimum drain current)increased after SnCl_(4) soaking ***_(2) transistors were soaked in SnCl_(4) solutions with five different *** threshold voltages from the as-obtained transfer curves were extracted for linear fitting to the threshold voltage versus doping concentration correlation *** study provides in-depth insights into the controllable p-type doping of PdSe_(2).It may also push forward the research of the regulation of conductivity behaviors of 2D materials.

关键词： two-dimensional(2D)materials Lewis acid treatment p-type doping field-effect transistors transfer characteristic

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CFO与供应链管理

新理财（公司理财） 2024年第1期 83-85页

作者： thomas G.Canace Ayaz Jaffer Paul e.Juras 不详

CFO和财务团队完全有能力应对长期供应链扰动给现金流和盈利能力带来的挑战。在经历了新冠疫情带来的供应链扰动后,首席财务官(CFO)和企业都在猜测供应链问题引发的一系列影响何时才能过去。但供应链问题并未随疫情的结束而结束,仍在不... 详细信息

CFO和财务团队完全有能力应对长期供应链扰动给现金流和盈利能力带来的挑战。在经历了新冠疫情带来的供应链扰动后,首席财务官(CFO)和企业都在猜测供应链问题引发的一系列影响何时才能过去。但供应链问题并未随疫情的结束而结束,仍在不断加剧,导致企业无力满足新冠疫情期间被抑制的客户需求,也阻碍了企业的收入增长。

关键词：供应链管理现金流财务团队 CFO 供应链问题盈利能力客户需求疫情

Unmet supportive care needs in families of children with chronic health conditions: an Australian cross‑sectional study

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World Journal of Pediatrics 2023年第12期19卷 1181-1191页

作者： Sangeetha thomas Linda K.Byrne Nicholas P.Ryan Christel Hendrieckx Victoria white School of Psychology Faculty of HealthDeakin UniversityMelbourneVIC 3125Australia Department of Paediatrics University of MelbourneMelbourneVICAustralia Australian Centre for Behavioural Research in Diabetes MelbourneVICAustralia Institute of Health Transformation Deakin UniversityMelbourneVICAustralia Cancer Council Victoria MelbourneVICAustralia

Background The aim of this study was to identify similarities and diferences in the unmet supportive care needs(USCN)of families of children with major chronic health conditions(CHCs)using a universal need assessment *** A cross-sectional online survey involving parents of children with congenital heart disease(CHD),type 1 diabetes mellitus(T1D),cancer,and asthma diagnosed within the last 5 years recruited via social media and support ***-four items assessing the USCN across six domains(care needs,physical and social needs,informational needs,support needs,fnancial needs,child-related emotional needs)were responded to on a 4-point Likert scale[no need(1)to high need(4)].Descriptive statistics identifed the level of need,and linear regressions identifed factors associated with higher need domain *** to small numbers,the asthma group was excluded from comparisons across *** One hundred and ninety-four parents completed the survey(CHD:n=97,T1D:n=50,cancer:n=39,and asthma:n=8).Parents of children with cancer were most likely to report at least one USCN(92%),followed by parents of children with T1D(62%).The fve most commonly reported USCN across CHCs were drawn from four domains:child-related emotional,support,care,and *** need items were included in the top fve needs for all conditions.A higher USCN was associated with a greater frequency of hospital visits and the absence of parental *** Using a universal need assessment tool,this is one of the frst studies to characterize USCN in families of children diagnosed with common *** proportions endorsing diferent needs varied across conditions,the most endorsed needs were similar across the illness *** suggests that support programs or services could be shared across diferent CHCs.

关键词： Children Chronic illness Need assessment Unmet supportive care needs

Templating core-shell particles using metal ion-chelating biosurfactants

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Particuology 2022年第5期20卷 145-152页

作者： Ching-Min Yeh thomas Jarrett Yuan Gao Chun-Xia Zhao Andrew Whittaker Frank Sainsbury Alison L.white Australian Institute of Bioengineering and Nanotechnology The University of QueenslandSt.LuciaQueensland4072Australia ARC Centre of excellence in Convergent Bio-Nano Science and Technology The University of QueenslandSt Lucia4072Australia CSIRO Probing Biosystems Future Science Platform BrisbaneAustralia Centre for Cell Factories and Biopolymers Griffith Institute for Drug DiscoveryGriffith UniversityBrisbaneQLD4111 Australia

Designer biosurfactants can be used to stabilise and functionalise *** particularly promising use is the stabilisation of oil-in-water emulsions,enabling fine tuning physical,chemical and biological surface *** ability of emulsion systems to carry high payloads makes them attractive for applications in medicine,food and fragrances,and ***,they have limited long-term *** we sought to use the metal ion-chelating ability of the biosurfactant peptide,AM1,to precipitate the formation of a gold metal shell on AM1-stabilised emulsions by electroless *** found that replacing the commonly used zinc(Ⅱ)with palladium(Ⅱ)for coordination by histidine residues of adjacent AM1 peptides produced interfacial films that maintained elasticity at acidic *** NMR suggested a coordination mechanism independent of the imidazole ring of the *** of emulsions at low pH enabled the deposition of a gold shell,albeit by an unexpected *** propose that gold nanoparticles forming in bulk are adsorbed onto the peptide-stabilised interface,accumulating into a particulate *** resulting one-step method for nanoparticle precipitation and shell formation will be useful for the creation of biocompatible core-shell particles for applications where large payloads of hydrophobic active compounds require stability over long time periods.

关键词： Biosurfactants emulsion Core-shell particles electroless plating Histidine Interfacial elasticity

When nets meet environmental DNA metabarcoding:integrative approach to unveil invertebrate community patterns of hypersaline lakes

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Journal of Oceanology and Limnology 2023年第4期41卷 1331-1340页

作者： Matthew A.CAMPBeLL Alex LAINI Nicole e.white Morten e.ALLeNTOFT Mattia SACCÒ Trace and environmental DNA(TrenD)Laboratory School of Molecular and Life SciencesCurtin UniversityPerth 6102WAAustralia Department of Life Sciences and Systems Biology University of TurinTurin 10124Italy Subterranean Research and Groundwater ecology(SuRGe)Group Trace and Environmental DNA(TrEnD)LaboratorySchool of Molecular and Life SciencesCurtin UniversityPerth 6102WAAustralia Lundbeck Foundation GeoGenetics Centre Globe InstituteUniversity of CopenhagenCopenhagen 1353Denmark

Saline and hypersaline wetlands account for almost half of the volume of inland water *** provide pivotal habitat for a vast range of species,including crucial ecosystem services for humans such as carbon sink storage and extractive resource *** their importance,effective ecological assessment is in its infancy compared to current conventional surveys carried out in freshwater *** integration of environmental DNA(eDNA)analysis and traditional techniques has the potential to transform biomonitoring processes,particularly in remote and understudied saline *** this context,this preliminary study aims to explore the potential of eDNA coupled with conventional approaches by targeting five hypersaline lakes at Rottnest Island(Wadjemup)in Western *** focused on the invertebrate community,a widely accepted key ecological indicator to assess the conservational status in rivers and *** combination of metabarcoding with morphology-based taxonomic analysis described 16 taxa belonging to the orders Anostraca,Diptera,Isopoda,and ***-based diversity assessment revealed more taxa at higher taxonomic resolution than the morphology-based taxonomic ***,certain taxa(i.e.,ephydridae,Stratyiomidae,Ceratopogonidae)were only identified via net ***,our results indicate that great potential resides in combining conventional net-based surveys with novel eDNA approaches in saline and hypersaline ***,urgent and effective conservational frameworks are required to contrast the enormous pressure that these ecosystems are increasingly *** investigations at larger spatial temporal scales will allow consolidation of robust,reliable,and affordable biomonitoring frameworks in the underexplored world of saline wetlands.

关键词： macroinvertebrate hypersaline e nvironmental DNA(eDNA) conservation ecological survey community composition

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evaluation of Growth Rate of Invasive Aquatic Macrophytes and Contribution to Its Use in Organic Fertilizer Production: A Case of eicchornia crassipes (Mart.) Solms, 1883 in the Lobé Creek (Littoral-Cameroon)

疯狂英语·初中天地 2024年第2期

作者： e.B.white

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Open Journal of ecology 2024年第7期14卷 571-583页

作者： Roland Didier Nwamo Gordon Nwutih Ajonina Tapite Chanel Yamkou Kopmou thomas efole ewoukem Minette Tomedi eyango Department of Aquatic ecosystems Management Institute of Fisheries and Aquatic Sciences at Yabassi University of Douala Douala Cameroon Cameroon Wildlife Conservation Society Mangrove & Coastal Wetlands Research Centre Mouanko Cameroon Department of Forestry Faculty of Agronomy and Agricultural Sciences University of Dschang Dschang Cameroon Department of Aquaculture Institute of Fisheries and Aquatic Sciences at Yabassi University of Douala Douala Cameroon

From 20 January to 20 July 2023, a study was carried out on the Lobé Creek, a waterway subject to considerable natural and man-made pressures, with a negative impact on its biodiversity and habitats. The aim was to evaluate the growth rate of invasive aquatic macrophytes and their contribution to the use of organic fertilisers: a case of eicchornia crassipes (Mart.) Solms, 1883 in the Lobé Creek (Littoral-Cameroon) with a view to its appropriate use in agronomy. The specific objective was to examine the impact of anthropogenic actions on Lobé Creek, characterise physico-chemical environment of the study area, and evaluate the growth rate of e. crassipes and its chemical composition with a view to producing an organic biofertiliser. The results show that e. crassipes represents a considerable threat to the populations of these localities. As for the physico-chemical parameters, the temperature values vary from 24 ± 1.41˚C to 26.5 ± 1.13˚C;pH from 6.3 ± 0.1 to 7.2 ± 0.07;conductivity and dissolved oxygen vary respectively from 40.7 ± 1.83 µS/cm to 19.6 ± 3.11 µS/cm and from 7.3 ± 0.14 mg/l to 5.8 ± 1.55 mg/l. Its average growth rate varies from 0.69 feet/day to 0.63 feet/day. With regard to the nitrogen, phosphorus and potassium content of water hyacinth plants, the results show that the average total nitrogen content ranges from 6.11 ± 1.59 g/kg to 5.2 ± 2.03 g/kg;total phosphorus, from 0.52 ± 0.54 g/kg to 0.88 ± 0.38 g/kg;and potassium, from 1.43 ± 0.45 g/kg to 2.61 ± 0.89 g/kg.

关键词： eichhornia crassipes Lobé Creek Anthropogenic Actions Physico-Chemical environment Growth Rate Chemical Composition